Atmospheric pressure photoionization-mass spectrometry and atmospheric pressure chemical ionization-mass spectrometry of neurotransmitters

Journal of Mass Spectrometry

Volumn 41, Issue 6, 2006, Pages 781-789

  Kauppila, T J ^a   Nikkola, T ^a   Ketola, R A ^a   Kostiainen, R ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Amino acids; Atmospheric pressure chemical ionization; Atmospheric pressure photoionization; Catecholamines; Neurotransmitters; Steroids

Indexed keywords

AMINO ACIDS; ATMOSPHERIC PRESSURE; IONIZATION; NEGATIVE IONS; PHOTOIONIZATION; SOLVENTS;

ATMOSPHERIC PRESSURE CHEMICAL IONIZATION; ATMOSPHERIC PRESSURE PHOTOIONIZATION; CATECHOLAMINES; NEUROTRANSMITTERS; STEROIDS;

MASS SPECTROMETRY;

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; AMMONIUM HYDROXIDE; ANION; CATECHOLAMINE; CATION; DOPAMINE; ESTRADIOL; FORMIC ACID; METHANOL; NEUROSTEROID; NEUROTRANSMITTER; PRASTERONE; SOLVENT; WATER;

ARTICLE; ATMOSPHERIC PRESSURE; INTERMETHOD COMPARISON; IONIZATION; MASS SPECTROMETRY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS;

ATMOSPHERIC PRESSURE; NEUROTRANSMITTER AGENTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33745775407     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1034     Document Type: Article

References (48)

