-
1
-
-
0032523064
-
Integrin signaling: The platelet paradigm
-
Shattil SJ, Kashiwagi H, Pampori N. Integrin signaling: The platelet paradigm. Blood 1998; 91: 2645-57.
-
(1998)
Blood
, vol.91
, pp. 2645-2657
-
-
Shattil, S.J.1
Kashiwagi, H.2
Pampori, N.3
-
2
-
-
0042681786
-
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins
-
Kim M, Carman CV, Springer TA. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science 2003; 301: 1720-5.
-
(2003)
Science
, vol.301
, pp. 1720-1725
-
-
Kim, M.1
Carman, C.V.2
Springer, T.A.3
-
3
-
-
0035041854
-
C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1
-
Takagi J, Erickson HP, Springer TA. C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1. Nat Struct Biol 2001; 8: 412-6.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 412-416
-
-
Takagi, J.1
Erickson, H.P.2
Springer, T.A.3
-
4
-
-
0037031551
-
A structural mechanism of integrin alpha(IIb)beta(3) 'inside-out' activation as regulated by its cytoplasmic face
-
Vinogradova O, Velyvis A, Velyviene A, Hu B, Haas T, Plow E, Qin J. A structural mechanism of integrin alpha(IIb)beta(3) 'inside-out' activation as regulated by its cytoplasmic face. Cell 2002; 110: 587-97.
-
(2002)
Cell
, vol.110
, pp. 587-597
-
-
Vinogradova, O.1
Velyvis, A.2
Velyviene, A.3
Hu, B.4
Haas, T.5
Plow, E.6
Qin, J.7
-
5
-
-
0141865705
-
Talin binding to integrin beta tails: A final common step in integrin activation
-
Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM, Ginsberg MH, Calderwood DA. Talin binding to integrin beta tails: A final common step in integrin activation. Science 2003; 302: 103-6.
-
(2003)
Science
, vol.302
, pp. 103-106
-
-
Tadokoro, S.1
Shattil, S.J.2
Eto, K.3
Tai, V.4
Liddington, R.C.5
de Pereda, J.M.6
Ginsberg, M.H.7
Calderwood, D.A.8
-
6
-
-
1642529548
-
Membrane-mediated structural transitions at the cytoplasmic face during integrin activation
-
Vinogradova O, Vaynberg J, Kong X, Haas TA, Plow EF, Qin J. Membrane-mediated structural transitions at the cytoplasmic face during integrin activation. Proc Natl Acad Sci USA 2004; 101: 4094-9.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4094-4099
-
-
Vinogradova, O.1
Vaynberg, J.2
Kong, X.3
Haas, T.A.4
Plow, E.F.5
Qin, J.6
-
7
-
-
0035805633
-
Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state
-
Lu C, Takagi J, Springer TA. Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state. J Biol Chem 2001; 276: 14642-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 14642-14648
-
-
Lu, C.1
Takagi, J.2
Springer, T.A.3
-
8
-
-
0037197990
-
Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits
-
Weljie AM, Hwang PM, Vogel HJ. Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits. Proc Natl Acad Sci USA 2002; 99: 5878-83.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5878-5883
-
-
Weljie, A.M.1
Hwang, P.M.2
Vogel, H.J.3
-
9
-
-
0029966310
-
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling
-
Hughes PE, Diaz-Gonzalez F, Leong L, Wu C, McDonald JA, Shattil SJ, Ginsberg MH. Breaking the integrin hinge. A defined structural constraint regulates integrin signaling. J Biol Chem 1996; 271: 6571-4.
-
(1996)
J Biol Chem
, vol.271
, pp. 6571-6574
-
-
Hughes, P.E.1
Diaz-Gonzalez, F.2
Leong, L.3
Wu, C.4
McDonald, J.A.5
Shattil, S.J.6
Ginsberg, M.H.7
-
10
-
-
0028285015
-
Integrin cytoplasmic domains mediate inside-out signal transduction
-
O'Toole TE, Katagiri Y, Faull RJ, Peter K, Tamura R, Quaranta V, Loftus JC, Shattil SJ, Ginsberg MH. Integrin cytoplasmic domains mediate inside-out signal transduction. J Cell Biol 1994; 124: 1047-59.
-
(1994)
J Cell Biol
, vol.124
, pp. 1047-1059
-
-
O'Toole, T.E.1
Katagiri, Y.2
Faull, R.J.3
Peter, K.4
Tamura, R.5
Quaranta, V.6
Loftus, J.C.7
Shattil, S.J.8
Ginsberg, M.H.9
-
11
-
-
0029945019
-
A deletion in the alpha subunit locks platelet integrin alpha IIb beta 3 into a high affinity state
-
Peter K, Bode C. A deletion in the alpha subunit locks platelet integrin alpha IIb beta 3 into a high affinity state. Blood Coagul Fibrinolysis 1996; 7: 233-6.
