Bucillamine induces glutathione biosynthesis via activation of the transcription factor Nrf2

Biochemical Pharmacology

Volumn 72, Issue 4, 2006, Pages 455-462

  Wielandt, Ana M ^a   Vollrath, Valeska ^a   Farias, Marcelo ^a   Chianale, Jose ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Bucillamine; Glutamate cysteine ligase (GCL); Glutathione (GSH); Multidrug resistance associated protein 2(Mrp2 MRP2); Nuclear factor erythroid 2 p45 related factor (Nrf2)

Indexed keywords

4,5,6,7 TETRAHYDRO 7,7 DIMETHYL 6 OXO 3H 1,2,5 DITHIAZEPINE 4 CARBOXYLIC ACID; BUCILLAMINE; DRUG METABOLITE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN 2; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CANCER PREVENTION; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INDUCTION; EXCRETION; GENE EXPRESSION; GLUTATHIONE METABOLISM; HEPATOMA CELL; HUMAN; HUMAN CELL; HYPOTHESIS; LIVER CELL; LIVER CELL CARCINOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CATALYTIC DOMAIN; CELL LINE, TUMOR; CELL NUCLEUS; CYSTEINE; GENE EXPRESSION; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR STRUCTURE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NF-E2 TRANSCRIPTION FACTOR, P45 SUBUNIT; RNA, MESSENGER;

EID: 33745938529     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.05.011     Document Type: Article

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