Apoptosis of viral-infected airway epithelial cells limit viral production and is altered by corticosteroid exposure

Respiratory Research

Volumn 7, Issue , 2006, Pages

  Singhera, Gurpreet K ^a   Chan, Tiffany S ^a   Cheng, Jenny Y ^a   Vitalis, Timothy Z ^b   Hamann, Kimm J ^c   Dorscheid, Delbert R ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID DERIVATIVE; DEATH RECEPTOR 4; DEATH RECEPTOR 5; LIGAND; OVALBUMIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; VIRUS DNA; ANTIINFLAMMATORY AGENT; BUDESONIDE; TNFRSF10A PROTEIN, HUMAN; TNFRSF10B PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ASTHMA; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; DNA DETERMINATION; DRUG EXPOSURE; FEMALE; GUINEA PIG; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFECTION; RESPIRATORY TRACT INFLAMMATION; VIRUS INFECTION; VIRUS INHIBITION; VIRUS PARTICLE; WESTERN BLOTTING; ACUTE DISEASE; ADENOVIRIDAE; ADENOVIRUS INFECTION; ANIMAL; CHEMICALLY INDUCED; CHRONIC DISEASE; COMPLICATION; EPITHELIUM CELL; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PNEUMONIA; TRACHEA; VIRION; VIROLOGY;

ACUTE DISEASE; ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BUDESONIDE; CELLS, CULTURED; CHRONIC DISEASE; EPITHELIAL CELLS; FEMALE; GUINEA PIGS; OVALBUMIN; PNEUMONIA; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; TRACHEA; VIRION;

EID: 33745698679     PISSN: 1465993X     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-7-78     Document Type: Article

References (30)

