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Volumn 6, Issue 4, 2006, Pages 325-331

The use of thalidomide in myeloma therapy as an effective anticancer drug

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DEXAMETHASONE; IMMUNOMODULATING AGENT; MELPHALAN; THALIDOMIDE;

EID: 33745500974     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800906777441762     Document Type: Review
Times cited : (15)

References (84)
  • 1
    • 0033806822 scopus 로고    scopus 로고
    • Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival
    • Sze, D. M.; Toellner, K. M.; Garcia de Vinuesa, C.; Taylor, D. R.; MacLennan, I. C. Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival. J. Exp. Med. 2000, 192, 813-821.
    • (2000) J. Exp. Med. , vol.192 , pp. 813-821
    • Sze, D.M.1    Toellner, K.M.2    Garcia De Vinuesa, C.3    Taylor, D.R.4    MacLennan, I.C.5
  • 2
    • 0033947559 scopus 로고    scopus 로고
    • Multiple myeloma - Evolving concepts of biology and treatment
    • Joshua, D. E.; Gibson, J. Multiple myeloma - evolving concepts of biology and treatment. Aust. N. Z. J. Med. 2000, 30, 311-318.
    • (2000) Aust. N. Z. J. Med. , vol.30 , pp. 311-318
    • Joshua, D.E.1    Gibson, J.2
  • 3
    • 0028775544 scopus 로고
    • The treatment of multiple myeloma
    • Alexanian, R.; Dimopoulos, M. The treatment of multiple myeloma. N. Engl. J. Med. 1994, 330, 484-489.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 484-489
    • Alexanian, R.1    Dimopoulos, M.2
  • 4
    • 49749219257 scopus 로고
    • Thalidomide and congenital abnormalities
    • Lenz, W. Thalidomide and congenital abnormalities. Lancet 1962, 1, 45.
    • (1962) Lancet , vol.1 , pp. 45
    • Lenz, W.1
  • 5
    • 84883833410 scopus 로고
    • Thalidomide in the Treatment of Lepra Reactions
    • Sheskin, J. Thalidomide in the Treatment of Lepra Reactions. Clin. Pharmacol. Ther. 1965, 40, 303-306.
    • (1965) Clin. Pharmacol. Ther. , vol.40 , pp. 303-306
    • Sheskin, J.1
  • 6
    • 0036168049 scopus 로고    scopus 로고
    • A review of angiogenesis and anti-angiogenic therapy in hematologic malignancies
    • Rajkumar, S.; Mesa, R. A,; Tefferi, A. A review of angiogenesis and anti-angiogenic therapy in hematologic malignancies. J. Hematother. Stem Cell Res. 2002, 11, 33-47.
    • (2002) J. Hematother. Stem Cell Res. , vol.11 , pp. 33-47
    • Rajkumar, S.1    Mesa, R.A.2    Tefferi, A.3
  • 7
    • 84883832143 scopus 로고
    • Clinical experiences with thalidomide in patients with cancer
    • Grabstald, H.; Golbey, R. Clinical experiences with thalidomide in patients with cancer. Clin. Pharmacol. Ther. 1965, 40, 298-302.
    • (1965) Clin. Pharmacol. Ther. , vol.40 , pp. 298-302
    • Grabstald, H.1    Golbey, R.2
  • 8
  • 12
    • 0642276742 scopus 로고    scopus 로고
    • Treatment of plasma cell dyscrasias with thalidomide and its derivatives
    • Dimopoulos, M.; Anagnostopoulos, A.; Weber, D. Treatment of plasma cell dyscrasias with thalidomide and its derivatives. J. Clin. Oncol. 2003, 21, 4444-4454.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 4444-4454
    • Dimopoulos, M.1    Anagnostopoulos, A.2    Weber, D.3
  • 13
    • 0037716629 scopus 로고    scopus 로고
    • Management of multiple myeloma: A systematic review and critical appraisal of published studies
    • Kumar, A.; Loughran, T.; Alsina, M.; Durie, B. G.; Djulbegovic, B. Management of multiple myeloma: a systematic review and critical appraisal of published studies. Lancet Oncol. 2003, 4, 293-304.
