The crystal structure of hypothetical methyltransferase from Thermus thermophilus HB8

Proteins: Structure, Function and Genetics

Volumn 64, Issue 2, 2006, Pages 552-558

  Sasaki, Chizuko ^a   Sugiura, Ikuko ^a   Ebihara, Akio ^b   Tamura, Takashi ^b,c   Sugio, Shigetoshi ^a   Inagaki, Kenji ^c  

^a ZOEGENE Corporation   (Japan)

^b RIKEN HARIMA INSTITUTE   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLTRANSFERASE;

ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; NONHUMAN; NOTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; THERMUS THERMOPHILUS;

THERMUS THERMOPHILUS;

EID: 33745613803     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21011     Document Type: Note

References (22)

1. Yokoyama S, Hirota H, Kigawa T, Yabuki T, Shirouzu M, Terada T, Ito Y, Matsuo Y, Kuroda Y, Kyogoku Y, Miki K, Masui R, Kuramitsu R. Structural genomics projects in Japan. Nat Struct Biol 2000;7(Suppl):943-945.
2. Pearson WR, Lipman DL. Improved tools for biological sequence comparison. Proc Natl Acad Sci USA 1988;85:2444-2448.
3. White O, Eisen JA, Fraser CM. Deinococcus radiodurans: genome sequence of the radioresistant bacterium Deinococcus radiodurans R1. Science 1999;286:1571-1577.
4. Kaiser O, Bartels D, Bekel T, Goesmann A, Kespohl S, Puhler A, Meyer F. Xanthomonas campestris: whole genome shotgun sequencing guided by bioinformatics pipelines - an optimized approach for an established technique. J Biotechnol 2003;106:121-133.
5. Larimer FW, Chain P, Harwood CS. Xanthomonas axonopodis: comparison of the genomes of two Xanthomonas pathogens with differing host specificities. Nat Biotechnol 2004;22:55-61.
6. Cheng X, Kumar S, Posfai J, Pflugrath JW and Roberts RJ. Crystal structure of the HhaI DNA methyltransferase complex with S-adenosyl-L- methionine. Cell 1993;74:299-307.
7. O'Gara M, NatHorton JR, Roberts RJ, Cheng X. Structure of HhaI DNA methyltransferase complex with substrates containing mismatches at the target base. Struct Biol 1998;5:872-877.
8. O'Gara M, Zhang X, Roberts RJ, Cheng X. Structure Of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide. J Mol Biol 1999;287:201-209.
9. Sheikhnejad G, Brank A, Christman JK, Goddard A, Alvarez E. Mechanism of inhibition of DNA (cytosine C5-methyltransferase by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine). J Mol Biol 1999;285:2021-2034.
10. Goedecke K, Pignot M, Goody RS, Scheidig AJ, Weinhold E. Structure of the N6-adenine DNA methyltransferase M. TaqI in complex with DNA and a cofactor. Nat Struct Biol 2001;8:121-125.
11. Labahn J, Granzin J, Schluckebier G, Robinson DP, Jack WE, Schildkraut I, Saenger W. Three-dimensional structure of the adenine-specific DNA methyltransferase M. TaqI in complex with the cofactor S-adenosylmethionine. Proc Natl Acad Sci USA 1994;91:10957-10961.
12. Schluckebier G, O'Gara M, Saenger W, Cheng X. Universal catalytic domain structure of AdoMet-dependent methyltransferases. J Mol Biol 1995;247:16-20.
13. Berman HM, Westbrook J, Feng Z, Gilland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE. The Protein Data Bank. Nucleic Acids Res 2000;28:235-242.
14. Martin JL, McMillan F. The S-adenosylmethionine-dependent methyltransferase fold. Curr Opin Struct Biol 2002;12:783-793.
15. Otwinowski Z, Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol 1997;276:307-326.
16. Terwilliger TC. Multi wavelength anomalous diffraction phasing of macromolecular structure: analysis of MAD data as single isomorphous replacement with anomalous scattering data using the MADMRG program. Methds Enzymol 1997;276:530.
17. Oldfield TJ, et al. A number of real space torsion angle refinement techniques for proteins, nucleic acids, ligands and solvents. Acta Crystallogr 2001;D57:82-94.
18. Brunge AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, Read RJ, Rice LM, Simonson T, Warren GL. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr 1998;D54:905-921.
19. Holm L, Sander C. Protein structure comparison by alignment of distance matrices, DALI. J Mol Biol 1993;233:123-138.
20. Hauang L, Hung L, Kim SH. Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii. J Struct Funct Genom 2002;2:121-127.
21. Vidgren J, Svensson LA, Lijas A. Crystal structure of catechol O-methyltransferase. Nature 1994;368:354-358.
22. Gong W, O'Gara M, Blumenthal RM, Cheng X. Structure of PvuII DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment. Nucleic Acids Res 1997;14:2702-2715.