-
1
-
-
0028859738
-
Onset and progression of pathological lesions in transforming growth factor-beta 1-deficient mice
-
Boivin GP, O'Toole BA, Orsmby IE, et al. Onset and progression of pathological lesions in transforming growth factor-beta 1-deficient mice. Am J Pathol 1995;146:276-288.
-
(1995)
Am J Pathol
, vol.146
, pp. 276-288
-
-
Boivin, G.P.1
O'Toole, B.A.2
Orsmby, I.E.3
-
2
-
-
0028982242
-
Transforming growth factor-beta 1 null mice. An animal model for inflammatory disorders
-
Kulkarni AB, Ward JM, Yaswen L, et al. Transforming growth factor-beta 1 null mice. An animal model for inflammatory disorders. Am J Pathol 1995;146:264-275.
-
(1995)
Am J Pathol
, vol.146
, pp. 264-275
-
-
Kulkarni, A.B.1
Ward, J.M.2
Yaswen, L.3
-
3
-
-
0035873731
-
Genetic regulation of autoimmune disease: BALB/c background TGF-beta 1-deficient mice develop necroinflammatory IFN-gamma-dependent hepatitis
-
Gorham JD, Lin JT, Sung JL, et al. Genetic regulation of autoimmune disease: BALB/c background TGF-beta 1-deficient mice develop necroinflammatory IFN-gamma-dependent hepatitis. J Immunol 2001;166:6413-6422.
-
(2001)
J Immunol
, vol.166
, pp. 6413-6422
-
-
Gorham, J.D.1
Lin, J.T.2
Sung, J.L.3
-
4
-
-
0029618694
-
Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated
-
USA
-
Diebold RJ, Eis MJ, Yin M, et al. Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated. Proc Natl Acad Sci USA 1995;92:12215-12219.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 12215-12219
-
-
Diebold, R.J.1
Eis, M.J.2
Yin, M.3
-
5
-
-
0242584864
-
Necroinflammatory liver disease in BALB/c background, TGF-beta1-deficient mice requires CD4(+) T cells
-
Rudner LA, Lin JT, Park IK, et al. Necroinflammatory liver disease in BALB/c background, TGF-beta1-deficient mice requires CD4(+) T cells. J Immunol 2003;170:4785-4792.
-
(2003)
J Immunol
, vol.170
, pp. 4785-4792
-
-
Rudner, L.A.1
Lin, J.T.2
Park, I.K.3
-
6
-
-
0029907123
-
Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression
-
Letterio JJ, Geiser AG, Kulkarni AB, et al. Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression. J Clin Invest 1996;98:2109-2119.
-
(1996)
J Clin Invest
, vol.98
, pp. 2109-2119
-
-
Letterio, J.J.1
Geiser, A.G.2
Kulkarni, A.B.3
-
7
-
-
0027241250
-
Effect of transforming growth factor-beta on early and late activation events in human T cells
-
Ahuja SS, Paliogianni F, Yamada H, et al. Effect of transforming growth factor-beta on early and late activation events in human T cells. J Immunol 1993;150(Part 1):3109-3118.
-
(1993)
J Immunol
, vol.150
, Issue.1 PART
, pp. 3109-3118
-
-
Ahuja, S.S.1
Paliogianni, F.2
Yamada, H.3
-
8
-
-
0027049404
-
Transforming growth factor-beta inhibits human T-cell proliferation through multiple targets
-
Fox FE, Capocasale RJ, Ford HC, et al. Transforming growth factor-beta inhibits human T-cell proliferation through multiple targets. Lymphokine Cytokine Res 1992;11:299-305.
-
(1992)
Lymphokine Cytokine Res
, vol.11
, pp. 299-305
-
-
Fox, F.E.1
Capocasale, R.J.2
Ford, H.C.3
-
9
-
-
1642317058
-
Smad3 is essential for TGF-beta 1 to suppress IL-2 production and TCR-induced proliferation, but not IL-2-induced proliferation
-
McKarns SC, Schwartz RH, Kaminski NE. Smad3 is essential for TGF-beta 1 to suppress IL-2 production and TCR-induced proliferation, but not IL-2-induced proliferation. J Immunol 2004;172:4275-4284.
