The Syndrome of Spastic Paresis

Neurological Disorders: Course and Treatment: Second Edition

Volumn , Issue , 2003, Pages 1247-1257

  Dietz, Volker ^a   Young, Robert R ^b  

^a BALGRIST UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33745781123     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012125831-3/50282-3     Document Type: Chapter

References (109)

1. Al-Khodairy A.T., Gobelet C., Rossier A.B. Has bot-ulinum toxin type A a place in the treatment of spasticity in spinal cord injury patients?. Spinal Cord 1998, 36:954-958.
2. Anderson T.P. Rehabilitation of patients with completed stroke. Krusen's Handbook of Physical Medicine and Rehabilitation 1982, 583-603. Saunders, Philadelphia. 3rd ed. F.J. Kottke, G.K. Stillwell, J.F. Lehmann (Eds.).
3. Auger R.G., Daube J.R., Gomez M.R., Lambert E.H. Hereditary form of sustained muscle activity of peripheral nerve origin causing generalized myokymia and muscle stiffness. Ann. Neurol. 1984, 15:13-21.
4. Barbeau H., Fung J. New experimental approaches in the treatment of spastic gait disorders. Movement Disorders in Children 1992, vol. 36:234-246. Karger, Basel. H. Forssberg, H. Hirschfeld (Eds.).
5. Barker R.A., Revesz T., Thom M., Marsden C.D., Brown P. Review of 23 patients affected by the stiff man syndrome: clinical subdivision into stiff trunk (man) syndrome, stiff limb syndrome, and progressive encephalomyelitis with rigidity. J. Neurol. Neurosurg. Psychiatry 1998, 65:633-640.
6. Bass B., Weinshenker B., Rice G.P., Noseworthy J.H., Cameron M.G., Hader W., Bouchard S., Ebers G.C. Tizanidine versus baclofen in the treatment of spasticity in patients with multiple sclerosis. Can. J. Neurol. Sci. 1988, 15:15-19.
7. Baumann J.U. Behandlung kindlicher spastischer Fuss-Deformitäten. Orthopäde 1986, 15:191-198.
8. Berger W., Horstmann G.A., Dietz V. Tension development and muscle activation in the leg during gait in spastic hemiparesis: The independence of muscle hypertonia and exaggerated stretch reflexes. J. Neurol. Neurosurg. Psychiatry 1984, 47:1029-1033.
9. Bes A., Eyssette M., Pierrot-Deseilligny E., Rohmer F., Warter J.M. A multi-centre, double-blind trial of tizanidine, a new antispastic agent, in spasticity associated with hemiplegia. Curr. Med. Res. Opin. 1988, 10:709-718.
10. Bhadra N., Peckham P.H. Peripheral nerve stimulation for restoration of motor function. J. Clin. Neurophysiol. 1997, 14:378-393.
11. Brown P., Marsden C.D. The stiff man and stiff man plus syndromes. J. Neurol. 1999, 246:648-652.
12. Brühlmeier M., Dietz V., Leenders K.L., Roelcke U., Missimer Y., Curt A. How does the brain deal with a spinal cord injury. Eur. J. Neurosci. 1998, 10:3918-3922.
13. Burke D., Ashby P. Are spinal "presynaptic" inhibitory mechanisms suppressed in spasticity?. J. Neurol. Sci. 1972, 15:321-326.
14. Carr L.J., Harrison L.M., Evans A.L., Stephens J.A. Patterns of central motor reorganization in hemiplegic cerebral palsy. Brain 1993, 116:1223-1247.
15. Chiara T., Carlos J., Martin D., Miller R., Nadeau S. Cold effect on oxygen uptake, perceived exertion, and spasticity in patients with multiple sclerosis. Arch. Phys. Med. Rehabil. 1998, 79:523-528.
