Structures of the catalytic site mutants D99A and H48Q and the calcium-loop mutant D49E of phospholipase A2

Acta Crystallographica Section D: Biological Crystallography

Volumn 55, Issue 2, 1999, Pages 443-447

  Sekar, K ^a,b   Biswas, R ^a   Li, Y ^a   Tsai, M D ^a   Sundaralingam, M ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; PHOSPHOLIPASE A;

ANIMAL; ARTICLE; CATTLE; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; HYDROGEN BOND; MUTATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; CALCIUM; CATALYTIC DOMAIN; CATTLE; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MUTATION; PHOSPHOLIPASES A;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0033082064     PISSN: 09074449     EISSN: None     Source Type: Journal    
DOI: 10.1107/S0907444998013699     Document Type: Article

References (20)

1. Bernstein, F. C., Koetzle, T. F., Williams, G. J. B., Meyer, E. F. Jr, Brice, M. D., Rogers, J. R., Kennard, O., Shimanouchi, T. & Tasumi, M. J. (1977). J. Mol. Biol. 112, 535-542.
2. Brünger, A. T. (1992a). Nature (London), 355, 472-474.
3. Brünger, A. T. (1992b). X-PLOR Version 3.1. A System for X-ray Crystallography and NMR. New Haven, Connecticut: Yale University Press.
4. Davidson, F. F & Dennis, E. A. (1990). J. Mol. Evol. 31, 228-238.
5. Dijkstra, B. W., Drenth, J. & Kalk, K. H. (1981). Nature (London), 289, 604-606.
6. Fujinaga, M. & James, M. N. (1987). J. Mol. Biol. 195(2), 373-396.
7. Jones, T. A. (1985). Methods Enzymol. 115, 157-171.
8. Kumar, A., Sekharudu, Y. C, Ramakrishnan, B., Dupureur, C. M., Zhu, H., Tsai, M.-D. & Sundaralingam, M. (1994). Protein Sci. 3, 2082-2088.
9. Laskowski, R. A., MacArthur, M. W., Moss, D. S., Thornton, J. M. (1993). J. Appl. Cryst. 26, 283-291.
10. Li, Y. & Tsai, M.-D. (1993). J. Am. Chem. Soc. 115, 8523-8526.
11. Li, Y., Yu, B.-Z., Zhu, H., Jain, M. K. & Tsai, M.-D. (1994). Biochemistry, 33, 14714-14722.
12. Luzzati, V. (1952). Acta Cryst. 5, 802-807.
13. Ramakrishnan, C. & Ramachandran, G. N. (1965). Biophys. J. 5, 909-933.
14. Scott, D. L., White, S. P., Otwinowski, Z., Yuan, W., Gelb, M. H. & Sigler, P. B. (1990). Science, 250, 1541-1546.
15. Sekar, K., Eswaramoorthy, S., Jain, M. K. & Sundaralingam, M. (1997). Biochemistry, 36, 14186-14191.
16. Sekar, K., Sekharudu, Y. C., Tsai, M.-D. & Sundaralingam, M. (1998). Acta Cryst. D54, 342-346.
17. Sekar, K. & Sundaralingam, M. (1999). Acta Cryst. D55, 46-50.
18. Sekar, K., Yu, B.-Z., Rogers, J., Lutton, J., Liu, X., Chen, X., Tsai, M.-D., Jain, M. K. & Sundaralingam, M. (1997). Biochemistry, 36, 3101-3114.
19. Sprang, S., Standing, T., Fletterick, R. J., Stroud, R. M., Finer-Moore, J., Xuong, N.-H., Hamlin, R., Rutter, W. J. & Craik, C. S. (1987). Science, 237, 905-909.
20. Teplyakov, A. V., Kuranova, I. P., Harutyunyan, E. H., Vainshtein, B. K., Frommel, C., Hohne, W. I. & Wilson, K. S. (1990). J. Mol. Biol. 214, 262-269.