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Volumn 26, Issue 7 II, 2006, Pages

Statin-associated pleiotropy: Possible beneficial effects beyond cholesterol reduction

Author keywords

3 hydroxy 3 methylglutaryl coenzyme A reductase inhibitors; Dyslipidemia; HMG CoA; Pleiotropy cardiovascular risk; Statins

Indexed keywords

CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

EID: 33745590135     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.26.7part2.85S     Document Type: Conference Paper
Times cited : (46)

References (64)
  • 1
    • 3142729178 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelines
    • Grundy SM, Cleeman JI, Merz CN, et al. Implications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelines. Circulation 2004;110:227-39.
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.3
  • 2
    • 4043135767 scopus 로고    scopus 로고
    • Erratum
    • (Erratum in Circulation 2004;110:763.)
    • (2004) Circulation , vol.110 , pp. 763
  • 3
    • 23744475368 scopus 로고    scopus 로고
    • Pharmacologic options for aggressive low-density lipoprotein cholesterol lowering benefits versus risks
    • McKenney JM. Pharmacologic options for aggressive low-density lipoprotein cholesterol lowering benefits versus risks. Am J Cardiol 2005;96:E60-6.
    • (2005) Am J Cardiol , vol.96
    • McKenney, J.M.1
  • 4
    • 0033985565 scopus 로고    scopus 로고
    • Management of hypercholesterolemia
    • Illingworth DR. Management of hypercholesterolemia. Med Clin North Am 2000;84:23-42.
    • (2000) Med Clin North Am , vol.84 , pp. 23-42
    • Illingworth, D.R.1
  • 5
    • 0038645309 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* trial)
    • Jones PH, Davidson MH, Stein EA, et al. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* trial). Am J Cardiol 2003;92:152-60.
    • (2003) Am J Cardiol , vol.92 , pp. 152-160
    • Jones, P.H.1    Davidson, M.H.2    Stein, E.A.3
  • 6
    • 0042231088 scopus 로고    scopus 로고
    • Statins, inflammation, and sepsis: Hypothesis
    • Almog Y. Statins, inflammation, and sepsis: hypothesis. Chest 2003;124:740-3.
    • (2003) Chest , vol.124 , pp. 740-743
    • Almog, Y.1
  • 7
    • 4143083577 scopus 로고    scopus 로고
    • Prior statin therapy is associated with a decreased rate of severe sepsis
    • Almog Y, Shefer A, Novack V, et al. Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 2004;110:880-5.
    • (2004) Circulation , vol.110 , pp. 880-885
    • Almog, Y.1    Shefer, A.2    Novack, V.3
  • 9
    • 20844457621 scopus 로고    scopus 로고
    • The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease
    • Hoglund K, Thelen KM, Syversen S, et al. The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease. Dement Geriatr Cogn Disord 2005;19:256-65.
    • (2005) Dement Geriatr Cogn Disord , vol.19 , pp. 256-265
    • Hoglund, K.1    Thelen, K.M.2    Syversen, S.3
  • 10
    • 21844463540 scopus 로고    scopus 로고
    • Statin treatment after onset of sepsis in a murine model improves survival
    • Merx MW, Liehn EA, Graf J, et al. Statin treatment after onset of sepsis in a murine model improves survival. Circulation 2005;112:117-24.
    • (2005) Circulation , vol.112 , pp. 117-124
    • Merx, M.W.1    Liehn, E.A.2    Graf, J.3
  • 11
    • 20844440894 scopus 로고    scopus 로고
    • Atorvastatin for the treatment of mild to moderate Alzheimer disease: Preliminary results
    • Sparks DL, Sabbagh MN, Connor DJ, et al. Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results. Arch Neurol 2005;62:753-7.
    • (2005) Arch Neurol , vol.62 , pp. 753-757
    • Sparks, D.L.1    Sabbagh, M.N.2    Connor, D.J.3
  • 14
    • 17144407602 scopus 로고    scopus 로고
    • Should treatment of sepsis include statins?
    • Warnholtz A, Genth-Zotz S, Munzel T. Should treatment of sepsis include statins? Circulation 2005;111:1735-7.
