메뉴 건너뛰기




Volumn 20, Issue 3, 2006, Pages 243-247

Benzalkonium chloride and nasal mucociliary clearance: A randomized, placebo-controlled, crossover, double-blind trial

Author keywords

[No Author keywords available]

Indexed keywords

BENZALKONIUM CHLORIDE; NOSE SPRAY; PLACEBO; SALSEP; SODIUM CHLORIDE; SORINE INFANTIL; STRONTIUM; TECHNETIUM 99M;

EID: 33746177513     PISSN: 10506586     EISSN: None     Source Type: Journal    
DOI: 10.2500/ajr.2006.20.2867     Document Type: Article
Times cited : (14)

References (20)
  • 2
    • 33746154723 scopus 로고    scopus 로고
    • Is the use of benzalkonium chloride as a preservative for nasal formulations a safety concern? A cautionary note based on compromised mucociliary transport
    • Bernstein IL. Is the use of benzalkonium chloride as a preservative for nasal formulations a safety concern? A cautionary note based on compromised mucociliary transport. J Allergy Clin Immunol 106:595-596, 2000.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 595-596
    • Bernstein, I.L.1
  • 3
    • 0034816943 scopus 로고    scopus 로고
    • Benzalconium chloride as a preservative in nasal solutions: Re-examining the data
    • Graf P. Benzalconium chloride as a preservative in nasal solutions: Re-examining the data. Respir Med 95:728-733, 2001.
    • (2001) Respir Med , vol.95 , pp. 728-733
    • Graf, P.1
  • 4
    • 0035857966 scopus 로고    scopus 로고
    • The CONSORT statement: Revised recommendations for improving the quality of reports of parallel-group randomises trials
    • Moher D, Schulz KF, and Altman DG. The CONSORT statement: Revised recommendations for improving the quality of reports of parallel-group randomises trials. Lancet 357: 1191-1194, 2001.
    • (2001) Lancet , vol.357 , pp. 1191-1194
    • Moher, D.1    Schulz, K.F.2    Altman, D.G.3
  • 5
    • 0242670720 scopus 로고    scopus 로고
    • Sample size
    • (Eds.). 3rd ed. St. Louis, MO: Mosby-Year Book, Inc
    • Friedman LM, Furberg CD, and DeMets DL (Eds.). Sample size. In Clinical Trials, 3rd ed. St. Louis, MO: Mosby-Year Book, Inc., 94-129, 1996.
    • (1996) Clinical Trials , pp. 94-129
    • Friedman, L.M.1    Furberg, C.D.2    DeMets, D.L.3
  • 6
    • 0027957482 scopus 로고
    • Nasal and otologic effects of experimental influenza A virus infection
    • Doyle WJ, Skoner DP, Hayden F, et al. Nasal and otologic effects of experimental influenza A virus infection. Ann Otol Rhinol Laryngol 103:59-69, 1994.
    • (1994) Ann Otol Rhinol Laryngol , vol.103 , pp. 59-69
    • Doyle, W.J.1    Skoner, D.P.2    Hayden, F.3
  • 7
    • 0001982317 scopus 로고
    • Crossover trials
    • (Ed). Chichester, England: Wiley & Sons, Ltd
    • Pocock SJ (Ed). Crossover trials. In Clinical Trials. A Practical Approach. Chichester, England: Wiley & Sons, Ltd., 110-122, 1983.
    • (1983) Clinical Trials. A Practical Approach , pp. 110-122
    • Pocock, S.J.1
  • 8
    • 0031687745 scopus 로고    scopus 로고
    • Mucociliary transport and its assessment: A review
    • Lale AM, Mason JDT, and Jones NS. Mucociliary transport and its assessment: A review. Clin Otolaryngol 23:388-396, 1998.
    • (1998) Clin Otolaryngol , vol.23 , pp. 388-396
    • Lale, A.M.1    Mason, J.D.T.2    Jones, N.S.3
  • 9
    • 0037294227 scopus 로고    scopus 로고
    • A comparison of nasal clearance after treatment of perennial allergic rhinitis with budesonide and mometasone
    • Naclerio RM, Baroody FM, Bidani N, et al. A comparison of nasal clearance after treatment of perennial allergic rhinitis with budesonide and mometasone. Otolaryngol Head Neck Surg 128:220-227, 2003.
    • (2003) Otolaryngol Head Neck Surg , vol.128 , pp. 220-227
    • Naclerio, R.M.1    Baroody, F.M.2    Bidani, N.3
  • 10
    • 1642495605 scopus 로고    scopus 로고
    • Safety Review of benzalkonium chloride used as preservative in intranasal solutions: An overview of conflicting data and opinions
