Loss of phosphatase activity in Ptp69D alleles supporting axon guidance defects

Journal of Cellular Biochemistry

Volumn 98, Issue 5, 2006, Pages 1296-1307

  Marlo, Joy E ^a,c   Desai, Chand J ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c NONE   (United States)

Author keywords

Axon guidance; Catalytic; DiFMUP; Kinetics; PTP

Indexed keywords

PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE;

ALLELE; ANIMAL CELL; ARTICLE; CATALYSIS; CELL VIABILITY; CENTRAL NERVOUS SYSTEM; DROSOPHILA; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE; GENE MUTATION; NERVE INJURY; NEUROMUSCULAR TRANSMISSION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PTP69D GENE; TANDEM REPEAT;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD45; AXONS; BINDING SITES; CELL LINE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, CELL SURFACE; TEMPERATURE;

EID: 33746392797     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20862     Document Type: Article

References (43)

1. Alonso A, Sasin J, Bottini N, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T. 2004. Protein tyrosine phosphatases in the human genome. Cell 117: 699-711.
2. Andersen JN, Mortensen OH, Peters GH, Drake PG, Iversen LF, Olsen OH, Jansen PG, Andersen HS, Tonks NK, Moller NP. 2001. Structural and evolutionary relationships among protein tyrosine phosphatase domains. Mol Cell Biol 21:7117-7136.
3. Barford D, Das AK, Egloff MP. 1998. The structure and mechanism of protein phosphatases: Insights into catalysis and regulation. Annu Rev Biophys Biomol Struct 27: 133-164.
4. Charbonneau H, Tonks NK. 1992. 1002 protein phosphatases? Annu Rev Cell Biol 8:463-493.
5. Denu JM, Zhou G, Guo Y, Dixon JE. 1995. The catalytic role of aspartic acid-92 in a human dual-specific protein-tyrosine-phosphatase. Biochemistry 34:3396-3403.
6. Denu JM, Lohse DL, Vijayalakshmi J, Saper MA, Dixon JE. 1996. Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis. Proc Natl Acad Sci USA 93:2493-2498.
7. Desai C, Purdy J. 2003. The neural receptor protein tyrosine phosphatase DPTP69D is required during periods of axon outgrowth in Drosophila. Genetics 164:575-588.
8. Desai CJ, Gindhart JG, Jr., Goldstein LS, Zinn K. 1996. Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo. Cell 84:599-609.
9. Desai CJ, Krueger NX, Saito H, Zinn K. 1997a. Competition and cooperation among receptor tyrosine phosphatases control motoneuron growth cone guidance in Drosophila. Development 124:1941-1952.
10. Desai CJ, Sun Q, Zinn K. 1997b. Tyrosine phosphorylation and axon guidance: Of mice and flies. Curr Opin Neurobiol 7:70-74.
11. Ensslen-Craig SE, Brady-Kalnay SM. 2004. Receptor protein tyrosine phosphatases regulate neural development and axon guidance. Dev Biol 275:12-22.
12. Flint AJ, Tiganis T, Barford D, Tonks NK. 1997. Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases. Proc Natl Acad Sci USA 94:1680-1685.
13. Fortin M, Steff AM, Felberg J, Ding I, Schraven B, Johnson P, Hugo P. 2002. Apoptosis mediated through CD45 is independent of its phosphatase activity and association with leukocyte phosphatase-associated phosphoprotein. J Immunol 168:6084-6089.
14. Fox AN, Zinn K. 2005. The heparan sulfate proteoglycan syndecan is an in vivo ligand for the Drosophila LAR receptor tyrosine phosphatase. Curr Biol 15:1701-1711.
15. Garrity PA, Lee CH, Salecker I, Robertson HC, Desai CJ, Zinn K, Zipursky SL. 1999. Retinal axon target selection in Drosophila is regulated by a receptor protein tyrosine phosphatase. Neuron 22:707-717.
16. Gould KL, Ren L, Feoktistova AS, Jennings JL, Link AJ. 2004. Tandem affinity purification and identification of protein complex components. Methods 33;239-244.
17. Guan KL, Dixon JE. 1991. Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate. J Biol Chem 266:17026-17030.
18. Ingebritsen TS, Stewart AA, Cohen P. 1983. The protein phosphatases involved in cellular regulation. 6. Measurement of type-1 and type-2 protein phosphatases in extracts of mammalian tissues; an assessment of their physiological roles. Eur J Biochem 132:297-307.
