A model of autosomal recessive Alport syndrome in English cocker spaniel dogs

Kidney International

Volumn 54, Issue 3, 1998, Pages 706-719

  Lees, G E ^a   Helman, R G ^a   Kashtan, C E ^a   Michael, A F ^a   Homco, L D ^a   Millichamp, N J ^a   Ninomiya, Y ^a   Sado, Y ^a   Naito, I ^a   Kim, Y ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Basement membrane; Chronic renal failure; Genetic disorder; Hereditary nephritis; Multilamination; Progressive glomerular disease; Type IV collagen

Indexed keywords

COLLAGEN TYPE 4;

ALPHA CHAIN; ALPORT SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CELL ULTRASTRUCTURE; CHRONIC KIDNEY FAILURE; CLINICAL FEATURE; DISEASE SEVERITY; DOG; GLOMERULUS BASEMENT MEMBRANE; IMMUNOHISTOCHEMISTRY; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA;

EID: 0031713744     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00062.x     Document Type: Article

References (50)

1. C.E. Kashtan A.F. Michael Perspectives in clinical nephrology: Alport syndrome Kidney Int 50 1996 1445 1463
2. C.E. Kashtan R.K. Sibley A.F. Michael R.L. Vernier Hereditary nephritis: Alport syndrome and thin glomerular basement membrane disease (chapt 39) C.C. Tisher B.M. Brenner Renal Pathology 2nd 1994 J.B. Lippincott Philadelphia 1239 1267
3. M. Gregory C.L. Atkin Alport syndrome (chapt 19) R.W. Schrier C.W. Gottschalk Diseases of the Kidney 1993 Little, Brown Boston 571 591
4. K. Tryggvason N. Heiskari Alport syndrome (chapt 53) D. Schlondorff J.V. Bonventre Molecular Nephrology: Kidney Function in Health and Disease 1995 Marcel Dekker, Inc. New York 795 808
5. T. Mochizuki H.H. Lemmink M. Mariyama C. Antignac M.C. Gubler Y. Pirson C. Verellen-Dumoulin B. Chan C.H. Schroder H.J. Smeets S.T. Reeders Identification of mutations in the alpha-3(IV) and alpha-4(IV) collagen genes in autosomal recessive Alport syndrome Nature Genetics 8 1994 77 82
6. J. Ding J. Stitzel P. Berry E. Hawkins C.E. Kashtan Autosomal recessive Alport syndrome: Mutation in the COL4A3 gene in a woman with Alport syndrome and posttransplant antiglomerular basement membrane nephritis J Am Soc Nephrol 5 1996 1714 1717
7. H.H. Lemmink T. Mochizuki L.P.W.J. van den Heuvel C.H. Schroder A. Barrientos L.A.H. Monnens B.A. van Oost H.G. Brunner S.T. Reeders H.J. Smeets Mutations in the type IV collagen α 3 (COL4A3) gene in autosomal recessive Alport syndrome Hum Mol Genet 3 1994 1269 1273
8. B. Knebelmann L. Forestier L. Drouot S. Quinowes C. Chuet F. Benessy J. Saus C. Antignac Splice-mediated insertion of an Alu sequence in the COL4A3 mRNA causing autosomal recessive Alport syndrome Hum Mol Genet 4 1995 675 679
9. J. Feingold E. Bois A. Chompret M. Broyer M.C. Gubler J.P. Grünfeld Genetic heterogeneity of Alport syndrome Kidney Int 27 1985 672 677
10. J.A. Jefferson H.H. Lemmink D.D. Hunter C.M. Hill H.J. Smeets C.C. Doherty A.P. Maxwell Autosomal dominant Alport syndrome linked to the type IV collagen alpha 3 and alpha 4 genes (COL4A3 and COL4A4) Nephrol Dial Transplant 12 1997 1595 1599
11. B. Jansen P.S. Thorner A. Singh J.M. Patterson J.H. Lumsden V.E. Valli R. Baumal P.K. Basrur Hereditary nephritis in Samoyed dogs Am J Pathol 116 1984 175 178
12. B. Jansen L. Tryphonas J. Wong P. Thorner M.G. Maxie V.E. Valli R. Baumal P.K. Basrur Mode of inheritance of Samoyed hereditary glomerulopathy: An animal model for hereditary nephritis in humans J Lab Clin Med 107 1986 551 555
13. B. Jansen P. Thorner R. Baumal V. Valli M.G. Maxie A. Singh Samoyed hereditary glomerulopathy (SHG): Evolution of splitting of glomerular capillary basement membranes Am J Pathol 125 1986 536 545