-
(2004)
J Immunol
, vol.172
, pp. 4275-4284
-
-
McKarns, S.C.1
Schwartz, R.H.2
Kaminski, N.E.3
-
10
-
-
0035287455
-
TGF-beta abrogates TCR-mediated signaling by upregulating tyrosine phosphatases in T cells
-
Choudhry MA, Sir O, Sayeed MM. TGF-beta abrogates TCR-mediated signaling by upregulating tyrosine phosphatases in T cells. Shock 2001;15:193-199.
-
(2001)
Shock
, vol.15
, pp. 193-199
-
-
Choudhry, M.A.1
Sir, O.2
Sayeed, M.M.3
-
11
-
-
0037867066
-
Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation
-
Chen CH, Seguin-Devaux C, Burke NA, et al. Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation. J Exp Med 2003;197:1689-1699.
-
(2003)
J Exp Med
, vol.197
, pp. 1689-1699
-
-
Chen, C.H.1
Seguin-Devaux, C.2
Burke, N.A.3
-
12
-
-
0242584870
-
TGF-beta 1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes
-
Bommireddy R, Saxena V, Ormsby I, et al. TGF-beta 1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes. J Immunol 2003;170:4612-4622.
-
(2003)
J Immunol
, vol.170
, pp. 4612-4622
-
-
Bommireddy, R.1
Saxena, V.2
Ormsby, I.3
-
13
-
-
0037378732
-
TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes
-
Bommireddy R, Ormsby I, Yin M, et al. TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes. J Immunol 2003;170:3645-3652.
-
(2003)
J Immunol
, vol.170
, pp. 3645-3652
-
-
Bommireddy, R.1
Ormsby, I.2
Yin, M.3
-
14
-
-
0030775139
-
Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
-
Kirberg J, Berns A, von Boehmer H. Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules. J Exp Med 1997;186:1269-1275.
-
(1997)
J Exp Med
, vol.186
, pp. 1269-1275
-
-
Kirberg, J.1
Berns, A.2
Von Boehmer, H.3
-
15
-
-
0030727150
-
Survival of mature CD4T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells
-
Brocker T. Survival of mature CD4T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells. J Exp Med 1997;186:1223-1232.
-
(1997)
J Exp Med
, vol.186
, pp. 1223-1232
-
-
Brocker, T.1
-
16
-
-
0034305740
-
CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling
-
Dorfman JR, Stefanova I, Yasutomo K, et al. CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling. Nat Immunol 2000;1:329-335.
-
(2000)
Nat Immunol
, vol.1
, pp. 329-335
-
-
Dorfman, J.R.1
Stefanova, I.2
Yasutomo, K.3
-
17
-
-
0035902513
-
IL-7 is critical for homeostatic proliferation and survival of naive T cells
-
USA
-
Tan JT, Dudl E, LeRoy E, et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci USA 2001;98:8732-8737.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 8732-8737
-
-
Tan, J.T.1
Dudl, E.2
LeRoy, E.3
-
18
-
-
0036430221
-
TCR-independent proliferation and differentiation of human CD4+ T cell subsets induced by cytokines
-
Geginat J, Campagnaro S, Sallusto F, et al. TCR-independent proliferation and differentiation of human CD4+ T cell subsets induced by cytokines. Adv Exp Med Biol 2002;512:107-112.
-
(2002)
Adv Exp Med Biol
, vol.512
, pp. 107-112
-
-
Geginat, J.1
Campagnaro, S.2
Sallusto, F.3
-
19
-
-
0031981378
-
LFA-3 costimulates cytokine secretion by cytotoxic T lymphocytes by providing a TCR-independent activation signal
-
Le Guiner S, Le Drean E, Labarriere N, et al. LFA-3 costimulates cytokine secretion by cytotoxic T lymphocytes by providing a TCR-independent activation signal. Eur J Immunol 1998;28:1322-1331.
