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Volumn 2, Issue 3, 2006, Pages 280-285

Effects of sildenafil a phosphodiesterase 5 inhibitor on rat liver cell key enzymes of gluconeogenesis and glycogenolysis

Author keywords

CAMP; CGMP; Gluconeogenesis; Glycogenolysis; Liver

Indexed keywords

GLUCOSE; GLYCOGEN PHOSPHORYLASE; LIVER ENZYME; NITRIC OXIDE; PHOSPHODIESTERASE V INHIBITOR; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); SILDENAFIL;

EID: 33745751145     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2006.280.285     Document Type: Article
Times cited : (24)

References (41)
  • 1
    • 0041827014 scopus 로고    scopus 로고
    • Stimulation by theophylline and sildenafil of rat submandibular secretion of protein, epidermal growth factor and flow rate
    • Abdollahi, M. and B. Simaiee, 2003. Stimulation by theophylline and sildenafil of rat submandibular secretion of protein, epidermal growth factor and flow rate. Pharmacol. Res., 48: 445-449.
    • (2003) Pharmacol. Res. , vol.48 , pp. 445-449
    • Abdollahi, M.1    Simaiee, B.2
  • 2
    • 0346147023 scopus 로고    scopus 로고
    • Protection by sildenafil and theophylline of lead acetate-induced oxidative stress in rat submandibular gland and saliva
    • Abdollahi, M., F. Fooladian, B. Emami, K. Zafari and A. Bahreini-Moghadam, 2003a. Protection by sildenafil and theophylline of lead acetate-induced oxidative stress in rat submandibular gland and saliva. Hum. Exp. Toxicol., 22: 587-592.
    • (2003) Hum. Exp. Toxicol. , vol.22 , pp. 587-592
    • Abdollahi, M.1    Fooladian, F.2    Emami, B.3    Zafari, K.4    Bahreini-Moghadam, A.5
  • 3
    • 3042645473 scopus 로고    scopus 로고
    • A review on blood glucose variations and affecting parameters
    • Abdollahi, M., F. Soleimani and S. Kangarlou, 2003b. A review on blood glucose variations and affecting parameters. Middle East Pharmacy, 11: 6-10.
    • (2003) Middle East Pharmacy , vol.11 , pp. 6-10
    • Abdollahi, M.1    Soleimani, F.2    Kangarlou, S.3
  • 4
    • 0141505057 scopus 로고    scopus 로고
    • Effects of phosphodiesterase 3,4,5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and susceptibility to a mitochondrial toxin
    • Abdollahi, M., T.S. Chan, V. Subrahmanyam and P.J. O'Brien, 2003c. Effects of phosphodiesterase 3,4,5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and susceptibility to a mitochondrial toxin. Mol. Cell Biochem., 252: 205-211.
    • (2003) Mol. Cell Biochem. , vol.252 , pp. 205-211
    • Abdollahi, M.1    Chan, T.S.2    Subrahmanyam, V.3    O'Brien, P.J.4
  • 5
    • 3042561798 scopus 로고    scopus 로고
    • Hyperglycemia associated with increased hepatic glycogen phosphorylase and phosphoenolpyruvate carboxykinase in rats following subchronic exposure to malathion
    • Abdollahi, M., M. Donyavi, S., Pournourmohammadi and M. Saadat, 2004a. Hyperglycemia associated with increased hepatic glycogen phosphorylase and phosphoenolpyruvate carboxykinase in rats following subchronic exposure to malathion. Comp. Biochem. Physiol. C Toxicol. Pharmacol., 137: 343-347.
    • (2004) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.137 , pp. 343-347
    • Abdollahi, M.1    Donyavi, M.2    Pournourmohammadi, S.3    Saadat, M.4
  • 7
    • 33745746113 scopus 로고    scopus 로고
    • Protective effects of sildenafil and dipyridamol from lead-induced lipid peroxidation in perfused rat liver
    • Aghababaeian, R., M. Ghazi-Khansari, K. Abdi, F. Taghadosinejad and M. Abdollahi, 2005. Protective effects of sildenafil and dipyridamol from lead-induced lipid peroxidation in perfused rat liver. Intl. J. Phamacol., 1: 157-160.