    • (2005) Circulation , vol.111 , pp. 1735-1737
    • Warnholtz, A.1    Genth-Zotz, S.2    Munzel, T.3
  • 15
    • 20244378532 scopus 로고    scopus 로고
    • Simvastatin blunts endotoxin-induced tissue factor in vivo
    • Steiner S, Speidl WS, Pleiner J, et al. Simvastatin blunts endotoxin-induced tissue factor in vivo. Circulation 2005; 111:1841-6.
    • (2005) Circulation , vol.111 , pp. 1841-1846
    • Steiner, S.1    Speidl, W.S.2    Pleiner, J.3
  • 16
    • 0035804846 scopus 로고    scopus 로고
    • Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: The MIRACL study - A randomized controlled trial
    • Schwartz GG, Olsson AG, Ezekowitz MD, et al. Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: the MIRACL study - a randomized controlled trial. JAMA 2001;285:1711-18.
    • (2001) JAMA , vol.285 , pp. 1711-1718
    • Schwartz, G.G.1    Olsson, A.G.2    Ezekowitz, M.D.3
  • 17
    • 11344279659 scopus 로고    scopus 로고
    • C-reactive protein levels and outcomes after statin therapy
    • Ridker PM, Cannon CP, Morrow D, et al. C-reactive protein levels and outcomes after statin therapy. N Engl J Med 2005;352:20-8.
    • (2005) N Engl J Med , vol.352 , pp. 20-28
    • Ridker, P.M.1    Cannon, C.P.2    Morrow, D.3
  • 18
    • 1242295184 scopus 로고    scopus 로고
    • Statin therapy is associated with improved survival in ischemic and non-ischemic heart failure
    • Horwich TB, MacLellan WR, Fonarow GC. Statin therapy is associated with improved survival in ischemic and non-ischemic heart failure. J Am Coll Cardiol 2004;43:642-8.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 642-648
    • Horwich, T.B.1    MacLellan, W.R.2    Fonarow, G.C.3
  • 19
    • 22544443085 scopus 로고    scopus 로고
    • Statin therapy may be associated with lower mortality in patients with diastolic heart failure: A preliminary report
    • Fukuta H, Sane DC, Brucks S, Little WC. Statin therapy may be associated with lower mortality in patients with diastolic heart failure: a preliminary report. Circulation 2005;112:357-63.
    • (2005) Circulation , vol.112 , pp. 357-363
    • Fukuta, H.1    Sane, D.C.2    Brucks, S.3    Little, W.C.4
  • 20
    • 1942500310 scopus 로고    scopus 로고
    • Statin therapy is associated with lower mortality among patients with severe heart failure
    • Mozaffarian D, Nye R, Levy WC. Statin therapy is associated with lower mortality among patients with severe heart failure. Am J Cardiol 2004;93:1124-9.
    • (2004) Am J Cardiol , vol.93 , pp. 1124-1129
    • Mozaffarian, D.1    Nye, R.2    Levy, W.C.3
  • 21
    • 11844304039 scopus 로고    scopus 로고
    • Statin use and survival outcomes in elderly patients with heart failure
    • Ray JG, Gong Y, Sykora K, Tu JV. Statin use and survival outcomes in elderly patients with heart failure. Arch Intern Med 2005;165:62-7.
    • (2005) Arch Intern Med , vol.165 , pp. 62-67
    • Ray, J.G.1    Gong, Y.2    Sykora, K.3    Tu, J.V.4
  • 22
    • 0029155841 scopus 로고
    • Disease-free intervals after partial ileal bypass in patients with coronary heart disease and hypercholesterolemia: Report from the program on the surgical control of the hyperlipidemias (POSCH)
    • Buchwald H, Campos CT, Boen JR, Nguyen PA, Williams SE. Disease-free intervals after partial ileal bypass in patients with coronary heart disease and hypercholesterolemia: report from the program on the surgical control of the hyperlipidemias (POSCH). J Am Coll Cardiol 1995;26:351-7.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 351-357
    • Buchwald, H.1    Campos, C.T.2    Boen, J.R.3    Nguyen, P.A.4    Williams, S.E.5
  • 23
    • 0025086998 scopus 로고
    • Effect of partial ileal bypass surgery on mortality and morbidity from coronary heart disease in patients with hypercholesterolemia: Report of the program on the surgical control of the hyperlipidemias (POSCH)
    • Buchwald H, Varco RL, Matts JP, et al. Effect of partial ileal bypass surgery on mortality and morbidity from coronary heart disease in patients with hypercholesterolemia: report of the program on the surgical control of the hyperlipidemias (POSCH). N Engl J Med 1990;323:946-55.
