Proapoptotic activity of NAG-1 is cell type specific and not related to COX-2 expression

Apoptosis

Volumn 11, Issue 7, 2006, Pages 1131-1138

  Jang, Tae Jung ^a   Kim, Nam Ii ^a   Lee, Chang Hun ^b  

^a Dongguk University College of Medicine   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

Author keywords

Apoptosis; COX 2; Gastric cancer cells; Hepatocelluar carcinoma cells; NAG 1

Indexed keywords

CASPASE 3; COMPLEMENTARY DNA; CYCLOOXYGENASE 2; DEATH RECEPTOR 4; DEATH RECEPTOR 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SULINDAC SULFIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL POPULATION; CELL SPECIFICITY; CELL STRAIN; CELL TYPE; CONTROLLED STUDY; EVALUATION; FLUORESCENCE ACTIVATED CELL SORTING; GENE; GENE ACTIVITY; GENE FUNCTION; GENE INDUCTION; GENETIC TRANSFECTION; HEP 3 B CELL; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LIVER CELL CULTURE; NONHUMAN; NONSTEROIDAL ANTI INFLAMMATORY DRUG ACTIVATED GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOOXYGENASE 2; CYTOKINES; G1 PHASE; HUMANS; MEMBRANE PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; SULINDAC; TRANSFECTION;

EID: 33745808399     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-8160-x     Document Type: Article

References (31)

1. Kune GA, Kune S, Watson LF (1988) Colorectal cancer risk, chronic illnesses, operations and medications: case control results from the Melbourne Colorectal Cancer Study. Cancer Res 48:4399-4404
2. Baek SJ, Kim KS, Nixon JB, Wilson LG, Eling TE (2001) Cyclooxygenase inhibitors regulate the expression of a TGF-β superfamily member that has proapoptotic and antitumorigenic activities. Mol Pharmacol 59:901-908
3. Goel A, Chang DK, Ricciardiello L, Gasche C, Boland CR (2003) A novel mechanism for aspirin-mediated growth inhibition of human colon cancer cells. Clin Cancer Res 9:383-390
4. Hanif R, Pittas A, Feng Y et al (1996) Effects of nonsteroidal antiinflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway. Biochem Pharmacol 52:237-245
5. Zhang X, Morham SG, Langenbach R, Young DA (1999) Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. J Exp Med 190:451-459
6. Jang TJ, Kang HJ, Kim JR, Yang CH (2004) Nonsteroidal antiinflammatory drug activated gene (NAG-1) expression is closely related to death receptor-4 and -5 induction, which may explain sulindac sulfide induced gastric cancer cell apoptosis. Carcinogenesis 25:1853-1858
7. Tsujii M, DuBois RN (1995) Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83:493-501
8. Sun Y, Tang XM, Half E, Kuo MT, Sinicrope FA (2002) Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells. Cancer Res 62:6323-6328.
9. Hromas R, Hufford M, Sutton J, Xu D, Li Y, Lu L (1997) PLAB, a novel placental bone morphogenetic protein. Biochim Biophys Acta 1354:40-44
10. Lawton LN, Bonaldo MF, Jelenc PC et al (1997) Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta. Gene 203:17-26
11. Paralkar VM, Vail AL, Grasser WA et al (1998) Cloning and characterization of a novel member of the transforming growth factor-beta(bone morphogenetic protein family. J Biol Chem 273:13760-13767
12. Bootcov MR, Bauskin AR, Valenzuela SM et al (1997) MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proc Natl Acad Sci USA 94:11514-11519
13. Whitman M (1998) Smads and early developmental signaling by the TGF beta superfamily. Genes Dev 12:2445-2462
14. Lee DH, Yang Y, Lee SJ et al (2003) Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system. Cancer Res 63:4648-4655
15. Eberhart CE, Coffey RJ, Radhika A et al (1994) Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107:1183-1188
16. Lim HY, Joo HJ, Choi JH et al (2000) Increased expression of cyclooxygenase-2 protein in human gastric carcinoma. Clin Cancer Res 6:519-525
17. Shim V, Gauthier ML, Sudilovsky D et al(2003) Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium. Cancer Res 63:2347-2350
18. Yoshimatsu K, Altorki NK, Golijanin D et al (2001) Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer. Clin Cancer Res 7:2669-2674
19. Fujita H, Koshida K, Keller ET et al (2002) Cyclooxygenase-2 promotes prostate cancer progression. Prostate 53:232-240
20. 2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression. Proc Natl Acad Sci USA 101:591-596
21. Pai R, Nakamura T, Moon WS, Tarnawski AS (2003) Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors. FASEB J 17:1640-1647
22. Cao Y, Prescott SM (2002) Many actions of cyclooxygenase-2 in cellular dynamics and in cancer. J Cell Physiol 190:279-286
23. Tang X, Sun YJ, Half E, Kuo MT, Sinicrope FA (2002) Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells. Cancer Res 62:4903-4908
24. Nzeako UC, Guicciardi ME, Yoon JH, Bronk SF, Gores GJ (2002) COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells. Hepatology 35:552-559
25. Huang Y, He Q, Hillman MJ, Rong R, Sheikh MS (2001) Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells. Cancer Res 61:6918-6924
26. Cheng AS, Chan HL, Leung WK, Wong N, Johnson PJ, Sung JJ (2003) Specific COX-2 inhibitor, NS-398, suppresses cellular proliferation and induces apoptosis in human hepatocellular carcinoma cells. Int J Oncol 23:113-119
27. Yim HW, Jong HS, Kim TY, et al (2005) Cyclooxygenase-2 inhibits novel ginseng metabolite-mediated apoptosis. Cancer Res 65:1952-1960
28. Wakefield LM, Roberts AB (2002) TGF-beta signaling: positive and negative effects on tumorigenesis. Curr Opin Genet Dev 12:22-29
29. Welsh JB, Sapinoso LM, Su AI et al (2001) Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer. Cancer Res 61:5974-5978
30. Karan D, Kelly DL, Rizzino A, Lin MF, Batra SK (2002) Expression profile of differentially regulated genes during progression of androgen-independent growth in human prostate cancer cells. Carcinogenesis 23:967-976
31. Buckhaults P, Rago C, St Croix B et al (2001) Secreted and cell surface genes expressed in benign and malignant colorectal tumors. Cancer Res 61:6996-7001