메뉴 건너뛰기




Volumn 52, Issue 5, 1996, Pages 781-792

Analysis of rat cytochrome P450 isoenzyme expression using semi-quantitative reverse transcriptase-polymerase chain reaction (RT-PCR)

Author keywords

enzyme; liver; P450; rat; RT PCR

Indexed keywords

BETA NAPHTHOFLAVONE; CLOFIBRATE; CYTOCHROME P450 ISOENZYME; DEXAMETHASONE; MESSENGER RNA; METYRAPONE; PHENOBARBITAL;

EID: 0030582433     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00390-5     Document Type: Article
Times cited : (94)

References (69)
  • 1
    • 0023061373 scopus 로고
    • P450 genes: Structure, evolution, and regulation
    • 1. Nebert DW and Gonzalez FJ, P450 genes: Structure, evolution, and regulation. Annu Rev Biochem 56: 945-993, 1987.
    • (1987) Annu Rev Biochem , vol.56 , pp. 945-993
    • Nebert, D.W.1    Gonzalez, F.J.2
  • 2
    • 0024236331 scopus 로고
    • The molecular biology of cytochrome P450s
    • 2. Gonzalez FJ, The molecular biology of cytochrome P450s. Pharmacol Rev 40: 243-288, 1989.
    • (1989) Pharmacol Rev , vol.40 , pp. 243-288
    • Gonzalez, F.J.1
  • 3
    • 0023951396 scopus 로고
    • Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy
    • 3. Guengerich FP, Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res 48: 2946-2954, 1988.
    • (1988) Cancer Res , vol.48 , pp. 2946-2954
    • Guengerich, F.P.1
  • 4
    • 0025688972 scopus 로고
    • Role of cytochromes P450 in drug metabolism and hepatotoxicity
    • 4. Watkins PB, Role of cytochromes P450 in drug metabolism and hepatotoxicity. Semin Liver Dis 10: 235-250, 1990.
    • (1990) Semin Liver Dis , vol.10 , pp. 235-250
    • Watkins, P.B.1
  • 5
    • 0025067462 scopus 로고
    • Molecular genetics of the P-450 superfamily
    • 5. Gonzalez FJ, Molecular genetics of the P-450 superfamily. Pharmacol Ther 45: 1-38, 1990.
    • (1990) Pharmacol Ther , vol.45 , pp. 1-38
    • Gonzalez, F.J.1
  • 6
    • 0025273823 scopus 로고
    • Enzymatic oxidation of xenobiotic chemicals
    • 6. Guengerich FP, Enzymatic oxidation of xenobiotic chemicals. Crit Rev Biochem Mol Biol 25: 97-153, 1990.
    • (1990) Crit Rev Biochem Mol Biol , vol.25 , pp. 97-153
    • Guengerich, F.P.1
  • 7
    • 0026035519 scopus 로고
    • Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
    • 7. Guengerich FP, Kim D-H and Iwasaki M, Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4: 168-179, 1991.
    • (1991) Chem Res Toxicol , vol.4 , pp. 168-179
    • Guengerich, F.P.1    Kim, D.-H.2    Iwasaki, M.3
  • 9
    • 0022357068 scopus 로고
    • Ethoxy-, pentoxy-and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450
    • 9. Burke MD, Thompson S, Elcombe CR, Halpert J, Haaparanta T and Mayer RT, Ethoxy-, pentoxy-and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450. Biochem Pharmacol 34: 3337-3345, 1985.
    • (1985) Biochem Pharmacol , vol.34 , pp. 3337-3345
    • Burke, M.D.1    Thompson, S.2    Elcombe, C.R.3    Halpert, J.4    Haaparanta, T.5    Mayer, R.T.6
  • 10
    • 0028106482 scopus 로고
    • Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver
    • 10. Burke MD, Thompson S, Weaver RJ, Wolf CR and Mayer RT, Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. Biochem Pharmacol 48: 923-936, 1994.