    • (2005) Intl. J. Phamacol. , vol.1 , pp. 157-160
    • Aghababaeian, R.1    Ghazi-Khansari, M.2    Abdi, K.3    Taghadosinejad, F.4    Abdollahi, M.5
  • 8
    • 20444388662 scopus 로고    scopus 로고
    • Total antioxidant capacity and levels of epidermal growth factor and nitric oxide in blood and saliva of insulin-dependent diabetic patients
    • Astaneie, F., M. Afshari, A. Mojtahedi, S. Mostafalou, M.J. Zamani, B. Larijani, M. Abdollahi, 2005. Total antioxidant capacity and levels of epidermal growth factor and nitric oxide in blood and saliva of insulin-dependent diabetic patients. Arch. Med. Res., 36: 376-381.
    • (2005) Arch. Med. Res. , vol.36 , pp. 376-381
    • Astaneie, F.1    Afshari, M.2    Mojtahedi, A.3    Mostafalou, S.4    Zamani, M.J.5    Larijani, B.6    Abdollahi, M.7
  • 9
    • 27444444956 scopus 로고    scopus 로고
    • Alteration of glucose homeostasis by rolipram and milrinone but not sildenafil in rat primary hepatocytes culture
    • Atefi, M., S. Ghazanfari, S.N. Ostad, M.H. Ghahremani and M. Abdollahi, 2004. Alteration of glucose homeostasis by rolipram and milrinone but not sildenafil in rat primary hepatocytes culture. Prog. Med. Res., 2: 1-12.
    • (2004) Prog. Med. Res. , vol.2 , pp. 1-12
    • Atefi, M.1    Ghazanfari, S.2    Ostad, S.N.3    Ghahremani, M.H.4    Abdollahi, M.5
  • 10
    • 0035113190 scopus 로고    scopus 로고
    • Oxidative stress and nitric oxide related parameters in type II diabetes mellitus: Effects of glycemic control
    • Aydin, A., H. Orhan, A. Sayal, M. Ozata, G. Sahin and A. Isimer, 2001. Oxidative stress and nitric oxide related parameters in type II diabetes mellitus: Effects of glycemic control. Clin. Biochem., 34: 65-70.
    • (2001) Clin. Biochem. , vol.34 , pp. 65-70
    • Aydin, A.1    Orhan, H.2    Sayal, A.3    Ozata, M.4    Sahin, G.5    Isimer, A.6
  • 11
    • 0032445219 scopus 로고    scopus 로고
    • Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes
    • Ballard, S.A., C.J. Gingell, K. Tang, L.A. Turner, M.E. Price and A.M. Naylor, 1998. Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes. J. Urol., 159: 2164-2171.
    • (1998) J. Urol. , vol.159 , pp. 2164-2171
    • Ballard, S.A.1    Gingell, C.J.2    Tang, K.3    Turner, L.A.4    Price, M.E.5    Naylor, A.M.6
  • 12
    • 0024322304 scopus 로고
    • The allosteric transition of glycogen phosphorylase
    • Barford, D. and L.N. Johnson, 1989. The allosteric transition of glycogen phosphorylase. Nature, 340: 609-616.
    • (1989) Nature , vol.340 , pp. 609-616
    • Barford, D.1    Johnson, L.N.2
  • 14
    • 0032533162 scopus 로고    scopus 로고
    • Specific features of glycogen metabolism in the liver
    • Bollen, M., S. Keppens and W. Stalmans, 1998. Specific features of glycogen metabolism in the liver. Biochem. J., 336: 19-31.
