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Volumn 70, Issue 17, 2005, Pages 7003-7006

A simple continuous flow microwave reactor

Author keywords

[No Author keywords available]

Indexed keywords

ENERGY EFFICIENCY; INFRARED DEVICES; MICROWAVE DEVICES; SENSORS; SYNTHESIS (CHEMICAL); TEMPERATURE CONTROL;

EID: 23644454820     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0510235     Document Type: Article
Times cited : (131)

References (55)
  • 1
    • 0037421895 scopus 로고    scopus 로고
    • (a) Adam, D. Nature 2003, 421, 571.
    • (2003) Nature , vol.421 , pp. 571
    • Adam, D.1
  • 16
    • 33645185305 scopus 로고    scopus 로고
    • http://www.cemsynthesis.com.
  • 24
    • 0037122699 scopus 로고    scopus 로고
    • 2O (2 mL) was irradiated at 150 °C in a sealed glass tube (150 W) for 10 min and evaporated in vacuo to give 2·HCl (151 mg, >98%). Comparable conductive heating procedures carried out at 150 °C in a sealed tube for 12 min, or at reflux for 30 min, gave thiazole 2·HCl (90% or 85%, respectively, by HPLC). For related hydrolysis experiments using conductive heating, see: (a) Houssin, R.; Pommery, J.; Salauen, M.-C.; Deweer, S.; Goossens, J.-F.; Chavatte, P.; Henichart, J.-P. J. Med. Chem. 2002, 45, 533.
    • (2002) J. Med. Chem. , vol.45 , pp. 533
    • Houssin, R.1    Pommery, J.2    Salauen, M.-C.3    Deweer, S.4    Goossens, J.-F.5    Chavatte, P.6    Henichart, J.-P.7
  • 52
    • 33645175353 scopus 로고    scopus 로고
    • note
    • The glass tube was filled with standard quartz sand, 40-100 mesh, suitable for use in chromatography. When aminodienonè 5 was irradiated in toluene (without acetic acid) in the presence and absence of sand in a sealed tube, no appreciable difference was observed (13% versus 5% conversion, respectively), indicating that the sand has a negligible (if any) effect on the cyclodehydration.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.