    • (1994) Biochem Pharmacol , vol.48 , pp. 923-936
    • Burke, M.D.1    Thompson, S.2    Weaver, R.J.3    Wolf, C.R.4    Mayer, R.T.5
  • 11
    • 0024559081 scopus 로고
    • Reduction of 7-alkoxyresorufins by NADPH-cytochrome P450 reductase and its differential effects on their O-dealkylation by rat liver microsomal cytochrome P450
    • 11. Dutton DR and Parkinson A, Reduction of 7-alkoxyresorufins by NADPH-cytochrome P450 reductase and its differential effects on their O-dealkylation by rat liver microsomal cytochrome P450. Arch Biochem Biophys 268: 617-629, 1989.
    • (1989) Arch Biochem Biophys , vol.268 , pp. 617-629
    • Dutton, D.R.1    Parkinson, A.2
  • 12
    • 0022350885 scopus 로고
    • Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat
    • 12. Lubet RA, Mayer RT, Cameron JW, Nims RW, Burke MD, Wolff T and Guengerich FP, Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. Arch Biochem Biophys 238: 43-48, 1985.
    • (1985) Arch Biochem Biophys , vol.238 , pp. 43-48
    • Lubet, R.A.1    Mayer, R.T.2    Cameron, J.W.3    Nims, R.W.4    Burke, M.D.5    Wolff, T.6    Guengerich, F.P.7
  • 13
    • 0025316491 scopus 로고
    • Induction of hepatic cytochrome P-450 mediated alkoxyresorufin O-dealkylase activities in different species by prototype P-450 inducers
    • 13. Lubet RA, Syi J-L, Nelson JO and Nims RW, Induction of hepatic cytochrome P-450 mediated alkoxyresorufin O-dealkylase activities in different species by prototype P-450 inducers. Chem Biol Interact 75: 325-339, 1990.
    • (1990) Chem Biol Interact , vol.75 , pp. 325-339
    • Lubet, R.A.1    Syi, J.-L.2    Nelson, J.O.3    Nims, R.W.4
  • 14
    • 0027179679 scopus 로고
    • Methoxyresorufin and benzyloxyresorufin: Substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse
    • 14. Nerurkar PV, Park SS, Thomas PE, Nims RW and Lubert RA, Methoxyresorufin and benzyloxyresorufin: Substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem Pharmacol 46: 933-943, 1993.
    • (1993) Biochem Pharmacol , vol.46 , pp. 933-943
    • Nerurkar, P.V.1    Park, S.S.2    Thomas, P.E.3    Nims, R.W.4    Lubert, R.A.5
  • 15
    • 0026334526 scopus 로고
    • Production and purification of antibodies against rat liver P450 enzymes
    • 15. Parkinson A and Gemzik B, Production and purification of antibodies against rat liver P450 enzymes. Methods Enzymol 206: 233-245, 1991.
    • (1991) Methods Enzymol , vol.206 , pp. 233-245
    • Parkinson, A.1    Gemzik, B.2
  • 17
    • 0025997062 scopus 로고
    • Rapid small-scale RNA isolation from tissue culture cells
    • 17. Xie WQ and Rothblum LI, Rapid small-scale RNA isolation from tissue culture cells. Biotechniques 11, 326-327, 1991.
    • (1991) Biotechniques , vol.11 , pp. 326-327
    • Xie, W.Q.1    Rothblum, L.I.2
  • 18
    • 0021157894 scopus 로고
    • Detection and purification of cytochrome P-450 in animal tissues with monoclonal antibodies
    • 18. Cheng KC, Gelboin HV, Song B-J, Park S-S and Friedman FK, Detection and purification of cytochrome P-450 in animal tissues with monoclonal antibodies. J Biol Chem 259: 12279-12284, 1984.