1. Schumacher M, Weill-Engerer S, Liere P, Robert F, Franklin RJM, Garcia-Segura LM, Lambert JJ, Mayo W, Melcangi RC, Parducz A, Suter U, Carelli C, Baulieu EE, Akwa Y. Steroid hormones and neurosteroids in normal and pathological aging of the nervous system. Prog. Neurobiol. 2003; 71: 3.
2. Mellon SH, Griffin LD. Neurosteroids: biochemistry and clinical significance. Trends Endocrinol. Metab. 2002; 13: 35.
3. Tsai TH. Separation methods used in the determination of choline and acetylcholine. J. Chromatogr. B Biomed. Sci. Appl. 2000; 747: 111.
4. Shah Ajit J, Crespi F, Heidbreder C. Amino acid neurotransmitters: separation approaches and diagnostic value. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2002; 781: 151.
5. Diallo S, Lecanu L, Greeson J, Papadopoulos V. A capillary gas chromatography/mass spectrometric method for the quantification of hydroxysteroids in human plasma. Anal. Biochem. 2004; 324: 123.
6. Vallee M, Rivera JD, Koob GF, Purdy RH, Fitzgerald RL. Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry. Anal. Biochem. 2000; 287: 153.
7. Vuorensola K, Siren H. Determination of urinary catecholamines with capillary electrophoresis after solid-phase extraction. J. Chromatogr., A 2000; 895: 317.
8. Vuorensola K, Kokkonen J, Siren H, Ketola RA. Optimization of capillary electrophoretic-electrospray ionization-mass spectrometric analysis of catecholamines. Electrophoresis 2001; 22: 4347.
9. Vuorensola K, Siren H, Karjalainen U. Determination of dopamine and methoxycatecholamines in patient urine by liquid chromatography with electrochemical detection and by capillary electrophoresis coupled with spectrophotometry and mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2003; 788: 277.
10. Vuorensola K, Siren H, Kostiainen R, Kotiaho T. Analysis of catecholamines by capillary electrophoresis and capillary electrophoresis- nanospray mass spectrometry. Use of aqueous and non-aqueous solutions compared with physical parameters. J. Chromatogr., A 2002; 979: 179.
11. Bergquist J, Silberring J. Identification of catecholamines in the immune system by electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 1998; 12: 683.
12. Hows MEP, Organ AJ, Murray S, Dawson LA, Foxton R, Heidbreder C, Hughes ZA, Lacroix L, Shah AJ. High-performance liquid chromatography/tandem mass spectrometry assay for the rapid high sensitivity measurement of basal acetylcholine from microdialyzates. J. Neurosci. Methods 2002; 121: 33.
13. Zhu Y, Wong PSH, Cregor M, Gitzen JF, Coury LA, Kissinger PT. In vivo microdialysis and reverse phase ion pair liquid chromatography/tandem mass spectrometry for the determination and identification of acetylcholine and related compounds in rat brain. Rapid Commun. Mass Spectrom. 2000; 14: 1695.
14. Qu J, Wang Y, Luo G, Wu Z, Yang C. Validated quantitation of underivatized amino acids in human blood samples by volatile ion-pair reversed-phase liquid chromatography coupled to isotope dilution tandem mass spectrometry. Anal. Chem. 2002; 74: 2034.
15. Song Y, Shenwu M, Dhossche DM, Liu Y-M. A capillary liquid chromatographic/tandem mass spectrometric method for the quantification of G-aminobutyric acid in human plasma and cerebrospinal fluid. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2005; 814: 295.
16. Li W, Rossi DT, Fountain ST. Development and validation of a semi-automated method for L-Dopa and dopamine in rat plasma using electrospray LC/MS/MS. J. Pharm. Biomed. Anal. 2000; 24: 325.
17. Kushnir MM, Urry FM, Frank EL, Roberts WL, Shushan B. Analysis of catecholamines in urine by positive-ion electrospray tandem mass spectrometry. Clin. Chem. 2002; 48: 323.
18. Chatman K, Hollenbeck T, Hagey L, Vallee M, Purdy R, Weiss F, Siuzdak G. Nanoelectrospray mass spectrometry and precursor ion monitoring for quantitative steroid analysis and attomole sensitivity. Anal. Chem. 1999; 71: 2358.
19. Liu S, Sjövall J, Griffiths WJ. Neurosteroids in rat brain: extraction, isolation, and analysis by nanoscale liquid chromatography- electrospray mass spectrometry. Anal. Chem. 2003; 75: 5835.
20. Bank RA, Jansen EJ, Beekman B, Te Koppele JM. Amino acid analysis by reverse-phase high-performance liquid chromatography: improved derivatization and detection conditions with 9-fluorenylmethyl chloroformate. Anal. Biochem. 1996; 240: 167.
21. Mengerink Y, Kutlan D, Toth F, Csampai A, Molnar-Perl I. Advances in the evaluation of the stability and characteristics of the amino acid and amine derivatives obtained with the O-Phthaldialdehyde/3-mercaptopropionic acid and O-Phthaldialdehyde/N-Acetyl-L-Cysteine reagents. High-performance liquid chromatography-mass spectrometry study. J. Chromatogr., A 2002; 949: 99.
22. Ikonomou MG, Blades AT, Kebarle P. Electrospray-ion spray: a comparison of mechanisms and performance. Anal. Chem. 1991; 63: 1989.
23. Shimada K, Mukai Y, Yago K. Studies on neurosteroids. VII. Characterization of pregnenolone, its sulfate and dehydroepiandrosterone in rat brains using liquid chromatography/mass spectrometry. J. Liq. Chromatogr. Relat. Technol. 1998; 21: 765.