    • (2003) Lancet Oncol. , vol.4 , pp. 293-304
    • Kumar, A.1    Loughran, T.2    Alsina, M.3    Durie, B.G.4    Djulbegovic, B.5
  • 16
    • 85047682765 scopus 로고    scopus 로고
    • The combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is feasible and can be an option for relapsed/refractory multiple myeloma
    • Garcia-Sanz, R.; Gonzalez-Fraile, M.I.; Sierra, M.; Lopez, C.; Gonzalez, M.; San Miguel, J. F. The combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is feasible and can be an option for relapsed/refractory multiple myeloma. Hematol. J. 2002, 3, 43-48.
    • (2002) Hematol. J. , vol.3 , pp. 43-48
    • Garcia-Sanz, R.1    Gonzalez-Fraile, M.I.2    Sierra, M.3    Lopez, C.4    Gonzalez, M.5    San Miguel, J.F.6
  • 17
    • 0036909461 scopus 로고    scopus 로고
    • Use of melphalan, thalidomide, and dexamethasone in treatment of refractory and relapsed multiple myeloma
    • Srkalovic, G.; Elson, P.; Trebisky, B.; Karam, M. A.; Hussein, M. A. Use of melphalan, thalidomide, and dexamethasone in treatment of refractory and relapsed multiple myeloma. Med. Oncol. Tumor Pharmacother. 2002, 19, 219-226.
    • (2002) Med. Oncol. Tumor Pharmacother. , vol.19 , pp. 219-226
    • Srkalovic, G.1    Elson, P.2    Trebisky, B.3    Karam, M.A.4    Hussein, M.A.5
  • 18
    • 0033168605 scopus 로고    scopus 로고
    • Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
    • Corral, L. G.; Haslett, P. A.; Muller, G. W.; Chen, R.; Wong, L. M.; Ocampo, C. J.; Patterson, R. T.; Stirling, D. I.; Kaplan, G. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J. Immunol. 1999, 163, 380-386.
    • (1999) J. Immunol. , vol.163 , pp. 380-386
    • Corral, L.G.1    Haslett, P.A.2    Muller, G.W.3    Chen, R.4    Wong, L.M.5    Ocampo, C.J.6    Patterson, R.T.7    Stirling, D.I.8    Kaplan, G.9
  • 21
    • 0032920883 scopus 로고    scopus 로고
    • Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity
    • Parman, T.; Wiley, M. J.; Wells, P. G. Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity. Nat. Med. 1999, 5, 582-585.
    • (1999) Nat. Med. , vol.5 , pp. 582-585
    • Parman, T.1    Wiley, M.J.2    Wells, P.G.3
  • 23
    • 0035672117 scopus 로고    scopus 로고
    • Response to thalidomide in progressive multiple myeloma is not mediated by inhibition of angiogenic cytokine secretion
    • Neben, K.; Moehler, T.; Kraemer, A.; Benner, A.; Egerer, G.; Ho, A. D.; Goldschmidt, H. Response to thalidomide in progressive multiple myeloma is not mediated by inhibition of angiogenic cytokine secretion. Br. J. Haematol. 2001, 115, 605-608.
    • (2001) Br. J. Haematol. , vol.115 , pp. 605-608
    • Neben, K.1    Moehler, T.2    Kraemer, A.3    Benner, A.4    Egerer, G.5    Ho, A.D.6    Goldschmidt, H.7
  • 24
    • 0032100604 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent
    • Bauer, K.; Dixon, S. C.; Figg, W. D. Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent. Biochem. Pharmacol. 1998, 55, 1827-1834.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1827-1834
    • Bauer, K.1    Dixon, S.C.2    Figg, W.D.3
  • 25
    • 0033105537 scopus 로고    scopus 로고
    • Cell adhesion mediated drug resistance (CAM-DR): Role of integrins and resistance to apoptosis in human myeloma cell lines
    • Damiano, J. S.; Cress, A. E.; Hazlehurst, L. A.; Shtil, A. A.; Dalton, W. S. Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines. Blood 1999, 93, 1658-1667.