    • (1990) N Engl J Med , vol.323 , pp. 946-955
    • Buchwald, H.1    Varco, R.L.2    Matts, J.P.3
  • 24
    • 0021270282 scopus 로고
    • Lipid research clinics coronary primary prevention trial: Results and implications
    • Rifkind BM. Lipid research clinics coronary primary prevention trial: results and implications. Am J Cardiol 1984;54:C30-4.
    • (1984) Am J Cardiol , vol.54
    • Rifkind, B.M.1
  • 25
    • 0021349709 scopus 로고
    • Lipid research clinics coronary primary prevention trial results. II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering
    • The LRC-CPPT Group. Lipid research clinics coronary primary prevention trial results. II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA 1984;251:365-74.
    • (1984) JAMA , vol.251 , pp. 365-374
  • 26
    • 0026090478 scopus 로고
    • The lipid research clinics coronary primary prevention trial: Design, results, and implications
    • Probstfield JL, Rifkind BM. The lipid research clinics coronary primary prevention trial: design, results, and implications. Eur J Clin Pharmacol 1991;40(suppl 1):S69-75.
    • (1991) Eur J Clin Pharmacol , vol.40 , Issue.SUPPL. 1
    • Probstfield, J.L.1    Rifkind, B.M.2
  • 28
    • 0032554676 scopus 로고    scopus 로고
    • Influence of pravastatin and plasma lipids on clinical events in the West of Scotland coronary prevention study (WOSCOPS)
    • West of Scotland Coronary Prevention Study Group. Influence of pravastatin and plasma lipids on clinical events in the West of Scotland coronary prevention study (WOSCOPS). Circulation 1998;97:1440-5.
    • (1998) Circulation , vol.97 , pp. 1440-1445
  • 29
    • 0035936527 scopus 로고    scopus 로고
    • Pravastatin and the development of diabetes mellitus: Evidence for a protective treatment effect in the West of Scotland coronary prevention study
    • Freeman DJ, Norrie J, Sattar N, et al. Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the West of Scotland coronary prevention study. Circulation 2001;103:357-62.
    • (2001) Circulation , vol.103 , pp. 357-362
    • Freeman, D.J.1    Norrie, J.2    Sattar, N.3
  • 30
    • 0034604225 scopus 로고    scopus 로고
    • Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: The bezafibrate infarction prevention (BIP) study
    • The BIP Study Group. Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: the bezafibrate infarction prevention (BIP) study. Circulation 2000;102:21-7.
    • (2000) Circulation , vol.102 , pp. 21-27
  • 31
    • 26444604923 scopus 로고    scopus 로고
    • Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients
    • Tenenbaum A, Motro M, Fisman EZ, et al. Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients. Eur Heart J 2005;26:2032-8.
    • (2005) Eur Heart J , vol.26 , pp. 2032-2038
    • Tenenbaum, A.1    Motro, M.2    Fisman, E.Z.3
  • 32
    • 23944497531 scopus 로고    scopus 로고
    • Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortality
    • Fonarow GC, Wright RS, Spencer FA, et al. Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortality. Am J Cardiol 2005;96:611-16.
    • (2005) Am J Cardiol , vol.96 , pp. 611-616
    • Fonarow, G.C.1    Wright, R.S.2    Spencer, F.A.3
  • 33
    • 10744225301 scopus 로고    scopus 로고
    • Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trial
    • Nissen SE, Tuzcu EM, Schoenhagen P, et al. Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. JAMA 2004;291:1071-80.
    • (2004) JAMA , vol.291 , pp. 1071-1080
    • Nissen, S.E.1    Tuzcu, E.M.2    Schoenhagen, P.3
  • 34
    • 11144355354 scopus 로고    scopus 로고
    • Intensive versus moderate lipid lowering with statins after acute coronary syndromes
    • Cannon CP, Braunwald E, McCabe CH, et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 2004;350:1495-504.
    • (2004) N Engl J Med , vol.350 , pp. 1495-1504
    • Cannon, C.P.1    Braunwald, E.2    McCabe, C.H.3
  • 35
    • 0141841612 scopus 로고    scopus 로고
    • High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study
    • Kinlay S, Schwartz GG, Olsson AG, et al. High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study. Circulation 2003;108:1560-6.