16. Coffey J.R., Cahill D., Steers W., Park T.S., Ordia J., Meythaler J., Herman R., Shetter A.G., Levy R., Gill B., et al. Intrathecal baclofen for intractable spasticity of spinal origin: Results of a long-term multicenter study. J. Neurosurg. 1993, 78:226-232.
17. Corry I.S., Cosgrove A.P., Walsh E.G., McClean D., Graham H.K. Botulinum toxin A in the hemiplegic upper limb: a double blind trial. Dev. Med. Child. Neurol. 1997, 39:185-193.
18. Corston R.N., Johnson F., Godwin-Austen R.B. The assessment of drug treatment of spastic gait. J. Neurol. Neurosurg. Psychiatry 1981, 44:1035-1039.
19. Cutter N.C., Scott D.D., Johnson J.C., Whiteneck G. Gabapentin effect on spasticity in multiple sclerosis: a placebocontrolled, randomized trial. Arch. Phys. Med. Rehabil. 2000, 81:164-169.
20. Davidoff R.A. Antispasticity drugs: mechanisms of action. Ann. Neurol. 1985, 17:107-116.
21. Davis D., Jabbari B. Significant improvement of stiffperson syndrome after paraspinal injection of botulinum toxin A. Mov. Disord. 1993, 8:371-376.
22. Delwaide P.J. Human monosynaptic reflexes and presynaptic inhibition. New Developments in Electromyography and Clinical Neurophysiology 1973, vol. 3:508-522. Karger, Basel. J.E. Desmedt (Ed.).
23. Dietz V. Human neuronal control of functional movements. Interaction between central programs and afferent input. Physiol. Rev. 1992, 72:33-69.
24. Dietz V. Spasticity: exaggerated reflexes or movement disorder?. Movement Disorders in Children 1992, vol 36:225-233. Karger, Basel. H. Forssberg, H. Hirschfeld (Eds.).
25. Dietz V. Neurophysiology of gait disorders: present and future applications. Electroenceph. Clin. Neurophysiol. 1997, 103:333-355.
26. Dietz V. Supraspinal pathways and the development of muscle tone dysregulation. Dev. Med. Child. Neurol. 1999, 41:708-715.
27. Dietz V., Colombo G., Jensen L. Locomotor activity in spinal man. Lancet 1994, 344:1260-1263.
28. Dietz V., Trippel M., Berger W. Reflex activity and muscle tone during elbow movements in patients with spastic paresis. Ann. Neurol. 1991, 30:767-779.
29. Dinkel K., Meinck H.M., Jury K.M., Karges W., Richter W. Inhibition of gamma-aminobutyric acid synthesis by glutamic acid decarboxylase autoantibodies in stiff-man syndrome. Ann. Neurol. 1998, 44:194-201.
30. Dressnandt J., Conrad B. Lasting reduction of severe spasticity after ending chronic treatment with intrathecal baclofen. J. Neurol. Neurosurg. Psychiatry 1996, 60:168-173.
31. Duncan G.W., Shahani B.T., Young R.R. An evaluation of baclofen treatment for certain symptoms in patients with spinal cord lesions: a double-blind, cross-over study. Neurology 1976, 26:441-446.
32. Faist M., Ertel M., Berger W., Dietz V. Impaired modulation of quadriceps tendon jerk reflex during spastic gait. Differences between spinal and cerebral lesions. Brain 1999, 122:567-579.
33. Faist M., Mazevet D., Dietz V., Pierrot-Deseilligny E. A quantitative assessment of presynaptic inhibition of la afferents in spastics: Differences in hemiplegics and paraplegics. Brain 1994, 117:1449-1455.
34. Folli F., Solimena M., Cofiell R., Austoni M., Tallini G., Fassetta G., Bates D., Cartilidge N., Bottazzo G.F., Piccolo G., et al. Autoantibodies to a 128-kd synaptic protein in three women with the stiff-man syndrome and breast cancer. N. Engl. J. Med. 1991, 328:546-551.
35. Glenn M.B., Whyte J. The Practical Management of Spasticity in Children and Adults 1990, Lea & Febiger, Philadelphia, London.
