Microbiological and biotechnological aspects of biodegradable plastics: Poly(hydroxyalkanoates)

Indian Journal of Biotechnology

Volumn 5, Issue 2, 2006, Pages 137-147

  Thakor, Nehal ^a   Trivedi, Ujjval ^a   Patel, K C ^a  

^a SARDAR PATEL UNIVERSITY   (India)

Author keywords

Bio polyesters; Biodegradable plastics; Biodegradation; PHAs; PHB

Indexed keywords

PLASTIC; POLY(3 HYDROXYBUTYRIC ACID); THIOESTER;

BIODEGRADATION; BIOSYNTHESIS; CHEMICAL STRUCTURE; FATTY ACID METABOLISM; FERMENTATION; METABOLIC ENGINEERING; POLYMERIZATION; REVIEW;

BACTERIA (MICROORGANISMS); PROKARYOTA;

EID: 33746092494     PISSN: 09725849     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (103)

1. Hocking P J & Marchessault R H, Biopolyesters, in Chemistry and technology of biodegradable polymers, edited by G J L Griffin (Chapman and Hall, London) 1994, 48-96.
2. Müller H M & Seebach D, Poly(hydroxyfettsäureester), eine fünfte Klasse von physiologisch bedeutsamen organischen biopolymeren?, Angew Chem, 105 (1993) 483-509.
3. Lemoigne M, Produits de deshydration et de polymerization de lácide β-oxybutyrique, Bull Soc Chim Bio, 8 (1926) 770-782.
4. Steinbüchel A & Füchtenbusch B, Bacterial and other biological systems for polyester production, Tibtech, 16 (1998) 419-427.
5. Anderson A J & Dawes E A, Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxy-alkanoates, Microbiol Rev, 54 (1990) 450-472.
6. Kessler B & Witholt B, Poly(3-hydroxyalkanoates), in Encyclopaedia of bioprocess technology: Fermentation, biocatalysis and bioseparation (John Wiley & Sons Inc., New York) 1999, 2024-2040.
7. Kim, Byung-KI, Yoon S C, Jae DD Nam & Lenz R W, Effect of C/N ratio on the production of poly(3-hydroxyalkanoates) by the methylotroph Paracoccus denetrificans, J Microbiol Biotechnol, 7 (1997) 391-396.
8. Lageveen R G, Huisman G W, Prevsting H, Ketelaar P, Eggink G et al, Formation of polyesters by Pseudomonas oleovorans: Effect of substrates on formation and composition of Poly-(R)-3-Hydroxyalkanoates and poly-(R)-3-hydroxyalkenoates, Appl Environ Microbiol, 54 (1988) 2924-2932.
9. Schlegel H G, Kaltwasser H & Gottschalk G, Ein submersverfahren zur Kultur wasserstoffoxidierender Bakterien: Wachstumsphysiologische Untersuchungen, Arch Mikrobiol, 38 (1961) 209-222.
10. 2 in Pseudomonas acidophila through introduction of the DNA fragment responsible for chemolithoautotrophic growth of Alcaligenes hydrogenophilus, Appl Environ Microbiol, 62 (1996) 1004-1007.
11. de Smet M J, Eggink G, Witholt B, Kingma J & Wynberg H, Characterization of intracellular inclusions formed by Pseudomonas oleovorans during growth on octane, J Bacteriol, 154 (1983) 870-878.
12. Steinbüchel A & Valentin H E, Diversity of bacterial polyhydroxyalkanoic acids, FEMS Microbiol Lett, 128 (1995) 219-228.
13. Abe C, Taima Y, Nakamura Y & Doi Y, New bacterial copolyesters of 3-hydroxyalkanoates and 3-hydroxy-ω-fluoroalkanoates produced by Pseudomonas oleovorans, Polym Commun, 31 (1990) 404-406.
14. Fritzsche K, Lenz R W & Fuller R C, An unusual bacterial polyester with a phenyl pendant group, Macromol Chem, 191 (1990) 1957-1965.
