Progesterone up-regulates vasodilator effects of calcitonin gene- related peptide in N(G)-nitro-L-arginine methyl ester-induced hypertension

American Journal of Obstetrics and Gynecology

Volumn 176, Issue 4, 1997, Pages 894-900

  Gangula, P R R ^a   Wimalawansa, S J ^a   Yallampalli, C ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Calcitonin gene related peptide; postpartum; preeclampsia; pregnancy; progesterone; vasodilation

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; N(G) NITROARGININE METHYL ESTER; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; FEMALE; FETUS MORTALITY; HYPERTENSION; INTRAUTERINE GROWTH RETARDATION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; VASODILATATION;

EID: 0030985283     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(97)70618-5     Document Type: Article

References (22)

1. JM Roberts Pregnancy related hypertension 2nd ed RK Creasy R Resnik Maternal-fetal medicine: principles and practice 1989 WB Saunders Philadelphia 777 823
2. HCS Wallenburg Hemodynamics in hypertensive pregnancy PC Rubin Hypertension in pregnancy: handbook of hypertension 10 1988 Elsevier Amsterdam 66 101
3. C Yallampalli RE Garfield Inhibition of nitric oxide synthesis in rats during pregnancy produces symptoms identical to preeclampsia Am J Obstet Gynecol 169 1993 1316 1320
4. I Buhimschi C Yallampalli K Chawalisz RE Garfield Pre-eclampsia–like conditions produced by nitric oxide inhibition: effects of L-arginine, D-arginine and steroid hormones Hum Reprod 10 1995 2723 2730
5. M Molnár T Sütó T Tóth F Hertelendy Prolonged blockade of nitric oxide synthesis in gravid rats produced sustained hypertension proteinuria, thrombocytopenia, and intrauterine growth retardation Am J Obstet Gynecol 170 1994 1458 1466
6. MG Rosenfeld JJ Mermod SG Amara LW Swanson PE Sawchenko J Rivier Production of a novel neuropeptide encoded by the calcitonin gene via tissue specific RNA processing Nature 304 1983 129 135
7. SJ Wimalawansa Calcitonin gene–related peptide and its receptors: molecular genetics, physiology, pathophysiology, and therapeutic potentials Endocrine Rev 17 1996 533 585
8. DJ DiPette SJ Wimalawansa Cardiovascular actions of calcitonin gene–related peptide MF Cragg LV Avioli Calcium regulating hormones and cardiovascular function 1995 CRC Baltimore 239 252
9. SI Girgis DWR MacDonald JC Stevenson PJ Bevis C Lynch SJ Wimalawansa Calcitonin gene–related peptide: potent vasodilator and major product of the calcitonin gene Lancet 2 1985 14 16
10. SJ Wimalawansa I MacIntyre Heterogeneity of plasma calcitonin gene–related peptide: partial characterization of immunoreactive forms Peptides 9 1988 407 410 a
11. SJ Wimalawansa HR Morris I MacIntyre Both α- and β-calcitonin gene–related peptides are present in plasma, cerebrospinal fluid and spinal cord in man J Mol Endocrinol 3 1989 247 252
12. SJ Wimalawansa PC Emeson I MacIntyre Regional distribution of calcitonin gene–related peptide and its specific binding sites in rats with particular reference to the nervous system Neuroendocrinology 46 1987 131 146
13. SJ Wimalawansa Effects of neonatal capsaicin therapy on plasma contents and tissue levels of immunoreactive-CGRP Peptides 14 1993 247 252
14. SJ Wimalawansa I MacIntyre Calcitonin gene–related peptide and its specific binding sites in the cardiovascular system of rat Int J Cardiol 20 1988 29 37 b
15. Y Hirata Y Takagi S Takata Y Fukuda H Yoshimi T Fujita Calcitonin gene–related peptide receptor in cultured vascular smooth muscle and endothelial cells Biochem Biophys Res Commun 151 1988 1113 1121
16. G-nitro-L-arginine methyl ester Hum Reprod 11 1996 895 899
17. J Dogterom W De Jong Diminished pressor response to noradrenaline of the perfused tail artery of pregnancy rats Eur J Pharmacol 25 1974 267 269
18. JC Stevenson DWR MacDonald RC Warren MW Booker MI Whitehead Increased concentration of circulating calcitonin gene–related peptide during normal human pregnancy BMJ 293 1986 1329 1330
19. G Saggese S Bertelloni G Baroncelli A Pelletti U Benedetti Evaluation of a peptide family encoded by the calcitonin gene in selected healthy pregnant women: a longitudinal study Horm Res 34 1990 240 244
20. SH Nelson OS Steinsland MS Suresh Possible physiologic role of calcitonin gene–related peptide in the human uterine artery Am J Obstet Gynecol 168 1993 605 611
21. L Edvinsson BB Fredholm E Hamel I Jansen C Verrecchia Perivascular peptides relax cerebral arteries concomitant with stimulation of cyclic adenosine monophosphate accumulation or release of an endothelium-derived relaxing factor in the cat Neurosci Lett 58 1985 213 217
22. G Bodelsson M Stjernquist Smooth muscle dilatation in the human uterine artery induced by substance P, vasoactive intestinal polypeptide, calcitonin gene–related peptide and a trial natriuretic peptide: relation to endothelium-derived relaxing substances Hum Reprod 7 1992 1185 1188