-
(1998)
Eur J Immunol
, vol.28
, pp. 1322-1331
-
-
Le Guiner, S.1
Le Drean, E.2
Labarriere, N.3
-
20
-
-
0031985899
-
Intercellular adhesion molecule-1 and leukocyte function-associated antigen-3 provide costimulation for superantigen-induced T lymphocyte proliferation in the absence of a specific presenting molecule
-
Lamphear JG, Stevens KR, Rich RR. Intercellular adhesion molecule-1 and leukocyte function-associated antigen-3 provide costimulation for superantigen-induced T lymphocyte proliferation in the absence of a specific presenting molecule. J Immunol 1998;160:615-623.
-
(1998)
J Immunol
, vol.160
, pp. 615-623
-
-
Lamphear, J.G.1
Stevens, K.R.2
Rich, R.R.3
-
21
-
-
0036789151
-
Cytokine-dependent bystander hepatitis due to intrahepatic murine CD8 T- Cell activation by bone marrow-derived cells
-
Bowen DG, Warren A, Davis T, et al. Cytokine-dependent bystander hepatitis due to intrahepatic murine CD8 T- cell activation by bone marrow-derived cells. Gastroenterology 2002;123:1252-1264.
-
(2002)
Gastroenterology
, vol.123
, pp. 1252-1264
-
-
Bowen, D.G.1
Warren, A.2
Davis, T.3
-
22
-
-
0035879109
-
Antigen presentation by liver cells controls intrahepatic T cell trapping, whereas bone marrow-derived cells preferentially promote intrahepatic T cell apoptosis
-
Mehal WZ, Azzaroli F, Crispe IN. Antigen presentation by liver cells controls intrahepatic T cell trapping, whereas bone marrow-derived cells preferentially promote intrahepatic T cell apoptosis. J Immunol 2001;167:667-673.
-
(2001)
J Immunol
, vol.167
, pp. 667-673
-
-
Mehal, W.Z.1
Azzaroli, F.2
Crispe, I.N.3
-
23
-
-
0027451442
-
Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice
-
Heath WR, Miller JF. Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice. J Exp Med 1993;178:1807-1811.
-
(1993)
J Exp Med
, vol.178
, pp. 1807-1811
-
-
Heath, W.R.1
Miller, J.F.2
-
24
-
-
0032763792
-
Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR
-
Saparov A, Kraus LA, Cong Y, et al. Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR. Int Immunol 1999;11:1253-1264.
-
(1999)
Int Immunol
, vol.11
, pp. 1253-1264
-
-
Saparov, A.1
Kraus, L.A.2
Cong, Y.3
-
25
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
-
Shull MM, Ormsby I, Kier AB, et al. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 1992;359:693-699.
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
Ormsby, I.2
Kier, A.B.3
-
26
-
-
20844462744
-
Animal models of autoimmune diseases of the liver
-
Gershwin ME, Vierling JM, Manns MP (eds). Hanley & Belfus, Inc.: Philadelphia
-
Vierling JM. Animal models of autoimmune diseases of the liver. In: Gershwin ME, Vierling JM, Manns MP (eds). Liver Immunology. Hanley & Belfus, Inc.: Philadelphia, 2003, pp 263-290.
-
(2003)
Liver Immunology
, pp. 263-290
-
-
Vierling, J.M.1
-
27
-
-
0029037740
-
Expression of two T cell receptor alpha chains on the surface of normal murine T cells
-
Heath WR, Carbone FR, Bertolino P, et al. Expression of two T cell receptor alpha chains on the surface of normal murine T cells. Eur J Immunol 1995;25:1617-1623.
-
(1995)
Eur J Immunol
, vol.25
, pp. 1617-1623
-
-
Heath, W.R.1
Carbone, F.R.2
Bertolino, P.3
-
28
-
-
0027422750
-
Expression of two T cell receptor alpha chains: Dual receptor T cells
-
Padovan E, Casorati G, Dellabona P, et al. Expression of two T cell receptor alpha chains: dual receptor T cells. Science 1993;262:422-424.