15. Marchessault R H & Yu G, Crystallization and material properties of polyhydroxyalkanoates, in Biopolymers, vol 3b, edited by Y Doi & A Steinbüchel (Wiley-VCH, Weinheim) 2002, 157-198.
16. Holmes P A, 3-Hydroxybutyrate polymer fibers (ICI), Eur Pat 104731, 1984.
17. Holmes P A, Collins S H & Wright L F, 3-Hydroxybutyrate polymers (ICI), US Pat 4447 654, 1984.
18. Jawed A & Gruys K J, Biodegradable Polymers (Biopol®), in Biopolymers, vol 4, edited by Y Doi & A Steinbüchel (Wiley-VCH, Weinheim) 2002, 53-68.
19. Shanks R A, Hodzic A & Wong S, Thermoplastic biopolyester natural fiber composites, J Appl Polym Sci, 91 (2003) 2114-2121.
20. van der Walle G A M, Buisman G J H, Weusthuis R A & Eggink G, Development of environmentally friendly coatings and paints using medium-chain-length poly(3-hydroxyalkanoates) as the polymer binder, Int J Biol Macromol, 25 (1999) 123-128.
21. Simon F & Martin D P, Applications of PHAs in medicine and pharmacy, in Biopolymers, vol 4, edited by Y Doi & A Steinbüchel (Wiley-VCH, Weinheim) 2002, 91-103.
22. Simon F, Martin D P, Horowitz D M & Peoples O P, PHA applications: Addressing price performance issue I. Tissue engineering, Int J Biol Macromol, 25 (1998) 111-121.
23. Pötter M, Madkour M H, Mayer F & Steinbüchel A, Regulation of phasin expression and polyhydroxyalkanoate (PHA) granule formation in Ralstonia eutropha H16, Microbiology, 148 (2002) 2413-2426.
24. Slepecky R A & Law J H, Synthesis and degradation of poly-β-hydroxybutyric acid in connection with sporulation of Bacillus megaterium, J Bacteriol, 82 (1961) 37-42.
25. Senior P J & Dawes E A, Poly-β-hydroxybutyrate biosynthesis and the regulation of glucose metabolism in Azotobacter beijerinckii, Biochem J, 125 (1971) 55-66.
26. Stam H, Van Verseveld H W, de Vries W & Stouthamer A H, Utilization of poly-β-hydroxybutyrate in free-living cultures of Rhizobium ORS571, FEMS Microbiol Lett, 35 (1986) 215-220.
27. Reusch R N & Sadoff H L, D(-)-Poly-β-hydroxybutyrate in membranes of genetically competent bacteria, J Bacteriol, 156 (1983) 778-788.
28. Reusch R N, Poly-β-hydroxybutyrate/calcium polyphosphate complexes in eukaryotic membranes, Proc Soc Exp Biol Med, 191 (1989) 377-381.
29. Moskowitz G J & Merrick J M, Metabolism of poly-β- hydroxybutyrate: Enzymatic synthesis of D(-)-β-hydroxybutyryl coenzyme A by an enoyl-hydratase from Rhodospirillum rubrum, Biochemistry, 8 (1969) 2748-2755.
30. Dawes E A, Microbial reserve compounds, edited by E A Dawes (Microbial Energetics, Blacki, London) 1986, 145-165.
31. Steinbüchel A & Schlegel H G, Physiology and molecular genetics of Poly(β-hydroxyalkanoic acid) synthesis in Alcaligenes eutrophus, Mol Microbiol, 5 (1991) 535-542.
32. Steinbüchel A & Lütke-Eversloh T, Metabolic engineering and pathway construction for biotechnological production of relevant polyhydroxyalkanoates in microorganisms, Biochem Eng J, 16 (2003) 81-96.
33. Steinbüchel A, Perspectives for biotechnological production and utilization of biopolymers: metabolic engineering of polyhydroxyalkanoate biosynthesis pathway as a successful example, Macromol Biosci, 1 (2001) 1-24.
34. Huisman G W, de Leeuw O, Eggink G & Witholt B, Synthesis of Poly-3-hydroxyalkanoates is a common feature of fluorescent Pseudomonads, Appl Environ Microbiol, 55 (1989) 1949-1954.
