New 2′,6′-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique μ-opioid receptor ligands

Journal of Medicinal Chemistry

Volumn 49, Issue 13, 2006, Pages 3990-3993

  Ballet, Steven ^a   Salvadori, Severo ^b   Trapella, Claudio ^b   Bryant, Sharon D ^c   Jinsmaa, Yunden ^c   Lazarus, Lawrence H ^c   Negri, Lucia ^d   Giannini, Elisa ^d   Lattanzi, Roberta ^d   Tourwé, Dirk ^a   Balboni, Gianfranco ^b,e  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITY OF FERRARA   (Italy)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2',6' DIMETHYLTYROSINE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; BENZAZEPINE DERIVATIVE; DRUG DERIVATIVE; GLYCINE; LIGAND; NARCOTIC ANALGESIC AGENT; PEPTIDE;

ARTICLE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; IC 50; LIGAND BINDING; REACTION ANALYSIS; RECEPTOR AFFINITY; ANIMAL; CHEMISTRY; DRUG EFFECT; DRUG POTENTIATION; GUINEA PIG; IN VITRO STUDY; INNERVATION; METABOLISM; MOLECULAR MIMICRY; MUSCLE CONTRACTION; MYENTERIC PLEXUS; PHYSIOLOGY; RAT; SMOOTH MUSCLE; SPRAGUE DAWLEY RAT; STRUCTURE ACTIVITY RELATION; SYNAPTOSOME; SYNTHESIS;

ANALGESICS, OPIOID; ANIMALS; BENZAZEPINES; GLYCINE; GUINEA PIGS; LIGANDS; MOLECULAR MIMICRY; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYENTERIC PLEXUS; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPTOSOMES;

EID: 33745678483     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0603264     Document Type: Article

References (23)

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