-
(1993)
Science
, vol.262
, pp. 422-424
-
-
Padovan, E.1
Casorati, G.2
Dellabona, P.3
-
29
-
-
0028171175
-
Cellular expression of tumour necrosis factor-alpha and interferon-gamma in the liver biopsies of children with chronic liver disease
-
Hussain MJ, Mustafa A, Gallati H, et al. Cellular expression of tumour necrosis factor-alpha and interferon-gamma in the liver biopsies of children with chronic liver disease. J Hepatol 1994;21:816-821.
-
(1994)
J Hepatol
, vol.21
, pp. 816-821
-
-
Hussain, M.J.1
Mustafa, A.2
Gallati, H.3
-
30
-
-
0028221369
-
Phenotypical analysis and cytokine release of liver-infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiology
-
Lohr HF, Schlaak JF, Gerken G, et al. Phenotypical analysis and cytokine release of liver-infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiology. Liver 1994;14:161-166.
-
(1994)
Liver
, vol.14
, pp. 161-166
-
-
Lohr, H.F.1
Schlaak, J.F.2
Gerken, G.3
-
31
-
-
18744416828
-
Autoantibodies and autoantigens in autoimmune hepatitis
-
Strassburg CP, Manns MP. Autoantibodies and autoantigens in autoimmune hepatitis. Semin Liver Dis 2002;22:339-352.
-
(2002)
Semin Liver Dis
, vol.22
, pp. 339-352
-
-
Strassburg, C.P.1
Manns, M.P.2
-
32
-
-
0023813850
-
Antiliver kidney microsome antibody recognizes a cytochrome P450 from the IID subfamily
-
Gueguen M, Meunier-Rotival M, Bernard O, et al. Antiliver kidney microsome antibody recognizes a cytochrome P450 from the IID subfamily. J Exp Med 1988;168:801-806.
-
(1988)
J Exp Med
, vol.168
, pp. 801-806
-
-
Gueguen, M.1
Meunier-Rotival, M.2
Bernard, O.3
-
33
-
-
0033048427
-
Formiminotransferase cyclodeaminase is an organ-specific autoantigen recognized by sera of patients with autoimmune hepatitis
-
Lapierre P, Hajoui O, Homberg JC, et al. Formiminotransferase cyclodeaminase is an organ-specific autoantigen recognized by sera of patients with autoimmune hepatitis. Gastroenterology 1999;116:643-649.
-
(1999)
Gastroenterology
, vol.116
, pp. 643-649
-
-
Lapierre, P.1
Hajoui, O.2
Homberg, J.C.3
-
34
-
-
0035053878
-
The lymphoid liver: Considerations on pathways to autoimmune injury
-
Kita H, Mackay IR, Van De Water J, et al. The lymphoid liver: considerations on pathways to autoimmune injury. Gastroenterology 2001;120:1485-1501.
-
(2001)
Gastroenterology
, vol.120
, pp. 1485-1501
-
-
Kita, H.1
Mackay, I.R.2
Van De Water, J.3
-
35
-
-
0031888390
-
Limited T cell receptor Vbeta-chain repertoire of liver-infiltrating T cells in autoimmune hepatitis
-
Arenz M, Meyer zum Buschenfelde KH, Lohr HF. Limited T cell receptor Vbeta-chain repertoire of liver-infiltrating T cells in autoimmune hepatitis. J Hepatol 1998;28:70-77.
-
(1998)
J Hepatol
, vol.28
, pp. 70-77
-
-
Arenz, M.1
Meyer Zum Buschenfelde, K.H.2
Lohr, H.F.3
-
36
-
-
0030917311
-
Clonotypic analysis of T cells in patients with autoimmune and viral hepatitis
-
Tanaka A, Iwabuchi S, Takatori M, et al. Clonotypic analysis of T cells in patients with autoimmune and viral hepatitis. Hepatology 1997;25:1070-1076.