36. Giuliani C.A. Dorsal rhizotomy for children with cerebral palsy: Support for concepts of motor control. Phys. Ther. 1991, 72:248-259.
37. Harryman S.E. Lower-extremity surgery for children with cerebral palsy: Physical therapy management. Phys. Ther. 1991, 72:16-24.
38. Hattab J.R. Review of European clinical trials with baclofen. Spasticity: Disordered Motor Control 1980, 71-85. Year Book, Chicago. R.G. Feldman, R.R. Young, W.P. Koella (Eds.).
39. Hiersemenzel L.P., Curt A., Dietz V. From spinal shock to spasticity. Neuronal adaptation to spinal cord injury. Neurology 2000, 54:1574-1582.
40. Hoogstraten M.C., van der Ploeg R.J., van der Burg W., Vreeling A., van Marle S., Minderhoud J.M. Tizanidine versus baclofen in the treatment of spasticity in multiple sclerosis patients. Acta Neurol. Scand. 1988, 77:224-230.
41. Hufschmidt A., Mauritz K.H. Chronic transformation of muscle in spasticity: A peripheral contribution to increased tone. J. Neurol. Neurosurg. Psychiatry 1985, 48:676-685.
42. Ibrahim I.K., Berger W., Trippel M., Dietz V. Stretchinduced electromyographic activity and torque in spastic elbow musles. Brain 1993, 116:971-989.
43. Jog M.S., Lambert C.D., Lang A.E. Stiff-person syndrome. Can. J. Neurol. Sci. 1992, 19:383-388.
44. Khanlou H., Eiger G. Long-term remission of refractory stiff-man syndrome after treatment with intravenous immunoglobulin. Mayo Clin. Proc. 1999, 74:1231-1232.
45. Kilgore K.L., Peckham P.H., Keith M.W., Thrope G.B., Wuolle K.S., Bryden A.M., Hart R.L. An implanted upperextremity neuroprosthesis. J. Bone. Joint. Surg. 1997, 79A:533-541.
46. Kwakkel G., Wagenaar R.C., Twisk J.W.R., Lankhorst G.J., Koetsier J.C. Intensity of leg and arm training after primary middle-cerebral-artery stroke: a randomized trial. Lancet 1999, 354:191-196.
47. Lacourse M.G., Lawrence K.E., Cohen M.J., Young R.R. Spinal cord injury. Exercise in Rehabilitation Medicine 1999, 267-292. Human Kinetics, Champaign, IL. W.R. Frontera, D.M. Dawson, D.M. Slovik (Eds.).
48. Laitinen L.V., Nilsson S., Fugl-Meyer A.R. Selective posterior rhizotomy for treatment of spasticity. J. Neurosurg. 1983, 58:895-899.
49. Lance J.W. Symposium synopsis. Spasticity: Disordered Motor Control 1980, 485-495. Year Book, Chicago. R.G. Feldman, R.R. Young, W.P. Koella (Eds.).
50. Landau W.M. Spasticity: What is it? What is it not?. Spasticity: Disordered Motor Control 1980, 17-24. Year Book, Chicago. R.G. Feldman, R.R. Young, W.P. Koella (Eds.).
51. Lapierre Y., Bouchard S., Tansey C., Gendron D., Barkas W.J., Francis G.S. Treatment of spasticity with tizanidine in multiple sclerosis. Can. J. Neurol. Sci. 1987, 14:513-517.
52. Latash M.L., Penn R.D., Carcos D.M., Gottlieb G.L. Short-term effects of intrathecal baclofen in spasticity. Exp. Neurol. 1989, 103:165-172.
53. Lee A., Patterson V. Double-blind study of L-threonine in patients with spinal spasticity. Acta Neurol. Scand. 1993, 88:334-338.
54. Levin M.F., Hui-Chan C.W. Relief of hemiparetic spasticity by TENS is associated with improvement in reflex and voluntary motor functions. Electroenceph. Clin. Neurophysiol. 1992, 85:131-142.