14. P. Thorner B. Jansen R. Baumal V.E. Valli A. Goldberger Samoyed hereditary glomerulopathy: Immunohistochemical staining of basement membranes of kidney for laminin, collagen type IV, fibronectin, and Goodpasture antigen, and correlation with electron microscopy of glomerular capillary basement membranes Lab Invest 56 1987 435 443
15. B. Jansen V.E.O. Valli P. Thorner R. Baumal J.H. Lumsden Samoyed hereditary glomerulopathy: Serial clinical and laboratory (urine, serum biochemistry, and hematology) studies Can J Vet Res 51 1987 387 393
16. R. Baumal P. Thorner V.E.O. Valli R. McInnes P. Marrano R. Jacobs A. Binnington A.G. Bloedow Renal disease in carrier female dogs with X-linked hereditary nephritis Am J Pathol 139 1991 751 764
17. K. Zheng P.S. Thorner P. Marrano R. Baumal R.R. McInnes Canine X chromosome-linked hereditary nephritis: A genetic model for human X-linked hereditary nephritis resulting from a single base mutation in the gene encoding the α 5 chain of collagen type IV Proc Natl Acad Sci USA 91 1994 3989 3993
18. J.C. Hood J. Savige A. Hendtlass M.M. Kleppel C.R. Huxtable W.F. Robinson Bull terrier hereditary nephritis: A model for autosomal dominant Alport syndrome Kidney Int 47 1995 758 765
19. G.E. Lees P.D. Wilson G.H. Helman L.D. Homco M.S. Frey Glomerular ultrastructural findings similar to hereditary nephritis in 4 English cocker spaniels J Vet Int Med 11 1997 80 85
20. G.E. Lees G.H. Helman L.D. Homco N.J. Millichamp J.F. Hunter M. Frey Early diagnosis of familial nephropathy in English cocker spaniels J Am Anim Hosp Assoc 34 1998 189 195
21. L. Krook The pathology of renal cortical hypoplasia in the dog Nord Vet-Med 9 1957 161 176
22. F. Persson S. Persson A. Asheim Renal cortical hypoplasia in dogs: A clinical study on uraemia and secondary hyperparathyroidism Acta Vet Scand 2 1961 68 84
23. U. Freudiger Die kongenitale nierenrindenhypoplasie beim bunten cocker-spaniel Schweizer Arch Tierheilk 107 1965 547 566
24. A.P. Steward D.F. Macdougall Familial nephropathy in the cocker spaniel J Small Anim Pract 25 1984 15 24
25. W.F. Robinson C.R. Huxtable J.P. Gooding Familial nephropathy in cocker spaniels Aust Vet J 62 1985 109 112
26. J.P. Koeman J.W. Ezilius W.J. Biewenga W.E. Brom E. Gruys Zur familiaren nephropathie der cockerspaniel Dtsch Tierarzti Wschr 96 1989 174 179
27. D.F. Macdougall A.S. Nash B.M. Cattanach Control scheme for familial nephropathy in cocker spaniels. (letter) Vet Rec 121 1987 134
28. M.M. Kleppel C.E. Kashtan P.A. Santi J. Wieslander A.F. Michael Distribution of familial nephritis antigen in normal tissue and renal basement membranes of patients with homozygous and heterozygous Alport familial nephritis: Relationship of familial nephritis and Goodpasture antigens to novel collagen chains and type IV collagen Lab Invest 61 1989 278 289
29. K. Nakanishi N. Yoshikawa K. Iijima K. Kitagawa H. Nakamura H. Ito K. Yoshioka M. Kagawa Y. Sado Immunohistochemical study of α 1-5 chains of type IV collagen in hereditary nephritis Kidney Int 46 1994 1413 1421
30. C.E. Kashtan Y. Kim Distribution of the α 1 and α 2 chains of collagen IV and of collagens V and VI in Alport syndrome Kidney Int 42 1992 115 126
31. K. Yoshioka S. Hino T. Takemura S. Maki J. Wieslander Y. Takekoshi H. Makino M. Kagawa Y. Sado C.E. Kashtan Type IV collagen α 5 chain: Normal distribution and abnormalities in X-linked Alport syndrome revealed by monoclonal antibody Am J Pathol 144 1994 986 996
32. M.C. Gubler B. Knebelmann A. Beziau M. Broyer Y. Pirson F. Haddum M.M. Kleppel C. Antignac Autosomal recessive Alport syndrome: Immunohistochemical study of type IV collagen chain distribution Kidney Int 47 1996 1142 1147
