Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung

Inhalation Toxicology

Volumn 18, Issue 8, 2006, Pages 581-588

  Qin, Guohua ^a   Meng, Ziqiang ^a  

^a SHANXI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; COMPLEMENTARY DNA; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2E1; MESSENGER RNA; OXYGENASE; PENTOXYRESORUFIN DEALKYLASE; SULFUR DIOXIDE;

AIR POLLUTANT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DNA SYNTHESIS; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; INHALATION; LIVER MICROSOME; LIVER WEIGHT; LUNG; LUNG WEIGHT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; XENOBIOTIC METABOLISM;

ADMINISTRATION, INHALATION; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP2E1; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; LIVER; LUNG; MALE; RATS; RATS, WISTAR; RNA, MESSENGER; STEROID HYDROXYLASES; SULFUR DIOXIDE;

RATTUS NORVEGICUS;

EID: 33745551280     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.1080/08958370600686341     Document Type: Article

References (61)

1. Abdel-Razzak, Z., Loyer, P., Fautrel, A., Gautier, J., Corcos, L., Turlin, B., Beaune, P., and Guillouzo, A. 1993. Cytokines down-regulate expression of major cytochrome P450 enzymes in adult human hepatocytes in primary culture. Mol. Pharmacol. 44:707-715.
2. Archakov, A. I., and Khukov, A. A. 1987. A multiplicity of cytochrome P450 activities: Stoichiometerical aqpproach. In Drug metabolism - From molecules to man; eds. D. J. Benford, J. W. Bridges, and G. G. Gibson, pp. 473-476. London: Taylor & Francis.
3. Aubrecht, J., Hirsch-Ernst, K. I., Becker-Rabbenstein, V., Kahl, G. F., Taniguchi, H., and Höhne, M. W. 1995. Induction of cytochrome P-4502B1-related mouse cytochrome P-450 and regulation of its expression by epidermal growth factor/transforming growth factor α in primary hepatocyte cultures. Biochem. Pharmacol. 50:781-785.
4. Bae, Y. S., Kang, S. W., Seo, M. S., Baines, I. C., Tekle, E., Chock, P. B., and Rhee, S. G. 1997. Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. J. Biol. Chem. 272:217-221
5. Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
6. Burke, M. D., Thompson, S., Elcombe, C. R., Halpert, J., Haaparanta, T., and Mayer, R. T. 1985. Ethoxy-, pentoxy-and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P450. Biochem. Pharmacol. 34:3337-3345.
7. Carlson, T. J., and Billings, R. E. 1996. Role of nitric oxide in the cytokine-mediated regulation of cytochrome P-450. Mol. Pharmacol. 49:796-801.
8. Chang, T. K., Weber, G. F., Crespi, C. L., and Waxman, D. J. 1993. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res. 53:5629-5637.
9. Chawla, A., Saez, E., and Evans, R. M., 2000. Don't know much bileology. Cell 103:1-4.
10. Chawla, A., Repa, J. J., Evans, R. M., and Mangelsdorf, D. J. 2001. Nuclear receptors and lipid physiology: Opening the X-files. Science 294:1866-1870.
11. Cho, M. K., Kim, Y. G., Lee, M. G., and Kim, S. G. 1999. Suppression of rat hepatic cytochrome P450s by protein-calorie malnutrition: Complete or partial restoration by cysteine or methionine supplementation. Arch. Biochem. Biophys. 372:150-158.
12. Clark, M. A., Bing, B. A., Gottschall, P. E., and Williams, J. F. 1995. Differential effect of cytokines on the phenobarbital or 3-methylcholanthrene induction of P450 mediated monooxygenase activity in cultured rat hepatocytes. Biochem. Pharmacol. 49:97-104.
13. Code, E. L., Crespi, C. L., Penman, B. W., Gonzalez, F. J., Chang, T. K., and Waxman, D. J. 1997. Human cytochrome P4502B6: Interindividual hepatic expression, substrate specificity, and role in procarcinogen activation. Drug Metab. Dispos. 25:985-993.
14. Dehal, S. S., and Kupfer, D. 1994. Metabolism of the proestrogenic pesticide methoxychlorby hepatic P450 monooxygenases in rats and humans. Dual pathways involving novel ortho ring-hydroxylation by CYP2B. Drug Metab. Dispos. 22:937-946.