-
(1997)
Hepatology
, vol.25
, pp. 1070-1076
-
-
Tanaka, A.1
Iwabuchi, S.2
Takatori, M.3
-
37
-
-
0029113724
-
Limited usage of T-cell receptor beta chains and sequences of the complementarity determining region 3 of lymphocytes infiltrating in the liver of autoimmune hepatitis
-
Hoshino Y, Enomoto N, Izumi N, et al. Limited usage of T-cell receptor beta chains and sequences of the complementarity determining region 3 of lymphocytes infiltrating in the liver of autoimmune hepatitis. Hepatology 1995;22:142-147.
-
(1995)
Hepatology
, vol.22
, pp. 142-147
-
-
Hoshino, Y.1
Enomoto, N.2
Izumi, N.3
-
38
-
-
0031150005
-
Germ-free and barrier-raised TGF beta 1-deficient mice have similar inflammatory lesions
-
Boivin GP, Ormsby I, Jones-Carson J, et al. Germ-free and barrier-raised TGF beta 1-deficient mice have similar inflammatory lesions. Transgenic Res 1997;6:197-202.
-
(1997)
Transgenic Res
, vol.6
, pp. 197-202
-
-
Boivin, G.P.1
Ormsby, I.2
Jones-Carson, J.3
-
39
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack B, Merz H, Schorle H, et al. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993;75:253-261.
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
-
40
-
-
0034014016
-
Spontaneous chronic colitis in TCR alpha-mutant mice; an experimental model of human ulcerative colitis
-
Bhan AK, Mizoguchi E, Smith RN, et al. Spontaneous chronic colitis in TCR alpha-mutant mice; an experimental model of human ulcerative colitis. Int Rev Immunol 2000;19:123-138.
-
(2000)
Int Rev Immunol
, vol.19
, pp. 123-138
-
-
Bhan, A.K.1
Mizoguchi, E.2
Smith, R.N.3
-
41
-
-
0032079771
-
Transforming growth factor-beta1 in autoimmune hepatitis: Correlation of liver tissue expression and serum levels with disease activity
-
Bayer EM, Herr W, Kanzler S, et al. Transforming growth factor-beta1 in autoimmune hepatitis: correlation of liver tissue expression and serum levels with disease activity. J Hepatol 1998;28:803-811.
-
(1998)
J Hepatol
, vol.28
, pp. 803-811
-
-
Bayer, E.M.1
Herr, W.2
Kanzler, S.3
-
42
-
-
6344288772
-
Serum level of transforming growth factor-beta1 (TGF-beta1) and the expression of TGF-beta receptor type II in peripheral blood mononuclear cells in patients with autoimmune hepatitis
-
Sakaguchi K, Kitano M, Nishimura M, et al. Serum level of transforming growth factor-beta1 (TGF-beta1) and the expression of TGF-beta receptor type II in peripheral blood mononuclear cells in patients with autoimmune hepatitis. Hepatogastroenterology 2004;51:1780-1783.
-
(2004)
Hepatogastroenterology
, vol.51
, pp. 1780-1783
-
-
Sakaguchi, K.1
Kitano, M.2
Nishimura, M.3
-
43
-
-
0037370898
-
Impairment of TGF-beta signaling in T cells increases susceptibility to experimental autoimmune hepatitis in mice
-
Schramm C, Protschka M, Kohler HH, et al. Impairment of TGF-beta signaling in T cells increases susceptibility to experimental autoimmune hepatitis in mice. Am J Physiol Gastrointest Liver Physiol 2003;284:G525-G535.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Schramm, C.1
Protschka, M.2
Kohler, H.H.3
-
44
-
-
31944433741
-
TGF-beta/Smad signaling in the injured liver
-
Breitkopf K, Godoy P, Ciuclan L, et al. TGF-beta/Smad signaling in the injured liver. Z Gastroenterol 2006;44:57-66.
-
(2006)
Z Gastroenterol
, vol.44
, pp. 57-66
-
-
Breitkopf, K.1
Godoy, P.2
Ciuclan, L.3
|