메뉴 건너뛰기




Volumn 5, Issue 6, 2006, Pages 608-614

Inhibition of CD147 expression reduces tumor cell invasion in human prostate cancer cell line via RNA interference

Author keywords

CD147; Gene therapy; Invasion; Matrix metalloproteinase; Prostate cancer; RNA interference; Small interfering RNA

Indexed keywords

CD147 ANTIGEN; DOUBLE STRANDED DNA; GELATINASE A; GELATINASE B; MESSENGER RNA; SMALL INTERFERING RNA;

EID: 33745768853     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.5.6.2661     Document Type: Article
Times cited : (45)

References (59)
  • 2
    • 0030891731 scopus 로고    scopus 로고
    • Population-based study of long-term survival in patients with clinically localised prostate cancer
    • Lu-Yao GL, Yao SL. Population-based study of long-term survival in patients with clinically localised prostate cancer. Lancet 1997; 349:906-10.
    • (1997) Lancet , vol.349 , pp. 906-910
    • Lu-Yao, G.L.1    Yao, S.L.2
  • 3
    • 0029890280 scopus 로고    scopus 로고
    • Risk factors for progression in patients with prostate cancer treated with radical prostatectomy
    • Lerner SE, Blute ML, Zincke H. Risk factors for progression in patients with prostate cancer treated with radical prostatectomy. Semin Urol Oncol 1996; 14:12-21.
    • (1996) Semin Urol Oncol , vol.14 , pp. 12-21
    • Lerner, S.E.1    Blute, M.L.2    Zincke, H.3
  • 4
    • 0034817278 scopus 로고    scopus 로고
    • Long-term biochemical disease-free and cancer-specific survival following anatomic radical retropubic prostatectomy. The 15-year Johns Hopkins experience
    • Han M, Partin AW, Pound CR, Epstein JI, Walsh PC. Long-term biochemical disease-free and cancer-specific survival following anatomic radical retropubic prostatectomy. The 15-year Johns Hopkins experience. Urol Clin North Am 2001; 28:555-65.
    • (2001) Urol Clin North Am , vol.28 , pp. 555-565
    • Han, M.1    Partin, A.W.2    Pound, C.R.3    Epstein, J.I.4    Walsh, P.C.5
  • 5
    • 0036682025 scopus 로고    scopus 로고
    • Radical radiation for localized prostate cancer: Local persistence of disease results in a late wave of metastases
    • Coen JJ, Zietman AL, Thakral H, Shipley WU. Radical radiation for localized prostate cancer: Local persistence of disease results in a late wave of metastases. J Clin Oncol 2002; 20:3199-205.
    • (2002) J Clin Oncol , vol.20 , pp. 3199-3205
    • Coen, J.J.1    Zietman, A.L.2    Thakral, H.3    Shipley, W.U.4
  • 6
    • 0027813109 scopus 로고
    • PSA detected (clinical stage T1c or B0) prostate cancer: Pathological significant tumors
    • Oesterling JE, Suman VJ, Zinke H, Bostwick DG. PSA detected (clinical stage T1c or B0) prostate cancer: Pathological significant tumors. Urol Clin North Am 1993; 20:687-93.
    • (1993) Urol Clin North Am , vol.20 , pp. 687-693
    • Oesterling, J.E.1    Suman, V.J.2    Zinke, H.3    Bostwick, D.G.4
  • 8
    • 0025083071 scopus 로고
    • Critical factors in the biology of human cancer metastasis: Twenty-eighth G.H.A. Clowes memorial award lecture
    • Fidler IJ. Critical factors in the biology of human cancer metastasis: Twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res 1990; 50:6130-8.
    • (1990) Cancer Res , vol.50 , pp. 6130-6138
    • Fidler, I.J.1
  • 9
    • 0028795147 scopus 로고
    • The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily
    • Biswas C, Zhang Y, DeCastro R, Guo H, Nakamura T, Kataoka H, Nabeshima K. The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res 1995; 55:434-9.
    • (1995) Cancer Res , vol.55 , pp. 434-439
    • Biswas, C.1    Zhang, Y.2    DeCastro, R.3    Guo, H.4    Nakamura, T.5    Kataoka, H.6    Nabeshima, K.7
  • 10
    • 0027328322 scopus 로고
    • Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase
    • Kataoka H, DeCastro R, Zucker S, Biswas C. Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase. Cancer Res 1993; 53:3154-8.