15. de Waziers, I., Cugnenc, P. H., Yang, C. S., Leroux, J. P., and Beaune, P. H. 1990. Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. J. Pharmacol. Exp. Ther. 253:387-394.
16. Ferris, B. G., Jr, Burgess, W. A., and Worcester, J. 1967. Prevalence of chronic respiratory disease in a pulp mill and a paper mill in the United States. Br. J. Ind. Med, 24:26-37.
17. Fouchecourt, M. O., and Riviere, J. L. 1995. Activities of cytochrome P450-dependent monooxygenases and antioxidant enzymes in different organs of Norway rats (Rattus norvegicus) inhabiting reference and contaminated sites. Chemosphere 31:4375-4386.
18. Ghezzi, P., Saccardo, B., Villa, P., Rossi, V., Bianchi, M., and Dinarello, C. A. 1976. Role of interleukin-1 in the depression of liver drug metabolism by endotoxin. Infect. Immun. 54:351-353.
19. Gonzalez, F. J. 1992. Human cytochrome P450:problems and prospects. Trends Pharmacol. Sci. 13:346-352.
20. 2 determination and method sensitivity analysis. J. Environ. Monit. 3:666-670.
21. Guengerich, F. P. 1993. Cytochrome P450 enzymes. Am. Sci. 81:440-442.
22. Guengerich, F. P., Kim, D. -H., and Iwasaki, M. 1991. Role of human cytochrome P450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol. 4:168-179.
23. Haider, S. S., Hasan, M., Hasan, S. N., Khan, S. R., and Ali, S. F. 1981. Regional effects of sulfur dioxide exposure on the guinea pig brain lipids, lipid peroxidation and lipase activity. Neurotoxicology 2:443-450.
24. Hirsch-Ernst, K. I., Schlaefer, K., Bauer, D., Heder, A. F., and Kahl, G. F. 2001. Repression of phenobarbital-dependent CYP2B1 mRNA induction by reactive oxygen species in primary rat hepatocyte cultures. Mol. Pharmacol. 59:1402-1409.
25. Irizar, A., and Ioannides, C. 1998. Marked inhibition of hepatic cytochrome P450 activity in cholesterol-induced atherosclerosis in rabbits. Toxicology. 126:179-193.
26. Koksal, N., Yildirim, Z., Gokirmak, M., Hasanoglu, H. C., Mehmet, N., and Avci, H. 2003. The role of nitric oxide and cytokines in asthma-like syndrome induced by sulfur dioxide exposure in agricultural environment. Clin. Chim. Acta 336:115-122.
27. 3) in vitro. Hum. Exp. Toxicol. 17:600-605.
28. Lester, M. R. 1995. Sulfite sensitivity: Significance in human health. J. Am. Coll. Nutr. 14:229-232.
29. Lewis, D. F. V., Lake, B. G., Dickins, M., Eddershaw, P. J., Tarbit, M. H., and Goldfarb, P. S. 1999. Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: Evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4. Xenobiotica 29:361-393.
30. Marchand, L. L., Wilkinson, G. R., and Wilkens, L. R. 1999. Genetic and dietary predictors of CYP2E1 activity: A phenotyping study in Hawaii Japanese using chlorzoxazone1. Cancer Epidemiol. Biomarkers Prev. 8:495-500.
31. Meng, Z. 2003. Oxidative damage of sulfur dioxide on various organs of mice: Sulfur dioxide is a systemic oxidative damage agent. Inhal. Toxicol. 15:181-195.
32. Meng, Z., and Zhang, L. 1990. Chromosomal aberrations and sister-chromatid exchanges in lymphocytes of workers exposed to sulphur dioxide. Mutat. Res. 241:15-20.
33. Meng, Z., and Zhang, B. 2003. Oxidation damage of sulfur dioxide inhalation on brains and livers of mice. Environ. Toxicol. Pharmacol. 13:1-8.
34. Meng, Z., Qin, G., Zhang, B., Geng, H., Bai, Q., Bai, W., and Liu, C. 2003. Oxidative damage of sulfur dioxide inhalation on lungs and hearts of mice. Environ. Res. 93:285-292.
35. Meng, Z., Qin, G., Zhang, B., and Bai, J. 2004. DNA damaging effects of sulfur dioxide derivatives in cells from various organs of mice. Mutagenesis. 19:465-468.
36. Meng, Z., Li, R., and Zhang, X. 2005a. Levels of sulfite in three organs from mice exposed to sulfur dioxide. Inhal. Toxicol. 17:309-313.
37. Meng, Z., Liu, Y., and Wu, D. 2005b. Effect of sulfur dioxide inhalation on cytokine levels in lungs and serum of mice. Inhal. Toxicol. 17:303-307.
38. Meng, Z., Qin, G., and Zhang, B. 2005c. DNA damage in mice treated with sulfur dioxide by inhalation. Environ. Mol. Mutagen. 46:150-155.
