Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: Monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A2

Acta Crystallographica Section D: Biological Crystallography

Volumn 62, Issue 7, 2006, Pages 717-724

  Sekar, K ^a   Yogavel, M ^b   Kanaujia, Shankar Prasad ^a   Sharma, Alok ^a   Velmurugan, D ^b   Poi, M J ^c   Dauter, Z ^d   Tsai, M D ^c,e  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b UNIVERSITY OF MADRAS   (India)

^c OHIO STATE UNIVERSITY   (United States)

^d ARGONNE NATIONAL LABORATORY   (United States)

^e GENOMICS RESEARCH CENTER   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; MUTANT PROTEIN; PHOSPHOLIPASE A; PHOSPHOLIPASE A2 ALPHA; PHOSPHOLIPASE A2-ALPHA; PHOSPHOLIPID; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BINDING SITE; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CRYSTALLIZATION; ENZYMOLOGY; GENETICS; HYDROGEN BOND; HYDROLYSIS; ISOLATION AND PURIFICATION; METHODOLOGY; MISSENSE MUTATION; PANCREAS; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; SWINE; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CALCIUM; CATTLE; COMPUTER SIMULATION; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; HYDROLYSIS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; MUTATION, MISSENSE; PANCREAS; PHOSPHOLIPASES A; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SWINE;

BOS TAURUS;

EID: 33745678022     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444906014855     Document Type: Article

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