55. Levy L.M., Dalakas M.C., Floeter M.K. The stiffperson syndrome: an autoimmune disorder affecting neurotransmission of gamma-aminobutyric acid. Ann. Intern. Med. 1999, 131:522-530.
56. Lorish T.R., Thorstensson G., Howard F.M. Stiff man syndrome updated. Mayo Clin. Proc. 1989, 64:629-636.
57. Maurer M., Henn V., Dittrich A., Hofmann A. Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. Eur. Psychiat. Clin. Neurosci. 1990, 240:1-4.
58. McEvoy K.M. Stiff-man syndrome. Mayo Clin. Proc. 1991, 66:300-304.
59. McLaughlin J.F., Bjornson K.F., Astley S.J., Graubert C., Hays R.M., Roberts T.S., Price R., Temkin N. Selective dorsal rhizotomy: efficacy and safety in an investigator-masked randomized clinical trial. Dev. Med. Child. Neurol. 1998, 40:220-232.
60. Meinck H.-M., Schönle P.W., Conrad B. Cannabinoids on spasticity and ataxia in multiple sclerosis. J. Neurol. 1989, 236:120-122.
61. Mendell L.M. Modifiability of spinal synapses. Physiol. Rev. 1984, 64:260-324.
62. Meyler W.J., Bakker H., Kok J.J., Agoston S., Wesseling H. The effect of dantrolene sodium in relation to blood vessels in spastic patients after prolonged administration. J. Neurol. Neurosurg. Psychiatry 1981, 44:334-339.
63. Meythaler J.M., Guin-Renfroe S., Hadley M.N. Continuously infused intrathecal baclofen for spastic/dystonic hemiplegia. Am. J. Phys. Med. Rehabil. 1999, 78:247-254.
64. Ochs G., Struppler A., Meyerson B.A., Linderoth B., Gybels J., Gardner B.P., Teddy P., Jamous A., Weinmann P. Intrathecal baclofen for long-term treatment of spasticity: A multicentre study. J. Neurol. Neurosurg. Psychiatry 1989, 52:933-939.
65. O'Dwyer N.J., Ada L. Reflex hyperexcitability and muscle contracture in relation to spastic hypertonia. Curr. Opin. Neurol. 1996, 9:451-455.
66. Peacock W.J., Staudt L.A. Functional outcomes following selective posterior rhizotomy in children with cerebral palsy. J. Neurosurg. 1991, 74:380-385.
67. Pease W.S. Therapeutic electrical stimulation for spasticity: quantitative gait analysis. Am. J. Phys. Med. Rehab. 1998, 77:351-355.
68. Pedersen E. Clinical assessment and pharmacologic therapy of spasticity. Arch. Phys. Med. Rehabil. 1974, 55:344-356.
69. Penn R.D. Intrathecal baclofen for spasticity of spinal origin: Seven years of experience. J. Neurosurg. 1992, 77:236-240.
70. Penn R.D., Gottlieb G.L., Agarwal G.C. Cerebellar stimulation in man. Quantitative changes in spasticity. J. Neurosurg. 1978, 48:779-786.
71. Penn R.D., Savoy S.M., Corcos D., Latash M., Gottlieb G., Parke B., Kroin J.S. Intrathecal baclofen for severe spinal spasticity. N. Engl. J. Med. 1989, 320:1517-1521.
72. Popovic M.R., Keller T., Pappas I., Morari M., Dietz V. Grasping and walking protheses for stroke and spinal cord injured subjects. Proc. Am. Control Conf. 1999, 2:1243-1247.
73. Powers R.K., Campbell D.L., Rymer W.Z. Stretch reflex dynamics in spastic elbow flexor muscles. Ann. Neurol. 1989, 25:32-42.
74. Putty T.K., Shapiro S.A. Efficacy of dorsal longitudinal myelotomy in treating spinal spasticity: A review of 20 cases. J. Neurosurg. 1991, 75:397-401.
