Lipopolysaccharide-induced decreased protein S expression in liver cells is mediated by MEK/ERK signaling and NFκB activation: Involvement of membrane-bound CD14 and toll-like receptor-4

Journal of Thrombosis and Haemostasis

Volumn 4, Issue 8, 2006, Pages 1763-1773

  Hayashi, T ^a   Kishiwada, M ^a   Fujii, K ^a   Yuasa, H ^a   Nishioka, J ^a   Ido, M ^a   Gabazza, E C ^a   Suzuki, Koji ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Lipopolysaccharide; Protein S; Sinusoidal endothelial cells

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN S; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN DETECTION; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTOXEMIA; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE EXPRESSION REGULATION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER SINUSOID; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SIGNAL TRANSDUCTION; THROMBOSIS;

ANIMALS; ANTICOAGULANTS; ANTIGENS, CD14; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIPOPOLYSACCHARIDES; LIVER; MALE; MAP KINASE KINASE KINASES; NF-KAPPA B; PROTEIN S; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 33746588173     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2006.02042.x     Document Type: Article

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