Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice

Journal of Cellular Biochemistry

Volumn 98, Issue 4, 2006, Pages 966-980

  Xia, Zhidao ^a,c   Taylor, Philip R ^b   Locklin, Rachel M ^a   Gordon, Siamon ^b   Cui, Zhanfeng ^c   Triffitt, James T ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

CB17 scid beige mice; Green fluorescent protein (GFP); Human bone marrow fibroblastic (HBMF) cells; Innate immune response; Macrophages; Xenotransplantation

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE DEHYDROGENASE (NADP); GREEN FLUORESCENT PROTEIN; OSTEOCALCIN; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; BONE MARROW CELL; CELL POPULATION; FIBROBLAST; GENE THERAPY; GIANT CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMPLANTATION; INFLAMMATORY CELL; INNATE IMMUNITY; LYMPHOCYTE PROLIFERATION; MACROPHAGE ACTIVATION; MONOCYTE; MOUSE; MULTINUCLEAR CELL; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TISSUE ENGINEERING; XENOTRANSPLANTATION;

ANIMALS; BONE MARROW CELLS; CELL TRANSPLANTATION; DISEASE MODELS, ANIMAL; FIBROBLASTS; GRAFT REJECTION; HUMANS; IMMUNITY, NATURAL; MACROPHAGES; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NEUTROPHILS; TRANSPLANTATION, HETEROLOGOUS;

EID: 33745592774     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20730     Document Type: Article

References (50)

