Application of genomics to the pork industry

Journal of Animal Science

Volumn 83, Issue , 2005, Pages E1-E8

  Van Der Steen, H A M ^a   Prall, G F W ^a   Plastow, G S ^b  

^a Sygen International   (United States)

^b Kingston Bagpuize   (United Kingdom)

Author keywords

Genomics; Growth; Health; Meat Quality; Pigs

Indexed keywords

EID: 33745495090     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/2005.8313_supplE1x     Document Type: Conference Paper

References (42)

1. Buys, N. 2003. IGF2: The use of paternally expressed QTLinfluencing muscle mass in marker assisted selection in commercial pig populations. Proc. Natl. Swine Fed. Conf. Annu. Mtg. Available: ww.nsif.com/Conferences/pdg/IGF2.pdf. Accessed July 24, 2004.
2. Carlborg, O¨ ., and C. S. Haley. 2004. Epistasis: Too often neglected in complex trait studies? Nature Rev. Genet. 5:618-625. Ciobanu, D. C., J. W. M. Bastiaansen, S. M. Lonergan, H. Thomsen,
3. J. C. M. Dekkers, G. Plastow, and M. Rothschild. 2004. New alleles in calpastatin gene are associated with meat quality traits in pigs. J. Anim. Sci 82:2829-2839. Ciobanu, D., J. Bastiaansen, M. Malek, J. Helm, J. Woollard, G.
4. Plastow, and M. Rothschild. 2001. Evidence for new alleles in the protein kinase AMP-activated, γ3 subunit gene associated with low glycogen content in pig skeletal muscle and improved meat quality. Genetics 159:1151-1162.
5. Ciobanu, D. C., S. M. Lonergan, J. W. M. Bastiaansen, J. R. Woollard, M. Malek, E. J. Huff-Lonergan, G. S. Plastow, and M. F. Rothschild. 2002. Evidence for new alleles in calpastatin gene associated with meat quality traits in pigs. Pages 355-358 in Proc. 7th World Cong. Genet. Appl. Livest. Prod. INRA, Castanet-Tolosan, France.
6. Delgado, J. V., G. Plastow, L. Alderson, C. Chevalet, and R. Cardellino. 2003. Pig biodiversity. Arch. Zootec. 52:127-128.
7. De Vries, A. G., A. Sosnicki, J. P. Garnier, and G. S. Plastow. 1998. The role of major genes and DNA technology in selection for meat quality in pigs. Meat Sci. 48(Suppl. 1):S245-S255.
8. De Vries, A. G., H. H. Timm, E. R. Wilson, V. Keller, and G. S. Plastow. 1997. An effective DNA marker for the acid meat problem. Pages 340 in Book of Abstracts 48th Annu. Mtg. EAAP, Vienna, Austria, Wageningen Pers. Wageningen.
9. Frydendahl, K., T. K. Jensen, J. S. Andersen, M. Fredholm, and G. Evans. 2003. Association between the porcine Escherichia coli F18 receptor genotype and phenotype and susceptibility to colonisation and postweaning diarrhoea caused by E. coli O138:F18. Vet. Microbiol. 93:39-51.
10. Fujii, J., K. Otsu, F. Zorzato, S. De Leon, V. K. Khanna, J. E. Weiler, P. J. O (tm)Brien, and D. H. MacLennan. 1991. Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science 253:448-451.
11. Galina, L., I. Blanco, A. Canals, S. Dornan, C. Sargent, L. Huang, M. Mellencamp, J. Ullrich, V. Spehr, P. Seltzer, and G. Evans. 2002. PathoCHIP: Identification of genes critical in host/pathogen interactions during H. parasuis infection. Pages 31-32 in Proc. Allen D. Leman Swine Conf. Univ. of Minnesota, St. Paul.
12. Giuffra, E., A. To¨rnsten, S. Marklund, E. Bongcam-Rudloff, P. Chardon, J. M. H. Kijas, S. Anderson, A. Archibald, and L. Andersson. 2002. A large duplication associated with dominant white color in pigs originated by homologous recombination between LINE elements flanking KIT. Mamm. Genome 13:569-577.
