Prediction of function divergence in protein families using the substitution rate variation parameter alpha

Molecular Biology and Evolution

Volumn 23, Issue 7, 2006, Pages 1406-1413

  Abhiman, Saraswathi ^a   Daub, Carsten O ^a   Sonnhammer, Erik L L ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adaptive evolution; Alpha parameter; Enzyme; Function shift; Gamma distribution; Protein evolution; Protein function; Protein subfamily; Substitution rates

Indexed keywords

ACCURACY; ALPHA SHIFT MEASURE; AMINO ACID SUBSTITUTION; ANALYTIC METHOD; ARTICLE; ENZYME SPECIFICITY; GENE SEQUENCE; GENETIC CONSERVATION; GENOME; LINEAR SYSTEM; MEASUREMENT; MOLECULAR EVOLUTION; PHYLOGENETIC TREE; PREDICTION; PROTEIN FAMILY; PROTEIN FUNCTION; SUBSTITUTION RATE VARIATION;

ALGORITHMS; AMINO ACID SUBSTITUTION; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; PHYLOGENY; PROTEINS; REPRODUCIBILITY OF RESULTS; SEQUENCE ALIGNMENT; VARIATION (GENETICS);

EID: 33745626732     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msl002     Document Type: Article

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