    • (1984) J Biol Chem , vol.259 , pp. 12279-12284
    • Cheng, K.C.1    Gelboin, H.V.2    Song, B.-J.3    Park, S.-S.4    Friedman, F.K.5
  • 19
    • 0026022309 scopus 로고
    • Tissue acylation by the chlorofluorcarbon substitute 2,2-dichloro-1,1,1-trifluoroethane
    • 19. Harris JW, Pohl LR, Martin JL and Anders MW, Tissue acylation by the chlorofluorcarbon substitute 2,2-dichloro-1,1,1-trifluoroethane. Proc Natl Acad Sci USA 88: 1407-1410, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1407-1410
    • Harris, J.W.1    Pohl, L.R.2    Martin, J.L.3    Anders, M.W.4
  • 20
    • 0025160864 scopus 로고
    • Inhibition of ethanol-inducible cytochrome P450IIE1 by 3-amino-1,2,4-triazole
    • 20. Koop DR, Inhibition of ethanol-inducible cytochrome P450IIE1 by 3-amino-1,2,4-triazole. Chem Res Toxicol 3: 377-383, 1990.
    • (1990) Chem Res Toxicol , vol.3 , pp. 377-383
    • Koop, D.R.1
  • 21
    • 0022494453 scopus 로고
    • Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a
    • 21. Koop DR, Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Mol Pharmacol 29: 399-404, 1986.
    • (1986) Mol Pharmacol , vol.29 , pp. 399-404
    • Koop, D.R.1
  • 22
    • 0021112308 scopus 로고
    • Regio-and stereoselective metabolism of two C19 steroids by five highly-purified and reconstituted rat hepatic cytochrome P-450 isozymes
    • 22. Wood AW, Ryan DE, Thomas PE and Levin W, Regio-and stereoselective metabolism of two C19 steroids by five highly-purified and reconstituted rat hepatic cytochrome P-450 isozymes. J Biol Chem 258: 8839-8847, 1983.
    • (1983) J Biol Chem , vol.258 , pp. 8839-8847
    • Wood, A.W.1    Ryan, D.E.2    Thomas, P.E.3    Levin, W.4
  • 24
    • 0023778344 scopus 로고
    • Inhibition of steroid 5α-reductase and its effects on testosterone hydroxylation by rat liver microsomal cytochrome P-450
    • 24. Sonderfan AJ and Parkinson A, Inhibition of steroid 5α-reductase and its effects on testosterone hydroxylation by rat liver microsomal cytochrome P-450. Arch Biochem Biophys 265: 208-218, 1988.
    • (1988) Arch Biochem Biophys , vol.265 , pp. 208-218
    • Sonderfan, A.J.1    Parkinson, A.2
  • 25
    • 77957188094 scopus 로고
    • A convenient method for the determination of hepatic lauric acid ω-oxidation based on solvent partition
    • 25. Giera DD and van Lier RB L, A convenient method for the determination of hepatic lauric acid ω-oxidation based on solvent partition. Fundam Appl Toxicol 16: 348-355, 1991.
    • (1991) Fundam Appl Toxicol , vol.16 , pp. 348-355
    • Giera, D.D.1    Van Lier, R.B.L.2
  • 26
    • 0023875216 scopus 로고
    • Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation
    • 26. Romano MC, Straub KM, Yodis LAP, Eckardt RD and Newton JF, Determination of microsomal lauric acid hydroxylase activity by HPLC with flow-through radiochemical quantitation. Anal Biochem 170: 83-93, 1988.
    • (1988) Anal Biochem , vol.170 , pp. 83-93
    • Romano, M.C.1    Straub, K.M.2    Yodis, L.A.P.3    Eckardt, R.D.4    Newton, J.F.5
  • 27
  • 28
    • 0020434524 scopus 로고
    • Purification and characterization of liver microsomal cytochromes P-450: Electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes from rats treated with phenobarbital or β-naphthoflavone
    • 28. Guengerich FP, Dannan GA, Wright ST, Martin MV and Kaminsky LS, Purification and characterization of liver microsomal cytochromes P-450: Electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes from rats treated with phenobarbital or β-naphthoflavone. Biochemistry 21: 6019-6030, 1982.
    • (1982) Biochemistry , vol.21 , pp. 6019-6030
    • Guengerich, F.P.1    Dannan, G.A.2    Wright, S.T.3    Martin, M.V.4    Kaminsky, L.S.5
  • 29
    • 0020374942 scopus 로고
    • Phenobarbital-induced rat liver cytochrome P-450: Purification and characterization of two closely related isozymic forms
    • 29. Waxman DJ and Walsh C, Phenobarbital-induced rat liver cytochrome P-450: Purification and characterization of two closely related isozymic forms. J Biol Chem 257: 10446-10457, 1982.