75. Russell W.R., Young R.R. Missile wounds of the parasagittal rolandic area. Modern Neurology 1969, 289-302. Little, Brown and Company, Boston. S. Locke (Ed.).
76. Saiz A., Graus F., Valldeoriola F., Valls-Sole J., Tolosa E. Stiff-leg syndrome: a focal form of stiff-man syndrome. Ann. Neurol. 1998, 43:400-403.
77. Sakamato T., Porter L.L., Asanuma H. Functional role of the sensory cortex in learning motor skills in cats. Brain Res. 1989, 503:258-264.
78. Schomburg E.D., Steffens H. The effect of DOPA and clonidine on reflex pathways from group II afferents to alphamotoneurons in the cat. Exp. Brain Res. 1988, 71:442-446.
79. Schurch B. Errors and limitations of the multimodality checking methods of defective spinal intrathecal pump system. Case report. Paraplegia 1993, 31:611-615.
80. Schurch B., Hauri D., Rodic B., Curt A., Meyer M., Rossier A.B. Botulinum-A toxin as a treatment of detrusor-sphincter dyssynergia: a prospective study in 24 spinal cord injury patients. J. Urol. 1996, 155:1023-1029.
81. Scott B.A., Weinstein Z., Chiteman R., Pulliam M.W. Intrathecal phenol and glycerin in metrizamide for treatment of intractable spasms in paraplegia. J. Neurosurg. 1985, 63:125-127.
82. Seib T.P., Price R., Reyes M.R., Lehmann J.F. The quantitative measurement of spasticity: Effect of cutaneous electrical stimulation. Arch. Phys. Med. Rehabil. 1994, 75:746-750.
83. Seif el Nasr M., Peruche B., Rossberg C., Mennel H.D., Krieglstein J. Neuroprotective effect of memantine demonstrated in vivo and in vitro. Eur. J. Pharmacol. 1990, 185:19-24.
84. Shefner J.M., Berman S.A., Sarkarati M., Young R.R. Recurrent inhibition is increased in patients with spinal cord injury. Neurology 1992, 42:2162-2168.
85. Sinkjaer T., Toft E., Larsen K., Andreassen S., Hansen H. Non-reflex and reflex mediated ankle joint stiffness in multiple sclerosis patients with spasticity. Muscle Nerve 1993, 16:69-76.
86. Skold C., Levi R., Seiger A. Spasticity after traumatic spinal cord injury: nature, severity and location. Arch. Phys. Med. Rehabil. 1999, 80:1548-1557.
87. Solimena M., De Camilli P. Autoimmunity to glutamic acid decarboxylase (GAD) in stiff-man syndrome and insulindependent diabetes mellitus. Trends Neurosci. 1991, 14:452-457.
88. Sonde L., Kalimo H., Fernaeus S.E., Viitanen M. Low TENS treatment on post-stroke paretic arm: a three-year followup. Clin. Rehabil. 2000, 14:14-19.
89. Steinbock P., Reiner A.M., Beauchamp R., Armstrong R.W., Cochrane D.D., Kestle J. A randomized clinical trial to compare selective posterior rhizotomy plus physiotherapy with physiotherapy alone in children with spastic diplegic cerebral plasy. Dev. Med. Child. Neurol. 1997, 39:178-184.
90. Stewart-Wynne E.G., Silbert P.L., Buffery S., Perlman D., Tan E. Intrathecal baclofen for severe spasticity: Five years experience. Clin. Exp. Neurol. 1991, 28:244-255.
91. Stien R., Nordal H.J., Oftedal S.I., Slettebo M. The treatment of spasticity in multiple sclerosis: A double-blind clinical trial of a new antispastic drug tizanidine compared with baclofen. Acta. Neurol. Scand. 1987, 75:190-194.