24. Kwon JY, Moini M. Analysis of underivatized amino acid mixtures using high performance liquid chromatography/dual oscillating nebulizer atmospheric pressure microwave induced plasma ionization-mass spectrometry. J. Am. Soc. Mass Spectrom. 2001; 12: 117.
25. Ma D, Zhang J, Sugahara K, Ageta T, Nakayama K, Kodama H. Simultaneous determination of G-aminobutyric acid and glutamic acid in the brain of 3-mercaptopropionic acid-treated rats using liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. J. Chromatogr. B Biomed. Sci. Appl. 1999; 726: 285.
26. Robb DB, Covey TR, Bruins AP. Atmospheric pressure photoionization: an ionisation method for liquid chromatography-mass spectrometry. Anal. Chem. 2000; 72: 3653.
27. Syage JA, Evans MD, Hanold KA. Photoionization mass spectrometry. Am. Lab. 2000; 32: 24.
28. + formation in photoionization mass spectrometry. J. Am. Soc. Mass Spectrom. 2004; 15: 1521.
29. Kauppila TJ, Kuuranne T, Meurer EC, Eberlin MN, Kotiaho T, Kostiainen R. Atmospheric pressure photoionization. The ionization mechanism and the effect of the solvent on ionization of naphthalenes. Anal. Chem. 2002; 74: 5470.
30. Kauppila TJ, Kostiainen R, Bruins AP. Anisole, a New Dopant for atmospheric pressure photoionization-mass spectrometry of low proton affinity, low ionization energy compounds. Rapid Commun. Mass Spectrom. 2004; 18: 808.
31. De Jager LS, Perfetti GA, Diachenko GW. LC-UV and LC-MS analysis of food and drink products containing kava. Food Addit. Contam. 2004; 21: 921.
32. Moriwaki H, Ishitake M, Yoshikawa S, Miyakoda H, Alary J-F. Determination of polycyclic aromatic hydrocarbons in sediment by liquid chromatography- atmospheric pressure photoionization mass spectrometry. Anal. Sci. 2004; 20: 375.
33. Hanold KA, Fischer SM, Cormia PH, Miller CE, Syage JA. Atmospheric pressure photoionization. 1. General properties for LC/MS. Anal. Chem. 2004; 76: 2842.
34. Takino M, Daishima S, Nakahara T. Liquid chromatography/mass spectrometric determination of patulin in apple juice using atmospheric pressure photoionization. Rapid Commun. Mass Spectrom. 2003; 17: 1965.
35. Mol R, De Jong GJ, Somsen GW. Online capillary electrophoresis-mass spectrometry using dopant-assisted atmospheric pressure photoionization: setup and system performance. Electrophoresis 2005; 26: 146.
36. Nilsson SL, Andersson C, Sjöberg PJR, Bylund D, Petersson P, Jörntén-Karlsson M, Markides KE. Phosphate buffers in capillary electrophoresis/mass spectrometry using atmospheric pressure photoionization and electrospray ionization. Rapid Commun. Mass Spectrom. 2003; 17: 2267.
37. Hsieh Y, Merkle K, Wang G, Brisson J-M, Korfmacher WA. High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometric analysis for small molecules in plasma. Anal. Chem. 2003; 75: 3122.
38. Greig MJ, Bolaños B, Quenzer T, Bylund JMR. Fourier transform ion cyclotron resonance mass spectrometry using atmospheric pressure photoionization for high-resolution analyses of corticosteroids. Rapid Commun. Mass Spectrom. 2003; 17: 2763.
39. Leinonen A, Kuuranne T, Kostiainen R. Liquid chromatography-mass spectrometry in anabolic steroid analysis-optimization and comparison of three ionization techniques: ESI, APCI and APPI. J. Mass Spectrom. 2002; 37: 693.
40. Alary J-F. Comparative study: LC-MS/MS analysis of four steroid compounds using a new photoionization source and a conventional APCI source. In Proceedings of the 49th ASMS Conference on Mass Spectrometry and Allied Topics, Chicago, IL, May 27-31, 2001.
41. Alary J-F, Berthemy A, Tuong A, Uzabiaga M-F. Comparative LC-MS/MS analysis of four neurosteroid compounds and their acetyl-pentafluorobenzyl derivatives using photoionization ion source and a conventional atmospheric pressure chemical ionization source. Proceedings of the 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, June 3-7, 2002.
42. Kostiainen R, Kauppila T. In Modern Methods for Lipid Analysis by Liquid Chromatography/Mass Spectrometry and Related Techniques, Byrdwell WC (ed). AOCS Press: Champaign, Illinois, 2005; 472.
43. Rauha J-P, Vuorela H, Kostiainen R. Effect of eluent on the ionisation efficiency of flavonoids by ionspray, atmospheric pressure chemical ionisation and atmospheric pressure photoionisation mass spectrometry. J. Mass Spectrom. 2001; 36: 1269.
44. Kauppila TJ, Kotiaho T, Bruins AP, Kostiainen R. Negative ion atmospheric pressure photoionization. J. Am. Soc. Mass Spectrom. 2004; 15: 203.
45. Linstrom PJ, Mallard WG (eds). NIST Chemistry WebBook, NIST Standard Reference Database Number 69. National Institute of Standards and Technology: Gaithersburg, MD, 2001; 20899, (http://webbook.nist.gov).
46. Herlinger E, Jameson RF, Linert W. Spontaneous autoxidation of dopamine. J. Chem. Soc., Perkin Trans. 2 1995; 259.
47. Dunphy R, Burinsky DJ. Detection of choline and acetylcholine in a pharmaceutical preparation using high-performance liquid chromatography/ electrospray ionization mass spectrometry. J. Pharm. Biomed. Anal. 2003; 31: 905.
48. Liere P, Akwa Y, Weill-Engerer S, Eychenne B, Pianos A, Robel P, Sjövall J, Schumacher M, Baulieu EE. Validation of an analytical procedure to measure trace amounts of neurosteroids in brain tissue by gas chromatography-mass spectrometry. J. Chromatogr. B Biomed. Sci. Appl. 2000; 739: 301.