-
(1996)
Blood Coagul Fibrinolysis
, vol.7
, pp. 233-236
-
-
Peter, K.1
Bode, C.2
-
12
-
-
22344438374
-
Importance of integrin LFA-1 deactivation for the generation of immune responses
-
Semmrich M, Smith A, Feterowski C, Beer S, Engelhardt B, Busch D, Bartsch B, Laschinger M, Hogg N, Pfeffer K, Holzmann B. Importance of integrin LFA-1 deactivation for the generation of immune responses. J Exp Med 2005; 201: 1987-98.
-
(2005)
J Exp Med
, vol.201
, pp. 1987-1998
-
-
Semmrich, M.1
Smith, A.2
Feterowski, C.3
Beer, S.4
Engelhardt, B.5
Busch, D.6
Bartsch, B.7
Laschinger, M.8
Hogg, N.9
Pfeffer, K.10
Holzmann, B.11
-
13
-
-
0031046185
-
Identification of a novel calcium-binding protein that interacts with the integrin alpha IIb cytoplasmic domain
-
Naik MU, Patel PM, Parise LV. Identification of a novel calcium-binding protein that interacts with the integrin alpha IIb cytoplasmic domain. J Biol Chem 1997; 272: 4651-4.
-
(1997)
J Biol Chem
, vol.272
, pp. 4651-4654
-
-
Naik, M.U.1
Patel, P.M.2
Parise, L.V.3
-
14
-
-
0037047274
-
Ancient ubiquitous protein 1 binds to the conserved membrane-proximal sequence of the cytoplasmic tail of the integrin alpha subunits that plays a crucial role in the inside-out signaling of alpha IIbbeta 3
-
Kato A, Kawamata N, Tamayose K, Egashira M, Miura R, Fujimura T, Murayama K, Oshimi K. Ancient ubiquitous protein 1 binds to the conserved membrane-proximal sequence of the cytoplasmic tail of the integrin alpha subunits that plays a crucial role in the inside-out signaling of alpha IIbbeta 3. J Biol Chem 2002; 277: 28934-41.
-
(2002)
J Biol Chem
, vol.277
, pp. 28934-28941
-
-
Kato, A.1
Kawamata, N.2
Tamayose, K.3
Egashira, M.4
Miura, R.5
Fujimura, T.6
Murayama, K.7
Oshimi, K.8
-
15
-
-
4043182014
-
Protein phosphatase 1 associates with the integrin alpha IIb subunit and regulates signaling
-
Vijayan KV, Liu Y, Li TT, Bray PF. Protein phosphatase 1 associates with the integrin alpha IIb subunit and regulates signaling. J Biol Chem 2004; 279: 33039-42.
-
(2004)
J Biol Chem
, vol.279
, pp. 33039-33042
-
-
Vijayan, K.V.1
Liu, Y.2
Li, T.T.3
Bray, P.F.4
-
16
-
-
3042549223
-
ICln, a novel integrin alphaIIbbeta3-associated protein, functionally regulates platelet activation
-
Larkin D, Murphy D, Reilly DF, Cahill M, Sattler E, Harriott P, Cahill DJ, Moran N. ICln, a novel integrin alphaIIbbeta3-associated protein, functionally regulates platelet activation. J Biol Chem 2004; 279: 27286-93.
-
(2004)
J Biol Chem
, vol.279
, pp. 27286-27293
-
-
Larkin, D.1
Murphy, D.2
Reilly, D.F.3
Cahill, M.4
Sattler, E.5
Harriott, P.6
Cahill, D.J.7
Moran, N.8
-
17
-
-
1442331993
-
Integrin activation
-
Calderwood DA. Integrin activation. J Cell Sci 2004; 117: 657-66.
-
(2004)
J Cell Sci
, vol.117
, pp. 657-666
-
-
Calderwood, D.A.1
-
18
-
-
12544252996
-
Distinct roles of the alpha and beta subunits in the functions of integrins alphaMbeta2
-
Solovjov D, Pluskota E, Plow E. Distinct roles of the alpha and beta subunits in the functions of integrins alphaMbeta2. J Biol Chem 2005; 280: 1336-45.
-
(2005)
J Biol Chem
, vol.280
, pp. 1336-1345
-
-
Solovjov, D.1
Pluskota, E.2
Plow, E.3
-
19
-
-
0034629578
-
The cytoplasmic domain of the alpha1 integrin subunit influences stress fiber formation via the conserved GFFKR motif
-
Vossmeyer D, Kaufmann C, Loster K, Lucka L, Horstkorte R, Reutter W, Danker K. The cytoplasmic domain of the alpha1 integrin subunit influences stress fiber formation via the conserved GFFKR motif. Exp Cell Res 2000; 256: 321-7.