1. Aderem A, Ulevitch RJ. 2000. Toll-like receptors in the induction of the innate immune response. Nature 406:782-787.
2. Arase H, Saito T, Phillips JH, Lanier LL. 2001. Cutting edge: The mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). J Immunol 167:1141-1144.
3. Arinzeh TL, Peter SJ, Archambault MP, van den Bos C, Gordon S, Kraus K, Smith A, Kadiyala S. 2003. Allogeneic mesenchymal stem cells regenerate bone in a critical-sized canine segmental defect. J Bone Joint Surg Am 85(A):1927-1935.
4. Athanasou NA. 1996. Cellular biology of bone-resorbing cells. J Bone Joint Surg Am 78:1096-1112.
5. Bouchon A, Facchetti F, Weigand MA, Colonna M. 2001. TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 410:1103-1107.
6. Boyle WJ, Simonet WS, Lacey DL. 2003. Osteoclast differentiation and activation. Nature 423:337-342.
7. Boynton E, Aubin J, Gross A, Hozumi N, Sandhu J. 1996. Human osteoblasts survive and deposit new bone when human bone is implanted in SCID mouse. Bone 18:321-326.
8. Caplan AI. 1994. The mesengenic process. Clin Plast Surg 21:429-435.
9. Cilloni D, Carlo-Stella C, Falzetti F, Sammarelli G, Regazzi E, Colla S, Rizzoli V, Aversa F, Martelli MF, Tabilio A. 2000. Limited engraftment capacity of bone marrow-derived mesenchymal cells following T-cell-depleted hematopoietic stem cell transplantation. Blood 96:3637-3643.
10. Crocker PR, Kelm S, Dubois C, Martin B, McWilliam AS, Shotton DM, Paulson JC, Gordon S. 1991. Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages. EMBO J 10:1661-1669.
11. Domiati-Saad R, Ogle EW, Justement LB. 1993. Administration of anti-CD45 mAb specific for a B cell-restricted epitope abrogates the B cell response to a T-dependent antigen in vivo. J Immunol 151:5936-5947.
12. Ferrini S, Prigione I, Bottino C, Ciccone E, Tambussi G, Mammoliti S, Moretta L, Moretta A. 1989. Monoclonal antibodies which react with the T cell receptor gamma/ delta recognize different subsets of CD3 + WT31- T lymphocytes. Eur J Immunol 19:57-61.
13. Fox A, Harrison LC. 2000. Innate immunity and graft rejection. Immunol Rev 173:141-147.
14. Fox A, Mountford J, Braakhuis A, Harrison LC. 2001. Innate and adaptive immune responses to nonvascular xenografts: Evidence that macrophages are direct effectors of xenograft rejection. J Immunol 166:2133-2140.
15. Friedenstein AJ, Chailakhjan RK, Lalykina KS. 1970. The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet 3:393-403.
16. Froidevaux S, Loor F. 1991. A quick procedure for identifying doubly homozygous immunodeficient scid beige mice. J Immunol Methods 137:275-279.
17. Gotherstrom C, Ringden O, Westgren M, Tammik C, Le Blanc K. 2003. Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells. Bone Marrow Transplant 32:265-272.
18. Gronthos S, Zannettino AC, Hay SJ, Shi S, Graves SE, Kortesidis A, Simmons PJ. 2003. Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. J Cell Sci 116:1827-1835.
19. Gundle R, Joyner CJ, Triffitt JT. 1995. Human bone tissue formation in diffusion chamber culture in vivo by bone-derived cells and marrow stromal fibroblastic cells. Bone 16:597-601.
20. He H, Stone JR, Perkins DL. 2003. Analysis of differential immune responses induced by innate and adaptive immunity following transplantation. Immunology 109:185-196.
21. Hestdal K, Ruscetti FW, Ihle JN, Jacobsen SE, Dubois CM, Kopp WC, Longo DL, Keller JR. 1991. Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells. J Immunol 147:22-28.
22. Hoffmann JA, Kafatos FC, Janeway CA, Ezekowitz RA. 1999. Phylogenetic perspectives in innate immunity. Science 284:1313-1318.
23. Hume DA, Loutit JF, Gordon S. 1984. The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: Macrophages of bone and associated connective tissue. J Cell Sci 66:189-194.
24. Kimbrell DA, Beutler B. 2001. The evolution and genetics of innate immunity. Nat Rev Genet 2:256-267.
25. Koc ON, Peters C, Aubourg P, Raghavan S, Dyhouse S, DeGasperi R, Kolodny EH, Yoseph YB, Gerson SL, Lazarus HM, Caplan AI, Watkins PA, Krivit W. 1999. Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases. Exp Hematol 27:1675-1681.
26. Le Blanc K, Rasmusson I, Sundberg B, Gotherstrom C, Hassan M, Uzunel M, Ringden O. 2004. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 363:1439-1441.
27. Lee K, Majumdar MK, Buyaner D, Hendricks JK, Pittenger MF, Mosca JD. 2001. Human mesenchymal stem cells maintain transgene expression during expansion and differentiation. Mol Ther 3:857-866.
28. Lee JJ, Nam CE, Kook H, Maciejewski JP, Kim YK, Chung IJ, Park KS, Lee IK, Hwang TJ, Kim HJ. 2003. Constitution and telomere dynamics of bone marrow stromal cells in patients undergoing allogeneic bone marrow transplantation. Bone Marrow Transplant 32:947-952.
29. Liechty KW, MacKenzie TC, Shaaban AF, Radu A, Moseley AM, Deans R, Marshak DR, Flake AW. 2000. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med 6:1282-1286.
30. Linehan SA, Martinez-Pomares L, Stahl PD, Gordon S. 1999. Mannose receptor and its putative ligands in normal murine lymphoid and nonlymphoid organs: In situ expression of mannose receptor by selected macrophages, endothelial cells, perivascular microglia, and mesangial cells, but not dendritic cells. J Exp Med 189:1961-1972.
31. Martinez-Pomares L, Reid DM, Brown GD, Taylor PR, Stillion RJ, Linehan SA, Zamze S, Gordon S, Wong SY. 2003. Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies. J Leukoc Biol 73:604-613.
32. Matsumoto S, Shibuya I, Kusakari S, Segawa K, Uyama T, Shimada A, Umezawa A. 2005. Membranous osteogenesis system modeled with KUSA-A1 mature osteoblasts. Biochim Biophys Acta 1725:57-63.
33. Niyibizi C, Wang S, Mi Z, Robbins PD. 2004. The fate of mesenchymal stem cells transplanted into immunocompetent neonatal mice: Implications for skeletal gene therapy via stem cells. Mol Ther 9:955-963.
34. Oreffo RO, Kusec V, Romberg S, Triffitt JT. 1999. Human bone marrow osteoprogenitors express estrogen receptor-alpha and bone morphogenetic proteins 2 and 4 mRNA during osteoblastic differentiation. J Cell Biochem 75:382-392.
35. Owen M. 1988. Marrow stromal stem cells. J Cell Sci Suppl 10:63-76.
36. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR. 1999. Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147.
37. Platt JL. 1999. Prospects for xenotransplantation. Pediatr Transplant 3:193-200.
38. Rabinowitz SS, Gordon S. 1991. Macrosialin, a macrophage-restricted membrane sialoprotein differentially glycosylated in response to inflammatory stimuli. J Exp Med 174:827-836.
39. Rosen H, Gordon S. 1987. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo. J Exp Med 166:1685-1701.
40. Schuler W, Weiler IJ, Schuler A, Phillips RA, Rosenberg N, Mak TW, Kearney JF, Perry RP, Bosma MJ. 1986. Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency. Cell 46:963-972.
41. Shortman K, Liu YJ. 2002. Mouse and human dendritic cell subtypes. Nat Rev Immunol 2:151-161.
42. Taylor PR, Brown GD, Reid DM, Willment JA, Martinez-Pomares L, Gordon S, Wong SY. 2002. The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. J Immunol 169:3876-3882.
43. Taylor PR, Brown GD, Geldhof AB, Martinez-Pomares L, Gordon S. 2003. Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo. Eur J Immunol 33:2090-2097.
44. Teitelbaum SL. 2000. Bone resorption by osteoclasts. Science 289:1504-1508.
45. Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD. 2002. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105:93-98.
46. Triffitt JT, Oreffo RO, Virdi AS, Xia Z. 2001. Osteogenic stem-cell characterization and development: Potentials for cytotherapy. Cytotherapy 3:413-416.
47. Tsuda H, Wada T, Ito Y, Uchida H, Dehari H, Nakamura K, Sasaki K, Kobune M, Yamashita T, Hamada H. 2003. Efficient BMP2 gene transfer and bone formation of mesenchymal stem cells by a fiber-mutant adenoviral vector. Mol Ther 7:354-365.
48. Xia Z, Ye H, Choong C, Ferguson DJ, Platt N, Cui Z, Triffitt JT. 2004. Macrophagic response to human mesenchymal stem cell and poly(epsilon- caprolactone) implantation in nonobese diabetic/severe combined immunodeficient mice. J Biomed Mater Res 71A:538-548.
49. Xia Z, Ye H, Locklin RM, Ferguson DJ, Cui Z, Triffitt JT. 2005. Efficient characterisation of human cell-bioceramic interactions in vitro and in vivo by using enhanced GFP-labelled mesenchymal stem cells. Biomaterials 26:5790-5800.
50. Yamamoto T, Ecarot B, Glorieux FH. 1991. In vivo osteogenic activity of isolated human bone cells. J Bone Miner Res 6:45-51.