In vitro actions on human cancer cells and the liquid chromatography-mass spectrometry/mass spectrometry fingerprint of phytochemicals in rice protein isolate

Journal of Agricultural and Food Chemistry

Volumn 54, Issue 12, 2006, Pages 4482-4489

  Yu, Shanggong ^a   Fang, Nianbai ^a   Li, Qinglin ^a   Zhang, Jianxiang ^a   Luo, Hongfeng ^a   Ronis, Martin ^a   Badger, Thomas M ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Anticancer properties; Apoptosis; LC MS MS; Phytochemicals; Rice protein isolate (RPI)

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PROTEIN BAX; VEGETABLE PROTEIN;

APOPTOSIS; ARTICLE; BREAST TUMOR; CELL DIVISION; CHEMISTRY; DRUG EFFECT; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MULTIPLE MYELOMA; RICE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CELL DIVISION; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; HUMANS; MASS SPECTROMETRY; MULTIPLE MYELOMA; ORYZA SATIVA; PLANT PROTEINS;

EID: 33745747265     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf0605852     Document Type: Article

References (59)

1. World Cancer Research Fund and American Institute for Cancer Research, Eds. Patterns of diet and cancer. In Food, Nutrition and the Prevention of Cancer: A Global Perspective; American Institute for Cancer Research: Washington, DC, 1997; pp 20-52.
2. Lamartiniere, C. A.; Murrill, W. B.; Manzolillo, P. A.; Zhang, J. X.; Barnes, S.; Zhang, X.; Wei, H.; Brown, N. M. Genistein alters the ontogeny of mammary gland development and protects against chemically induced mammary cancer in rats. Proc. Soc. Exp. Biol. Med. 1998, 217, 358-364.
3. Adlercreutz, H.; Mazur, W. Phyto-oestrogens and Western diseases. Ann. Med. 1997, 29, 95-120.
4. Barnes, S.; Sfakianos, J.; Coward, L.; Kirk, M. Soy isoflavonoids and cancer prevention. Underlying biochemical and pharmacological issues. Adv. Exp. Med. Biol. 1996, 401, 87-100.
5. Bingham, S. A.; Atkinson, C.; Liggins, J.; Bluck, L.; Coward, A. Phyto-oestrogens: Where are we now? Br. J. Nutr. 1998, 79, 393-406.
6. Adlercreutz, C. H.; Goldin, B. R.; Gorbach, S. L.; Hockerstedt, K. A.; Watanabe, S.; Hamalainen, E. K.; Markkanen, M. H.; Makela, T. H.; Wahala, K. T.; Adlercreutz, T. Soybean phytoestrogen intake and cancer risk. J. Nutr. 1995, 125, 757S-770S.
7. Arliss, R. M.; Biermann, C. A. Do soy isoflavones lower cholesterol, inhibit atherosclerosis, and play a role in cancer prevention? Holistic Nursing Pract. 2002, 16, 40-48.
8. Badger, T. M.; Ronis, J. J.; Simmen, R. C. M.; Simmen, F. A. Soy protein isolate and protection against cancer. J. Am. Coll. Nutr. 2005, 24, 146S-149S.
9. Botting, K. J.; Young, M. M.; Pearson, A. E.; Harris, P. J.; Ferguson, L. R. Antimutagens in food plants eaten by Polynesians: Micronutrients, phytochemicals and protection against bacterial mutagenicity of the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline. Food Chem. Toxicol. 1999, 37, 95-103.
10. Kang, M. Y.; Choi, Y. H.; Nam, S. H. Inhibitory mechanism of colored rice bran extract against mutagenicity induced by chemical mutagen mitomycin C. Agric. Chem. Biotechnol. 1996, 39, 424-429.
