Anti-C1q antibodies in hepatitis C virus infection

Clinical and Experimental Immunology

Volumn 145, Issue 2, 2006, Pages 308-312

  Saadoun, D ^a   Sadallah, S ^b   Trendelenburg, M ^b   Limal, N ^a   Sene, D ^a   Piette, J C ^a   Schifferli, J A ^b   Cacoub, P ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Anti C1q antibodies; Autoantibodies; Hepatitis C; Mixed cryoglobulinaemia; Vasculitis

Indexed keywords

COMPLEMENT COMPONENT C1Q ANTIBODY; COMPLEMENT COMPONENT C4; CRYOGLOBULIN; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIBODY DETECTION; ARTICLE; BLOOD DONOR; CLINICAL FEATURE; CONTROLLED STUDY; CRYOGLOBULINEMIA; DISEASE ASSOCIATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; RISK ASSESSMENT; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC VASCULITIS;

EID: 33745955391     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2006.03153.x     Document Type: Article

References (22)

1. Gorevic PD, Kassab HJ, Levo Y et al. Mixed cryoglobulinemia: clinical aspects and long-term follow-up of 40 patients. Am J Med 1980; 69:287-308.
2. Cacoub P, Renou C, Rosenthal E et al. Extrahepatic manifestations associated with hepatitis C virus infection. A prospective multicenter study of 321 patients. The GERMIVIC Groupe d'Etude et de Recherche en Medecine Interne et Maladies Infectieuses sur le Virus de l'Hepatite C. Medicine (Balt) 2000; 79:47-56.
3. Walport MJ. Complement. Second of two parts. N Engl J Med 2001; 344:1140-4.
4. Seelen MA, Trouw LA, Daha MR. Diagnostic and prognostic significance of anti-C1q antibodies in systemic lupus erythematosus. Curr Opin Nephrol Hypertens 2003; 12:619-24.
5. Tan EM, Cohen AS, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25:1271-7.
6. Siegert CE, Daha MR, van der Voort EA, Breedveld FC. IgG and IgA antibodies to the collagen-like region of C1q in rheumatoid vasculitis. Arthritis Rheum 1990; 33:1646-54.
7. Trendelenburg M, Marfurt J, Gerber I, Tyndall A, Schifferli JA. Lack of occurrence of severe lupus nephritis among anti-C1q autoantibody-negative patients. Arthritis Rheum 1999; 42:187-8.
8. Brouet JC, Clauvel JP, Danon F, Klein M, Seligmann M. Biologic and clinical significance of cryoglobulins. A report of 86 cases. Am J Med 1974; 57:775-88.
9. Bedossa P, Poynard T for the French METAVIR Cooperative Study Group. Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. Hepatology 1994; 20:15-20.
10. Siegert C, Daha M, Westedt ML, van der Voort E, Breedveld F. IgG autoantibodies against C1q are correlated with nephritis, hypocomplementemia, and dsDNA antibodies in systemic lupus erythematosus. J Rheumatol 1991; 18:230-4.
11. Wener MH, Uwatoko S, Mannik M. Antibodies to the collagen-like region of C1q in sera of patients with autoimmune rheumatic diseases. Arthritis Rheum 1989; 32:544-51.
12. Kittlesen DJ, Chianese-Bullock KA, Yao ZQ, Braciale TJ, Hahn YS. Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation. J Clin Invest 2000; 106:1239-49.
13. Sansonno D, Lauletta G, Nisi L et al. Non-enveloped HCV core protein as constitutive antigen of cold-precipitable immune complexes in type II mixed cryoglobulinaemia. Clin Exp Immunol 2003; 133:275-82.
14. Feng X, Tonnesen MG, Peerschke EI, Ghebrehiwet B. Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading. J Immunol 2002; 168:2441-8.
15. Kohro-Kawata J, Wener MH, Mannik M. The effect of high salt concentration on detection of serum immune complexes and autoantibodies to C1q in patients with systemic lupus erythematosus. J Rheumatol 2002; 29:84-9.
16. Sansonno D, Dammacco F. Hepatitis C virus, cryoglobulinaemia, and vasculitis: immune complex relations. Lancet Infect Dis 2005; 5:227-36.
17. Golan MD, Burger R, Loos M. Conformational changes in C1q after binding to immune complexes: detection of neoantigens with monoclonal antibodies. J Immunol 1982; 129:445-7.
18. Haydey RP, Patarroyo de Rojas M, Gigli I. A newly described control mechanism of complement activation in patients with mixed cryoglobulinemia (cryoglobulins and complement). J Invest Dermatol 1980; 74:328-32.
19. Botto M, Walport MJ. C1q, autoimmunity and apoptosis. Immunobiology 2002; 205:395-406.
20. Roccatello D, Morsica G, Picciotto G et al. Impaired hepatosplenic elimination of circulating cryoglobulins in patients with essential mixed cryoglobulinaemia and hepatitis C virus (HCV) infection. Clin Exp Immunol 1997; 110:9-14.
21. Roccatello D, Isidoro C, Mazzucco G et al. Role of monocytes in cryoglobulinemia-associated nephritis. Kidney Int 1993; 43:1150-5.
22. Squadrito G, Previti M, Lenzi M et al. High prevalence of non-organ-specific autoantibodies in hepatitis C virus-infected cirrhotic patients from southern Italy. Dig Dis Sci 2003; 48:349-53.