    • (1982) J Biol Chem , vol.257 , pp. 10446-10457
    • Waxman, D.J.1    Walsh, C.2
  • 30
    • 0020368740 scopus 로고
    • Purification, characterization, and regulation of five rat hepatic microsomal cytochrome P-450 isozymes
    • 30. Ryan DE, Thomas PE, Reik LM and Levin W, Purification, characterization, and regulation of five rat hepatic microsomal cytochrome P-450 isozymes. Xenobiotica 11: 727-744, 1982.
    • (1982) Xenobiotica , vol.11 , pp. 727-744
    • Ryan, D.E.1    Thomas, P.E.2    Reik, L.M.3    Levin, W.4
  • 31
    • 0344950089 scopus 로고
    • Primary structure of a cytochrome P-450: Coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver
    • 31. Fujii-Kuriyama Y, Mizukami Y, Kawajiri K, Sogawa K and Muramatsu M, Primary structure of a cytochrome P-450: Coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver. Proc Natl Acad Sci USA 79: 2793-2797, 1982.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 2793-2797
    • Fujii-Kuriyama, Y.1    Mizukami, Y.2    Kawajiri, K.3    Sogawa, K.4    Muramatsu, M.5
  • 32
    • 0020573715 scopus 로고
    • A cytochrome P-450 multigene family: Characterization of a gene activated by phenobarbital administration
    • 32. Atchison M and Adesnik M, A cytochrome P-450 multigene family: Characterization of a gene activated by phenobarbital administration. J Biol Chem 258: 11285-11295, 1983.
    • (1983) J Biol Chem , vol.258 , pp. 11285-11295
    • Atchison, M.1    Adesnik, M.2
  • 33
    • 0020601879 scopus 로고
    • Cloned cytochrome P-450 cDNA, nucleotide sequence, and homology to multiple phenobarbital-mduced mRNA species
    • 33. Kumar A, Raphael C and Adesnik M, Cloned cytochrome P-450 cDNA, nucleotide sequence, and homology to multiple phenobarbital-mduced mRNA species. J Biol Chem 258: 11280-11284, 1983.
    • (1983) J Biol Chem , vol.258 , pp. 11280-11284
    • Kumar, A.1    Raphael, C.2    Adesnik, M.3
  • 35
    • 0022419376 scopus 로고
    • Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver
    • 35. Suwa Y, Mizukami Y, Sogawa K and Fujii-Kuriyama Y, Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver. J Biol Chem 260: 7980-7984, 1985.
    • (1985) J Biol Chem , vol.260 , pp. 7980-7984
    • Suwa, Y.1    Mizukami, Y.2    Sogawa, K.3    Fujii-Kuriyama, Y.4
  • 36
    • 0023573045 scopus 로고
    • Gene structure of cytochrome P-450 (M-1) specifically expressed in male rat liver
    • 36. Morishima N, Yoshioka H, Higashi Y, Sogawa K and Fujii-Kuriyama Y, Gene structure of cytochrome P-450 (M-1) specifically expressed in male rat liver. Biochemistry 26: 8279-8285, 1987.
    • (1987) Biochemistry , vol.26 , pp. 8279-8285
    • Morishima, N.1    Yoshioka, H.2    Higashi, Y.3    Sogawa, K.4    Fujii-Kuriyama, Y.5
  • 37
    • 0023694134 scopus 로고
    • cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15β-hydroxylation of steroid sulfates
    • 37. Zaphiropoulos PG, Mode A, Strom A, Moller C, Fernandez C and Gustafsson J-A, cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15β-hydroxylation of steroid sulfates. Proc Natl Acad Sci USA 85: 4214-4217, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4214-4217
    • Zaphiropoulos, P.G.1    Mode, A.2    Strom, A.3    Moller, C.4    Fernandez, C.5    Gustafsson, J.-A.6
  • 38
    • 0026567713 scopus 로고
    • Oxidative and reductive metabolism by cytochrome P450 2D1
    • 38. Koop DR, Oxidative and reductive metabolism by cytochrome P450 2D1. FASEB J 6: 724-739, 1992.
