Estradiol-16α-carboxylic acid esters as locally active estrogens

Journal of Medicinal Chemistry

Volumn 44, Issue 11, 2001, Pages 1802-1814

  Labaree, D C ^a   Reynolds, T Y ^a   Hochberg, R B ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ESTRADIOL; ESTRADIOL 16ALPHA CARBOXYLIC ACID ESTER; ESTRADIOL DERIVATIVE; ESTROGEN; ESTROGEN RECEPTOR; FORMIC ACID; PROPIONIC ACID; UNCLASSIFIED DRUG; ALKALINE PHOSPHATASE; DRUG DERIVATIVE; ESTER; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; OXIDOREDUCTASE;

ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; ESTROGEN ACTIVITY; HUMAN; HUMAN CELL; HYDROLYSIS; NONHUMAN; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; ANIMAL; BINDING COMPETITION; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; DRUG EFFECT; ENZYME INDUCTION; ENZYMOLOGY; FEMALE; HISTOLOGY; IN VITRO STUDY; LIVER MICROSOME; METABOLISM; MOUSE; ORGAN SIZE; OVARIECTOMY; SPRAGUE DAWLEY RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS; UTERUS; VAGINA;

ALKALINE PHOSPHATASE; ANIMALS; BINDING, COMPETITIVE; ENZYME INDUCTION; ESTERS; ESTRADIOL; ESTRADIOL CONGENERS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HUMANS; MICE; MICROSOMES, LIVER; ORGAN SIZE; OVARIECTOMY; OXIDOREDUCTASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; UTERUS; VAGINA;

EID: 0035942484     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000523h     Document Type: Article

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