    • (1993) Cancer Res , vol.53 , pp. 3154-3158
    • Kataoka, H.1    DeCastro, R.2    Zucker, S.3    Biswas, C.4
  • 11
    • 0031036521 scopus 로고    scopus 로고
    • Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells
    • Guo H, Zucker S, Gordon MK, Toole BP, Biswas C. Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells. J Biol Chem 1997; 272:24-7.
    • (1997) J Biol Chem , vol.272 , pp. 24-27
    • Guo, H.1    Zucker, S.2    Gordon, M.K.3    Toole, B.P.4    Biswas, C.5
  • 12
    • 0036605095 scopus 로고    scopus 로고
    • Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts
    • Kanekura T, Chen X, Kanzaki T. Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts. Int J Cancer 2002; 99:520-8.
    • (2002) Int J Cancer , vol.99 , pp. 520-528
    • Kanekura, T.1    Chen, X.2    Kanzaki, T.3
  • 15
    • 0036995757 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor-host cell communication
    • Lynch CC, Matrisian LM. Matrix metalloproteinases in tumor-host cell communication. Differentiation 2002; 70:561-73.
    • (2002) Differentiation , vol.70 , pp. 561-573
    • Lynch, C.C.1    Matrisian, L.M.2
  • 16
    • 0032714763 scopus 로고    scopus 로고
    • Expression of the extracellular matrix metalloproteinase inducer (EMMPRIN) and the matrix metalloproteinase-2 in bronchopulmonary and breast lesions
    • Caudroy S, Polette M, Tournier JM, Burlet H, Toole B, Zucker S, Birembaut P. Expression of the extracellular matrix metalloproteinase inducer (EMMPRIN) and the matrix metalloproteinase-2 in bronchopulmonary and breast lesions. J Histochem Cytochem 1999; 47:1575-80.
    • (1999) J Histochem Cytochem , vol.47 , pp. 1575-1580
    • Caudroy, S.1    Polette, M.2    Tournier, J.M.3    Burlet, H.4    Toole, B.5    Zucker, S.6    Birembaut, P.7
  • 17
    • 0035861597 scopus 로고    scopus 로고
    • The involvement of HAb18G/CD147 in regulation of store-operated calcium entry and metastasis of human hepatoma cells
    • Jiang JL, Zhou Q, Yu MK, Ho LS, Chen ZN, Chan HC. The involvement of HAb18G/CD147 in regulation of store-operated calcium entry and metastasis of human hepatoma cells. J Biol Chem 2001; 276:46870-7.
    • (2001) J Biol Chem , vol.276 , pp. 46870-46877
    • Jiang, J.L.1    Zhou, Q.2    Yu, M.K.3    Ho, L.S.4    Chen, Z.N.5    Chan, H.C.6
  • 18
    • 0036605095 scopus 로고    scopus 로고
    • Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts
    • Kanekura T, Chen X, Kanzaki T. Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts. Int J Cancer 2002; 99:520-28.
    • (2002) Int J Cancer , vol.99 , pp. 520-528
    • Kanekura, T.1    Chen, X.2    Kanzaki, T.3
  • 20
    • 0034892712 scopus 로고    scopus 로고
    • Molecular mechanism about lymphogen- ous metastasis of hepatocarcinoma cells in mice
    • Hou L, Li Y, Jia YH, Wang B, Xin Y, Ling MY, Lü S. Molecular mechanism about lymphogen- ous metastasis of hepatocarcinoma cells in mice. World J Gastroenterol 2001; 7:532-6.
    • (2001) World J Gastroenterol , vol.7 , pp. 532-536
    • Hou, L.1    Li, Y.2    Jia, Y.H.3    Wang, B.4    Xin, Y.5    Ling, M.Y.6    Lü, S.7
  • 21
  • 22
    • 0036675518 scopus 로고    scopus 로고
    • Fibroblasts promote breast cancer cell invasion by upregulating tumor matrix metalloproteinase-9 production
    • Wang TN, Albo D, Tuszynski GP. Fibroblasts promote breast cancer cell invasion by upregulating tumor matrix metalloproteinase-9 production. Surgery 2002; 132:220-5.