    • (1998) Biochem. J. , vol.336 , pp. 19-31
    • Bollen, M.1    Keppens, S.2    Stalmans, W.3
  • 15
    • 0030725098 scopus 로고    scopus 로고
    • Differential regulation of nitric oxide synthase mRNA xpression by lipopolysaccharide and pro-inflammatory cytokines in fetal hepatocytes treated with cycloheximide
    • Casado, M., M.J. Diaz-Guerra, L. Bosca and P. Martin-Sanz, 1997. Differential regulation of nitric oxide synthase mRNA xpression by lipopolysaccharide and pro-inflammatory cytokines in fetal hepatocytes treated with cycloheximide. Biochem. J., 327: 819-823.
    • (1997) Biochem. J. , vol.327 , pp. 819-823
    • Casado, M.1    Diaz-Guerra, M.J.2    Bosca, L.3    Martin-Sanz, P.4
  • 16
    • 0031871503 scopus 로고    scopus 로고
    • The importance of nitric oxide in the cytokine-induced inhibition of glucose formation by cultured hepatocytes incubated with insulin, dexamethasone and glucagon
    • Ceppi, E.D. and M.A. Titheradge, 1998. The importance of nitric oxide in the cytokine-induced inhibition of glucose formation by cultured hepatocytes incubated with insulin, dexamethasone and glucagon. Arch. Biochem. Biophys., 349: 167-174.
    • (1998) Arch. Biochem. Biophys. , vol.349 , pp. 167-174
    • Ceppi, E.D.1    Titheradge, M.A.2
  • 17
    • 0014027543 scopus 로고
    • The enzymatic carboxylation of phosphoenolpyruvate. II. Purification and properties of liver mitochondrial phosphoenolpyruvate carboxykinase
    • Chang, H.C. and M.D. Lane, 1966. The enzymatic carboxylation of phosphoenolpyruvate. II. Purification and properties of liver mitochondrial phosphoenolpyruvate carboxykinase. J. Biol. Chem., 241: 2413-2420.
    • (1966) J. Biol. Chem. , vol.241 , pp. 2413-2420
    • Chang, H.C.1    Lane, M.D.2
  • 18
    • 10944237677 scopus 로고    scopus 로고
    • Inhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5′-AMP-activated protein kinase
    • Cidad, P., A. Almeida and J.P. Bolanos, 2004. Inhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5′-AMP-activated protein kinase. Biochem. J., 384: 629-636.
    • (2004) Biochem. J. , vol.384 , pp. 629-636
    • Cidad, P.1    Almeida, A.2    Bolanos, J.P.3
  • 20
    • 0017620771 scopus 로고
    • Molecular basis of insulin action
    • Czech, M.P., 1977. Molecular basis of insulin action. Ann. Rev. Biochem., 46: 359-384.
    • (1977) Ann. Rev. Biochem. , vol.46 , pp. 359-384
    • Czech, M.P.1
  • 21
    • 0000203434 scopus 로고    scopus 로고
    • Phosphodiesterase 4 inhibitors, structurally unrelated to rolipram, as promising agents for the treatment of asthma and other pathologies
    • Dal-Piaz, V. and M.P. Giovannoni, 2000. Phosphodiesterase 4 inhibitors, structurally unrelated to rolipram, as promising agents for the treatment of asthma and other pathologies. Eur. J. Med. Chem., 35: 463-480.
    • (2000) Eur. J. Med. Chem. , vol.35 , pp. 463-480
    • Dal-Piaz, V.1    Giovannoni, M.P.2
  • 22
    • 0035501248 scopus 로고    scopus 로고
    • Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone: A peroxisome proliferator-activated receptor-gamma (PPARgamma)-independent, antioxidant-related mechanism
    • Davies, G.F., R.L. Khandelwal, L. Wu, B.H. Juurlink and W.J. Roesler, 2001. Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone: A peroxisome proliferator-activated receptor-gamma (PPARgamma)-independent, antioxidant-related mechanism. Biochem. Pharmacol., 62: 1071-1079.