-
(2000)
Exp Cell Res
, vol.256
, pp. 321-327
-
-
Vossmeyer, D.1
Kaufmann, C.2
Loster, K.3
Lucka, L.4
Horstkorte, R.5
Reutter, W.6
Danker, K.7
-
20
-
-
33644887430
-
Evidence for a differential functional regulation of the two beta3 integrin alphavbeta3 and alphaIIb
-
Ahrens IG, Moran N, Aylward K, Meade G, Moser M, Assefa D, Fitzgerald DJ, Bode C, Peter K. Evidence for a differential functional regulation of the two beta3 integrin alphavbeta3 and alphaIIb. Exp Cell Res 2006; 312: 925-37.
-
(2006)
Exp Cell Res
, vol.312
, pp. 925-937
-
-
Ahrens, I.G.1
Moran, N.2
Aylward, K.3
Meade, G.4
Moser, M.5
Assefa, D.6
Fitzgerald, D.J.7
Bode, C.8
Peter, K.9
-
21
-
-
19344365790
-
The beta3 subunit of the integrin alphaIIbbeta3 regulates alphaIIb-mediated outside-in signaling
-
Liu J, Jackson CW, Gruppo RA, Jennings LK, Gartner TK. The beta3 subunit of the integrin alphaIIbbeta3 regulates alphaIIb-mediated outside-in signaling. Blood 2005; 105: 4345-52.
-
(2005)
Blood
, vol.105
, pp. 4345-4352
-
-
Liu, J.1
Jackson, C.W.2
Gruppo, R.A.3
Jennings, L.K.4
Gartner, T.K.5
-
22
-
-
1542544886
-
A palmitylated peptide derived from the glycoprotein Ib beta cytoplasmic tail inhibits platelet activation
-
Martin K, Meade G, Moran N, Shields DC, Kenny D. A palmitylated peptide derived from the glycoprotein Ib beta cytoplasmic tail inhibits platelet activation. J Thromb Haemost 2003; 1: 2643-52.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 2643-2652
-
-
Martin, K.1
Meade, G.2
Moran, N.3
Shields, D.C.4
Kenny, D.5
-
23
-
-
0032493816
-
A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis
-
Stephens G, O'Luanaigh N, Reilly D, Harriott P, Walker B, Fitzgerald D, Moran N. A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis. J Biol Chem 1998; 273: 20317-22.
-
(1998)
J Biol Chem
, vol.273
, pp. 20317-20322
-
-
Stephens, G.1
O'Luanaigh, N.2
Reilly, D.3
Harriott, P.4
Walker, B.5
Fitzgerald, D.6
Moran, N.7
-
24
-
-
0035933835
-
A membrane-distal segment of the integrin alpha IIb cytoplasmic domain regulates integrin activation
-
Ginsberg MH, Yaspan B, Forsyth J, Ulmer TS, Campbell ID, Slepak M. A membrane-distal segment of the integrin alpha IIb cytoplasmic domain regulates integrin activation. J Biol Chem 2001; 276: 22514-21.
-
(2001)
J Biol Chem
, vol.276
, pp. 22514-22521
-
-
Ginsberg, M.H.1
Yaspan, B.2
Forsyth, J.3
Ulmer, T.S.4
Campbell, I.D.5
Slepak, M.6
-
25
-
-
0042388099
-
Platelet alpha2beta1 integrin activation: Contribution of ligand internalization and the alpha2-cytoplasmic domain
-
Wang Z, Leisner TM, Parise LV. Platelet alpha2beta1 integrin activation: contribution of ligand internalization and the alpha2-cytoplasmic domain. Blood 2003; 102: 1307-15.
-
(2003)
Blood
, vol.102
, pp. 1307-1315
-
-
Wang, Z.1
Leisner, T.M.2
Parise, L.V.3
-
26
-
-
27744564167
-
Two functional active conformations of the integrin alpha2beta1, depending on activation condition and cell type
-
Van de Walle G, Vanhoorelbeke KZM, Illyes E, Baert J, Pareyn I, Deckmyn H. Two functional active conformations of the integrin alpha2beta1, depending on activation condition and cell type. J Biol Chem 2005; 280: 36873-82.
-
(2005)
J Biol Chem
, vol.280
, pp. 36873-36882
-
-
Van de Walle, G.1
Vanhoorelbeke, K.Z.M.2
Illyes, E.3
Baert, J.4
Pareyn, I.5
Deckmyn, H.6
-
27
-
-
0022699646
-
Solid phase synthesis
-
Merrifield B. Solid phase synthesis. Science 1986; 232: 341-7.