    • (1992) FASEB J , vol.6 , pp. 724-739
    • Koop, D.R.1
  • 40
    • 0027310190 scopus 로고
    • Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid
    • 40. Park KS, Sohn DH, Veech RL and Song BJ, Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid. Eur J Pharmacol 248: 7-14, 1993.
    • (1993) Eur J Pharmacol , vol.248 , pp. 7-14
    • Park, K.S.1    Sohn, D.H.2    Veech, R.L.3    Song, B.J.4
  • 41
    • 0027439096 scopus 로고
    • CYP1A1 mRNA levels as a human biomarker: Use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes
    • 41. Vanden-Heuvel JP, Clark GC, Thompson CL, McCoy Z, Miller CR, Lucier GW and Bell DA, CYP1A1 mRNA levels as a human biomarker: Use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes. Carcinogenesis 14: 2003-2006, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 2003-2006
    • Vanden-Heuvel, J.P.1    Clark, G.C.2    Thompson, C.L.3    McCoy, Z.4    Miller, C.R.5    Lucier, G.W.6    Bell, D.A.7
  • 42
    • 0027762691 scopus 로고
    • Identification of cytochromes P450 1A2, 2A1, 2C7, 2E1 in rat glioma C6 cell line by RT-PCR and specific restriction enzyme digestion
    • 42. Geng J and Strobel HW, Identification of cytochromes P450 1A2, 2A1, 2C7, 2E1 in rat glioma C6 cell line by RT-PCR and specific restriction enzyme digestion. Biochem Biophys Res Commun 197: 1179-1184, 1993.
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 1179-1184
    • Geng, J.1    Strobel, H.W.2
  • 43
    • 0028104347 scopus 로고
    • Pretranslational induction of cytochrome P4501A enzymes by naphthoflavone and 3-methylcholanthrene occurs in different liver zones
    • 43. Oinonen T, Saarikoski S, Husgafvel-Pursiainen K, Hirvonen A and Lindros KO, Pretranslational induction of cytochrome P4501A enzymes by naphthoflavone and 3-methylcholanthrene occurs in different liver zones. Biochem Pharmacol 48: 2189-2197, 1994.
    • (1994) Biochem Pharmacol , vol.48 , pp. 2189-2197
    • Oinonen, T.1    Saarikoski, S.2    Husgafvel-Pursiainen, K.3    Hirvonen, A.4    Lindros, K.O.5
  • 44
    • 0029121348 scopus 로고
    • 3-Methylcholanthrene and pyridine effects on CYP1A1 and CYP1A2 expression in rat renal tissue
    • 44. Kim H, Reddy S and Novak RF, 3-Methylcholanthrene and pyridine effects on CYP1A1 and CYP1A2 expression in rat renal tissue. Drug Metab Dispos 23: 818-824, 1995.
    • (1995) Drug Metab Dispos , vol.23 , pp. 818-824
    • Kim, H.1    Reddy, S.2    Novak, R.F.3
  • 46
    • 0029092796 scopus 로고
    • Identification of inducible mixed function oxidase system in rat glioma C6 cell line
    • 46. Geng J and Strobel HW, Identification of inducible mixed function oxidase system in rat glioma C6 cell line. J Neurochem 65: 554-563, 1995.
    • (1995) J Neurochem , vol.65 , pp. 554-563
    • Geng, J.1    Strobel, H.W.2
  • 47
    • 0003003173 scopus 로고
    • Competitive PCR for quantitation of mRNA
    • Eds. Innis MA, Gelfand DH, Sninsky JJ and White TJ, Academic Press, San Diego, CA
    • 47. Gilliland G, Perrin S and Bunn HF, Competitive PCR for quantitation of mRNA. In: PCR Protocol: A Guide to Methods and Applications (Eds. Innis MA, Gelfand DH, Sninsky JJ and White TJ), pp. 60-69. Academic Press, San Diego, CA, 1990.
