Effects of calcitonin gene-related peptide on vascular resistance in rats: Role of sex steroids

American Journal of Physiology

Volumn 276, Issue 6 PART 2, 1999, Pages

  Grewal, Michelle ^b   Cuevas, Jams ^a   Chaudhuri, Gautam ^b   Nathan, Lauren ^a  

^a Department of Obstetrics and Gynecology ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33746564659     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Abdelrahman, A., Y. X. Wang, S. D. Chang, and C. C. Y. Pang. Mechanisms of the vasodilator action of calcitonin generelated peptide in conscious rats. Br. J. Pharmacol. 106: 45-48, 1992.
2. Coeskun, T., A. Sevinec, I. Tevetoaglu, I. Alican, H. Kurtel, and B. C. Yeagen. Delayed gastric emptying in conscious male rats following chronic estrogen and progesterone treatment. Res. Exp. Med. (Berl.) 195:49-54,1995.
3. DiPette, D. J., K. N. Westlund, and O. B. Holland. Dietary calcium modulates spinal cord content of calcitonin gene-related peptide in the rat. Neurosci. Lett. 95:335-340,1988.
4. Dong, Y. L., P. R. Gangula, L. Fang, S. J. Wimalawansa, and C. Yallampalli. Uterine relaxation responses to calcitonin generelated peptide and calcitonin gene-related peptide receptors decreased during labor in rats. Am. J. Obstet. Gynecol. 179: 497-506,1998.
5. Furchgott, R. F., and J. V. Zawadzki. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373-376,1980.
6. Gangula, P. R., S. C. Supowit, S. J. Wimalawansa, H. Zhao, D. M. Hallman, D. J. DiPette, and C. Yallampalli. Calcitonin gene-related peptide is a depressor in A-nitro-L-arginine methyl ester-induced hypertension during pregnancy. Hypertension 29: 248-253,1997.
7. Gangula, P. R., S. J. Wimalawansa, and C. Yallampalli. Progesterone up-regulates vasodilator effects of calcitonin generelated peptide in -nitro-L-arginine methyl ester-induced hypertension. Am. J. Obstet. Gynecol. 176:894-900,1997.
8. Gangula, P. R. R., H. Zhao, S. Supowit, S. Wimalawansa, D. DiPette, and C. Yallampalli. Pregnancy and steroid hormones enhance the vasodilation responses to CGRP in rats. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H284-H288,1999.
9. Gibson, S. J., J. M. Polak, S. R. Bloom, I. M. Sabate, P. M. Mulderry, M. A. Ghatei, G. P. McGregor, J. F. Morrison, J. S. Kelly, and R. M. Evans, and M. G. Rosenfeld. Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species. J. Neurosci. 4:3101-3111,1984.
10. Girgis, S. I., D. W. Macdonald, J. C. Stevenson, P. M. Bevis, C. Lynch, S. J. Wimalawansa, C. H. Self, H. R. Morris, and I. Maclntyre. Calcitonin gene-related peptide: potent vasodilator and major product of calcitonin gene. Lancet 2:14-16,1985.
11. Giuliani, S., S. J. Wimalawansa, and C. A. Maggi. Involvement of multiple receptors in the biological effects of calcitonin gene-related peptide and amylin in rat and guinea-pig preparations. Br. J. Pharmacol. 107:510-514,1992.
12. Grace, G. C., G. J. Dusting, B. E. Kemp, and T. J. Martin. Endothelium and the vasodilator action of rat calcitonin generelated peptide CGRP. Br. J. Pharmacol. 91: 729-733,1987.
13. Gray, D. W., and I. Marshall. Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta. Ear. J. Pharmacol. 212: 37-42, 1992.
14. Gray, D. W., I. Marshall, C. Bose, R. Foulkes, and B. Hughes. Subtypes of the calcitonin gene-related peptide (CGRP) receptor in vascular tissues (Abstract), r. J. Pharmacol. 102: 189P, 1991.
15. Hayashi, T., J. M. Fukuto, L. J. Ignarro, and G. Chaudhuri. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis. Proc. Natl. Acad. Sci. USA 89:11259-11263,1992.
16. Jaffe, R. B. Fetoplacental endocrine and metabolic physiology. Clin. Perinatal. 10:669-693,1983.
17. Jansen, L., L. Nilsson, and L. Edvinsson (Editors). Calcitonin gene-related peptide and blood vessels. In: Vascular Innervation and Receptor Mechanisms. New York: Academic, 1993, p. 263279.