11. Nam, S. H.; Kang, M. Y. In vitro inhibitory effect of colored rice bran extracts on carcinogenicity. Agric. Chem. Biotechnol. 1997, 40, 307-312.
12. Yasukawa, K.; Akihisa, T.; Kimura, Y.; Tamura, T.; Takido, M. Inhibitory effect of cycloartenol ferulate, a component of rice bran, on tumor promotion in two-stage carcinogenesis in mouse skin. Biol. Pharm. Bull. 1998, 21, 1072-1076.
13. Takenaka, S.; Takahashi, K. Enhancement of fecal excretion of poly-chlorinated biphenyls by the addition of rice bran fiber to the diet in rats. Chemosphere 1991, 22, 375-381.
14. Aoe, S.; Oda, T.; Tojima, T.; Tanaka, M.; Tatsumi, K.; Mizutani, T. Effects of rice bran hemicellulose on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in Fischer 344 rats. Nutr. Cancer 1993, 20, 41-49.
15. Takeshita, M.; Nakamura, S.; Makita, F.; Ohwada, S.; Miyamoto, Y.; Morishita, Y. Antitumor effect of RBS (rice bran saccharide) on ENNG-induced carcinogenesis. Biotherapy 1992, 4, 139-145.
16. Hayashi, Y.; Nishikawa, Y.; Mori, H.; Tamura, H.; Matsushita, Y.-I.; Matsui, T. Antitumour activity of (10E,12Z)-9-hydroxy-10,12-octadecadienoic acid from rice bran. J. Ferment. Bioeng. 1998, 86, 149-153.
17. Takeo, S.; Kado, H.; Yamamoto, H.; Kamimura, M.; Watanabe, N.; Uchida, K.; Mori, Y. Studies on an antitumor polysaccharide RBS derived from rice bran. II. Preparation and general properties of RON, an active fraction of RBS. Chem. Pharm. Bull. 1988, 36, 3609-3613.
18. Koide, T.; Kamei, H.; Hashimoto, Y.; Kojima, T.; Hasegawa, M. Antitumor effect of hydrolyzed'anthocyanin from grape rinds and red rice. Cancer Biother. Radiopharm. 1996, 11, 273-277.
19. Akihisa, T.; Yasukawa, K.; Yamaura, M.; Ukiya, M.; Kimura, Y.; Shimizu, N.; Arai, K. Triterpene alcohol and sterol ferulates from rice bran and their antiinflammatory effects. J. Agric. Food Chem. 2000, 48, 2313-2319.
20. Guardiola, F.; Codony, R.; Addis, P. B.; Rafecas, M.; Boatella, J. Biological effects of oxysterols: Current status. Food Chem. Toxicol. 1996, 34, 193-211.
21. Seetharamaiah, G. S.; Chandrasekhara, N. Studies on hypocholesterolemic activity of rice bran oil. Atherosclerosis 1989, 78, 219-224.
22. Sugano, M.; Tsuji, E. Rice bran oil and cholesterol metabolism. J. Nutr. 1997, 127, 521S-524S.
23. Nakayama, S.; Manabe, A.; Suzuki, J.; Sakamoto, K.; Inagaki, T. Comparative effects of two forms of gamma-oryzanol in different sterol compositions on hyperlipidemia induced by cholesterol diet in rats. Jpn. J. Pharmacol. 1987, 44, 135-144.
24. Morita, T.; Oh-hashi, A.; Takei, K.; Ikai, M.; Kasaoka, S.; Kiriyama, S. Cholesterol-lowering effects of soybean, potato and rice proteins depend on their low methionine contents in rats fed a cholesterol-free purified diet. J. Nutr. 1997, 127, 470-477.
25. Ni, W.; Tsuda, Y.; Takashima, S.; Sato, H.; Sato, M.; Imaizumi, K. Anti-atherogenic effect of soya and rice-protein isolate, compared with casein, in apolipoprotein E-deficient mice. Br. J. Nutr. 2003, 90, 13-20.
26. Morita, T.; Kiriyama, S. A rice protein isolate alters 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in female rats. J. Nutr. Sci. Vitaminol. 1996, 42, 325-337.