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 1071-1079
    • Davies, G.F.1    Khandelwal, R.L.2    Wu, L.3    Juurlink, B.H.4    Roesler, W.J.5
  • 23
    • 0036711553 scopus 로고    scopus 로고
    • New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: A role for the transcription factor sterol regulatory element binding protein-1c
    • Foufelle, F. And P. Ferré, 2002. New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: A role for the transcription factor sterol regulatory element binding protein-1c. Biochem. J., 366: 377-391.
    • (2002) Biochem. J. , vol.366 , pp. 377-391
    • Foufelle, F.1    Ferré, P.2
  • 24
    • 13644265626 scopus 로고    scopus 로고
    • Alterations in antioxidant power and levels of epidermal growth factor and nitric oxide in saliva of patients with inflammatory bowel diseases
    • Jahanshahi, G., V. Motavasel, A. Rezaie, A.A. Hashtroudi, N.E. Daryani and M. Abdollahi, 2004. Alterations in antioxidant power and levels of epidermal growth factor and nitric oxide in saliva of patients with inflammatory bowel diseases. Dig. Dis. Sci., 49: 1752-1757.
    • (2004) Dig. Dis. Sci. , vol.49 , pp. 1752-1757
    • Jahanshahi, G.1    Motavasel, V.2    Rezaie, A.3    Hashtroudi, A.A.4    Daryani, N.E.5    Abdollahi, M.6
  • 26
    • 0025195243 scopus 로고
    • Stimulation of prostaglandin E1 binding to human platelet membrane by insulin and the activation of adenylate cyclase
    • Khan, N.N. and A.K. Sinha 1990. Stimulation of prostaglandin E1 binding to human platelet membrane by insulin and the activation of adenylate cyclase. J. Biom. Chem., 265: 4976-4981.
    • (1990) J. Biom. Chem. , vol.265 , pp. 4976-4981
    • Khan, N.N.1    Sinha, A.K.2
  • 27
    • 23244448247 scopus 로고    scopus 로고
    • Sildenafil inhibits the formation of superoxide and the expression of gp47 NAD(P)H oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells
    • Koupparis, A.J., J.Y. Jeremy, S. Muzaffar, R. Persad and N. Shukla, 2005. Sildenafil inhibits the formation of superoxide and the expression of gp47 NAD(P)H oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells. BJU. Intl., 96: 423-427.
    • (2005) BJU. Intl. , vol.96 , pp. 423-427
    • Koupparis, A.J.1    Jeremy, J.Y.2    Muzaffar, S.3    Persad, R.4    Shukla, N.5
  • 28
    • 0014216022 scopus 로고
    • The kinetics of glycogen phosphorylases from brain and muscle
    • Lowry, O.H., D.W. Schulz and J.V. Passonneau, 1967. The kinetics of glycogen phosphorylases from brain and muscle. J. Biol. Chem., 242: 271-280.
    • (1967) J. Biol. Chem. , vol.242 , pp. 271-280
    • Lowry, O.H.1    Schulz, D.W.2    Passonneau, J.V.3
  • 30
    • 1642463419 scopus 로고    scopus 로고
    • T-1032, a cyclic GMP phosphodiesterase-5 inhibitor, acutely blocks physiologic insulin-mediated muscle haemodynamic effects and glucose uptake in vivo
    • Mahajan, H., S.M. Richards, S. Rattigan and M.G. Clark, 2003. T-1032, a cyclic GMP phosphodiesterase-5 inhibitor, acutely blocks physiologic insulin-mediated muscle haemodynamic effects and glucose uptake in vivo. Br. J. Pharmacol., 140: 1283-1291.
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 1283-1291
    • Mahajan, H.1    Richards, S.M.2    Rattigan, S.3    Clark, M.G.4
  • 32
    • 0032797852 scopus 로고    scopus 로고
    • Regulation of glucose production by the liver
    • Nordlie, R.C., J.D. Foster and A.J. Lange, 1999. Regulation of glucose production by the liver. Ann. Rev. Nutr., 19: 379-406.