    • (1999) Blood , vol.93 , pp. 1658-1667
    • Damiano, J.S.1    Cress, A.E.2    Hazlehurst, L.A.3    Shtil, A.A.4    Dalton, W.S.5
  • 26
    • 0036499140 scopus 로고    scopus 로고
    • Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines
    • Shain, K. H.; Landowski, T. H.; Dalton, W. S. Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines. J. Immunol. 2002, 168, 2544-2553.
    • (2002) J. Immunol. , vol.168 , pp. 2544-2553
    • Shain, K.H.1    Landowski, T.H.2    Dalton, W.S.3
  • 27
    • 0034618384 scopus 로고    scopus 로고
    • Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR)
    • Hazlehurst, L. A.; Damiano, J. S.; Buyuksal, I.; Pledger, W. J.; Dalton, W. S. Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR). Oncogene 2000, 19, 4319-4327.
    • (2000) Oncogene , vol.19 , pp. 4319-4327
    • Hazlehurst, L.A.1    Damiano, J.S.2    Buyuksal, I.3    Pledger, W.J.4    Dalton, W.S.5
  • 28
    • 0026080801 scopus 로고
    • Thalidomide selectively inhibits tumour necrosis factor alpha production by stimulated human monocytes
    • Sampaio, E. P.; Sarno, E. N.; Galilly, R.; Cohn, Z. A.; Kaplan, G. Thalidomide selectively inhibits tumour necrosis factor alpha production by stimulated human monocytes. J. Exp. Med. 1991, 173, 699-703.
    • (1991) J. Exp. Med. , vol.173 , pp. 699-703
    • Sampaio, E.P.1    Sarno, E.N.2    Galilly, R.3    Cohn, Z.A.4    Kaplan, G.5
  • 29
    • 0027304271 scopus 로고
    • The influence of thalidomide on the clinical and immunologic manifestation of erythema nodosum leprosum
    • Sampaio, E. P.; Kaplan, G.; Miranda, A.; Nery, J. A.; Miguel, C. P.; Viana, S. M.; Sarno, E. N. The influence of thalidomide on the clinical and immunologic manifestation of erythema nodosum leprosum. J. Infect. Dis. 1993, 168, 408-414.
    • (1993) J. Infect. Dis. , vol.168 , pp. 408-414
    • Sampaio, E.P.1    Kaplan, G.2    Miranda, A.3    Nery, J.A.4    Miguel, C.P.5    Viana, S.M.6    Sarno, E.N.7
  • 31
    • 0027133422 scopus 로고
    • Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion
    • Uchiyama, H.; Barut, B. A.; Mohrbacher, A. F.; Chauhan, D.; Anderson, K. C. Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion. Blood 1993, 82, 3712-3720.
    • (1993) Blood , vol.82 , pp. 3712-3720
    • Uchiyama, H.1    Barut, B.A.2    Mohrbacher, A.F.3    Chauhan, D.4    Anderson, K.C.5
  • 33
    • 0014020464 scopus 로고
    • Effect of thalidomide on the graft versus host reaction
    • Field, E. O.; Gibbs, J. E.; Tucker, D. F.; Hellmann, K. Effect of thalidomide on the graft versus host reaction. Nature 1966, 211, 1308-1310.
