LC-UV and LC-MS analysis of food and drink products containing kava

Food Additives and Contaminants

Volumn 21, Issue 10, 2004, Pages 921-934

  de Jager, L S ^a   Perfetti, G A ^a   Diachenko, G W ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Food analysis; Kava; Kava lactones; LC MS; Piper methysticum

Indexed keywords

DEMETHOXYYANGONIN; DIHYDROKAWAIN; DIHYDROMETHYSTICIN; KAVA EXTRACT; KAWAIN; LACTONE; METHANOL; METHYSTICIN; YANGONIN;

ARTICLE; CACAO; CALIBRATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG STRUCTURE; FOOD ANALYSIS; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; REPRODUCIBILITY; SOLID PHASE EXTRACTION; TEA; ULTRAVIOLET RADIATION;

BEVERAGES; CHROMATOGRAPHY, LIQUID; DIETARY SUPPLEMENTS; FOOD ANALYSIS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; KAVA; LACTONES; PLANT EXTRACTS; PLANT ROOTS; SOLVENTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

PIPER METHYSTICUM;

EID: 10044248727     PISSN: 0265203X     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652030400010454     Document Type: Article

References (13)

1. Blumenthal, M., 2003, Herbs continue slide in mainstream market: sales down 14 percent. Herbalgram, 58, 71.
2. Blumenthal, M., Busse, W. R., Goldberg, A., Gruenwald, J., Hall, T., and Rister, R. (eds), 1998, The Complete German Commission E Monographs, Therapeutic Guide to Herbal Medicines (Austin, TX: American Botanical Council).
3. He, X., Lin, L., and Lian, L., 1997, Electrospray high performance liquid chromatography-mass spectrometry in phytochemical analysis of kava (Piper methysticum) extract. Planta Medica, 63, 70-74.
4. Kubátová, A., Miller, D. J., and Hawthorne, S. B., 2001, Comparison of subcritical water and organic solvents for extracting kava lactones from kava root. Journal of Chromatography, A, 923, 187-194.
5. Lechtenberg, M., Quandt, B., Kohlenberg, F., and Nahrstedt, A., 1999, Qualitative and quantitative micellar electrokinetic chromatography of kavalactones from dry extracts of Piper methysticum Forst and commercial drugs. Journal of Chromatography, A, 848, 457-464.
6. McKenna, D., Jones, K., and Hughes, K., 2002, Botanical Medicines. The Desk Reference for Major Herbal Supplements (New York: Hawthorn Herbal Press).
7. Schmidt, A., and Molnar, I., 2002, Computer-assisted optimization in the development of a high-performance liquid chromatographic method for the analysis of kava pyrones in Piper methysticum preparations. Journal of Chromatography, A, 948, 51-63.
8. Shao, Y., He, K., Zheng, B., and Zheng, Q., 1998, Reversed-phase high-performance liquid chromatographic method for quantitative analysis of the six major kavalactones in Piper methysticum. Journal of Chromatography, A, 825, 1-8.
9. Simeoni, P., and Lebot, V., 2002, Identification of factors determining kavalactone content and chemotype in kava (Piper methysticum Forst. f.). Biochemical Systematics and Ecology, 30, 413-424.
10. Singh, Y. N., and Blumenthal, M., 1997, Kava: an overview. Distribution, mythology, culture, chemistry and pharmacology of the South Pacific's most revered herb. Herbalgram, 39, 33-56.
11. Smith, R. M., Thakrar, H., Arowolo, T. A., and Shafi, A. A., 1984, High performance liquid chromatography of kava lactones from Piper Methysticum. Journal of Chromatography, 283, 303-308.
12. US Congress, 1994, Dietary Supplement Health and Education Act of 1994, 103rd Congress, second session (Public Law 103-417).
13. US Food and Drug Administration. Available online at: http://www.cfsan.fda.gov/~dms/addskava.html, accessed March 2004. Publication Date March 25, 2002.