A combined immuno-informatics and structure-based modeling approach for prediction of T cell epitopes of secretory proteins of Mycobacterium tuberculosis

Microbes and Infection

Volumn 8, Issue 3, 2006, Pages 738-746

  Vani, J ^a   Shaila, M S ^a   Chandra, N R ^a   Nayak, R ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

HLA class I binding; Mycobacterium tuberculosis; Secretory proteins; T cell epitopes; Vaccine design

Indexed keywords

ALANYLALANYLALANYLALANYLGLYCYLVALYLTHREONYLSERYLISOLEUCINE; ALANYLALANYLALANYLVALYLALANYLASPARTYLARGINYLASPARTYLVALINE; ALANYLALANYLLEUCYLGLYCYLLEUCYLGLYCYLISOLEUCYLLEUCYLLEUCINE; ALANYLARGINYLSERYLVALYLVALYLLEUCYLSERYLVALYLLEUCINE; ALANYLGLYCYLLEUCYLPROLYLISOLEUCYLPROLYLPROLYLISOLEUCYLISOLEUCINE; ALANYLPROLYLALANYLALANYLALANYLTHREONYLVALYLMETHIONYLVALINE; ALANYLVALYLPHENYLALANYLLEUCYLALANYLSERYLLEUCYLGLUTAMYLARGININE; ARGINYLARGINYLGLYCYLPROLYLLEUCYLGLUTAMINYLALANYLALANYLPHENYLALANINE; ASPARAGINYLARGINYLSERYLVALYLLEUCYLALANYLALANYLASPARTYLVALINE; BACTERIAL PROTEIN; EPITOPE; GLYCYLPHENYLALANYLLYSYLALANYLLEUCYLASPARTYLISOLEUCYLTHREONYLLEUCINE; HLA ANTIGEN CLASS 1; ISOLEUCYLALANYLTHREONYLALANYLVALYLLEUCYLVALYLALANYLVALINE; LEUCYLARGINYLCYSTEINYLVALYLALANYLALANYLLEUCYLALANYLARGININE; LEUCYLGLUTAMYLLEUCYLARGINYLGLUTAMYLLEUCYLALANYLASPARTYLLEUCINE; LEUCYLGLYCYLALANYLALANYLLEUCYLGLYCYLLEUCYLGLYCYLISOLEUCINE; METHIONYLALANYLARGINYLGLYCYLASPARTYLALANYLASPARAGINYLLYSYLVALINE; METHIONYLVALYLGLYCYLALANYLGLYCYLASPARTYLLEUCYLVALYLARGININE; SECRETORY PROTEIN; SERYLALANYLPROLYLALANYLTHREONYLVALYLPROLYLPROLYLVALINE; SERYLALANYLVALYLALANYLVALYLVALYLALANYLLEUCYLLEUCINE; SERYLARGINYLLEUCYLLEUCYLALANYLLEUCYLLEUCYLCYSTEINYLALANINE; SERYLPHENYLALANYLGLYCYLLEUCYLLEUCYLLEUCYLGLYCYLGLYCYLLEUCINE; THREONYLALANYLARGINYLSERYLVALYLVALYLLEUCYLSERYLVALINE; THREONYLMETHIONYLPHENYLALANYLVALYLALANYLLEUCYLLEUCYLGLYCYLLEUCINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALYLALANYLALANYLALANYLALANYLGLYCYLALANYLARGINYLLEUCINE; VALYLALANYLLEUCYLASPARTYLVALYLALANYLARGINYLISOLEUCYLLEUCINE; VALYLALANYLTHREONYLALANYLALANYLALANYLTHREONYLTHREONYLVALINE; BACTERIAL ANTIGEN;

ALGORITHM; ALLELE; AMINO TERMINAL SEQUENCE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DISSOCIATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR MODEL; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PEPTIDE ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEOMICS; SIGNAL TRANSDUCTION; T LYMPHOCYTE; AMINO ACID SEQUENCE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; IMMUNOLOGY; METABOLISM; PROTEIN CONFORMATION;

MYCOBACTERIUM TUBERCULOSIS;

AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; EPITOPES, T-LYMPHOCYTE; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 33746316816     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2005.09.012     Document Type: Article

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