35. Ashby R D & Foglia T A, Poly(hydroxyalkanoates) biosynthesis from triglyceride substrates, Appl Microbiol Biotechnol, 49 (1998) 431-437.
36. Chung C W, Kim Y S, Kim Y B, Bae K S & Rhee Y H, Isolation of a Pseudomonas sp. strain exhibiting unusual behavior of poly(3-hydroxyalkanoates) biosynthesis and characterization of synthesized polyesters, J Microbiol Biotechnol, 9 (1999) 847-853.
37. Cromwick A M, Foglia T & Lenz R W, The microbial production of poly(hydroxyalkanoates) from tallow, Appl Microbiol Biotechnol, 46 (1996) 464-469.
38. Doi Y, Kitamura S & Abe H, Microbial synthesis and characterization of poly(3-hydroxybutyrate-co-hydroxyhexanoate), Macromolecules, 28 (1995) 4822-4828.
39. Kang H O, Chung C W, Kim H W, Kim Y B & Rhee Y H, Cometabolic biosynthesis of copolyesters consisting of 3-hydroxyvalerate and medium-chain-length 3-hydroxyalkanoates by Pseudomonas sp. DSY-82, Antonie van Leeuwenhoek, 80 (2001) 185-191.
40. Kato M, Bao H J, Kang C K, Fukui T & Doi Y, Production of a novel copolyester of 3-hydroxybutyric acid and medium chain length 3-hydroxyalkanoic acids by Pseudomonas sp. 61-3 from sugars, Appl Microbiol Biotechnol, 45 (1996) 363-370.
41. Steinbüchel A & Hein S, Biochemical and molecular basis of microbial synthesis of polyhydroxyalkanoates in micro-organisms, Adv Biochem Eng Biotechnol, 71 (2001) 81-123.
42. Haywood G W, Anderson A J & Dawes E A, The importance of PHB-synthase substrate specificity in polyhydroxyalkanoate synthesis by Alcaligenes eutrophus, FEMS Microbiol Lett, 57 (1989) 1-6.
43. Rehm B H A & Steinbüchel A, PHA synthases: The key enzymes of PHA synthesis, in Biopolymers, vol 3a, edited Y Doi & A Steinbüchel (Wiley-VCH, Weinheim) 2002, 173-215.
44. Antonio R V, Steinbüchel A & Rehm BHA, Analysis of in vivo substrate specificity of the PHA synthase from Ralstonia eutropha: Formation of novel copolyester in recombinant Escherichia coli, FEMS Microbiol Lett, 182 (2000) 111-117.
45. Dennis D, McCoy M, Stangl A, Valentin H E & Wu Z, 1998. Formation of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by PHA synthase from Ralstonia eutropha, J Bacteriol, 64 (1998) 177-186.
46. Langenbach S, Rehm B H A & Steinbüchel A, Functional expression of the PHA synthase gene phaC from Pseudomonas aeruginosa in Escherichia coli results in poly(3-hydroxyalkanoate) synthesis, FEMS Microbiol Lett, 150 (1997) 303-309.
47. 2, FEMS Microbiol Lett, 157 (1997) 155-162.
48. Qi Q, Steinbüchel A & Rehm B H A, Metabolic routing towards polyhydroxyalkanoic acid synthesis in recombinant Escherichia coli (fad R): Inhibition of fatty acid β-oxidation by acrylic acid, FEMS Microbiol Lett, 167 (1998) 89-94.
49. Thakor N S, Patel M A, Trivedi U B & Patel K C, Production of poly(β-hydroxybutyrate) by Comamonas testosteroni during growth on naphthalene, W J Microbiol Biotechnol, 19 (2003) 185-189.
50. Thakor N, Trivedi U B & Patel K C, Biosynthesis of medium-chain-length poly(3-hydroxyalkanoates) (mcl-PHAs) by Comamonas testosteroni during cultivation on vegetable oils, Bioresour Technol (DOI: 10.1016/jbiortech. 2005.01.030)