    • (2003) Circulation , vol.108 , pp. 1560-1566
    • Kinlay, S.1    Schwartz, G.G.2    Olsson, A.G.3
  • 36
    • 19944429519 scopus 로고    scopus 로고
    • Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease
    • Nissen SE, Tuzcu EM, Schoenhagen P, et al. Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. N Engl J Med 2005;352:29-38.
    • (2005) N Engl J Med , vol.352 , pp. 29-38
    • Nissen, S.E.1    Tuzcu, E.M.2    Schoenhagen, P.3
  • 37
    • 26844522123 scopus 로고    scopus 로고
    • Relationship between uncontrolled risk factors and C-reactive protein levels in patients receiving standard or intensive statin therapy for acute coronary syndromes in the PROVE IT-TIMI 22 trial
    • Ray KK, Cannon CP, Cairns R, et al. Relationship between uncontrolled risk factors and C-reactive protein levels in patients receiving standard or intensive statin therapy for acute coronary syndromes in the PROVE IT-TIMI 22 trial. J Am Coll Cardiol 2005;46:1417-24.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1417-1424
    • Ray, K.K.1    Cannon, C.P.2    Cairns, R.3
  • 38
    • 26844468578 scopus 로고    scopus 로고
    • Can low-density lipoprotein be too low? the safety and efficacy of achieving very low low-density lipoprotein with intensive statin therapy: A PROVE IT-TIMI 22 substudy
    • Wiviott SD, Cannon CP, Morrow DA, Ray KK, Pfeffer MA, Braunwald E. Can low-density lipoprotein be too low? The safety and efficacy of achieving very low low-density lipoprotein with intensive statin therapy: a PROVE IT-TIMI 22 substudy. J Am Coll Cardiol 2005;46:1411-6.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1411-1416
    • Wiviott, S.D.1    Cannon, C.P.2    Morrow, D.A.3    Ray, K.K.4    Pfeffer, M.A.5    Braunwald, E.6
  • 39
    • 33745591067 scopus 로고    scopus 로고
    • Pravachol (pravastatin sodium)
    • Montvale, NJ: Thomson PDR
    • Anonymous. Pravachol (pravastatin sodium). In: Physicians' desk reference, 60th ed. Montvale, NJ: Thomson PDR, 2006:943-8.
    • (2006) Physicians' Desk Reference, 60th Ed. , pp. 943-948
  • 40
    • 33745620693 scopus 로고    scopus 로고
    • Lipitor (atorvastatin calcium)
    • Montvale, NJ: Thomson PDR
    • Anonymous. Lipitor (atorvastatin calcium). In: Physicians' desk reference, 60th ed. Montvale, NJ: Thomson PDR, 2006:2495-8.
    • (2006) Physicians' Desk Reference, 60th Ed. , pp. 2495-2498
  • 41
    • 23944446113 scopus 로고    scopus 로고
    • Early time to benefit with intensive statin treatment: Could it be the pleiotropic effects?
    • Ray KK, Cannon CP. Early time to benefit with intensive statin treatment: could it be the pleiotropic effects? Am J Cardiol 2005;96:F54-60.
    • (2005) Am J Cardiol , vol.96
    • Ray, K.K.1    Cannon, C.P.2
  • 42
    • 0141885294 scopus 로고    scopus 로고
    • From vulnerable plaque to vulnerable patient: A call for new definitions and risk assessment strategies-part 1
    • Naghavi M, Libby P, Falk E, et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies-part 1. Circulation 2003;108:1664-72.
    • (2003) Circulation , vol.108 , pp. 1664-1672
    • Naghavi, M.1    Libby, P.2    Falk, E.3
  • 43
    • 0142053972 scopus 로고    scopus 로고
    • From vulnerable plaque to vulnerable patient: A call for new definitions and risk assessment strategies-part II
    • Naghavi M, Libby P, Falk E, et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies-part II. Circulation 2003;108:1772-8.
    • (2003) Circulation , vol.108 , pp. 1772-1778
    • Naghavi, M.1    Libby, P.2    Falk, E.3
  • 44
    • 15944410609 scopus 로고    scopus 로고
    • Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 2005;352:1425-35.
