A simple covarion-based approach to analyse nucleotide substitution rates

Journal of Evolutionary Biology

Volumn 15, Issue 4, 2002, Pages 588-594

  Siltberg, J ^a   Liberles, D A ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Adaptive evolution; Bioinformatics; Gene sequence; Molecular evolution; Protein function

Indexed keywords

ADAPTATION; EVOLUTION; GENETIC ANALYSIS; PRIMATE;

GORILLA GORILLA; MAMMALIA; PRIMATES;

EID: 0036313499     PISSN: 1010061X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1420-9101.2002.00416.x     Document Type: Article

References (22)

1. Functional inferences from reconstructed evolutionary biology involving rectified databases - An evolutionarily grounded approach to functional genomics
2. Post genomic science: Converting primary sequence into physiological function
3. Identification of a placental enhancer for the human leptin gene
4. Large scale search for genes on which positive selection may operate
5. Toward defining the course of evolution: Minimum change for a specific tree topology
6. Function-structure analysis of proteins using covarion-based evolutionary approaches: Elongation factors
7. Darwin v. 2.0: An interpreted computer language for the biosciences
8. Punctuated equilibrium comes of age
9. Statistical methods for testing functional divergence after duplication
10. Maximum-likelihood approach for gene family evolution under functional divergence
11. The long terminal repeat of an endogenous retrovirus induces alternative splicing and encodes an additional carboxy-terminal sequence in the human leptin receptor
12. Probablistic reconstruction of ancestral protein sequences
13. A new method for estimating synonymous and nonsynonymous rates of nucleotide substitution considering the relative likelihood of nucleotide and codon changes
14. Evaluation of methods for determinarion of a reconstructed history of gene sequence evolution
15. The adaptive evolution database (TAED)
16. Testing the covarion hypothesis of molcular evolution
17. Evolution of the Zfx and Zfy genes: Rates and interdependence between genes
18. Statistical methods for detecting adaptive evolution
19. A new method of inference of ancestral nucleotide and amino acid sequences
20. Estimating synonymous and nonsynonymous nucleotide substitution rates under realistic evolutionary models
21. Correlation between the substitution rate and rate variation among sites in protein evolution
22. Positive Darwinian selection after gene duplication in primate ribonuclease genes