    • (2002) Surgery , vol.132 , pp. 220-225
    • Wang, T.N.1    Albo, D.2    Tuszynski, G.P.3
  • 24
    • 0344844479 scopus 로고    scopus 로고
    • Regulation of extracellular matrix metalloproteinase inducer and matrix metalloproteinase expression by amphiregulin in transformed human breast epithelial cells
    • Menashi S, Serova M, Ma L, Vignot S, Mourah S, Calvo F. Regulation of extracellular matrix metalloproteinase inducer and matrix metalloproteinase expression by amphiregulin in transformed human breast epithelial cells. Cancer Res 2003; 63:7575-80.
    • (2003) Cancer Res , vol.63 , pp. 7575-7580
    • Menashi, S.1    Serova, M.2    Ma, L.3    Vignot, S.4    Mourah, S.5    Calvo, F.6
  • 25
    • 0034652586 scopus 로고    scopus 로고
    • EMMPRIN (CD147), an inducer of matrix metalloproteinase synthesis, also binds interstitial collagenase to the tumor cell surface
    • Guo H, Li R, Zucker S, Toole BP. EMMPRIN (CD147), an inducer of matrix metalloproteinase synthesis, also binds interstitial collagenase to the tumor cell surface. Cancer Res 2000; 60:888-91.
    • (2000) Cancer Res , vol.60 , pp. 888-891
    • Guo, H.1    Li, R.2    Zucker, S.3    Toole, B.P.4
  • 27
    • 0037392052 scopus 로고    scopus 로고
    • Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells
    • Yang JM, Xu Z, Wu H, Zhu H, Wu X, Hait WN. Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells. Mol Cancer Res 2003; 1:420-7.
    • (2003) Mol Cancer Res , vol.1 , pp. 420-427
    • Yang, J.M.1    Xu, Z.2    Wu, H.3    Zhu, H.4    Wu, X.5    Hait, W.N.6
  • 28
    • 0035266353 scopus 로고    scopus 로고
    • Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions
    • Sun J, Hemler ME. Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions. Cancer Res 2001; 61:2276-81.
    • (2001) Cancer Res , vol.61 , pp. 2276-2281
    • Sun, J.1    Hemler, M.E.2
  • 31
    • 0033851302 scopus 로고    scopus 로고
    • Expression of EMMPRIN (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas
    • Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, Koono M, Wakisaka S. Expression of EMMPRIN (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas. Int J Cancer 2000; 88:21-7.
    • (2000) Int J Cancer , vol.88 , pp. 21-27
    • Sameshima, T.1    Nabeshima, K.2    Toole, B.P.3    Yokogami, K.4    Okada, Y.5    Goya, T.6    Koono, M.7    Wakisaka, S.8
  • 32
    • 0030884405 scopus 로고    scopus 로고
    • Expression of gelatinase B and the extracellular matrix metalloproteinase inducer EMMPRIN in benign and malignant pigment cell lesions of the skin
    • van den Oord JJ, Paemen L, Opdenakker G, de Wolf-Peeters C. Expression of gelatinase B and the extracellular matrix metalloproteinase inducer EMMPRIN in benign and malignant pigment cell lesions of the skin. Am J Pathol 1997; 151:665-70.
    • (1997) Am J Pathol , vol.151 , pp. 665-670
    • Van Den Oord, J.J.1    Paemen, L.2    Opdenakker, G.3    De Wolf-Peeters, C.4
  • 33
    • 0033998456 scopus 로고    scopus 로고
    • Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: Correlation with invasive growth of breast cancer
    • Dalberg K, Eriksson E, Enberg U, Kjellman M, Backdahl M. Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: Correlation with invasive growth of breast cancer. World J Surg 2000; 24:334-40.
    • (2000) World J Surg , vol.24 , pp. 334-340
    • Dalberg, K.1    Eriksson, E.2    Enberg, U.3    Kjellman, M.4    Backdahl, M.5
  • 34
    • 0036339170 scopus 로고    scopus 로고
    • EMMPRIN (CD147) is expressed in Hodgkin's lymphoma and anaplastic large cell lymphoma: An immunohistochemical study of 60 cases
    • Thorns C, Feller AC, Merz H. EMMPRIN (CD147) is expressed in Hodgkin's lymphoma and anaplastic large cell lymphoma: An immunohistochemical study of 60 cases. Anticancer Res 2002; 22:1983-6.
    • (2002) Anticancer Res , vol.22 , pp. 1983-1986
    • Thorns, C.1    Feller, A.C.2    Merz, H.3
  • 35
    • 1642483595 scopus 로고    scopus 로고
    • Caveolin-1 regulates matrix metalloproteinases-1 induction and CD147/EMMPRIN cell surface clustering
    • Tang W, Hemler ME. Caveolin-1 regulates matrix metalloproteinases-1 induction and CD147/EMMPRIN cell surface clustering. J Biol Chem 2004; 279:11112-8.
