Novel fibrinogen receptor antagonists - RGDF mimetics, 4-(1,2,3,4-tetrahydro-isoquinoline-7-yl)amino-4-oxo-butyric acid derivatives

Medicinal Chemistry

Volumn 2, Issue 3, 2006, Pages 295-298

  Krysko, Andrei A ^a   Malovichko, Olga L ^a   Andronati, Sergei A ^a   Kabanova, Tatyana A ^a   Karaseva, Tamara L ^a   Petrus, Anna S ^a  

^a A V BOGATSKY PHYSICO CHEMICAL INSTITUTE   (Ukraine)

Author keywords

IIb 3; 1,2,3,4 tetrahydro isoquinoline; Fibrinogen receptor antagonists; GP IIb IIIa; Platelet aggregation; RGD mimetics

Indexed keywords

4 (1,2,3,4 TETRAHYDROISOQUINOLINE 7 YL)AMINO 4 OXOBUTYRIC ACID DERIVATIVE; 4 (1,2,3,4 TETRAHYDROISOQUINOLINE 7 YL)AMINO 4 OXOBUTYRYL BETA ALANINE HYDROCHLORIDE; 4 (1,2,3,4 TETRAHYDROISOQUINOLINE 7 YL)AMINO 4 OXOBUTYRYL DEXTRO LEVO BETA PHENYL BETA ALANINE HYDROCHLORIDE; 4 (ISOINDOLE 5 YL)AMINO 4 OXOBUTYRIC ACID; ARGININE; ARGINYLGLYCYLASPARTYLPHENYLALANINE; BUTYRIC ACID DERIVATIVE; FIBRINOGEN; FIBRINOGEN RECEPTOR ANTAGONIST; FLUORESCEIN ISOTHIOCYANATE; GLYCINE; TETRAPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN MOTIF; THROMBOCYTE AGGREGATION INHIBITION;

ISOQUINOLINES; MAGNETIC RESONANCE SPECTROSCOPY; RECEPTORS, FIBRINOGEN; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT;

EID: 33746125331     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340606776930817     Document Type: Article

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