    • (2005) N Engl J Med , vol.352 , pp. 1425-1435
    • LaRosa, J.C.1    Grundy, S.M.2    Waters, D.D.3
  • 45
    • 0034252616 scopus 로고    scopus 로고
    • A pilot study with simvastatin and folic acid/vitamin B12 in preparation for the study of the effectiveness of additional reductions in cholesterol and homocysteine (SEARCH)
    • MacMahon M, Kirkpatrick C, Cummings CE, et al. A pilot study with simvastatin and folic acid/vitamin B12 in preparation for the study of the effectiveness of additional reductions in cholesterol and homocysteine (SEARCH). Nutr Metab Cardiovasc Dis 2000;10:195-203.
    • (2000) Nutr Metab Cardiovasc Dis , vol.10 , pp. 195-203
    • MacMahon, M.1    Kirkpatrick, C.2    Cummings, C.E.3
  • 47
    • 22544463145 scopus 로고    scopus 로고
    • Treating diastolic heart failure with statins: "phat" chance for pleiotropic benefits
    • Zile MR. Treating diastolic heart failure with statins: "phat" chance for pleiotropic benefits. Circulation 2005;112:300-3.
    • (2005) Circulation , vol.112 , pp. 300-303
    • Zile, M.R.1
  • 48
    • 0037133660 scopus 로고    scopus 로고
    • New concepts in diastolic dysfunction and diastolic heart failure. 1. Diagnosis, prognosis, and measurements of diastolic function
    • Zile MR, Brutsaert DL. New concepts in diastolic dysfunction and diastolic heart failure. 1. Diagnosis, prognosis, and measurements of diastolic function. Circulation 2002;105: 1387-93.
    • (2002) Circulation , vol.105 , pp. 1387-1393
    • Zile, M.R.1    Brutsaert, D.L.2
  • 49
    • 18244362843 scopus 로고    scopus 로고
    • Rosuvastatin reduces platelet activation in heart failure: Role of NO bioavailability
    • Schafer A, Fraccarollo D, Eigenthaler M, et al. Rosuvastatin reduces platelet activation in heart failure: role of NO bioavailability. Arterioscler Thromb Vasc Biol 2005;25:1071-7.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1071-1077
    • Schafer, A.1    Fraccarollo, D.2    Eigenthaler, M.3
  • 50
    • 21844474541 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy
    • Ii M, Nishimura H, Kusano KF, et al. Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy. Circulation 2005; 112:93-102.
    • (2005) Circulation , vol.112 , pp. 93-102
    • Ii, M.1    Nishimura, H.2    Kusano, K.F.3
  • 51
    • 26644434838 scopus 로고    scopus 로고
    • A statin in the treatment of heart failure? Controlled rosuvastatin multinational study in heart failure (CORONA): Study design and baseline characteristics
    • Kjekshus J, Dunselman P, Blideskog M, et al. A statin in the treatment of heart failure? Controlled rosuvastatin multinational study in heart failure (CORONA): study design and baseline characteristics. Eur J Heart Fail 2005;7:1059-69.
    • (2005) Eur J Heart Fail , vol.7 , pp. 1059-1069
    • Kjekshus, J.1    Dunselman, P.2    Blideskog, M.3
  • 52
    • 0035902456 scopus 로고    scopus 로고
    • Current concepts of the pathogenesis of the acute coronary syndromes
    • Libby P. Current concepts of the pathogenesis of the acute coronary syndromes. Circulation 2001;104:365-72.
    • (2001) Circulation , vol.104 , pp. 365-372
    • Libby, P.1
  • 53
    • 21544467275 scopus 로고    scopus 로고
    • Pathophysiology of coronary artery disease
    • Libby P, Theroux P. Pathophysiology of coronary artery disease. Circulation 2005;111:3481-8.
    • (2005) Circulation , vol.111 , pp. 3481-3488
    • Libby, P.1    Theroux, P.2
  • 54
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M, Liao JK. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Arterioscler Thromb Vasc Biol 2001;21:1712-19.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 55
    • 0023028215 scopus 로고
    • Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries
    • Ludmer PL, Selwyn AP, Shook TL, et al. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N Engl J Med 1986;315:1046-51.