    • (1966) Nature , vol.211 , pp. 1308-1310
    • Field, E.O.1    Gibbs, J.E.2    Tucker, D.F.3    Hellmann, K.4
  • 35
    • 0022457890 scopus 로고
    • Treatment and prevention of acute graft-versus-host disease with thalidomide in a rat model
    • Vogelsang, G. B.; Hess, A. D.; Gordon, G.; Santos, G. W. Treatment and prevention of acute graft-versus-host disease with thalidomide in a rat model. Transplantation 1986, 41, 644-647.
    • (1986) Transplantation , vol.41 , pp. 644-647
    • Vogelsang, G.B.1    Hess, A.D.2    Gordon, G.3    Santos, G.W.4
  • 37
    • 0024951605 scopus 로고
    • Thalidomide for the therapy of graft-versus-host disease following allogeneic bone marrow transplantation
    • McCarthy, D. M.; Kanfer, E. J.; Barrett, A. J. Thalidomide for the therapy of graft-versus-host disease following allogeneic bone marrow transplantation. Biomed. Pharmacother. 1989, 43, 693-697.
    • (1989) Biomed. Pharmacother. , vol.43 , pp. 693-697
    • McCarthy, D.M.1    Kanfer, E.J.2    Barrett, A.J.3
  • 38
    • 0025724048 scopus 로고
    • Immunosuppressive properties of thalidomide. Inhibition of in vitro lymphocyte proliferation alone and in combination with cyclosporine or FK506
    • Keenan, R. J.; Eiras, G.; Burckart, G. J.; Stuart, R. S.; Hardesty, R. L.; Vogelsang, G.; Griffith, B. P.; Zeevi, A. Immunosuppressive properties of thalidomide. Inhibition of in vitro lymphocyte proliferation alone and in combination with cyclosporine or FK506. Transplantation 1991, 52, 908-910.
    • (1991) Transplantation , vol.52 , pp. 908-910
    • Keenan, R.J.1    Eiras, G.2    Burckart, G.J.3    Stuart, R.S.4    Hardesty, R.L.5    Vogelsang, G.6    Griffith, B.P.7    Zeevi, A.8
  • 42
    • 0033997269 scopus 로고    scopus 로고
    • Malignancy: Idiotypic Immune Targeting of Multiple Myeloma
    • Lim, S. H.; Wen, Y. J.; Ling, M. Malignancy: Idiotypic Immune Targeting of Multiple Myeloma. Hematol. 2000, 4, 471-477.
    • (2000) Hematol. , vol.4 , pp. 471-477
    • Lim, S.H.1    Wen, Y.J.2    Ling, M.3
  • 45
    • 0033664310 scopus 로고    scopus 로고
    • Idiotype immunity (natural and vaccine-induced) in early stage multiple myeloma
    • Osterborg, A.; Henriksson, L.; Mellstedt, H. Idiotype immunity (natural and vaccine-induced) in early stage multiple myeloma. Acta Oncol. 2000, 39, 797-800.
    • (2000) Acta Oncol. , vol.39 , pp. 797-800
    • Osterborg, A.1    Henriksson, L.2    Mellstedt, H.3
  • 46
    • 0033120389 scopus 로고    scopus 로고
    • Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma - A feasibility study
    • Reichardt, V. L.; Okada, C. Y.; Liso, A.; Benike, C. J.; Stockerl-Goldstein, K. E.; Engleman, E. G.; Blume, K. G.; Levy, R. Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma - A feasibility study. Blood 1999, 93, 2411-2419.
    • (1999) Blood , vol.93 , pp. 2411-2419
    • Reichardt, V.L.1    Okada, C.Y.2    Liso, A.3    Benike, C.J.4    Stockerl-Goldstein, K.E.5    Engleman, E.G.6    Blume, K.G.7    Levy, R.8
  • 50
    • 0034125194 scopus 로고    scopus 로고
    • Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies
    • Trojan, A.; Schultze, J. L.; Witzens, M.; Vonderheide, R. H.; Ladetto, M.; Donovan, J. W.; Gribben, J. G. Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies. Nat. Med. 2000, 6, 667-672.