27. Hakkak, R.; Korourian, S.; Fletcher, T.; Ferguson, M.; Hale, K.; Parker, M.; Holder, D.; Ronis, M. J.; Rowlands, J. C.; Badger, T. M. Lifetime dietary rice protein isolate consumption protects against DMBA-Induced mammary tumors in rats. Proc. Am. Assoc. Cancer Res. 2002, 43, 823-824.
28. Morita, T.; Kiriyama, S. Mass production method for rice protein isolate and nutritional evaluation. J. Food Sci. 1993, 58, 1393-1397.
29. Fang, N.; Rowlands, J. C.; Casida, J. E. Anomalous structure - activity relationships of 13-homo-13-oxarotenoids and 13-homo-13-oxadehydrorotenoids. Chem. Res. Toxicol. 1997, 10, 853-858.
30. Campling, B. G.; Pym, J.; Galbraith, P. R.; Cole, S. P. C. Use of the MTT assay for rapid determination of chemosensitivity of human leukemic blast cells. Leuk. Res. 1988, 12, 823-831.
31. Vermes, I.; Haanen, C.; Steffens-Nakken, H.; Reutelingsperger, C. A novel assay for apoptosis: Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled Annexin V. J. Immunol. Methods 1995, 184, 39-51.
32. Badger, T. M.; Ronis, M. J. J.; Simmen, R. C. M.; Simmen, F. A. Soy protein isolate and protection against cancer. J. Am. Coll. Nutr. 2005, 24, 146S-149S.
33. Morgan, D. O. Principles of CDK regulation. Nature 1995, 374, 131-134.
34. Fang, N.; Yu, S.; Badger, T. M. LC-MS/MS analysis of lysophospholipids associated with soy protein isolate. J. Agric. Food Chem. 2003, 51, 6676-6682.
35. Rentel, C.; Strohschein, S.; Albert, K.; Bayer E. Silver-plated vitamins: A method of detecting tocopherols and carotenoids in LC/ESI-MS coupling. Anal. Chem. 1998, 70, 4394-4400.
36. Marinetti, G. V.; Cattieu, K. Composition of phospholipids of human leukocytes. Chem. Phys. Lipids 1982, 31, 169-177.
37. Portman, O. W.; Alexander, M. Lysophosphatidylcholine concentrations and metabolism in aortic intima plus inner media: Effect of nutritionally induced atherosclerosis. J. Lipid Res. 1969, 10, 158-165.
38. 31P NMR. J. Lipid Res. 2001, 42, 1501-1508.
39. Croset, M.; Brossard, N.; Polette, A.; Lagarde, M. Characterization of plasma unsaturated lysophosphatidylcholines in human and rat. Biochem. J. 2000, 345, 61-67.
40. Huang, M.; Graeler, M.; Shankar, G.; Spencer, J.; Goetzl, E. Lysophospholipid mediators of immunity and neoplasia. Biochim. Biophys. Acta 2002, 1582, 161-167.
41. Tigyi, G. Lysolipid mediators in cell signaling & disease. Biochim. Biophys. Acta 2002, 1582, VII.
42. Gräler, M. H.; Goetzl, E. Lysophospholipids and their G protein-coupled receptors in inflammation and immunity. Biochim. Biophys. Acta 2002, 1582, 168-174.
43. Sugiyama, S.; Kugiyama, K.; Ogata, N.; Doi, H.; Ota, Y.; Ohgushi, M.; Matsumura, T.; Oka, H.; Yasue, H. Biphasic regulation of transcription factor nuclear factor-KB activity in human endothelial cells by lysophosphatidylcholine through protein kinase C-mediated pathway. Arterioscler. Thromb. Vasc. Biol. 1998, 18, 568-576.
44. Maillard, V.; Bougnoux, P.; Ferrari, P.; Jourdan, M. L.; Pinault, M.; Lavillonniere, F. N-3 and N-6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case-control study in Tours, France. Int. J. Cancer 2002, 98, 78-83.