13. Hernandez-Sanchez, J., P. Visscher, G. S. Plastow, and C. Haley. 2003. Candidate gene analysis for quantitative traits using the transmission disequuilibrium test: The example of the melanocortin 4-receptor in pigs. Genetics 164:637-644.
14. Jeon, J.-T., O. Carlborg. A To¨rnsten, E. Giuffra, V. Amarger, P. Chardon, L. Andersson-Eklund, K. Andersson, I. Hansson, K. Lundstrom, and L. Andersson. 1999. A paternally expressed QTL affecting skeletal and cardiac muscle mass in pigs maps to the IGF2 locus. Nature Genet. 21:157-158.
15. Johansson Moller, M., R. Chaudhary, E. Hellmen, B. Hoyheim, B. Cowdhary, and L. Andersson. 1996. Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor. Mamm. Genome 7:822-830.
16. Jungst, S., E. Wilson, M. Rothschild, C. Booher, T. Pastor, B. Fields,
17. and G. Plastow. 2001. Effects of the Porcine Melanocortin 4 Receptor gene on growth rate, feed conversion and carcass composition of pigs sired by PIC337 or PIC408 boars. J. Anim. Sci. 79(Suppl. 1):192. (Abstr.)
18. Kim, K. S., J. J. Kim, J. C. M. Dekkers, and M. F. Rothschild. 2004a. Polar overdominant inheritance of a DLK1 polymorphism is associated with growth and fatness in pigs. Mamm. Genome 15:552-559.
19. Kim, K. S., N. Larsen, T. Short, G. S. Plastow, and M. F. Rothschild. 2000. A Missense variant of the porcine melanocortin-4 receptor (MC4R) gene is associated with fatness, growth and feed intake traits. Mamm. Genome 11:131-135.
20. Kim, K. S., J. M. Reecy, W. H. Hsu, L. L. Anderson, and M. F. Rothschild. 2004b. Functional and phylogenetic analyses of a melanocortin-4 receptor mutation in domestic pigs. Domest. Anim. Endocrinol. 26:75-86.
21. Kim. K. S., H. Thomsen, J. Bastiaansen, N. T. Nguyen, J. C. M. Dekkers, G. S. Plastow, and M. F. Rothschild. 2004c. A comparative study of obesity QTL and candidate genes in the pig: A model organism for human obesity. Obesity Res. (In press)
22. Knap, P. W., A. A. Sosnicki, R. E. Klont, and A. Lacoste, 2002. Simultaneous improvement of meat quality and growth and carcass traits in pigs. Pages 339-346 in Proc. 7th World Cong. Genet. Appl. Livest. Prod. INRA, Castanet-Tolosan, France.
23. Maltin, C., and G. S. Plastow. 2004. Functional genomics and proteomics in relation to muscle tissue. Pages 267-296 in Muscle Development in Livestock. M. F. W. te Pas, M. E. Everts and H. P. Haagsman, ed. CAB Int., Wallingford, U.K.
24. Marklund, S., J. Kijas, H. Rodriquez-Martinez, L. Ronnstrand, K. Funa, M. Moller, D. Lange, I. Edfors-Lilja, and L. Andersson. 1998. Molecular basis for dominant white phenotype in pigs. Genome Res. 8:826-833.
25. Meijerink, E., S. Neuenschwander, R. Fries, A. Dinter, H. U. Bertschinger, G. Stranzinger, and P. Voegeli. 2000. A DNA polymorphism influencing α(1,2) fucosyltransferase activity of the pig FUT1 enzyme determines susceptibility of small intestinal epithelium to Escherichia coli F18 adhesion. Immunogenetics 52:129-36.
26. Meuwissen, T. H. E., and M. E. Goddard. 1996. The use of marker haplotypes in animal breeding schemes. Genet. Sel. Evol. 28:161-176.
27. Meuwissen T. H. E, and M. E. Goddard. 2000 Fine mapping of quantitative trait loci using linkage disequilibria with closely linked marker loci. Genetics 155:421-430.