33. J.H. Miner J.R. Sanes Molecular and functional defects in kidneys of mice lacking collagen α 3(IV): Implications for Alport syndrome J Cell Biol 135 1996 1403 1413
34. D. Cosgrove D.T. Meehan J.A. Grunkemeyer J.M. Kornak R. Sayers W.J. Hunter G.C. Samuelson Collagen COL4A3 knockout: A mouse model for autosomal Alport syndrome Genes Dev 10 1996 2981 2992
35. D.B. Coulter J.C. Keith Blood pressures obtained by indirect measurement in conscious dogs J Am Vet Med Assoc 184 1984 1375 1378
36. K.M. Meurs M.W. Miller M.R. Slater Comparison of the indirect oscillometric and direct arterial methods for blood pressure measurement in anesthetized dogs J Am Anim Hosp Assoc 32 1996 471 475
37. R.D. Bodenhamer J.F. Hunter P.J. Luttgen Brain stem auditory-evoked responses in the dog Am J Vet Res 46 1985 1787 1792
38. H.G. Foellmer J.A. Madri H. Furthmayr Monoclonal antibodies to type IV collagen: Probes for the study of structure and function of basement membranes Lab Invest 48 1983 639 649
39. R.J. Butkowski J. Wieslander M.M. Kleppel A.F. Michael A.J. Fish Basement membrane collagen in the kidney: Regional localization of novel chains related to collagen IV Kidney Int 35 1989 1195 1202
40. M.M. Kleppel A.F. Michael Expression of novel basement membrane components in the developing human kidney and eye Am J Anat 187 1990 165 174
41. J.H. Miner J.R. Sanes Collagen IV α 3, α 4, and α 5 chains in rodent basal laminae: Sequence, distribution, association with laminins, and developmental switches J Cell Biol 127 1994 879 891
42. J. Ding C.E. Kashtan W. Fan M.M. Kleppel M.J. Sun R. Kalluri E.G. Neilson A.F. Michael A monoclonal antibody marker for Alport syndrome identifies the Alport antigen as the α 5 chain of type IV collagen Kidney Int 46 1994 1504 1506
43. I. Naito S. Kawai S. Nomura Y. Sado G. Osawa Japanese Alport Network Relationship between COL4A5 gene mutation and distribution of type IV collagen in male X-linked Alport syndrome Kidney Int 50 1996 304 311
44. Y. Sado M. Kagawa Y. Kishiro K. Sugihara I. Naito J. Seyer M. Sugimoto T. Oohashi Y. Ninomiya Establishment by the rat lymph node method of epitope-defined monoclonal antibodies recognizing the six different α chains of human type IV collagen Histochem Cell Biol 104 1995 267 275
45. J.C. Hood W.F. Robinson W.T. Clark R.J. Sutherland I. James M.A.B. Thomas C.R. Huxtable Proteinuria as an indicator of early renal disease in Bull terriers with hereditary nephritis J Small Anim Pract 32 1991 241 248
46. H.J. Rumpelt Hereditary nephropathy (Alport syndrome): Correlation of clinical data with glomerular basement membrane alterations Clin Nephrol 13 1980 203 207
47. M.M. Kleppel P.A. Santi J.D. Cameron J. Wieslander A.F. Michael Human tissue distribution of novel basement membrane collagen Am J Pathol 134 1989 813 825
48. B. Peissel L. Geng R. Kalluri C.E. Kashtan H.G. Rennke G. Gallo K. Yoshioka M.J. Sun B.G. Hudson E.G. Neilson J. Zhou Comparative distribution of the α 1(IV), α 5(IV), and α 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients J Clin Invest 96 1995 1948 1957
49. Y. Ninomiya M. Kagawa K. Iyama I. Naito Y. Kishiro J. Seyer M. Sugimoto T. Oohashi Y. Sado Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies J Cell Biol 130 1995 1219 1229
50. P.S. Thorner K. Zheng R. Kalluri R. Jacobs B.G. Hudson Coordinate gene expression of the α 3, α 4, and α 5 chains of collagen type IV; Evidence from a canine model of X-linked nephritis with a COL4A5 gene mutation J Biol Chem 271 1996 13821 13828