    • (1990) PCR Protocol: A Guide to Methods and Applications , pp. 60-69
    • Gilliland, G.1    Perrin, S.2    Bunn, H.F.3
  • 48
    • 0002809580 scopus 로고
    • Quantitative PCR
    • Eds. Innis MA, Gelfand DH, Sninsky JJ and White TJ, Academic Press, San Diego, CA
    • 48. Wang AM and Mark DF, Quantitative PCR. In: PCR Protocols: A Guide to Methods and Applications (Eds. Innis MA, Gelfand DH, Sninsky JJ and White TJ), pp. 70-75. Academic Press, San Diego, CA, 1990.
    • (1990) PCR Protocols: A Guide to Methods and Applications , pp. 70-75
    • Wang, A.M.1    Mark, D.F.2
  • 49
    • 0022869269 scopus 로고
    • Complementary DNA and protein sequences of ethanol-inducible rat and human P-450s: Transcriptional and post-transcriptional regulation of the rat enzyme
    • 49. Song BJ, Gelboin HV, Park SS, Yang CS and Gonzalez FJ, Complementary DNA and protein sequences of ethanol-inducible rat and human P-450s: Transcriptional and post-transcriptional regulation of the rat enzyme. J Biol Chem 261: 16689-16697, 1986.
    • (1986) J Biol Chem , vol.261 , pp. 16689-16697
    • Song, B.J.1    Gelboin, H.V.2    Park, S.S.3    Yang, C.S.4    Gonzalez, F.J.5
  • 50
    • 0023854490 scopus 로고
    • Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures
    • 50. Eliasson E, Johansson I and Ingelman-Sundberg M, Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures. Biochem Biophys Res Commun 150: 436-443, 1988.
    • (1988) Biochem Biophys Res Commun , vol.150 , pp. 436-443
    • Eliasson, E.1    Johansson, I.2    Ingelman-Sundberg, M.3
  • 51
    • 0028226507 scopus 로고
    • A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes
    • 51. Weaver RJ, Thompson S, Smith G, Dickins M, Elcombe CR, Mayer RT and Burke MD, A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes. Biochem Pharmacol 47: 763-773, 1994.
    • (1994) Biochem Pharmacol , vol.47 , pp. 763-773
    • Weaver, R.J.1    Thompson, S.2    Smith, G.3    Dickins, M.4    Elcombe, C.R.5    Mayer, R.T.6    Burke, M.D.7
  • 52
    • 0025738537 scopus 로고
    • Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities
    • 52. Wortelboer HM, de Kruif CA, van Iersel AAJ, Falke HE, Noordhoek J and Blaauboer BJ, Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities. Biochem Pharmacol 42: 381-390, 1991.
    • (1991) Biochem Pharmacol , vol.42 , pp. 381-390
    • Wortelboer, H.M.1    De Kruif, C.A.2    Van Iersel, A.A.J.3    Falke, H.E.4    Noordhoek, J.5    Blaauboer, B.J.6
  • 53
    • 0021947032 scopus 로고
    • Regulation of rat hepatic cytochrome P-450: Age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex specific isoenzymes
    • 53. Waxman DJ, Dannan GA and Guengerich FP, Regulation of rat hepatic cytochrome P-450: Age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex specific isoenzymes. Biochemistry 24: 4409-4417, 1985.
    • (1985) Biochemistry , vol.24 , pp. 4409-4417
    • Waxman, D.J.1    Dannan, G.A.2    Guengerich, F.P.3
  • 54
    • 0022975388 scopus 로고
    • 4-steroid 5α-reductase, flavin-containing monoxygenase, and sex-specific cytochromes P-450
    • 4-steroid 5α-reductase, flavin-containing monoxygenase, and sex-specific cytochromes P-450. J Biol Chem 261: 10728-10735, 1986.