92. Stöhr M., Heckl R. Das Stiff-man-syndrome. Arch. Psychiat. Nervenkr. 1977, 223:171-180.
93. Thach W.T., Montgomery E.B. Motor systems. Neurobiology of Disease 1990, 168-196. Oxford Univ. Press, Oxford. A.L. Pearlman, R.C. Collins (Eds.).
94. Thilmann A.F., Fellows S.J., Garms E. The mechanism of spastic muscle hypertonus: Variation in reflex gain over the time course of spasticity. Brain 1991, 114:233-244.
95. Thompson P.D. Stiff muscles. J. Neurol. Neurosurg. Psychiatry 1993, 56:121-124.
96. Tsang K.L., Fong K.Y., Ho S.L. Localized neuromyotonia of neck muscles after radiotherapy for nasopharyngeal carcinoma. Mov. Disord. 1999, 14:1047-1949.
97. van den Berg J.S., van Engelen B.G., Boerman R.H., de Baets M.H. Acquired neuromyotonia: superiority of plasma exchange over high-dose intravenous human immunoglobulin. J. Neurol. 1999, 246:623-625.
98. Vincent A. Immunology of the neuromuscular junction and presynaptic nerve terminal. Curr. Opin. Neurol. 1999, 12:545-551.
99. Vincent A., Jacobson L., Plested P., Polizzi A., Tang T., Riemersma S., Newland C., Ghorazian S., Farrar J., MacLennan C., Willcox N., Beeson D., Newsom-Davis J. Antibodies affecting ion channel function in acquired neuromyotonia, in seropositive and seronegative myasthenia gravis, and in antibody-mediated arthrogryposis multiplex congenita. Ann. NY. Acad. Sci. 1998, 841:482-496.
100. Visintin M., Barbeau H. The effects of body weight support on the locomotor pattern of spastic paretic patients. Can. J. Neurol. Sci. 1989, 16:315-325.
101. Weingarden H.P., Zeilig G., Heruti R., Shemesh Y., Ohry A., Dar A., Katz D., Nathan R., Smith A. Hybrid functional electrical stimulation orthosis system for the upper limb: effects on spasticity in chronic stable hemiplegia. Am. J. Phys. Med. Rehabil. 1998, 77:276-281.
102. Wernig A., Müller S., Nanassy A., Cagol E Laufband therapy on rules of spinal locomotion is effective in spinal cord injured persons. Eur. J. Neurosci. 1995, 7:823-829.
103. Wiesendanger M., Chapman C.E., Marini G., Schorderet D. Experimental studies of dorsal cord stimulation in animal models of spasticity. Clinical Neurophysiology in Spasticity 1985, 205-219. Elsevier, Amsterdam. P.J. Delwaide, R.R. Young (Eds.).
104. Wright F.V., Sheil E.M., Drake J.M., Wedge J.H., Naumann S. Evaluation of selective dorsal rhizotomy for the reduction of spasticity in cerebral palsy: a randomized controlled trial. Dev. Med. Child. Neurol. 1998, 40:239-247.
105. Wuolle K.S., Van Doren C.L., Bryden A.M., Peckham P.H., Keith M.W., Kilgore K.L., Grill J.H. Satisfaction with and usage of a hand neuroprosthesis. Arch. Phys. Med. Rehabil. 1999, 80:206-213.
106. Yarkony G.M., Roth E.J., Cybulski G.R., Jaeger R.J. Neuromuscular stimulation in spinal cord injury. II: Prevention of secondary complications. Arch. Phys. Med. Rehabil. 1992, 73:195-200.
107. Young R.R., Delwaide P.J. Drug therapy: Spasticity. N. Engl. J. Med. 1981, 304:28-33.
108. Young R.R., Delwaide P.J. Drug therapy: Spasticity. N. Engl. J. Med. 1981, 304:96-99.
109. Young R.R. Spastic paresis. Multiple Sclerosis: Diagnosis, Medical Management, and Rehabilitation 2000, 299-306. Demos, New York. J.S. Burks, K.P. Johnson (Eds.).