51. Lütke-Eversloh T, Bergander K, Luftmann H & Steinbüchel A, Biosynthesis of poly(3-hydroxybutyrate-co-3-mercaptobutyrate) as a sulfur analogue to poly(3-hydroxybutyrate) (PHB), Biomacromolecules, 2 (2001) 1061-1065.
52. Lütke-Eversloh T & Steinbüchel A, Microbial polythioesters, Macromol Biosci, 4 (2004) 165-174.
53. Lütke-Eversloh T, Fischer A, Remminghorst U, Kawada J, Marchessault R H et al, Biosynthesis of novel thermoplastic polythioesters by engineered Escherichia coli, Nat Mater, 1 (2002) 236-240.
54. Rehm B H A & Steinbüchel A, Biochemical and genetic analysis of PHA synthases and other proteins required for PHA synthesis, Int J Biol Macromol, 25 (1999) 3-19.
55. van der Walle G A M, de Koning G J H, Weusthuis R A & Eggink G, Properties, modifications and applications of biopolyesters, Adv Biochem Eng Biotechnol, 71 (2001) 264-291.
56. Cornibert J & Marchessault R H, Physical properties of poly-β-hydroxybutyrate IV. Conformational analysis and crystalline structure, J Mol Biol, 71 (1972) 735-756.
57. Okamura K & Marchessault R H, X-ray structure of poly-β- hydroxybutyrate, in Conformation of biopolymers, vol 2, edited by G M Ramchandran (Academic Press Inc., New York) 1967, 709-720.
58. Byrom D, Production of poly-β-hydroxybutyrate:poly-β- hydroxyvalerate copolymers, FEMS Microbiol Rev, 103 (1992) 247-250.
59. Lee S Y & Chang H N, Production of poly(hydroxyalkanoic acid), Adv Biochem Eng Biotechnol, 52 (1995) 27-58.
60. Lee S Y, Bacterial polyhydroxyalkanoates, Biotechnol Bioeng, 49 (1996) 1-14.
61. Steinbüchel A & Schmack G, Large scale production of poly(3-hydroxyvaleric acid) by fermentation of Chromobacterium violaceum, processing and characterization of the homopolyester, J Environ Polym Degrad, 3 (1995) 243-258.
62. Steinbüchel A, Valentin H E & Schonebaum A, Application of recombinant gene technology for production of polyhydroxyalkanoic acids: Biosynthesis of poly(4-hydroxybutyric acid) homopolyester, J Environ Polym Degrad, 2 (1994) 67-74.
63. T, J Ferment Bioeng, 71 (1991) 254-257.
64. Kim B S, Lee S C, Lee S Y, Chang H N, Chang Y K et al, Production of poly(3-hydroxybutyric acid) by fed-batch culture of Alcaligenes eutrophus with glucose concentration control, Biotechnol Bioeng, 43 (1994) 892-898.
65. Kim B S, Lee S C, Lee S Y, Chang H N, Chang Y K et al, Production of poly-(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) by fed-batch culture of Alcaligenes eutrophus with substrate feeding using on-line glucose analyzer, Enzyme Microb Technol, 16 (1994) 556-561.
66. Park C H & Damodaran V K, Biosynthesis of poly(3-hydroxybutyrate-co- 3-hydroxyvalerate) from ethanol and pentanol by Alcaligenes eutrophus, Biotechnol Prog, 10 (1994) 615-623.
67. Hangii U J, Pilot scale production of PHB with Alcaligenes latus, in Novel biodegradable microbial polymers, edited by E A Dawes (Kluwer Academic, Dordrecht, The Netherlands) 1990, 65-70.
68. Yamane T, Fukunage M & Lee Y W, Increased PHB productivity by high-cell-density fed-batch culture of Alcaligenes latus, a growth-associated PHB producer, Biotechnol Bioeng, 50 (1996) 197-202.
