Inhibition of p21 modifies the response of cortical proximal tubules to cisplatin in rats

American Journal of Physiology - Renal Physiology

Volumn 291, Issue 1, 2006, Pages

  Zhou, Hua ^a   Fujigaki, Yoshihide ^a   Kato, Akihiko ^a,b   Miyaji, Takehiko ^a   Yasuda, Hideo ^a   Tsuji, Takayuki ^a   Yamamoto, Tatsuo ^a   Yonemura, Katsuhiko ^a   Hishida, Akira ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHIZUOKA CANCER CENTER   (Japan)

Author keywords

Acute renal failure; Cisplatin; Renal cortex

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CISPLATIN; FLUORESCEIN ISOTHIOCYANATE; MESSENGER RNA; PROTEIN P21;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOWN REGULATION; DRUG INHIBITION; KIDNEY MEDULLA; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE NECROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; UPREGULATION; UREA NITROGEN BLOOD LEVEL;

EID: 33745352070     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00324.2004     Document Type: Article

References (30)

1. Butler M, Stecker K, and Bennett CF. Cellular distribution of phosphorothioate oligodeoxynucleotides in normal rodent tissues. Lab Invest 77: 379-388, 1997.
2. Celis JE and Madsen P. Increased nuclear cyclin/P.CNA antigen staining of non-S-phase transformed human amnion cells engaged in nucleotide excision DNA repair. FEBS Lett 209: 277-283, 1986.
3. Cojocel C and Thomson MS. Impairment of the renal p-aminohippurate transport induced by 6-hydroxydopamine. J Pharm Pharmacol 55: 669-674, 2003.
4. Dentino M, Luft FC, Yum MN, Williams SD, and Einhorn LH. Long term effect of cis-diamminedichloride platinum (CDDP) on renal function and structure in man. Cancer 41: 1274-1281,1978.
5. Dobyan DC, Levi J, Jacobs C, Kosek J, and Weiner MW. Mechanism of cis-platinum nephrotoxicity. II. Morphologic observations. J Pharmacol Exp Ther 213: 551-556, 1980.
6. Fan S, Chang JK, Smith ML, Duba D, Fornace, AJ Jr, and O'Connor PM. Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard. Oncogene 14: 2127-2136, 1997.
7. Gillett CE, Barnes DM, and Camplejohn RS. Comparison of three cell cycle associated antigens as markers of proliferative activity and prognosis in breast carcinoma. J Clin Pathol 46: 1126-1128, 1993.
8. Guinee DG Jr, van Zee B, and Houghton DC. Clinically silent progressive renal tubulointerstitial disease during cisplatin chemotherapy. Cancer 71: 4050-4054, 1993.
9. Honda N and Sudo M. Resistance to uranyl-acetate-induced acute renal failure in rabbits: renal function and morphology. In: Acute Renal Failure, edited by Eliahou HE. London: Libbet, 1982, p. 105-107.
10. Kim YK, Choi TR, Kwon CH, Kim JH, Woo JS, Jung JS. Beneficial effect of pentoxifylline on cisplatin-induced acute renal failure in rabbits. Ren Fail 25: 909-922, 2003.
11. Liu H and Baliga R. Cytochrome P450 2E1 null mice provide novel protection against cisplatin-induced nephrotoxicity and apoptosis. Kidney Int 63: 1687-1696, 2003.
12. Megyesi J, Safirstein RL, and Price PM. Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure. J Clin Invest 101: 777-782, 1998.
13. Megyesi J, Andrade L, Vieira JM Jr, Safirstein RL, and Price PM. Positive effect of the induction of p21WAF1/CIP1 on the course of ischemic acute renal failure. Kidney Int 60: 2164-2172, 2001.
14. Miyaji T, Kato A, Yasuda H, Fujigaki Y, and Hishida A. Role of the increase in p21 in cisplatin-induced acute renal failure in rats. J Am Soc Nephrol 12: 900-908, 2001.
15. Nowak G, Price PM, and Schnellmann RG. Lack of a functional p21WAF1/CIP1 gene accelerates caspase-independent apoptosis induced by cisplatin in renal cells. Am J Physiol Renal Physiol 285: F440-F450, 2003.
16. Oberbauer R, Schreiner GF, and Meyer TW. Renal uptake of an 18-mer phosphorothioate oligonucleotide. Kidney Int 48: 1226-1232, 1995.
17. Price PM, Safirstein RL, and Megyesi J. Protection of renal cells from cisplatin toxicity by cell cycle inhibitors. Am J Physiol Renal Physiol 286: F378-F384, 2004.
18. Reznik LV and Gambaryan SP. Protective effect of antiinflammatory corticosteroid triamcinolone in cisplatin nephrotoxicity. Ren Physiol Biochem 17: 50-56, 1994.
19. Ruan S, Okcu MF, Ren JP, Chiao P, Andreeff M, Levin V, and Zhang W. Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin. Cancer Res 58: 1538-1543, 1998.
20. 3H-labeled oligonucleotides. Comparison of a phosphodiester and a phosphorothioate. Mol Pharmacol 45: 932-43, 1994.
21. Sano K, Fujigaki Y, Miyaji T, Ikegaya N, Ohishi K, Yonemura K, and Hishida A:. Role of apoptosis in uranyl acetate-induced acute renal failure and acquired resistance to uranyl acetate. Kidney Int 57: 1560-1570, 2000.
22. Sato N, Mizumoto K, Maehara N, Kusumoto M, Nishio S, Urashima T, Ogawa T, and Tanaka M. Enhancement of drug-induced apoptosis by antisense oligodeoxynucleotides targeted against Mdm2 and p21WAF1/CIP1. Anticancer Res 20: 837-842, 2000.
23. Shankland SJ and Wolf G. Cell cycle regulatory proteins in renal disease: role in hypertrophy, proliferation, and apoptosis. Am J Physiol Renal Physiol 278: F515-F529, 2000.
24. Sherr CJ and Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 13: 1501-1512, 1999.
25. Tian H, Wittmack EK, and Jorgensen TJ. p21WAF1/CIP1 antisense therapy radiosensitizes human colon cancer by converting growth arrest to apoptosis. Cancer Res 60: 679-684, 2000.
26. Togawa A, Yamamoto T, Suzuki H, Fukasawa H, Ohashi N, Fujigaki Y, Kitagawa K, Hattori T, Kitagawa M, and Hishida A. Ubiquitin-dependent degradation of Smad2 is increased in the glomeruli of rats with anti-thymocyte serum nephritis. Am J Pathol 163: 1645-1652, 2003.
27. Wang Y, Blandino G, Oren M, and Givol D. Induced p53 expression in lung line promotes cell senescence and differentially cytotoxicity of anti-cancer drugs. Oncogene 17: 1923-1930, 1998.
28. Yasuda H, Kato A, Miyaji T, Zhou H, Togawa T, and Hishida A. Insulin-like growth factor-I increases p21 expression and attenuates cisplatin-induced acute renal injury in rats. Clin Exp Nephrol 8: 27-35, 2004.
29. Zhou H, Miyaji T, Kato A, Fujigaki Y, Sano K, and Hishida A. Attenuation of cisplatin-induced acute renal failure is associated with the less apoptotic cell death. J Lab Clin Med 34: 649-658, 1999.
30. Zhou H, Kato A, Yasuda H, Miyaji T, Fujigaki Y, and Hishida A. The induction of cell cycle regulatory and DNA repair proteins in cisplatin-induced acute renal failure. Toxicol Appl Pharmacol 200: 111-120, 2004.