39. Milosevic, N., Schawalder, H., and Maier, P. 1999. Kupffer cell-mediated differential down-regulation of cytochrome P450 metabolism in rat hepatocytes. Eur. J. Pharmacol. 368:75-87.
40. Morel, Y., and Barouki, R. 1999. Repression of gene expression by oxidative stress. Biochem. J. 342:481-496.
41. Morgan, E. T. 1997. Regulation of cytochromes P450 during inflammation and infection. Drug Metab. Rev. 29:1129-1188.
42. Morgan, E. T. Thomas, K. B., Swanson, R., Vales, T., Hwang, J., and Wright, K. 1994. Selective suppression of cytochrome P-450 gene expression by interleukins 1 and 6 in rat liver. Biochim. Biophys. Acta Gene Struct. Express. 1219:475-483.
43. Morris, D. L., and Davila, J. C. 1996. Analysis of rat cytochrome P450 isoenzyme expression using semi-quantitative reverse transcriptase-polymerase chain reaction (RT-PCR). Biochem. Pharmacol. 52:781-792.
44. Omura, T., and Sato, R. 1964. The carbon monoxide-binding pigment of liver microsomes. J. Biol. Chem. 239:2370-2378.
45. Pahan, K., Smith, B. T., Singh, A. K., and Singh, I. 1997. Cytochrome P-450 2E1 in rat liver peroxisomes: Downregulation by ischemia/reperfusion- induced oxidative stress. Free Radical Biol. Med. 23:963-971.
46. Parke, D. V., and Ioannides, C. 1994. The effects of nutrition on chemical toxicity. Drug Metab. Rev. 26:739-765.
47. Pelletier, M., Lavastre, V., and Girard, D. 2002. Activation of human epithelial lung a549 cells by the pollutant sodium sulfite: Enhancement of neutrophil adhesion. Toxicol. Sci. 69:210-216.
48. Poet, T. S., Brendel, K., and Halpert, J. R. 1994. Inactivation of cytochromes P450 2B protects against cocaine-mediated toxicity in rat liver slices. Toxicol. Appl. Pharmacol. 126:26-32.
49. Pous, C., Giroud, J. -P., Damais, C., Raichvarg, D., and Chauvelot-Moachon, L. 1990. Effect of recombinant human interleukin-1β and tumor necrosis factor α on liver cytochrome P-450 and serum a-1-acid glycoprotein concentrations in the rat. Drug Metab. Dispos. 18:467-470.
50. Qin, G., and Meng, Z. 2005. Effect of sulfur dioxide inhalation on CYP1A1 and CYP1A2 in rat liver and lung. Toxicol. Lett. 160:34-42.
51. Rall, D. P. 1974. Review of the health effects of sulfur oxides. Environ. Health Perspect. 8:97-121.
52. Ratthe, C., Pelletier, M., Roberge, C. J., and Girard, D. 2002. Activation of human neutrophils by the pollutant sodium sulfite: Effect on cytokine production, chemotaxis, and cell surface expression of cell adhesion molecules. Clin. Immunol. 105:169-175.
53. Reinke, L. A., and Mayer, M. J. 1985. p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol. Drug Metab. Dispos. 13:548-552.
54. Renton, K. W. 1981. Depression of hepatic cytochrome P450 dependent mixed function oxidases during infection with encephalomyocarditis. Biochem. Pharmacol. 30:2333-2336.
55. Renton, K. W., and Knickle, L. C. 1990. Regulation of hepatic cytochrome P-450 during infectious disease. Can. J. Physiol. Pharmacol. 68:777-781.
56. Shapiro, R. 1977. Genetic effects of bisulfite (sulfur dioxide). Mutat. Res. 38:149-176.
57. Stanley, L. A., Adams, D. J., Lindsay, R., Meehan, R. R., Liao, W., and Wolf, C. R. 1988. Potentiation and suppression of mouse liver cytochrome P-450 isozymes during the acute-phase response induced by bacterial endotoxin. Eur. J. Biochem. 174:31-36.
58. Stiborová, M., Hansílsová, H., and Frei, E. 1996. Metabolism of carcinogenic N-nitroso-N-methylaniline by purified cytochromes P450 2B1 and 2B2. Cancer. Lett. 110:11-17.
59. World Health Organization. 1987. Air quality guidelines for Europe. pp. 338-359. WHO Regional Publications (European series No. 23) Copenhagen: WHO.
60. Yamazaki, H., Inoue, K., Hashimoto, M., and Shimada, T. 1999. Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes. Arch. Toxicol. 73:65-70.
61. Yargicoglu, P., Agar, A., Gumusluoriob, S., Bilmen, S., and Oguz, Y. 1999. Age-related alterations in antioxidant enzymes, lipid peroxide levels, and somatosensory-evoked potentials: Effect of sulfur dioxide. Arch. Environ. Contam. Toxicol. 37:554-560.