Ribotoxins are a more widespread group of proteins within the filamentous fungi than previously believed

Toxicon

Volumn 37, Issue 11, 1999, Pages 1549-1563

  Martínez Ruiz, Antonio ^a   Kao, Richard ^b   Davies, Julian ^b   Martínez del Pozo, Álvaro ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SARCIN; MITOGILLIN; MYCOTOXIN; PROTEIN; RESTRICTOCIN; RIBONUCLEASE;

ARTICLE; ASPERGILLUS; DNA SEQUENCE; FUNGUS; GENE SEQUENCE; NONHUMAN; PENICILLIUM; PHYLOGENY; PRIORITY JOURNAL; TOXIN ANALYSIS;

ALLERGENS; AMINO ACID SEQUENCE; ANTIBIOTICS, ANTINEOPLASTIC; ASPERGILLUS; BASE SEQUENCE; BLOTTING, SOUTHERN; DNA, FUNGAL; ENDORIBONUCLEASES; FUNGAL PROTEINS; FUNGI; MOLECULAR SEQUENCE DATA; PENICILLIUM; PHYLOGENY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASES; RIBOSOMES; SPORES, FUNGAL;

FUNGI;

EID: 0033231653     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(99)00103-8     Document Type: Article

References (51)

1. Arruda L.K., Platts-Mills T.A.E., Fox J.W., Chapman M.D. Aspergillus fumigatus allergen I, a major IgE-binding protein, is a member of the mitogillin family of cytotoxins. J. Exp. Med. 172:1990;1529-1532.
2. Benner S.A., Ciglic M.I., Haugg M., Jermann T.M., Opitz J.G., Raillard-Yoon S.-A., Soucek J., Stackhouse J., Trabesinger-Rüf N., Trautwein K., Zankel T.R. Evolutionary reconstructions in the ribonuclease family. D'Alessio G., Riordan J.F. Ribonucleases: Structures and Functions. 1997;213-243 Academic Press, San Diego.
3. Bezborodova S.I., Khovoda O.M., Stepanov V.M. The complete amino acid sequence of ribonuclease C2 from Aspergillus clavatus. FEBS Lett. 159:1983;256-258.
4. Brandhorst T.T., Kenealy W.R. Production and localization of restrictocin in Aspergillus restrictus. J. Gen. Microbiol. 138:1992;1429-1435.
5. Brandhorst T., Dowd P.F., Kenealy W.R. The ribosome-inactivating protein restrictocin deters insect feeding on Aspergillus restrictus. Microbiology. 142:1996;1551-1556.
6. 15N nuclear magnetic resonance assignment and secondary structure of the cytotoxic ribonuclease α-sarcin. Protein Science. 5:1996;962-972.
7. Campos-Olivas R., Bruix M., Santoro J., Martínez del Pozo A., Lacadena J., Gavilanes J.G., Rico M. Structural basis for the catalytic mechanism and substrate specificity of the ribonuclease α-sarcin. FEBS Lett. 399:1996;163-165.
8. Ciglic M.I., Jackson P.J., Raillard S.A., Haugg M., Jermann T.M., Opitz J.G., Trabesinger-Rüf N., Benner S.A. Origin of dimeric structure in the ribonuclease superfamily. Biochemistry. 37:1998;4008-4022.
9. D'Alessio G., Di Donato A., Parente A., Piccoli R. Seminal RNase: a unique member of the ribonuclease superfamily. Tr. Biochem. Sci. 16:1991;104-106.
10. Don R.H., Cox P.T., Wainwright B.J., Baker K., Mattick J.S. "Touchdown" PCR to circumvent spurious priming during gene amplification. Nucl. Acids Res. 19:1991;4008.
11. Fernández-Luna J.L., López-Otín C., Soriano F., Méndez E. Complete amino acid sequence of the Aspergillus cytotoxin mitogillin. Biochemistry. 24:1985;861-867.
12. Fernández-Puentes C. Permeability to alpha-sarcin in virus-infected cells. Mol. Cell. Biochem. 50:1983;185-191.
13. Fernández-Puentes C., Carrasco L. Viral infection permeabilizes mammalian cells to protein toxins. Cell. 20:1980;769-775.
14. Gasset M., Martínez del Pozo A., Oñaderra M., Gavilanes J.G. Study of the interaction between the antitumour protein α-sarcin and phospholipid vesicles. Biochem. J. 258:1989;569-575.