28. Milan, D., J. T. Jeon, C. Looft, V. Amarger, A. Robic, M. Thelander, C. Rogel-Gaillard, S. Paul, N. Iannuccelli, L. Rask, H. Ronne, K. Lundstrom, N. Reinsch, J. Gellin, E. Kalm, P. L. Roy, P.
29. Chardon, and L. Andersson. 2000. A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle. Science 288:1248-1251.
30. Nezer, C., L. Moreau, B. Brouwers, W. Coppieters, J. Detilleux, R. Hanset, L. Karim, A. Kvasz, P. Leroy, and M. Georges. 1999. An imprinted QTL with major effect on muscle mass and fat deposition maps to the IGF2 locus in pigs. Nature Genet. 21:155-156.
31. Oliveira, S., L. Galina, I. Blanco, A. Canals, and C. Pijoan. 2003. Naturally-farrowed, artificially-reared pigs as an alternative model for experimental infection by Haemophilus parasuis. Can. J. Vet. Res. 67:146-150.
32. Plastow, G. S. 2003a. Genetic approaches for the improvement of health and productivity. Pig J. 52:195-200.
33. Plastow, G. S. 2003b. The changing world of genomics and its impact on the pork chain. Adv. Pork Prod. 14:67-71.
34. Plastow, G. S. 2004. The role of breeding companies in delivering change: Lessons from the pig industry. Pages 1-6 in AgBiotech-Net Proceedings. CAB Int., Wallingford, U.K.
35. Plastow, G. S., D. S. Carrio´n, M. Gil, J. A. Garcı´a-Regueiro, M. Fonti Furnols, M. Gispert, M. A. Oliver, A. Velarde, M. D. Gua` rdia, M. Horto´s, M. A. Ruis, C. Sa´rraga, I. Dı´az, A. Valero, A. Sosnicki, R. Klont, S. Dornan, J. M. Wilkinson, G. Evans, C. Sargent, G. Davey, D. Connolly, B. Houeix, C. M. Maltin, H. E. Hayes, V. Anandavijayan, A. Foury, N. Geverink, M. Cairns, R. E. Tilley, P. Morme`de, and S. C. Blott. 2005. Quality pork genes and meat production. Meat Sci. 70:409-421.
36. Plastow, G., S. Sasaki, T.-P. Yu, N. Deeb, G. Prall, K. Siggens, and E. Wilson. 2003. Practical application of DNA markers for genetic improvement. Proc. Natl. Swine Fed. Conf. Annu. Mtg. Available: www.nsif.com/Conferences/pdf/PracticalDNAMarkers.pdf. Accessed July 24, 2004.
37. Rothschild, M. F., C. Jacobson, D. A. Vaske, C. K. Tuggle, L. Wang, T. Short, G. R. Eckardt, S. Sasaki, A. Vincent, D. G. McLaren, O. Southwood, H. van der Steen, A. Mileham, and G. Plastow. 1996. The estrogen receptor locus is associated with a major gene influencing litter size in pigs. Proc. Natl. Acad. Sci. USA 93:201-205.
38. Short, T. H., M. F. Rothschild, O. I. Southwood, D. G. McLaren, A. de Vries, H. van der Steen, G. R. Eckardt, C. K. Tuggle, J. Helm, D. A. Vaske, A. J. Mileham, and G. S. Plastow. 1997. Effect of estrogen receptor locus on reproduction and production traits in four commercial pig lines. J. Anim. Sci. 75:3138-3142.
39. Van Laere, A.-S., M. Nguyen, M. Braunschweig, C. Nezer, C. Collette, L. Moreau, A. L. Archibald, C. S. Haley, N. Buys, M. Tally, G.
40. Andersson, M. Georges, and L. Andersson. 2003. A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig. Nature 425:832-836.
41. Vansickle, J. 2001. Genetically resistant line stops E. coli cold. Natl. Hog Farmer 46:10-12.
42. Wilson, M., O. I. Southwood, and G. S. Plastow. 2004. The effect of a polymorphism in the MC4R gene within a Meishan synthetic line of pigs. Page 227 in Proc. Annu. Br. Soc. Anim. Sci. Mtg. Br. Soc. Anim. Sci., Penicuik, U.K.