Derivatives of Z-Bisdehydrodoisynolic acid provide a new description of the binding-activity paradox and selective estrogen receptor modulator activity

Endocrinology

Volumn 147, Issue 8, 2006, Pages 3952-3960

  Adler, Molly ^a   Hou, Yuqing ^b   Sandrock, Paul ^b   Meyers, Cal Y ^b   Winters, Todd A ^a,b   Banz, William J ^a,b   Adler, Stuart ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; AMIDE; CARBOXYLIC ACID DERIVATIVE; ESTER; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FENOCYLIN; SELECTIVE ESTROGEN RECEPTOR MODULATOR; UNCLASSIFIED DRUG; Z BISDEHYDRODOISYNOLIC ACID [8 ETHYL 7 HYDROXYMETHYL 7 METHYL 5,6,7,8 TETRAHYDRO PHENANTHRENE 2 OL]; Z BISDEHYDRODOISYNOLIC ACID AMIDE; Z BISDEHYDRODOISYNOLIC ACID DERIVATIVE; Z BISDEHYDRODOISYNOLIC ACID METHYL ESTER;

ACID BASE BALANCE; ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG INHIBITION; DRUG POTENCY; DRUG PROTEIN BINDING; ENANTIOMER; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; PH MEASUREMENT; POLARIZATION; PRIORITY JOURNAL; REPORTER GENE;

ALCOHOLS; AMIDES; BINDING, COMPETITIVE; DRUG DESIGN; ESTERS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GENE EXPRESSION; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; PHENANTHRENES; PROTEIN BINDING;

EID: 33746064839     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0316     Document Type: Article

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