Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis

International Journal of Pharmaceutics

Volumn 229, Issue 1-2, 2001, Pages 75-86

  Johnston, Thomas P ^a   Nguyen, Lien B ^b   Chu, Waihei A ^a   Shefer, Sarah ^b  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

3 hydroxy 3 methylglutaryl coenzyme A reductase; 7 hydroxylase; Atherosclerosis; Bile acids; Hypercholesterolemia; Statin drugs; Sterol 27 hydroxylase

Indexed keywords

ATORVASTATIN; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN; MEVINOLIN; POLOXAMER; PRAVASTATIN; SIMVASTATIN; STEROL 27 HYDROXYLASE; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATHEROMA; ATHEROSCLEROSIS; CATABOLISM; CATALYSIS; CELL LINE; CHOLESTEROL SYNTHESIS; COMPARATIVE STUDY; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SOLUBILITY; ENZYME ACTIVITY; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUPPLEMENTATION; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTICHOLESTEREMIC AGENTS; ARTERIOSCLEROSIS; CHOLESTEROL; FEMALE; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERLIPIDEMIAS; LIVER; MICE; MICE, INBRED C57BL; TRIGLYCERIDES;

EID: 0035965514     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00834-1     Document Type: Article

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