Alteration of an essential NK cell signaling pathway by low doses of tributyltin in human natural killer cells

Toxicology

Volumn 224, Issue 3, 2006, Pages 229-237

  Aluoch, Aloice O ^a   Odman Ghazi, Sabah O ^a   Whalen, Margaret M ^a  

^a TENNESSEE STATE UNIVERSITY   (United States)

Author keywords

MAP kinase kinases; MAP kinases; NK cells; Protein tyrosine kinases; Tributyltin

Indexed keywords

FOCAL ADHESION KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; TRIBUTYLTIN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DATA ANALYSIS; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; EXPOSURE VARIABLE; FEMALE; HUMAN; HUMAN CELL; IMMUNOCYTOTOXICITY; IMMUNOMODULATION; LOW DRUG DOSE; MALE; NATURAL KILLER T CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; TOXICOKINETICS; UPREGULATION;

BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLAVONOIDS; HUMANS; K562 CELLS; KILLER CELLS, NATURAL; MALE; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE KINASE 3; MAP KINASE KINASE 6; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TIME FACTORS; TRIALKYLTIN COMPOUNDS; WATER POLLUTANTS;

EID: 33745654069     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.05.002     Document Type: Article

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