18. Kubota, M., J. M. Moseley, L. Butera, G. J. Dusting, P. S. MacDonald, and T. J. Martin. Calcitonin gene-related peptide stimulates cyclic AMP formation in rat aortic smooth muscle cells. Biochem. Biophys. Res. Commun. 132:88-94,1985.
19. Lockitch, G. Clinical biochemistry of pregnancy. Crit. Rev. Clin. Lab. Sci. 34: 67-139,1997.
20. Moluaar, M., and F. Hertelendy. AT-nitro-L-arginine, an inhibitor of nitric oxide synthesis, increases blood pressure in rats and reverses the pregnancy-induced refractoriness to vasopressor agents. Am. J. Obstet. Gynecol. 166:1560-1567,1992.
21. Nathan, L., J. Cuevas, and G. Chaudhuri. The role of nitric oxide in the altered vascular reactivity of pregnancy in the rat. Br. J. Pharmacol. 114:955-960,1995.
22. Nelson, S. H., O. S. Steinsland, and M. S. Suresh. Possible physiologic role of calcitonin gene-related peptide in the human uterine artery. Am. J. Obstet. Gynecol. 168: 605-611,1993.
23. Pan, Z. R., M. D. Lindheimer, J. Bailin, and W. M. Barron. Regulation of blood pressure in pregnancy: pressor system blockade and stimulation. Am. J. Physiol. 258 (Heart Circ. Physiol. 27): H1559-H1572,1990.
24. Quinon, R., D. Van Rossum, Y. Dumont, S. St. Pierre, and A. Fournier. Characterization of CGRPi and CGRP2 receptor subtypes. Ann. NYAcad. Sci. 657:88-105,1991.
25. Rosenfeld, M. G., J. J. Mermod, S. G. Amara, L.A. Swanson, P. E. Sawchenko, J. Rivier, W. W. Vale, and R. M. Evans. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature 304: 129-135, 1983.
26. Saito, A., S. Kimura, and K. Goto. Calcitonin gene-related peptide as potential neurotransmitter in guinea pig right atrium. Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H693-H698,1986.
27. Sladek, S. M., R. R. Magness, and K. P. Conrad. Nitric oxide and pregnancy. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R441-R463,1997.
28. Stevenson, J. C., D. W. Macdonald, R. C. Warren, M. W. Booker, and M. I. Whitehead. Increased concentration of circulating calcitonin gene related peptide during normal human pregnancy. Br. Med. J. (Clin. Res. Ed.) 293:1329-1330,1986.
29. Tan, D. Y., L. Z. Zhang, Y. T. Zhao, D. Zhao, and J. Tang. Involvement of nitric oxide in the vasodilator and depressor effect of calcitonin gene-related peptide. Chin. Med. J. (Engl.) 107:745-749,1994.
30. Wimalawansa, S. J. Calcitonin gene-related peptide and its receptors: molecular genetics, physiology, pathophysiology, and therapeutic potentials. Endocr. Rev. 17:533-585,1996.
31. Wimalawansa, S. J. The effects of neonatal capsaicin on plasma levels and tissue contents of CGRP. Peptides 14: 247-252,1993.
32. Wimalawansa, S. J., P. C. Emson, and I. Maclntyre. Regional distribution of calcitonin gene-related peptide and its specific binding sites in rats with particular reference to the nervous system. Neuroendocrinology 46:131-136,1987.
33. Wimalawansa, S. J., and I. Maclntyre. Calcitonin generelated peptide and its specific binding sites in the cardiovascular system of rat. Int. J. Cardiol. 20: 29-37,1988.
34. Wimalawansa, S. J., and I. Macintyre. Heterogeneity of plasma calcitonin gene-related peptide: partial characterisation of immunoreactive forms. Peptides 9:407-410,1988.
35. Wimalawansa, S. J., H. R. Morris, and I. Maclntyre. Both alpha- and beta-calcitonin gene-related peptides are present in plasma, cerebrospinal fluid and spinal cord in man. J. Mol. Endocrinol. 3:247-252,1989.
36. Yallampalli, C., Y. L. Dong, and S. J. Wimalawansa. Calcitonin gene-related peptide reverses the hypertension and significantly decreases the fetal mortality in pre-eclampsia rats induced by JV-nitro-L-arginine methyl ester. Hum. Reprod. 11: 895-9,1996.