45. Mukutmoni-Norris, M.; Hubbard, N. E.; Erickson, K. L. Modulation of murine mammary tumor vasculature by dietary n-3 fatty acids in fish oil. Cancer Lett. 2000, 150, 101-109.
46. Liu, X. H.; Rose, D. P. Suppression of type IV collagenase in MDA-MB-435 human breast cancer cells by eicosapentaenoic acid in vitro and in vivo. Cancer Lett. 1995, 92, 21-26.
47. Rose, D. P.; Connolly, J. M. Effects of dietary omega-3 fatty acids on human breast cancer growth and metastases in nude mice. J. Natl. Cancer Inst. 1993, 85, 1743-1747.
48. Rose, D. P.; Connolly, J. M.; Rayburn, J.; Coleman, M. Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cells in nude mice. J. Natl. Cancer Inst. 1995, 87, 587-592.
49. Chajs, V.; Sattler, W.; Stranzl, A.; Kostner, G. M. Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: Relationship to peroxides and vitamin E. Breast Cancer Res. Treat. 1995, 34, 199-212.
50. Chamras, H.; Ardashian, A.; Heber, D.; Glaspy, J. A. Fatty acid modulation of MCF-7 human breast cancer cell proliferation, apoptosis and differentiation. J. Nutr. Biochem. 2002, 13, 711-716.
51. Grammatikos, S. I.; Subbaiah, P. V.; Victor, T. A.; Miller, W. M. N-3 and N-6 fatty acid processing and growth effects in neoplastic and noncancerous human mammary epithelial cell lines. Br. J. Cancer 1994, 70, 219-227.
52. Germain, E.; Chajes, V.; Cognault, S.; Lhuillery, C.; Bougnoux, P. Enhancement of doxorubicin cytotoxicity by polyunsaturated fatty acids in the human breast turnor cell line MDA-MB-231: Relationship to lipid peroxidation. Int. J. Cancer 1998, 75, 578-583.
53. Kachhap, S. K.; Dange, P. P.; Santani, R. H.; Sawant, S. S.; Ghosh, S. N. Effect of omega-3 fatty acid (docosahexanoic acid) on BRCA1 gene expression and growth in MCF-7 cell line. Cancer Biother. Radiopharm. 2001, 16, 257-263.
54. Noguchi, M.; Earashi, M.; Minami, M.; Konoshita, K.; Miyazaki, I. Effects of eicosapentaenoic and docosahexaenoic acid on cell growth and prostaglandin E and leukotriene B production by a human breast cancer cell line (MDA-MB-231). Oncology 1995, 52, 458-464.
55. Rose, D. P.; Connolly, J. M. Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture. Cancer Res. 1990, 50, 7139-7144.
56. Wang, M.; Liu, Y. E.; Ni, J.; Aygun, B.; Goldberg, I. D.; Shi, Y. E. Induction of mammary differentiation by mammary-derived growth inhibitor-related gene that interacts with an omega-3 fatty acid on growth inhibition of breast cancer cells. Cancer Res. 2000, 60, 6482-6487.
57. Yamamoto, D.; Kiyozuka, Y.; Adachi, Y.; Takada, H.; Hioki, K.; Tsubura, A. Synergistic action of apoptosis induced by eicosapentaenoic acid and TNP-470 on human breast cancer cells. Breast Cancer Res. Treat. 1999, 55, 149-160.
58. Kachhap, S. K.; Dange, P.; Nath Ghosh, S. Effect of omega-6 polyunsaturated fatty acid (linoleic acid) on BRCA1 gene expression in MCF-7 cell line. Cancer Lett. 2000, 154, 115-120.
59. Razanamahefa, L.; Prouff, S.; Bardon, S. Stimulatory effect of arachidonic acid on T-47D human breast cancer cell growth is associated with enhancement of cyclin D1 mRNA expression. Nutr. Cancer 2000, 38, 274-280.