1. Gern JE: Viral respiratory infection and the link to asthma. Pediatr Infect Dis J 2004, 23(1 Suppl):S78-86.
2. Wilson NM: Virus infections, wheeze and asthma. Paediatr Respir Rev 2003, 4(3):184-192.
3. Chuang YY, Chiu CH, Wong KS, Huang JG, Huang YC, Chang LY, Lin TY: Severe adenovirus infection in children. J Microbiol Immunol Infect 2003, 36(1):37-40.
4. Lyles DS: Cytopathogenesis and inhibition of host gene expression by RNA viruses. Microbiol Mol Biol Rev 2000, 64(4):709-724.
5. Kotelkin A, Prikhod'ko EA, Cohen JI, Collins PL, Bukreyev A: Respiratory syncytial virus infection sensitizes cells to apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand. J Virol 2003, 77(17):9156-9172.
6. Zhang HG, Xie J, Xu L, Yang P, Xu X, Sun S, Wang Y, Curiel DT, Hsu HC, Mountz JD: Hepatic DR5 induces apoptosis and limits adenovirus gene therapy product expression in the liver. J Virol 2002, 76(11):5692-5700.
7. Clarke P, Meintzer SM, Gibson S, Widmann C, Garrington TP, Johnson GL, Tyler KL: Reovirus-induced apoptosis is mediated by TRAIL. J Virol 2000, 74(17):8135-8139.
8. Barber GN: Host defense, viruses and apoptosis. Cell Death Differ 2001, 8(2):113-126.
9. Yamada K, Elliott WM, Brattsand R, Valeur A, Hogg JC, Hayashi S: Molecular mechanisms of decreased steroid responsiveness induced by latent adenoviral infection in allergic lung inflammation. J Allergy Clin Immunol 2002, 109(1):35-42.
10. Thomas LH, Sharland M, Friedland JS: Steroids fail to down-regulate respiratory syncytial virus-induced IL-8 secretion in infants. Pediatr Res 2002, 52(3):368-372.
11. Azevedo AM, Durigon EL, Okasima V, Queiroz DA, de Moraes-Vasconcelos D, Duarte AJ, Grumach AS: Detection of influenza, parainfluenza, adenovirus and respiratory syncytial virus during asthma attacks in children older than 2 years old. Allergol Immunopathol (Madr) 2003, 31(6):311-317.
12. Yamada K, Elliott WM, Hayashi S, Brattsand R, Roberts C, Vitalis TZ, Hogg JC: Latent adenoviral infection modifies the steroid response in allergic lung inflammation. J Allergy Clin Immunol 2000, 106(5):844-851.
13. Duriez PJ, Shah GM: Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death. Biochem Cell Biol 1997, 75(4):337-349.
14. Kim JS, Rabe KF, Magnussen H, Green JM, White SR: Migration and proliferation of guinea pig and human airway epithelial cells in response to tachykinins. Am J Physiol 1995, 269(1 Pt 1):L119-26.
15. Davidson DJ, Kilanowski FM, Randell SH, Sheppard DN, Dorin JR: A primary culture model of differentiated murine tracheal epithelium. Am J Physiol Lung Cell Mol Physiol 2000, 279(4):L766-78.
16. Dorscheid DR, Wojcik KR, Sun S, Marroquin B, White SR: Apoptosis of airway epithelial cells induced by corticosteroids. Am J Respir Crit Care Med 2001, 164(10 Pt 1):1939-1947.
17. Murakami P, McCaman MT: Quantitation of adenovirus DNA and virus particles with the PicoGreen fluorescent Dye. Anal Biochem 1999, 274(2):283-288.
18. Dakhama A, Hegele RG, Laflamme G, Israel-Assayag E, Cormier Y: Common respiratory viruses in lower airways of patients with acute hypersensitivity pneumonitis. Am J Respir Crit Care Med 1999, 159(4 Pt 1):1316-1322.
19. Strater J, Walczak H, Pukrop T, Von Muller L, Hasel C, Kornmann M, Mertens T, Moller P: TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections. Gastroenterology 2002, 122(3):659-666.
20. Koornstra JJ, Kleibeuker JH, van Geelen CM, Rijcken FE, Hollema H, de Vries EG, de Jong S: Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas. J Pathol 2003, 200(3):327-335.
21. Spierings DC, de Vries EG, Vellenga E, van den Heuvel FA, Koornstra JJ, Wesseling J, Hollema H, de Jong S: Tissue distribution of the death ligand TRAIL and its receptors. J Histochem Cytochem 2004, 52(6):821-831.
22. Lum JJ, Pilon AA, Sanchez-Dardon J, Phenix BN, Kim JE, Mihowich J, Jamison K, Hawley-Foss N, Lynch DH, Badley AD: Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l. J Virol 2001, 75(22):11128-11136.
23. Servet-Delprat C, Vidalain PO, Bausinger H, Manie S, Le Deist F, Azocar O, Hanau D, Fischer A, Rabourdin-Combe C: Measles virus induces abnormal differentiation of CD40 ligand-activated human dendritic cells. J Immunol 2000, 164(4):1753-1760.
24. Dorscheid DR, Low E, Conforti A, Shifrin S, Sperling AI, White SR: Corticosteroid-induced apoptosis in mouse airway epithelium: effect in normal airways and after allergen-induced airway inflammation. J Allergy Clin Immunol 2003, 111(2):360-366.
25. Ishida K, Kelly LJ, Thomson RJ, Beattie LL, Schellenberg RR: Repeated antigen challenge induces airway hyperresponsiveness with tissue eosinophilia in guinea pigs. J Appl Physiol 1989, 67(3):1133-1139.
26. Bensaude E, Turner JL, Wakeley PR, Sweetman DA, Pardieu C, Drew TW, Wileman T, Powell PP: Classical swine fever virus induces proinflammatory cytokines and tissue factor expression and inhibits apoptosis and interferon synthesis during the establishment of long-term infection of porcine vascular endothelial cells. J Gen Virol 2004, 85(Pt 4):1029-1037.
27. Papadopoulos NG, Papi A, Psarras S, Johnston SL: Mechanisms of rhinovirus-induced asthma. Paediatr Respir Rev 2004, 5(3):255-260.
28. Wark PA, Johnston SL, Bucchieri F, Powell R, Puddicombe S, Laza-Stanca V, Holgate ST, Davies DE: Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 2005, 201(6):937-947.
29. Grunberg K, Sharon RF, Sont JK, In 't Veen JC, Van Schadewijk WA, De Klerk EP, Dick CR, Van Krieken JH, Sterk PJ: Rhinovirusinduced airway inflammation in asthma: effect of treatment with inhaled corticosteroids before and during experimental infection. Am J Respir Crit Care Med 2001, 164(10 Pt 1):1816-1822.
30. Buckingham SC, Jafri HS, Bush AJ, Carubelli CM, Sheeran P, Hardy RD, Ottolini MG, Ramilo O, DeVincenzo JP: A randomized, double-blind, placebo-controlled trial of dexamethasone in severe respiratory syncytial virus (RSV) infection: effects on RSV quantity and clinical outcome. J Infect Dis 2002, 185(9):1222-1228.