    • (2000) Nat. Med. , vol.6 , pp. 667-672
    • Trojan, A.1    Schultze, J.L.2    Witzens, M.3    Vonderheide, R.H.4    Ladetto, M.5    Donovan, J.W.6    Gribben, J.G.7
  • 54
    • 0035282736 scopus 로고    scopus 로고
    • Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma
    • Lim, S. H.; Wang, Z.; Chiriva-Internati, M.; Xue, Y. Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma. Blood 2001, 97, 1508-1510.
    • (2001) Blood , vol.97 , pp. 1508-1510
    • Lim, S.H.1    Wang, Z.2    Chiriva-Internati, M.3    Xue, Y.4
  • 55
    • 0028365244 scopus 로고
    • Thalidomide and the immune system. 3. Simultaneous up- and down-regulation of different integrin receptors on human white blood cells
    • Nogueira, A. C.; Neubert, R.; Helge, H.; Neubert, D. Thalidomide and the immune system. 3. Simultaneous up- and down-regulation of different integrin receptors on human white blood cells. Life Sci. 1994, 55, 77-92.
    • (1994) Life Sci. , vol.55 , pp. 77-92
    • Nogueira, A.C.1    Neubert, R.2    Helge, H.3    Neubert, D.4
  • 56
    • 0028928143 scopus 로고
    • The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures
    • McHugh, S. M.; Rifkin, I. R.; Deighton, J.; Wilson, A. B.; Lachmann, P. J.; Lockwood, C. M.; Ewan, P. W. The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures. Clin. Exp. Immunol. 1995, 99, 160-167.
    • (1995) Clin. Exp. Immunol. , vol.99 , pp. 160-167
    • McHugh, S.M.1    Rifkin, I.R.2    Deighton, J.3    Wilson, A.B.4    Lachmann, P.J.5    Lockwood, C.M.6    Ewan, P.W.7
  • 61
    • 33745123242 scopus 로고    scopus 로고
    • Clonally Expanded T Cells in Myeloma with a Late Memory/Effector Phenotype Are Associated with Improved Survival
    • Sze, D. M. -Y.; Brown, R; Yang, S.; Ho, J. P.; Gibson, J.; Fazekas de St Groth, B.; Basten, A.; Joshua, D. Clonally Expanded T Cells in Myeloma with a Late Memory/Effector Phenotype Are Associated with Improved Survival. Blood 2004, 102, 927a.
    • (2004) Blood , vol.102
    • Sze, D.M.-Y.1    Brown, R.2    Yang, S.3    Ho, J.P.4    Gibson, J.5    Fazekas De St Groth, B.6    Basten, A.7    Joshua, D.8
  • 63
    • 0032100486 scopus 로고    scopus 로고
    • Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset
    • Haslett, P. A. J.; Corral, L. G.; Albert, M.; Kaplan, G. thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset. J. Exp. Med. 1998, 187, 1885-1892.
    • (1998) J. Exp. Med. , vol.187 , pp. 1885-1892
    • Haslett, P.A.J.1    Corral, L.G.2    Albert, M.3    Kaplan, G.4
  • 64
    • 0015029994 scopus 로고
    • An internally-controlled double blind trial of thalidomide in severe erythema nodosum leprosum
    • Waters, M. F. An internally-controlled double blind trial of thalidomide in severe erythema nodosum leprosum. Lepr. Rev. 1971, 42, 26-42.
    • (1971) Lepr. Rev. , vol.42 , pp. 26-42
    • Waters, M.F.1
  • 67
    • 33745487084 scopus 로고    scopus 로고
    • Increased number of TCR Vβ expansions in patients on Thalidomide maintenance therapy provides further evidence of the immunomodulatory action of Thalidomide
    • Murray, A.; Brown, R.; Ho, P. J.; Sze, D.; Gibson, J.; Joshua, D. Increased number of TCR Vβ expansions in patients on Thalidomide maintenance therapy provides further evidence of the immunomodulatory action of Thalidomide. Hematologica 2005, 90(S1), 182.
