Clinical doses of amikacin provide more effective suppression of the human CFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model

Journal of Molecular Medicine

Volumn 84, Issue 7, 2006, Pages 573-582

  Du, Ming ^a,c   Keeling, Kim M ^a,c   Fan, Liming ^a,c   Liu, Xiaoli ^a,c   Kovaçs, Timea ^b,c   Sorscher, Eric ^b,c   Bedwell, David M ^a,c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; COMPLEMENTARY DNA; FORSKOLIN; GENTAMICIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CFTR G542X TRANSGENE; CONTROLLED STUDY; CYSTIC FIBROSIS; GENE MUTATION; HEARING LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; KIDNEY INJURY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; SHORT CIRCUIT CURRENT; STOP CODON; TRANSGENE; TRANSGENIC MOUSE;

AMIKACIN; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CODON, NONSENSE; CYCLIC AMP; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENTAMICINS; HUMANS; INTESTINES; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROTEIN BIOSYNTHESIS;

EID: 33745628041     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-006-0045-5     Document Type: Article

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