69. Page W J & Comish A, Growth of Azotobacter vinelandii UWD in fish peptone medium and simplified extraction of poly-β-hydroxybutyrate, Appl Environ Microbiol, 59 (1993) 4236-4244.
70. Kim S W, Kim P, Lee H S & Kim J H, High production of poly-β-hydroxybutyrate (PHB) from Methlobacterium organophilum under potassium limitation, Biotechnol Lett, 18 (1996) 25-30.
71. Suzuki T, Yamane T & Shimizu S, Mass production of poly-β-hydroxybutyric acid by fed-batch culture with controlled carbon/nitrogen feeding, Appl Microbiol Biotechnol, 24 (1986) 370-374.
72. Preusting H, Hazenberg W & Witholt B, Continuous production of poly(3-hydroxyalkanoates) by Pseudomonas oleovorans in high-cell-density, two-liquid-phase chemostat, Enzyme Microb Technol, 15 (1993) 311-316.
73. Preusting H, van Houten R, Hoefs A, van Langenberghe E K, Favre-Bulle O et al. High cell density cultivation of Pseudomonas oleovorans: Growth and production of poly(3-hydroxyalkanotes) in two-liquid phase batch and fed-batch system, Biotechnol Bioeng, 41 (1993) 550-556.
74. Fidler S & Dennis D, Polyhydroxyalkanoates production in recombinant Escherichia coli, FEMS Microbiol Rev, 103 (1992) 231-236.
75. Lee S Y & Chang H N, Production of poly(3-hydroxybutyric acid) by recombinant Escherichia coli strains: Genetics and fermentation studies, Can J Microbiol, 41 (1995) 207-215.
76. Lee S Y, Yim K S, Chang H N & Chang Y K, Construction of plasmids, estimation of plasmid stability, and use of stable plasmids for the production of poly(3-hydroxybutyric acid) in Escherichia coli, J Biotechnol, 32 (1994) 203-211.
77. Woo S A, Park S J & Lee S Y, Production of poly(3-hydroxybutyrate) from whey by cell recycle fed-batch culture of recombinant Escherichia coli, Biotech Lett, 23 (2001) 235-240.
78. Michele B K, Hazenberg W & Witholt B, High cell density fermentations of Pseudomonas oleovorans for the production of mcl-PHAs in two-liquid phase media, Enzyme Microb Technol, 24 (1999) 111-116.
79. Lee S Y, Plastic bacteria? Progress and prospects for polyhydroxyalkanoate production in bacteria, Tibtech, 14 (1996) 431-438.
80. Ryu H W, Hahn S K, Chang Y K & Chang H N, Production of poly(3-hydroxybutyrate) by high cell density fed-batch culture of Alcaligenes eutrophus with phosphate limitation, Biotechnol Bioeng, 55 (1997) 28-32.
81. Michele B K, Kessler B & Witholt B, Closed-loop control of bacterial high-cell-density fed-batch cultures: Production of mcl-PHAs by Pseudomonas putida KT2442 under single-substrate and co-feeding conditions, Biotechnol Bioeng, 65 (1998) 306-315.
82. Lee S Y, Choi J & Wong H H, Recent advances in polyhydroxyalkanoate production by bacterial fermentation: Mini review, Int J Biol Macromol, 25 (1999) 31-36.
83. Lee S Y, High cell-density culture of Escherichia coli, Tibtech, 14 (1996) 98-105.
84. Kessler B, Weusthuis R, Witholt B & Eggink G, Production of microbial polyesters: Fermentation and downstream process, Adv Biochem Eng Biotechnol, 71 (2001) 160-182.
85. Füchtenbusch B, Wullbrandt D & Steinbüchel A, Production of polyhydroxyalkanoic acids by Ralstonia eutropha and Psudomonas oleovorans from an oil remaining from biotechnological rhamnose production, Appl Microbiol Biotechnol, 53 (2000) 167-172.