    • (1986) J Biol Chem , vol.261 , pp. 10728-10735
    • Dannan, G.H.1    Guengerich, F.P.2    Waxman, D.J.3
  • 55
    • 0021912401 scopus 로고
    • Sexual differentiation of cytochrome P-450 in rat liver: Evidence for a constitutive isozyme as the male-specific 16α-hydroxylase
    • 55. Morgan ET, MacGeoch C and Gustafsson J-A, Sexual differentiation of cytochrome P-450 in rat liver: Evidence for a constitutive isozyme as the male-specific 16α-hydroxylase. Mol Pharmacol 27: 471-479, 1986.
    • (1986) Mol Pharmacol , vol.27 , pp. 471-479
    • Morgan, E.T.1    MacGeoch, C.2    Gustafsson, J.-A.3
  • 56
    • 0023024793 scopus 로고
    • Effects of growth hormone and ectopic transplantation of pituitary gland on sex-specific forms of cytochrome P-450 and testosterone and drug oxidations in rat liver
    • 56. Kato R, Yamazoe Y, Shimada M, Murayama N and Kamataki T, Effects of growth hormone and ectopic transplantation of pituitary gland on sex-specific forms of cytochrome P-450 and testosterone and drug oxidations in rat liver. J Biochem 100: 895-902, 1986.
    • (1986) J Biochem , vol.100 , pp. 895-902
    • Kato, R.1    Yamazoe, Y.2    Shimada, M.3    Murayama, N.4    Kamataki, T.5
  • 57
    • 0023019202 scopus 로고
    • Effects of hypophysectomy and growth hormone treatment on sex-specific forms of cytochrome P-450 in relation to drug and steroid metabolisms in rat liver microsomes
    • 57. Yamazoe Y, Shimada M, Kamataki T and Kato R, Effects of hypophysectomy and growth hormone treatment on sex-specific forms of cytochrome P-450 in relation to drug and steroid metabolisms in rat liver microsomes. Japn J Pharmacol 42: 371-382, 1986.
    • (1986) Japn J Pharmacol , vol.42 , pp. 371-382
    • Yamazoe, Y.1    Shimada, M.2    Kamataki, T.3    Kato, R.4
  • 58
    • 0026661071 scopus 로고
    • Gene-specific oligonucleotide probes for α, μ, π, and microsomal rat glutathione-s-transferases: Analysis of liver transferase expression and its modulation by hepatic enzyme inducers and platinum anticancer drugs
    • 58. Waxman DJ, Sundseth SS, Srivastava PK and Lapenson DP, Gene-specific oligonucleotide probes for α, μ, π, and microsomal rat glutathione-S-transferases: Analysis of liver transferase expression and its modulation by hepatic enzyme inducers and platinum anticancer drugs. Cancer Res 52: 5797-5802, 1992.
    • (1992) Cancer Res , vol.52 , pp. 5797-5802
    • Waxman, D.J.1    Sundseth, S.S.2    Srivastava, P.K.3    Lapenson, D.P.4
  • 60
    • 0028308486 scopus 로고
    • Induction of microsomal and peroxisomal enzymes by dehydroepiandrosterone and its reduced metabolite in rats
    • 60. Prough RA, Webb SJ, Wu HQ, Lapenson DP and Waxman DJ, Induction of microsomal and peroxisomal enzymes by dehydroepiandrosterone and its reduced metabolite in rats. Cancer Res 54: 2878-2886, 1994.
    • (1994) Cancer Res , vol.54 , pp. 2878-2886
    • Prough, R.A.1    Webb, S.J.2    Wu, H.Q.3    Lapenson, D.P.4    Waxman, D.J.5
  • 61
    • 0028272231 scopus 로고
    • Deduced amino acid sequence of a murine cytochrome P-450 CYP4a protein: Developmental and hormonal regulation in liver and kidney
    • 61. Henderson CJ, Bammler T and Wolf CR, Deduced amino acid sequence of a murine cytochrome P-450 CYP4a protein: Developmental and hormonal regulation in liver and kidney. Biochim Biophys Acta 1200: 182-190, 1994.