    • (1986) N Engl J Med , vol.315 , pp. 1046-1051
    • Ludmer, P.L.1    Selwyn, A.P.2    Shook, T.L.3
  • 56
    • 0034115408 scopus 로고    scopus 로고
    • The effect of cholesterol lowering on carotid and femoral artery wall stiffness and thickness in patients with familial hypercholesterolaemia
    • Smilde TJ, van den Berkmortel FW, Wollersheim H, van Langen H, Kastelein JJ, Stalenhoef AF. The effect of cholesterol lowering on carotid and femoral artery wall stiffness and thickness in patients with familial hypercholesterolaemia. Eur J Clin Invest 2000;30:473-80.
    • (2000) Eur J Clin Invest , vol.30 , pp. 473-480
    • Smilde, T.J.1    Van Den Berkmortel, F.W.2    Wollersheim, H.3    Van Langen, H.4    Kastelein, J.J.5    Stalenhoef, A.F.6
  • 57
    • 0037139284 scopus 로고    scopus 로고
    • Intensive cholesterol reduction lowers blood pressure and large artery stiffness in isolated systolic hypertension
    • Ferrier KE, Muhlmann MH, Baguet JP, et al. Intensive cholesterol reduction lowers blood pressure and large artery stiffness in isolated systolic hypertension. J Am Coll Cardiol 2002;39:1020-5.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1020-1025
    • Ferrier, K.E.1    Muhlmann, M.H.2    Baguet, J.P.3
  • 58
    • 0033454062 scopus 로고    scopus 로고
    • Effect of the HMG-CoA reductase inhibitors on blood pressure in patients with essential hypertension and primary hypercholesterolemia
    • Glorioso N, Troffa C, Filigheddu F, et al. Effect of the HMG-CoA reductase inhibitors on blood pressure in patients with essential hypertension and primary hypercholesterolemia. Hypertension 1999;34:1281-6.
    • (1999) Hypertension , vol.34 , pp. 1281-1286
    • Glorioso, N.1    Troffa, C.2    Filigheddu, F.3
  • 59
    • 1042268126 scopus 로고    scopus 로고
    • Statins induce the regression of left ventricular mass in patients with angina
    • Nishikawa H, Miura S, Zhang B, et al. Statins induce the regression of left ventricular mass in patients with angina. Circ J 2004;68:121-5.
    • (2004) Circ J , vol.68 , pp. 121-125
    • Nishikawa, H.1    Miura, S.2    Zhang, B.3
  • 60
    • 0035902491 scopus 로고    scopus 로고
    • Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy
    • Patel R, Nagueh SF, Tsybouleva N, et al. Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circulation 2001;104:317-24.
    • (2001) Circulation , vol.104 , pp. 317-324
    • Patel, R.1    Nagueh, S.F.2    Tsybouleva, N.3
  • 61
    • 0037109099 scopus 로고    scopus 로고
    • Hydroxymethylglutaryl coenzyme a reductase inhibitor simvastatin prevents cardiac hypertrophy induced by pressure overload and inhibits p21ras activation
    • Indolfi C, Di Lorenzo E, Perrino C, et al. Hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin prevents cardiac hypertrophy induced by pressure overload and inhibits p21ras activation. Circulation 2002;106:2118-24.
    • (2002) Circulation , vol.106 , pp. 2118-2124
    • Indolfi, C.1    Di Lorenzo, E.2    Perrino, C.3
  • 62
    • 0035964390 scopus 로고    scopus 로고
    • Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme a reductase inhibition with cerivastatin in rats with heart failure after myocardial infarction
    • Bauersachs J, Galuppo P, Fraccarollo D, Christ M, Ertl G. Improvement of left ventricular remodeling and function by hydroxymethylglutaryl coenzyme A reductase inhibition with cerivastatin in rats with heart failure after myocardial infarction. Circulation 2001;104:982-5.
    • (2001) Circulation , vol.104 , pp. 982-985
    • Bauersachs, J.1    Galuppo, P.2    Fraccarollo, D.3    Christ, M.4    Ertl, G.5
  • 63
    • 0037133338 scopus 로고    scopus 로고
    • Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction
    • Hayashidani S, Tsutsui H, Shiomi T, et al. Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction. Circulation 2002;105: 868-73.
    • (2002) Circulation , vol.105 , pp. 868-873
    • Hayashidani, S.1    Tsutsui, H.2    Shiomi, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.