A transcriptional enhancer required for the differential expression of the human estrogen receptor in breast cancers

Molecular and Cellular Biology

Volumn 17, Issue 3, 1997, Pages 1274-1280

  Tang, Zuoqin ^a   Treilleux, Isabelle ^a,b   Brown, Myles ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b CENTRE LÉON BÉRARD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; BREAST CANCER; DNA PROTEIN COMPLEX; ENHANCER REGION; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; METHYLATION; PLASMID; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION;

EID: 0031024808     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.3.1274     Document Type: Article

References (29)

1. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1995. Current protocols in molecular biology. John Wiley & Sons, Inc., Boston, Mass.
2. Barrett, L. P., M. T. Travers, R. A. McClelland, Y. Luqmani, and R. C. Coombes. 1987. Characterization of estrogen receptor messenger RNA in human breast cancer. Cancer Res. 47:6653-6659.
3. Bohmann, D., T. J. Bos, A. Admon, T. Nishimura, P. K. Vogt, and R. Tjian. 1987. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science 238:1386-1392. (Review.)
4. deConinck, E. C., L. A. McPherson, and R. J. Weigel. 1995. Transcriptional regulation of estrogen receptor in breast carcinomas. Mol. Cell. Biol. 15: 2191-2196.
5. Ferguson, A. T., R. G. Lapidus, S. B. Baylin, and N. E. Davidson. 1995. Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression. Cancer Res. 55:2279-2283.
6. Gaub, M. P., M. Bellard, I. Scheuer, P. Chambon, and C. P. Sassone. 1990. Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex. Cell 63:1267-1276.
7. Grandien, K., M. Backdahl, O. Ljunggren, J. A. Gustafsson, and A. Berkenstam. 1995. Estrogen target tissue determines alternative promoter utilization of the human estrogen receptor gene in osteoblasts and tumor cell lines. Endocrinology 136:2223-2229.
8. Green, S., P. Walter, V. Kumar, A. Krust, J. M. Bornert, P. Argos, and P. Chambon. 1986. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature 320:134-139.
9. Hanstein, B., R. Eckner, J. DiRenzo, S. Halachmi, H. Liu, B. Searcy, and M. Brown. 1996. p300 is a component of an estrogen receptor coactivator complex. Proc. Natl. Acad. Sci. USA 93:11540-11545.
10. Harris, J. R., S. Hellman, I. C. Henderson, and D. W. Kinne (ed.). 1991. Breast disease. J. B. Lippincott Co., Philadelphia, Pa.
11. Henderson, B. E., R. Ross, and L. Bernstein. 1988. Estrogens as a cause of human cancer: the Richard and Hinda Rosenthal Foundation award lecture. Cancer Res. 48:246-253. (Review.)
12. Henry, J. A., S. Nicholson, J. R. Farndon, B. R. Westley, and F. E. May. 1988. Measurement of oestrogen receptor mRNA levels in human breast tumours. Br. J. Cancer 58:600-605.
13. Herrera, R., S. Agarwal, K. Walton, B. Satterberg, R. J. Distel, R. Goodman, B. M. Spiegelman, and T. M. Roberts. 1990. A direct role for c-fos in AP-1-dependent gene transcription. Cell Growth Differ. 1:483-490.
14. Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S. Lin, R. A. Heyman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403-414.
15. Katzenellenbogen, B. S. 1991. Antiestrogen resistance: mechanisms by which breast cancer cells undermine the effectiveness of endocrine therapy. J. Natl. Cancer Inst. 83:1434-1435. (Editorial.)
16. Keaveney, M., J. Klug, M. T. Dawson, P. V. Nestor, J. G. Neilan, R. C. Forde, and F. Gannon. 1991. Evidence for a previously unidentified upstream exon in the human oestrogen receptor gene. J. Mol. Endocrinol. 6:111-115.
17. Koh, E. H., J. Ro, D. M. Wildrick, G. N. Hortobagyi, and M. Blick. 1989. Analysis of the estrogen receptor gene structure in human breast cancer. Anticancer Res. 9:1841-1845.
18. Luckow, B., and G. Schutz. 1987. CAT constructions with multiple unique restriction sites for the functional analysis of cukaryotic promoters and regulatory elements. Nucleic Acids Res. 15:5490.
19. Ottaviano, Y. L., J. P. Issa, F. F. Parl, H. S. Smith, S. B. Baylin, and N. E. Davidson. 1994. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res. 54:2552-2555.
20. Parl, F. F., D. R. Cavener, and W. D. Dupont. 1989. Genomic DNA analysis of the estrogen receptor gene in breast cancer. Breast Cancer Res. Treatment 14:57-64.
21. Philips, A., D. Chalbos, and H. Rochefort. 1993. Estradiol increases and anti-estrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells without affecting c-fos and c-jun synthesis. J. Biol. Chem. 268:14103-14108. (Erratum, 268:26032.)
22. Piva, R., N. Bianchi, G. L. Aguiari, R. Gambari, and L. del Senno. 1993. Sequencing of an RNA transcript of the human estrogen receptor gene: evidence for a new transcriptional event. J. Steroid Biochem. Mol. Biol. 46:531-538.
23. Piva, R., L. V. Kumar, S. Hanau, I. Maestri, A. P. Rimondi, S. F. Pansini, G. Mollica, P. Chambon, and L. del Senno. 1989. The methylation pattern in the 5′ end of the human estrogen receptor gene is tissue specific and related to the degree of gene expression. Biochem. Int. 19:267-275.
24. Rio, M. C., J. P. Bellocq, B. Gairard, U. B. Rasmussen, A. Krust, C. Koehl, H. Calderoli, V. Schiff, R. Renaud, and P. Chambon. 1987. Specific expression of the pS2 gene in subclasses of breast cancers in comparison with expression of the estrogen and progesterone receptors and the oncogene ERBB2. Proc. Natl. Acad. Sci. USA 84:9243-9247.
25. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
26. Umayahara, Y., R. Kawamori, H. Watada, E. Imano, N. Iwama, T. Morishima, Y. Yamasaki, Y. Kajimoto, and T. Kamada. 1994. Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer. J. Biol. Chem. 269:16433-16442.
27. Webb, P., G. N. Lopez, R. M. Uht, and P. J. Kushner. 1995. Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens. Mol. Endocrinol. 9:443-456.
28. Weigel, R. J., D. L. Crooks, J. D. Iglehart, and E. C. deConinck. 1995. Quantitative analysis of the transcriptional start sites of estrogen receptor in breast carcinoma. Cell Growth Differ. 6:707-711.
29. Weigel, R. J., and E. C. deConinck. 1993. Transcriptional control of estrogen receptor in estrogen receptor-negative breast carcinoma. Cancer Res. 53: 3472-3474.