    • (2004) J Biol Chem , vol.279 , pp. 11112-11118
    • Tang, W.1    Hemler, M.E.2
  • 36
    • 4344668062 scopus 로고    scopus 로고
    • Links between CD147 function, glycosylation, and caveolin-1
    • Tang W, Chang SB, Hemler ME. Links between CD147 function, glycosylation, and caveolin-1. Mol Biol Cell 2004; 15:4043-50.
    • (2004) Mol Biol Cell , vol.15 , pp. 4043-4050
    • Tang, W.1    Chang, S.B.2    Hemler, M.E.3
  • 37
    • 0642277903 scopus 로고    scopus 로고
    • EMMPRIN (CD147), a cell surface regulator of matrix metalloproteinase production and function
    • Toole BP. EMMPRIN (CD147), a cell surface regulator of matrix metalloproteinase production and function. Curr Top Dev Biol 2003; 54:371-89.
    • (2003) Curr Top Dev Biol , vol.54 , pp. 371-389
    • Toole, B.P.1
  • 40
    • 0032443309 scopus 로고    scopus 로고
    • Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38
    • Lim M, Martinez T, Jablons D, Cameron R, Guo H, Toole B, Li JD, Basbaum C. Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38. FEBS Lett 1998; 441:88-92.
    • (1998) FEBS Lett , vol.441 , pp. 88-92
    • Lim, M.1    Martinez, T.2    Jablons, D.3    Cameron, R.4    Guo, H.5    Toole, B.6    Li, J.D.7    Basbaum, C.8
  • 41
    • 0037158892 scopus 로고    scopus 로고
    • Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway
    • Taylor PM, Woodfield RJ, Hodgkin MN, Pettitt TR, Martin A, Kerr DJ, Wakelam MJ. Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway. Oncogene 2002; 21:5765-72.
    • (2002) Oncogene , vol.21 , pp. 5765-5772
    • Taylor, P.M.1    Woodfield, R.J.2    Hodgkin, M.N.3    Pettitt, T.R.4    Martin, A.5    Kerr, D.J.6    Wakelam, M.J.7
  • 42
    • 17144422889 scopus 로고    scopus 로고
    • Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases
    • Tang Y, Nakada MT, Kesavan P, McCabe F, Millar H, Rafferty P, Bugelski P, Yan L. Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. Cancer Res 2005; 65:3193-9.
    • (2005) Cancer Res , vol.65 , pp. 3193-3199
    • Tang, Y.1    Nakada, M.T.2    Kesavan, P.3    McCabe, F.4    Millar, H.5    Rafferty, P.6    Bugelski, P.7    Yan, L.8
  • 43
    • 0034776130 scopus 로고    scopus 로고
    • cGMP-regulated storeoperated calcium entry in human hepatoma cells
    • Jiang JL, Yu MK, Chen ZN, Chan HC. cGMP-regulated storeoperated calcium entry in human hepatoma cells. Cell Biol Int 2001; 25:993-5.
    • (2001) Cell Biol Int , vol.25 , pp. 993-995
    • Jiang, J.L.1    Yu, M.K.2    Chen, Z.N.3    Chan, H.C.4
  • 44
    • 0036329807 scopus 로고    scopus 로고
    • New insights into the role of extracellular matrix during tumor onset and progression
    • Pupa SM, Menard S, Forti S, Tagliabue E. New insights into the role of extracellular matrix during tumor onset and progression. J Cell Physiol 2002; 92:259-67.
    • (2002) J Cell Physiol , vol.92 , pp. 259-267
    • Pupa, S.M.1    Menard, S.2    Forti, S.3    Tagliabue, E.4
  • 45
    • 3042845832 scopus 로고    scopus 로고
    • Expression and activity of matrix metalloproteinases-2 and -9 in serum, core needle biopsies and tissue specimens of prostate cancer patients
    • Sauer CG, Kappeler A, Spath M, Kaden JJ, Michel MS, Mayer D. Expression and activity of matrix metalloproteinases-2 and -9 in serum, core needle biopsies and tissue specimens of prostate cancer patients. Virchows Arch 2004; 444:518-26.