15. Gasset M., Oñaderra M., Thomas P.G., Gavilanes J.G. Fusion of phospholipid vesicles produced by the anti-tumour protein α-sarcin. Biochem. J. 265:1990;815-822.
16. Gasset M., Oñaderra M., Martínez del Pozo A., Schiavo G.-P., Laynez J., Usobiaga P., Gavilanes J.G. Effect of the antitumour protein α-sarcin on the thermotropic behaviour of acid phospholipid vesicles. Biochim. Biophys. Acta. 1068:1991;9-16.
17. Gasset M., Oñaderra M., Goormaghtigh E., Gavilanes J.G. Acid phospholipid vesicles produce conformational changes on the antitumor protein α-sarcin. Biochim. Biophys. Acta. 1080:1991;51-58.
18. Huang K.-C., Hwang Y.-Y., Hwu L., Lin A. Characterization of a new ribotoxin gene (c-sar) from Aspergillus clavatus. Toxicon. 35:1997;383-392.
19. Kao R., Davies J. Fungal ribotoxins: a familiy of naturally engineered targeted toxins. Biochem. Cell Biol. 73:1995;1151-1159.
20. Kurup V.P., Kumar A., Kenealy W.R., Greenberger P.A. Aspergillus ribotoxins react with IgE and IgG antibodies of patients with allergic bronchopulmonary aspergillosis. J. Lab. Clin. Med. 123:1994;749-756.
21. Lacadena J., Martínez del Pozo A., Barbero J.L., Mancheño J.M., Gasset M., Oñaderra M., López-Otín C., Ortega S., García J.L., Gavilanes J.G. Overproduction and purification of biologically active native fungal alpha-sarcin in Escherichia coli. Gene. 142:1994;147-151.
22. Lacadena J., Martínez del Pozo A., Lacadena V., Martínez-Ruiz A., Mancheño J.M., Oñaderra M., Gavilanes J.G. The cytotoxin α-sarcin behaves as a cyclizing ribonuclease. FEBS Lett. 424:1998;46-48.
23. Lamy B., Davies J. Isolation and nucleotide sequence of the Aspergillus restrictus gene coding for the ribonucleolytic toxin restrictocin and its expression in Aspergillus nidulans: the leader sequence protects producing strains from suicide. Nucl. Acids Res. 19:1991;1001-1006.
24. Lamy B., Mouataouakil M., Latgé J.P., Davies J. Secretion of a potential virulence factor, a fungal ribonucleotoxin, during human aspergillosis infections. Mol. Microbiol. 5:1991;1811-1815.
25. Lamy B., Davies J., Schindler D. The Aspergillus ribonuclelytic toxins (ribotoxins). Frankel A.E. Genetically engineered toxins. 1992;237-258 Marcel Dekker, New York.
26. Lin A., Huang K.-C., Hwu L., Tzean S.S. Production of type II ribotoxins by Aspergillus species and related fungi in Taiwan. Toxicon. 33:1995;105-110.
27. Lin, A., Ciou-Jau, C., Tzean, S.S., 1997. EMBL/GenBank/DDBJ databases, accesion numbers AF012812-AF012817.
28. López-Otín C., Barber D., Fernández-Luna J.L., Soriano F., Méndez E. The primary structure of the cytotoxic restrictocin. Eur. J. Biochem. 143:1984;621-634.
29. Mancheño J.M., Gasset M., Lacadena J., Ramón F., Martínez del Pozo A., Oñaderra M., Gavilanes J.G. Kinetic study of the aggregation and lipid-mixing produced by α-sarcin on phosphatidylglycerol and phosphatidylserine vesicles: stopped-flow light-scattering and fluorescence energy transfer measurements. Biophys. J. 67:1994;1117-1125.
30. Miller S.P., Bodley J.W. The ribosomes of Aspergillus giganteus are sensitive to the cytotoxic action of α-sarcin. FEBS Lett. 229:1988;388-390.
31. Oka T., Aoyama Y., Natori Y., Katano T., Endo Y. The complete nucleotide sequence of cDNA for the cytotoxin alpha-sarcin. Nucl. Acids Res. 18:1990;1897.
32. Olmo N., Turnay J., Lizarbe M.A., Gavilanes J.G. Cytotoxic effects of α-sarcin, a ribosome inactivating protein, in cultured Rugli cells. S.T.P. Pharma Sci. 3:1993;93-96.