    • (1994) Biochim Biophys Acta , vol.1200 , pp. 182-190
    • Henderson, C.J.1    Bammler, T.2    Wolf, C.R.3
  • 62
    • 0022968060 scopus 로고
    • Pregnenolone 16α-carbonitrile-inducible P-450 gene family: Gene conversion and differential regulation
    • 62. Gonzalez FJ, Song B-J and Hardwick JP, Pregnenolone 16α-carbonitrile-inducible P-450 gene family: Gene conversion and differential regulation. Mol Cell Biol 6: 2969-2976, 1986.
    • (1986) Mol Cell Biol , vol.6 , pp. 2969-2976
    • Gonzalez, F.J.1    Song, B.-J.2    Hardwick, J.P.3
  • 64
    • 0021885288 scopus 로고
    • Induction of cytochrome P-450 by phenobarbital is mediated at the level of transcription
    • 64. Pike SF, Shephard EA, Rabin BR and Phillips IR, Induction of cytochrome P-450 by phenobarbital is mediated at the level of transcription. Biochem Pharmacol 34: 2489-2494, 1985.
    • (1985) Biochem Pharmacol , vol.34 , pp. 2489-2494
    • Pike, S.F.1    Shephard, E.A.2    Rabin, B.R.3    Phillips, I.R.4
  • 65
    • 0025348354 scopus 로고
    • Immunochemical quantitation of cytochrome P450IA and IIB subfamilies in the livers of metyrapone-treated rats. Relevance to the ability of metyrapone to prevent the loss of cytochrome P450 in rat hepatocyte culture
    • 65. Shean K and Paine AJ. Immunochemical quantitation of cytochrome P450IA and IIB subfamilies in the livers of metyrapone-treated rats. Relevance to the ability of metyrapone to prevent the loss of cytochrome P450 in rat hepatocyte culture. Biochem J 267: 715-719, 1990.
    • (1990) Biochem J , vol.267 , pp. 715-719
    • Shean, K.1    Paine, A.J.2
  • 66
    • 0028203555 scopus 로고
    • Induction of rat hepatic glucocorticoid-inducible cytochrome P450 3A by metyrapone
    • 66. Wright MC, Paine AJ, Skett P and Auld R, Induction of rat hepatic glucocorticoid-inducible cytochrome P450 3A by metyrapone. J Steroid Biochem Mol Biol 48: 271-276, 1994.
    • (1994) J Steroid Biochem Mol Biol , vol.48 , pp. 271-276
    • Wright, M.C.1    Paine, A.J.2    Skett, P.3    Auld, R.4
  • 67
    • 0020589426 scopus 로고
    • Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone 16α-carbonitrile: Characterization of its mRNA, gene, and induction response
    • 67. Hardwick JP, Gonzalez FJ and Kasper CB, Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone 16α-carbonitrile: Characterization of its mRNA, gene, and induction response. J Biol Chem 258: 10182-10186, 1983.
    • (1983) J Biol Chem , vol.258 , pp. 10182-10186
    • Hardwick, J.P.1    Gonzalez, F.J.2    Kasper, C.B.3
  • 68
    • 0022006744 scopus 로고
    • Demonstration in multiple species of inducible hepatic cytochromes P-450 and their mRNAs related to the glucocorticoid-inducible cytochrome P-450 of the rat
    • 68. Wrighton SA, Schuetz EG, Watkins PB, Maurel P, Barwick J, Bailey BS, Hartle HT, Young B and Guzelian PS, Demonstration in multiple species of inducible hepatic cytochromes P-450 and their mRNAs related to the glucocorticoid-inducible cytochrome P-450 of the rat. Mol Pharmacol 28: 312-321, 1985.
    • (1985) Mol Pharmacol , vol.28 , pp. 312-321
    • Wrighton, S.A.1    Schuetz, E.G.2    Watkins, P.B.3    Maurel, P.4    Barwick, J.5    Bailey, B.S.6    Hartle, H.T.7    Young, B.8    Guzelian, P.S.9
  • 69
    • 0023124674 scopus 로고
    • Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids: Transcriptional and post-transcriptional regulation
    • 69. Simmons DL, McQuiddy P and Kasper CB, Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids: Transcriptional and post-transcriptional regulation. J Biol Chem 262: 326-332, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 326-332
    • Simmons, D.L.1    McQuiddy, P.2    Kasper, C.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.