    • Marple B, Roland P, and Benninger M. Safety Review of benzalkonium chloride used as preservative in intranasal solutions: An overview of conflicting data and opinions. Otolaryngol Head Neck Surg 130:131-141, 2004.
    • (2004) Otolaryngol Head Neck Surg , vol.130 , pp. 131-141
    • Marple, B.1    Roland, P.2    Benninger, M.3
  • 11
    • 0029067318 scopus 로고
    • Benzalkonium chloride in a decongestant nasal spray aggravates rhinitis medicamentosa in healthy volunteers
    • Graf P, Hallen H, and Juto JE. Benzalkonium chloride in a decongestant nasal spray aggravates rhinitis medicamentosa in healthy volunteers. Clin Exp Allergy 25:395-400, 1995.
    • (1995) Clin Exp Allergy , vol.25 , pp. 395-400
    • Graf, P.1    Hallen, H.2    Juto, J.E.3
  • 12
    • 0029919277 scopus 로고    scopus 로고
    • Effect on the nasal mucosa of long-term treatment with oxymetazoline, benzalkonium chloride, and placebo nasal sprays
    • Graf P, and Hallen H. Effect on the nasal mucosa of long-term treatment with oxymetazoline, benzalkonium chloride, and placebo nasal sprays. Laryngoscope 106:605-609, 1996.
    • (1996) Laryngoscope , vol.106 , pp. 605-609
    • Graf, P.1    Hallen, H.2
  • 13
    • 4444308194 scopus 로고    scopus 로고
    • Effects of preservatives in nasal formulations on the mucosal integrity: An electron microscopic study
    • Lebe E, Baka M, Yavasoglu A, et al. Effects of preservatives in nasal formulations on the mucosal integrity: An electron microscopic study. Pharmacology 72:113-120, 2004.
    • (2004) Pharmacology , vol.72 , pp. 113-120
    • Lebe, E.1    Baka, M.2    Yavasoglu, A.3
  • 15
    • 1842582620 scopus 로고    scopus 로고
    • Influence of preservatives and topical steroids on ciliary beat frequency in vitro
    • Hofmann T, Gugatschga M, Koidl B, et al. Influence of preservatives and topical steroids on ciliary beat frequency in vitro. Arch Otolaryngol Head Neck Surg 130:440-445, 2004.
    • (2004) Arch Otolaryngol Head Neck Surg , vol.130 , pp. 440-445
    • Hofmann, T.1    Gugatschga, M.2    Koidl, B.3
  • 16
    • 0032850758 scopus 로고    scopus 로고
    • Ten days' use of oxymetazoline nasal spray with or without benzalkonium chloride in patients with vasomotor rhinitis
    • Graf P, Enerdal J, and Hallen H. Ten days' use of oxymetazoline nasal spray with or without benzalkonium chloride in patients with vasomotor rhinitis. Arch Otolaryngol Head Neck Surg 125:1128-1132, 1999.
    • (1999) Arch Otolaryngol Head Neck Surg , vol.125 , pp. 1128-1132
    • Graf, P.1    Enerdal, J.2    Hallen, H.3
  • 17
    • 0032745765 scopus 로고    scopus 로고
    • Adverse effects of benzalkonium chloride on the nasal mucosa: Allergic rhinitis and rhinitis medicamentosa
    • Graf P. Adverse effects of benzalkonium chloride on the nasal mucosa: Allergic rhinitis and rhinitis medicamentosa. Clin Ther 21:1749-1755, 1999.
    • (1999) Clin Ther , vol.21 , pp. 1749-1755
    • Graf, P.1
  • 19
    • 0031789238 scopus 로고    scopus 로고
    • Epidemiology of drug use during the first three months of life in a urban area of southern Brazil
    • Weiderpass E, Beria JU, Barros FC, et al. Epidemiology of drug use during the first three months of life in a urban area of southern Brazil. Rev Saude Publica 32:335-344, 1998.
    • (1998) Rev Saude Publica , vol.32 , pp. 335-344
    • Weiderpass, E.1    Beria, J.U.2    Barros, F.C.3
  • 20
    • 0345293241 scopus 로고    scopus 로고
    • The tolerability of nasal drugs with special regard to preservatives and physicochemical parameter
    • Verse T, Sikora C, Rudolph P, et al. The tolerability of nasal drugs with special regard to preservatives and physicochemical parameter. Laryngorhinootologie 82:782-789, 2003.
    • (2003) Laryngorhinootologie , vol.82 , pp. 782-789
    • Verse, T.1    Sikora, C.2    Rudolph, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.