86. Park S J, Park J P & Lee S Y, Production of poly(3-hydroxyalkanoate) from whey by fed-batch culture of recombinant Escherichia coli in pilot-scale fermenter, Biotechnol Lett, 24 (2002) 185-189.
87. Stefan K, Ren Q, Witholt B & Kessler B, Production of medium-chain-length poly(3-hydroxyalkanoates) from gluconate by recombinant Escherichia coli, Appl Environ Microbiol, 65 (1999) 540-548.
88. Matsusaki H, Abe H & Doi Y, Biosynthesis and properties of poly(3-hydroxybutyrate-co-3-hydroxyalkanoates) by recombinant strains of Pseudomonas sp. 61-3, Biomacromolecules, 1 (2000) 17-22.
89. Peoples O P & Sinskey A J, Poly-β-hydroxybutyrate (PHB) biosynthesis in Alcaligenes eutrophus H16: Identification and characterization of the PHB polymerase gene (phbC), J Biol Chem, 264 (1989) 15298-15303.
90. Schubert P, Steinbüchel A & Schlegel H G, Cloning of the Alcaligenes eutrophus genes for synthesis of poly-β-hydroxybutyric acid (PHB) and synthesis of PHB in Escherichia coli, J Bacteriol, 170 (1988) 5837-5847.
91. Slater S C, Voigt W H & Dennis D E, Cloning and expression in Escherichia coli of the Alcaligenes eutrophus H16 poly-β-hydroxybutyrate biosynthetic pathway, J Bacteriol, 170 (1988) 4431-4436.
92. Park J, Park H, Huh T & Lee Y, Production of poly-β- hydroxybutyrate by Alcaligenes eutrophus transformants harbouring cloned phbCAB genes, Biotechnol Lett, 17 (1995) 735-740.
93. Steinbüchel A & Schubert G, Expression of the Alcaligenes eutrophus poly(β-hydroxybutyric acid) synthetic pathway in Pseudomonas sp., Arch Microbiol, 153 (1989) 101-104.
94. Liebergesell M, Mayer F & Steinbüchel A, Analysis of polyhydroxyalkanoic acid-Biosynthesis genes of anoxygenic phototrophic bacteria reveals synthesis of a polyester exhibiting an unusual composition, Appl Microbiol Biotechnol, 40 (1993) 292-300.
95. Liu S J & Steinbüchel A, A novel genetically engineered pathway for synthesis of poly(hydroxyalkanoic acid) in Escherichia coli, Appl Environ Microbiol, 66 (2000) 739-743.
96. Thakor N, Lütke-Eversloh T & Steinbüchel A, Application of the BPEC pathway for biotechnological production of poly(3-mercaptopropionate) by recombinant Escherichia coli at large scale including a novel in situ isolation method, Appl Environ Microbiol, 71 (2005) 835-841.
97. Poirier Y, Green chemistry yields a better plastic, Nature Biotechnol, 17 (1999) 960-961.
98. Snell K D & Peoples O P, Polyhydroxyalkanoate polymers and their production in transgenic plants, Metab Eng, 4 (2002) 29-40.
99. Valentin H E, Broyles D L, Casagrande L A, Colburn S M, Creely W L et al, PHA production, from bacteria to plants, Int J Biol Macromol, 25 (1999) 303-306.
100. Jendrossek D & Hendrick R, Microbial degradation of polyhydroxyalkanoates, Annu Rev Microbiol, 56 (2002) 403-432.
101. Jendrossek D, Extracellular polyhydraxyalkanoate depolymerases: The key enzymes of PHA degradation, in Biopolymers, vol 3b, edited by Y Doi & A Steinbüchel (Wiley-VCH, Weinheim) 2002, 41-77.
102. Jendrossek D, Microbial degradation of polyesters, Adv Biochem Eng Biotechnol, 71 (2001) 294-325.
103. Brandl H, Bachofen R, Mayer J & Wintermantel E, Degradation and application of poly hydroxyalkanoates, Can J Microbiol, 41 (suppl 1)(1995) 143-153.