Hydroxyethyl starch exhibits antiinflammatory effects in the intestines of endotoxemic rats

Anesthesia and Analgesia

Volumn 103, Issue 1, 2006, Pages 149-155

  Lv, Ran ^b   Zhou, Zhi Qiang ^b   Wu, Hai Wei ^b   Jin, Yi ^b   Zhou, Wei ^b   Xu, Jian Guo ^a  

^a JINLING HOSPITAL   (China)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; HETASTARCH; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOPEROXIDASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; ENZYME ACTIVATION; GRAM NEGATIVE INFECTION; INTESTINE EPITHELIUM; INTESTINE MUCOSA; MALE; MEDIATOR RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; SEPSIS;

EID: 33745815700     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000220906.74517.99     Document Type: Article

References (23)

1. Zhang FX, Kirschning CJ, Mancinelli R, et al. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem 1999;274:7611-4.
2. Pritts TA, Moon R, Fischer JE, et al. Nuclear factor-kappaB is activated in intestinal mucosa during endotoxemia. Arch Surg 1998;133:1311-5.
3. Meyer TA, Wang J, Tiao GM, et al. Sepsis and endotoxemia stimulate intestinal interleukin-6 production. Surgery 1995;118:336-42.
4. Magnotti LJ, Upperman JS, Xu DZ, et al. Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock. Ann Surg 1998;228:518-27.
5. Langkamp-Henken B, Donovan TB, Pate LM, et al. Increased intestinal permeability following blunt and penetrating trauma. Crit Care Med 1995;23:660-4.
6. Groeneveld AB. Albumin and artificial colloids in fluid management: where does the clinical evidence of their utility stand? Crit Care 2000;4 Suppl 2:S16-20.
7. Nicholson JP, Wolmarans MR, Park GR. The role of albumin in critical illness. Br J Anaesth 2000;85:599-610.
8. Hofbauer R, Moser D, Hornykewycz S, et al. Hydroxyethyl starch reduces the chemotaxis of white cells through endothelial cell monolayers. Transfusion 1999;39:289-94.
9. Collis RE, Collins PW, Gutteridge CN, et al. The effect of hydroxyethyl starch and other plasma volume substitutes on endothelial cell activation: an in vitro study. Intensive Care Med 1994;20:37-41.
10. Lang K, Suttner S, Boldt J, et al. Volume replacement with HES 130/0.4 may reduce the inflammatory response in patients undergoing major abdominal surgery. Can J Anaesth 2003;50:1009-16.
11. Tian J, Lin X, Zhou W, Xu JG. Hydroxyethyl starch inhibits NF-kappaB activation and prevents the expression of inflammatory mediators in endotoxic rats. Ann Clin Lab Sci 2003;33:451-8.
12. Tian J, Lin X, Guan R, Xu JG. The effects of hydroxyethyl starch on lung capillary permeability in endotoxic rats and possible mechanisms. Anesth Analg 2004;98:768-74.
13. Lentsch AB, Ward PA. Regulation of inflammatory vascular damage. J Pathol 2000;190:343-8.
14. Kang JS, Yoon YD, Lee KH, et al. Costunolide inhibits interleukin-1beta expression by down-regulation of AP-1 and MAPK activity in LPS-stimulated RAW 264.7 cells. Biochem Biophys Res Commun 2004;313:171-7.
15. Sun J, Wang XD, Liu H, Xu JG. Ketamine suppresses endotoxin-induced NF-kappaB activation and cytokines production in the intestine. Acta Anaesthesiol Scand 2004;48:317-21.
16. Kaplan SS, Park TS, Gonzales ER, Gidday JM. Hydroxyethyl starch reduces leukocyte adherence and vascular injury in the newborn pig cerebral circulation after asphyxia. Stroke 2000;31:2218-23.
17. Ishii H, Ishibashi M, Takayama M, et al. The role of cytokine-induced neutrophil chemoattractant-1 in neutrophil-mediated remote lung injury after intestinal ischaemia/reperfusion in rats. Respirology 2000;5:325-31.
18. Schmand JF, Ayala A, Morrison MH, Chaudry IH. Effects of hydroxyethyl starch after trauma-hemorrhagic shock: restoration of macrophage integrity and prevention of increased circulating interleukin-6 levels. Crit Care Med 1995;23:806-14.
19. Lockyer JM, Colladay JS, Alperin-Lea WL, et al. Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells. Circ Res 1998;82:314-20.
20. Woronicz JD, Gao X, Cao Z, et al. IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. Science 1997;278:866-9.
21. Pritts TA, Wang Q, Sun X, et al. Induction of the stress response in vivo decreases nuclear factor-kappa B activity in jejunal mucosa of endotoxemic mice. Arch Surg 2000;135:860-6.
22. Barnes PJ, Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-71.
23. Lo YY, Cruz TF. Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes. J Biol Chem 1995;270:11727-30.