33. Olson B.H., Goerner G.L. Alpha-sarcin, a new antitumor agent, I. Isolation, purification, chemical composition, and the identity of a new amino acid. Appl. Microbiol. 13:1965;314-321.
34. Olson B.H., Jennings J.C., Roga V., Junek A.J., Schuurmans D.M. Alpha-sarcin, a new antitumor agent, II. Fermentation and antitumor spectrum. Appl. Microbiol. 13:1965;322-326.
35. Oñaderra M., Mancheño J.M., Gasset M., Lacadena J., Schiavo G., Martínez del Pozo A., Gavilanes J.G. Translocation of α-sarcin across the lipid bilayer of asolectin vesicles. Biochem. J. 295:1993;221-225.
36. Oñaderra M., Mancheño J.M., Lacadena J., de los Ríos V., Martínez del Pozo A., Gavilanes J.G. Oligomerization of the cytotoxin α-sarcin associated to phospholipid membranes. Mol. Memb. Biol. 15:1998;141-144.
37. Opitz J.G., Ciglic M.I., Haugg M., Trautwein-Fritz K., Raillard S.A., Jermann T.A., Benner S.A. Origin of the catalytic activity of bovine seminal ribonuclease against double-stranded DNA. Biochemistry. 37:1998;4023-4033.
38. Parente D., Raucci G., Celano B., Pacilli A., Zanoni L., Canevari S., Adorate E., Colnaghe M.I., Dosio F., Arpicco S., Catell L., Mele A., De Santis R. Clavin, a type-I ribosome-inactivating protein from Aspergillus clavatus IFO 8605. Eur. J. Biochem. 239:1996;272-280.
39. Paris S., Monod M., Diaquin M., Lamy B., Arruda L.K., Punt P.J., Latgé J.P. A transformant of Aspergillus fumigatus deficient in the antigenic cytotoxin ASPFI. FEMS Microbiol. Lett. 111:1993;31-36.
40. Raper T.B., Fennel D.I. The genus Aspergillus. 1965;Williams and Wilkins, Baltimore.
41. Roux K.H., Hecker K.H. One-step optimization using touchdown and stepdown PCR. Methods Mol. Biol. 67:1997;39-45.
42. Sacco G., Drickamer K., Wool I.G. The primary structure of the cytotoxin alpha-sarcin. J. Biol. Chem. 258:1983;5811-5818.
43. Schindler D., Davies J. Specific cleavage of ribosomal RNA caused by alpha-sarcin. Nucleic Acid Res. 4:1977;1097-1100.
44. Shapiro R., Riordan J.F., Vallee B.L. Characteristic ribonucleolytic activity of human angiogenin. Biochemistry. 25:1986;3527-3532.
45. Smith J.M., Davies J.E., Holden D.W. Construction and pathogenicity of Aspergillus fumigatus mutants that do not produce the ribotoxin restrictocin. Mol. Microbiol. 9:1993;1071-1077.
46. Smith J.M., Tang C.M., van Noorden S., Holden D.W. Virulence of Aspergillus fumigatus double mutants lacking restrictocin and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis. Infect. Immun. 62:1994;5247-5254.
47. St. Clair D.K.S., Rybak S.M., Riordan J.F., Vallee B.L. Angiogenin abolishes cell-free protein synthesis by specific ribonucleolytic inactivation of 40S ribosomes. Biochemistry. 27:1988;7263-7268.
48. Turnay J., Olmo N., Jiménez J., Lizarbe M.A., Gavilanes J.G. Kinetic study of the cytotoxic effect of α-sarcin, a ribosome inactivating protein from A. giganteus, on tumor cell lines: protein biosynthesis inhibition and cell binding. Mol. Cell. Biochem. 122:1993;39-47.
49. Wirth J., Martínez del Pozo A., Mancheño J.M., Martínez-Ruiz A., Lacadena J., Oñaderra M., Gavilanes J.G. Sequence determination and molecular characterization of gigantin, a cytotoxic protein produced by the mould Aspergillus giganteus IFO 5818. Arch. Biochem. Biophys. 343:1997;188-193.
50. Yang R., Kenealy W.R. Regulation of restrictocin production in Aspergillus restrictus. J. Gen. Microbiol. 138:1992;1421-1427.
51. Yang X., Moffat K. Insights into specificity of cleavage and mechanism of cell entry from the crystal structure of highly specific Aspergillus ribotoxin restrictocin. Structure. 4:1996;837-852.