Tyr-48, a conserved residue in ribotoxins, is involved in the RNA-degrading activity of α-sarcin

Biological Chemistry

Volumn 387, Issue 5, 2006, Pages 535-541

  Álvarez García, Elisa ^a   García Ortega, Lucía ^a   Verdún, Yolanda ^b   Bruix, Marta ^b   Del Pozo, Álvaro Martínez ^a   Gavilanes, José G ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

Author keywords

sarcin; Catalytic tyrosine; Ribonuclease; RNase T1

Indexed keywords

ALPHA SARCIN; DINUCLEOSIDE PHOSPHATE; PHENOL; RIBONUCLEASE; RIBOTOXIN; TOXIN; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME MECHANISM; ESCHERICHIA COLI; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; RNA CLEAVAGE; RNA DEGRADATION;

CIRCULAR DICHROISM; ENDORIBONUCLEASES; FUNGAL PROTEINS; MAGNETIC RESONANCE SPECTROSCOPY; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PHENYLALANINE; PHOSPHATIDYLGLYCEROLS; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; RNA, FUNGAL; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE;

EID: 33746098873     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2006.069     Document Type: Article

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