Effects of preservatives in nasal formulations on the mucosal integrity: An electron microscopic study

Pharmacology

Volumn 72, Issue 2, 2004, Pages 113-120

  Lebe, Erkan ^a   Baka, Meral ^b,c   Yavaşoǧlu, Altuǧ ^b   Aktuǧ, Hüseyin ^b   Ateş, Utku ^b   Uyanikgil, Yiǧit ^b  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b EGE UNIVERSITY   (Turkey)

^c EGE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Benzalkonium chloride; Electron microscopy, nasal mucosa; Potassium sorbate; Preservatives, nasal mucosa effects

Indexed keywords

BENZALKONIUM CHLORIDE; NOSE DROPS; PRESERVATIVE; SORBATE POTASSIUM;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; HISTOLOGY; MALE; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; RAT; RESPIRATORY TRACT DISEASE; SAMPLING; SNEEZING; SYMPTOM;

ADMINISTRATION, INTRANASAL; ANIMALS; BENZALKONIUM COMPOUNDS; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NASAL MUCOSA; PRESERVATIVES, PHARMACEUTICAL; RATS; RATS, WISTAR; SORBIC ACID;

EID: 4444308194     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000080183     Document Type: Article

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