19. Jia Z, Barford D, Flint AJ, Tonks NK. 1995. Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science 268:1754-1758.
20. Jiang G, den Hertog J, Su J, Noel J, Sap J, Hunter T. 1999. Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha. Nature 401:606-610.
21. Johnson KG, Van Vactor D. 2003. Receptor protein tyrosine phosphatases in nervous system development. Physiol Rev 83:1-24.
22. Johnson P, Ostergaard HL, Wasden C, Trowbridge IS. 1992. Mutational analysis of CD45. A leukocyte-specific protein tyrosine phosphatase. J Biol Chem 267:8035-8041.
23. Kokel M, Borland CZ, DeLong L, Horvitz HR, Stern MJ. 1998. clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans. Genes Dev 12:1425-1437.
24. Kolmodin K, Aqvist J. 2001. The catalytic mechanism of protein tyrosine phosphatases revisited. FEBS Lett 498: 208-213.
25. Krueger NX, Reddy RS, Johnson K, Bateman J, Kaufmann N, Scalice D, Van Vactor D, Saito H. 2003. Functions of the ectodomain and cytoplasmic tyrosine phosphatase domains of receptor protein tyrosine phosphatase Dlar in vivo. Mol Cell Biol 23:6909-6921.
26. Lohse DL, Denu JM, Santoro N, Dixon JE. 1997. Roles of aspartic acid-181 and serine-222 in intermediate formation and hydrolysis of the mammalian protein-tyrosine-phosphatase PTP1. Biochemistry 36:4568-4575.
27. Maurel-Zaffran C, Suzuki T, Gahmon G, Treisman JE, Dickson BJ. 2001. Cell-autonomous and -nonautonomous functions of LAR in R7 photoreceptor axon targeting. Neuron 32:225-235.
28. Montalibet J, Skorey KI, Kennedy BP. 2005. Protein tyrosine phosphatase: Enzymatic assays. Methods 35: 2-8.
29. Muise ES, Vrielink A, Ennis MA, Lemieux NH, Tremblay ML. 1996. Thermosensitive mutants of the MPTP and hPTP1B protein tyrosine phosphatases: Isolation and structural analysis. Protein Sci 5:604-613.
30. Newsome TP, Asling B, Dickson BJ. 2000. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development 127:851-860.
31. Petrone A, Sap J. 2000. Emerging issues in receptor protein tyrosine phosphatase function: Lifting fog or simply shifting? J Cell Sci 113(Pt 13):2345-2354.
32. Romsicki Y, Kennedy BP, Asante-Appiah E. 2003. Purification and characterization of T cell protein tyrosine phosphatase reveals significant functional homology to protein tyrosine phosphatase-1B. Arch Biochem Biophys 414:40-50.
33. Singh DK, Kumar D, Siddiqui Z, Basu SK, Kumar V, Rao KV. 2005. The strength of receptor signaling is centrally controlled through a cooperative loop between Ca2+ and an oxidant signal. Cell 121:281-293.
34. Stoker AW. 2001. Receptor tyrosine phosphatases in axon growth and guidance. Curr Opin Neurobiol 11:95-102.
35. Streuli M, Krueger NX, Thai T, Tang M, Saito H. 1990. Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR. Embo J 9:2399-2407.
36. Sun Q, Bahri S, Schmid A, Chia W, Zinn K. 2000a. Receptor tyrosine phosphatases regulate axon guidance across the midline of the Drosophila embryo. Development 127:801-812.
37. Sun QL, Wang J, Bookman RJ, Bixby JL. 2000b. Growth cone steering by receptor tyrosine phosphatase delta defines a distinct class of guidance cue. Mol Cell Neurosci 16:686-695.
38. Sun Q, Schindelholz B, Knirr M, Schmid A, Zinn K. 2001. Complex genetic interactions among four receptor tyrosine phosphatases regulate axon guidance in Drosophila. Mol Cell Neurosci 17:274-291.
39. Tonks NK. 2005. Redox redux: Revisiting PTPs and the control of cell signaling. Cell 121:667-670.
40. Welte S, Baringhaus KH, Schmider W, Muller G, Petry S, Tennagels N. 2005. 6,8-Difluoro-4-methylumbiliferyl phosphate: A fluorogenic substrate for protein tyrosine phosphatases. Anal Biochem 338:32-38.
41. Yang J, Niu T, Zhang A, Mishra AK, Zhao ZJ, Zhou GW. 2001. Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1. J Cell Biochem 84:47-55.
42. Zhang ZY, Clemens JC, Schubert HL, Stuckey JA, Fischer MW, Hume DM, Saper MA, Dixon JE. 1992. Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase. J Biol Chem 267:23759-23766.
43. Zhang ZY, Wang Y, Dixon JE. 1994. Dissecting the catalytic mechanism of protein-tyrosine phosphatases. Proc Natl Acad Sci USA 91:1624-1627.