    • (1999) Ann. Rev. Nutr. , vol.19 , pp. 379-406
    • Nordlie, R.C.1    Foster, J.D.2    Lange, A.J.3
  • 35
    • 23044512742 scopus 로고    scopus 로고
    • Effects of pentoxifylline on oxidative stress and levels of EGF and NO in blood of diabetic type-2 patients; a randomized, double-blind placebo-controlled clinical trial
    • Radfar, M., B. Larijani, M. Hadjibabaie, B. Rajabipour, A. Mojtahedi and M. Abdollahi, 2005. Effects of pentoxifylline on oxidative stress and levels of EGF and NO in blood of diabetic type-2 patients; a randomized, double-blind placebo-controlled clinical trial. Biomed. Pharmacoth., 59: 302-306.
    • (2005) Biomed. Pharmacoth. , vol.59 , pp. 302-306
    • Radfar, M.1    Larijani, B.2    Hadjibabaie, M.3    Rajabipour, B.4    Mojtahedi, A.5    Abdollahi, M.6
  • 36
    • 24044513942 scopus 로고    scopus 로고
    • A review on the role of antioxidants in the management of diabetes and its complications
    • Rahimi, R., S. Nikfar, B. Larijani and M. Abdollahi, 2005. A review on the role of antioxidants in the management of diabetes and its complications. Biomed. Pharmacother., 59: 365-373.
    • (2005) Biomed. Pharmacother. , vol.59 , pp. 365-373
    • Rahimi, R.1    Nikfar, S.2    Larijani, B.3    Abdollahi, M.4
  • 37
    • 27444445602 scopus 로고    scopus 로고
    • Alteration of rat hepatic glycogen phosphorylase and phosphoenolpyruvate carboxykinase activities by Satureja khuzestanica Jamzad essential oil
    • Saadat, M., S. Pournourmohammadi, M. Donyavi, R. Khorasani, G. Amin, A.N. Salehnia and M. Abdollahi, 2004. Alteration of rat hepatic glycogen phosphorylase and phosphoenolpyruvate carboxykinase activities by Satureja khuzestanica Jamzad essential oil. J. Pharm. Pharm. Sci., 7: 310-314.
    • (2004) J. Pharm. Pharm. Sci. , vol.7 , pp. 1310-1314
    • Saadat, M.1    Pournourmohammadi, S.2    Donyavi, M.3    Khorasani, R.4    Amin, G.5    Salehnia, A.N.6    Abdollahi, M.7
  • 38
    • 22144480608 scopus 로고    scopus 로고
    • Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation inhypercholesterolaemic rabbits
    • Shukla, N., R. Jones, R. Persad, G.D. Angelini and J.Y. Jeremy, 2005. Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation inhypercholesterolaemic rabbits. Eur. J. Pharmacol., 517: 224-31.
    • (2005) Eur. J. Pharmacol. , vol.517 , pp. 224-231
    • Shukla, N.1    Jones, R.2    Persad, R.3    Angelini, G.D.4    Jeremy, J.Y.5
  • 39
    • 0034009080 scopus 로고    scopus 로고
    • Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions
    • Soderling, S.H. and J.A. Beavo, 2000. Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions. Curr. Opin. Cell. Biol. Rev., 12: 174-179.
    • (2000) Curr. Opin. Cell. Biol. Rev. , vol.12 , pp. 174-179
    • Soderling, S.H.1    Beavo, J.A.2
  • 40
    • 0034130633 scopus 로고    scopus 로고
    • Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors
    • Souness, J.E., D. Aldous and C. Sargent, 2000. Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors. Immunopharmacol. Rev., 47: 127-162.
    • (2000) Immunopharmacol. Rev. , vol.47 , pp. 127-162
    • Souness, J.E.1    Aldous, D.2    Sargent, C.3


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