    • (2005) Hematologica , vol.90 , Issue.S1 , pp. 182
    • Murray, A.1    Brown, R.2    Ho, P.J.3    Sze, D.4    Gibson, J.5    Joshua, D.6
  • 69
    • 0026061865 scopus 로고
    • Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28
    • Fraser, J. D.; Irving, B. A.; Crabtree, G. R.; Weiss, A. Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science 1991, 251, 313-316.
    • (1991) Science , vol.251 , pp. 313-316
    • Fraser, J.D.1    Irving, B.A.2    Crabtree, G.R.3    Weiss, A.4
  • 72
    • 0024602819 scopus 로고
    • Interleukin-1 and tumour necrosis factor stimulate the formation of human osteoclast like cells in vitro
    • Pfeilschifter, J.; Chenu, C.; Bird, A.; Mundy, G. R.; Roodman, G. D. Interleukin-1 and tumour necrosis factor stimulate the formation of human osteoclast like cells in vitro. J. Bone Miner Res. 1989, 4, 113-118.
    • (1989) J. Bone Miner Res. , vol.4 , pp. 113-118
    • Pfeilschifter, J.1    Chenu, C.2    Bird, A.3    Mundy, G.R.4    Roodman, G.D.5
  • 73
    • 0345534770 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: A possible role for HGF in myeloma-associated osteolytic bone disease
    • Hjertner, O.; Torgersen, M. L.; Seidel, C.; Hjorth-Hansen, H.; Waage, A.; Borset, M.; Sundan, A. Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: a possible role for HGF in myeloma-associated osteolytic bone disease. Blood 1999, 94, 3883-3888.
    • (1999) Blood , vol.94 , pp. 3883-3888
    • Hjertner, O.1    Torgersen, M.L.2    Seidel, C.3    Hjorth-Hansen, H.4    Waage, A.5    Borset, M.6    Sundan, A.7
  • 75
    • 0030041147 scopus 로고    scopus 로고
    • Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B
    • Chauhan, D.; Uchiyama, H.; Akbarali, Y.; Urashima, M.; Yamamoto, K.; Libermann, T. A.; Anderson, K. C. Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B. Blood 1996, 87, 1104-1112.
    • (1996) Blood , vol.87 , pp. 1104-1112
    • Chauhan, D.1    Uchiyama, H.2    Akbarali, Y.3    Urashima, M.4    Yamamoto, K.5    Libermann, T.A.6    Anderson, K.C.7
  • 79
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • Gabrilovich, D. I.; Chen, H. L.; Girgis, K. R.; Cunningham, H. T.; Meny, G. M.; Nadaf, S.; Kavanaugh, D.; Carbone, D. P. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat. Med. 1996, 2, 1096-1103.
    • (1996) Nat. Med. , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3    Cunningham, H.T.4    Meny, G.M.5    Nadaf, S.6    Kavanaugh, D.7    Carbone, D.P.8
  • 81
    • 0035895083 scopus 로고    scopus 로고
    • Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment
    • Giuliani, N.; Bataille, R.; Mancini, C.; Lazzaretti, M.; Barille, S. Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment. Blood 2001, 98, 3527-3533.
    • (2001) Blood , vol.98 , pp. 3527-3533
    • Giuliani, N.1    Bataille, R.2    Mancini, C.3    Lazzaretti, M.4    Barille, S.5
  • 84
    • 0035383761 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand
    • Han, J. H.; Choi, S. J.; Kurihara, N.; Koide, M.; Oba, Y.; Roodman, G. D. Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand. Blood 2001, 97, 3349-3353.
    • (2001) Blood , vol.97 , pp. 3349-3353
    • Han, J.H.1    Choi, S.J.2    Kurihara, N.3    Koide, M.4    Oba, Y.5    Roodman, G.D.6


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