    • (2004) Virchows Arch , vol.444 , pp. 518-526
    • Sauer, C.G.1    Kappeler, A.2    Spath, M.3    Kaden, J.J.4    Michel, M.S.5    Mayer, D.6
  • 46
    • 0035000670 scopus 로고    scopus 로고
    • Proteases in invasion: Matrix metalloproteinases
    • Stetler-Stevenson WG, Yu AE. Proteases in invasion: Matrix metalloproteinases. Semin Cancer Biol 2001; 11:143-52.
    • (2001) Semin Cancer Biol , vol.11 , pp. 143-152
    • Stetler-Stevenson, W.G.1    Yu, A.E.2
  • 47
    • 0025230509 scopus 로고
    • Metalloproteinases and their inhibitors in matrix remodelling
    • Matrisian LM. Metalloproteinases and their inhibitors in matrix remodelling. Trends Genet 1990; 6:121-5.
    • (1990) Trends Genet , vol.6 , pp. 121-125
    • Matrisian, L.M.1
  • 48
    • 0033039398 scopus 로고    scopus 로고
    • An odyssey from breast to bone: Multi-step control of mammary metastases and osteolysis by matrix metalloproteinases
    • Lochter A, Bissell MJ. An odyssey from breast to bone: Multi-step control of mammary metastases and osteolysis by matrix metalloproteinases. APMIS 1999; 107:128-36.
    • (1999) APMIS , vol.107 , pp. 128-136
    • Lochter, A.1    Bissell, M.J.2
  • 51
    • 0032103978 scopus 로고    scopus 로고
    • Synthetic matrix metalloproteinase inhibitor, BB-94, inhibits the invasion of neoplastic human prostate cells in a mouse model
    • Knox JD, Bretton L, Lynch T, Bowden GT, Nagle RB. Synthetic matrix metalloproteinase inhibitor, BB-94, inhibits the invasion of neoplastic human prostate cells in a mouse model. Prostate 1998; 35:248-54.
    • (1998) Prostate , vol.35 , pp. 248-254
    • Knox, J.D.1    Bretton, L.2    Lynch, T.3    Bowden, G.T.4    Nagle, R.B.5
  • 52
    • 0031930324 scopus 로고    scopus 로고
    • Requirement for matrix metalloproteinase-9 (gelatinase B) expression in metastasis by murine prostate carcinoma
    • Sehgal G, Hua J, Bernhard EJ, Sehgal I, Thompson TC, Muschel RJ. Requirement for matrix metalloproteinase-9 (gelatinase B) expression in metastasis by murine prostate carcinoma. Am J Pathol 1998; 152:591-6.
    • (1998) Am J Pathol , vol.152 , pp. 591-596
    • Sehgal, G.1    Hua, J.2    Bernhard, E.J.3    Sehgal, I.4    Thompson, T.C.5    Muschel, R.J.6
  • 54
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002; 296:550-3.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 55
    • 0037022382 scopus 로고    scopus 로고
    • Stable suppression of gene expression by RNAi in mammalian cells
    • USA
    • Paddison PJ, Caudy AA, Hannon GJ. Stable suppression of gene expression by RNAi in mammalian cells. Proc Natl Acad Sci USA 2002; 99:1443-8.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 1443-1448
    • Paddison, P.J.1    Caudy, A.A.2    Hannon, G.J.3
  • 56
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • Paul CP, Good PD, Winer I, Engelke DR. Effective expression of small interfering RNA in human cells. Nat Biotechnol 2002; 20:505-8.
    • (2002) Nat Biotechnol , vol.20 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3    Engelke, D.R.4
  • 57
    • 0347904503 scopus 로고    scopus 로고
    • Inhibition of telomerase activity in human cancer cells by RNA interference
    • Koscioiek BA, Kaiantidis K, Tabler M, Rowley PT. Inhibition of telomerase activity in human cancer cells by RNA interference. Mol Cancer Ther 2003; 2:209-16.
    • (2003) Mol Cancer Ther , vol.2 , pp. 209-216
    • Koscioiek, B.A.1    Kaiantidis, K.2    Tabler, M.3    Rowley, P.T.4
  • 58
    • 0038265000 scopus 로고    scopus 로고
    • RNAi as a gene therapy approach
    • Caplen NJ. RNAi as a gene therapy approach. Exp Opin Biol Ther 2003; 3:575-86.
    • (2003) Exp Opin Biol Ther , vol.3 , pp. 575-586
    • Caplen, N.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.