-
(1986)
Science
, vol.232
, pp. 341-347
-
-
Merrifield, B.1
-
28
-
-
33947091567
-
The 9-fluorenylmethoxycarbonyl amino protecting group
-
Carpino LA, Han GY. The 9-fluorenylmethoxycarbonyl amino protecting group. J Org Chem 1972; 37: 3404-9.
-
(1972)
J Org Chem
, vol.37
, pp. 3404-3409
-
-
Carpino, L.A.1
Han, G.Y.2
-
29
-
-
4744374646
-
Antimicrobial activity of arginine- and tryptophan-rich hexapeptides: The effects of aromatic clusters, D-amino acid substitution and cyclization
-
Wessolowski A, Bienert M, Dathe M. Antimicrobial activity of arginine- and tryptophan-rich hexapeptides: The effects of aromatic clusters, D-amino acid substitution and cyclization. J Peptide Res 2004; 64: 159-69.
-
(2004)
J Peptide Res
, vol.64
, pp. 159-169
-
-
Wessolowski, A.1
Bienert, M.2
Dathe, M.3
-
30
-
-
0033023173
-
Noninvasive intracellular delivery of functional peptides and proteins
-
Hawiger J. Noninvasive intracellular delivery of functional peptides and proteins. Curr Opin Chem Biol 1999; 3: 89-94.
-
(1999)
Curr Opin Chem Biol
, vol.3
, pp. 89-94
-
-
Hawiger, J.1
-
31
-
-
0029999551
-
Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs
-
Liu KY, Timmons S, Lin YZ, Hawiger J. Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs. Proc Natl Acad Sci USA 1996; 93: 11819-24.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11819-11824
-
-
Liu, K.Y.1
Timmons, S.2
Lin, Y.Z.3
Hawiger, J.4
-
32
-
-
24944573100
-
A high-throughput assay for assessing the cell permeability of combinatorial libraries
-
Yu P, Liu B, Kodadek T. A high-throughput assay for assessing the cell permeability of combinatorial libraries. Nat Biotechnol 2005; 23: 746-51.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 746-751
-
-
Yu, P.1
Liu, B.2
Kodadek, T.3
-
33
-
-
19444382074
-
The engineering of membrane-permeable peptides
-
Carrigan CN, Imperiali B. The engineering of membrane-permeable peptides. Anal Biochem 2005; 341: 290-8.
-
(2005)
Anal Biochem
, vol.341
, pp. 290-298
-
-
Carrigan, C.N.1
Imperiali, B.2
-
34
-
-
1442277113
-
Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif
-
Reilly D, Larkin D, Devocelle M, Fitzgerald DJ, Moran N. Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif. Platelets 2004; 15: 43-54.
-
(2004)
Platelets
, vol.15
, pp. 43-54
-
-
Reilly, D.1
Larkin, D.2
Devocelle, M.3
Fitzgerald, D.J.4
Moran, N.5
-
35
-
-
0031181648
-
The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1
-
Lu CF, Springer TA. The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1. J Immunol 1997; 159: 268-78.
-
(1997)
J Immunol
, vol.159
, pp. 268-278
-
-
Lu, C.F.1
Springer, T.A.2
-
36
-
-
16644396938
-
A specific interface between integrin transmembrane helices and affinity for ligand
-
Luo BH, Springer TA, Takagi J. A specific interface between integrin transmembrane helices and affinity for ligand. PLoS Biol 2004; 2: 776-86.
-
(2004)
PLoS Biol
, vol.2
, pp. 776-786
-
-
Luo, B.H.1
Springer, T.A.2
Takagi, J.3
-
37
-
-
0033731119
-
Integrin cytoplasmic domain-binding proteins
-
Liu S, Calderwood DA, Ginsberg MH. Integrin cytoplasmic domain-binding proteins. J Cell Sci 2000; 113: 3563-71.
-
(2000)
J Cell Sci
, vol.113
, pp. 3563-3571
-
-
Liu, S.1
Calderwood, D.A.2
Ginsberg, M.H.3
-
38
-
-
25844511241
-
A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent Rho A activation during cell spreading
-
Salsmann A, Schaffner-Reckinger EFK, Plancon S, Kieffer N. A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent Rho A activation during cell spreading. J Biol Chem 2005; 280: 33610-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 33610-33619
-
-
Salsmann, A.1
Schaffner-Reckinger, E.F.K.2
Plancon, S.3
Kieffer, N.4
-
39
-
-
2342562452
-
Suppression of integrin activation by the membrane-distal sequence of the integrin alphaIIb cytoplasmic tail
-
Yamanouchi J, Hato T, Tamura T, Fujita S. Suppression of integrin activation by the membrane-distal sequence of the integrin alphaIIb cytoplasmic tail. Biochem J 2004; 379: 317-23.
-
(2004)
Biochem J
, vol.379
, pp. 317-323
-
-
Yamanouchi, J.1
Hato, T.2
Tamura, T.3
Fujita, S.4
|