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Volumn 55, Issue 5, 2006, Pages 1276-1282

Metabolic sensors mediate hypoglycemic detection at the portal vein

Author keywords

BHB, hydroxybutyrate; CNS, central nervous system; DCA, dichloroacetic acid

Indexed keywords

3 HYDROXYBUTYRIC ACID; ADRENALIN; GLUCOSE; INSULIN; LACTIC ACID; NORADRENALIN; PYRUVIC ACID; LACTIC ACID DERIVATIVE;

EID: 33745328187     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db05-1665     Document Type: Article
Times cited : (23)

References (51)
  • 1
    • 0035665510 scopus 로고    scopus 로고
    • Hypoglycemia-associated autonomic failure in diabetes
    • Cryer PE: Hypoglycemia-associated autonomic failure in diabetes. Am J Physiol Endocrinol Metab 281:E1115-E1121, 2001
    • (2001) Am J Physiol Endocrinol Metab , vol.281
    • Cryer, P.E.1
  • 2
    • 0031006603 scopus 로고    scopus 로고
    • Hypoglycemia in the Diabetes Control and Complications Trial
    • The Diabetes Control and Complications Trial Research Group: Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 46:271-286, 1997
    • (1997) Diabetes , vol.46 , pp. 271-286
  • 3
    • 0020700793 scopus 로고
    • Abnormal glucose counterregulation in insulin-dependent diabetes mellitus: Interaction of anti-insulin antibodies and impaired glucagon and epinephrine secretion
    • Bolli G, de Feo P, Compagnucci P, Cartechini MG, Angeletti G, Santeusanio F, Brunetti P, Gerich JE: Abnormal glucose counterregulation in insulin-dependent diabetes mellitus: interaction of anti-insulin antibodies and impaired glucagon and epinephrine secretion. Diabetes 32:134-141, 1983
    • (1983) Diabetes , vol.32 , pp. 134-141
    • Bolli, G.1    De Feo, P.2    Compagnucci, P.3    Cartechini, M.G.4    Angeletti, G.5    Santeusanio, F.6    Brunetti, P.7    Gerich, J.E.8
  • 4
    • 0020584882 scopus 로고
    • Impaired counterregulation of hypoglycemia in insulin-dependent diabetes mellitus
    • Kleinbaum J, Shamoon H: Impaired counterregulation of hypoglycemia in insulin-dependent diabetes mellitus. Diabetes 32:493-498, 1983
    • (1983) Diabetes , vol.32 , pp. 493-498
    • Kleinbaum, J.1    Shamoon, H.2
  • 5
    • 0020674603 scopus 로고
    • Identification of type I diabetic patients at increased risk for hypoglycemia during intensive therapy
    • White NH, Skor DA, Cryer PE, Levandoski LA, Bier DM, Santiago JV: Identification of type I diabetic patients at increased risk for hypoglycemia during intensive therapy. N Engl J Med 308:485-491, 1983
    • (1983) N Engl J Med , vol.308 , pp. 485-491
    • White, N.H.1    Skor, D.A.2    Cryer, P.E.3    Levandoski, L.A.4    Bier, D.M.5    Santiago, J.V.6
  • 6
    • 0028282953 scopus 로고
    • Hypoglycemia-induced autonomic failure in IDDM is specific for stimulus of hypoglycemia and is not attributable to prior autonomic activation
    • Rattarasarn C, Dagogo-Jack S, Zachwieja JJ, Cryer PE: Hypoglycemia-induced autonomic failure in IDDM is specific for stimulus of hypoglycemia and is not attributable to prior autonomic activation. Diabetes 43:809-818, 1994
    • (1994) Diabetes , vol.43 , pp. 809-818
    • Rattarasarn, C.1    Dagogo-Jack, S.2    Zachwieja, J.J.3    Cryer, P.E.4
  • 8
    • 0028296222 scopus 로고
    • Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia
    • Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI: Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J Clin Invest 93:1677-1682, 1994
    • (1994) J Clin Invest , vol.93 , pp. 1677-1682
    • Borg, W.P.1    During, M.J.2    Sherwin, R.S.3    Borg, M.A.4    Brines, M.L.5    Shulman, G.I.6
  • 9
    • 0030851022 scopus 로고    scopus 로고
    • Novel glucosensor for hypoglycemic detection localized to the portal vein
    • Hevener AL, Bergman RN, Donovan CM: Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes 46:1521-1525, 1997
    • (1997) Diabetes , vol.46 , pp. 1521-1525
    • Hevener, A.L.1    Bergman, R.N.2    Donovan, C.M.3
  • 10
    • 0033957338 scopus 로고    scopus 로고
    • Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia
    • Hevener AL, Bergman RN, Donovan CM: Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes 49:8-12, 2000
    • (2000) Diabetes , vol.49 , pp. 8-12
    • Hevener, A.L.1    Bergman, R.N.2    Donovan, C.M.3
  • 11
    • 0028852712 scopus 로고
    • Hepatic denervation reduces adrenal catecholamine secretion during insulin-induced hypoglycemia
    • Lamarche L, Yamaguchi N, Peronnet F: Hepatic denervation reduces adrenal catecholamine secretion during insulin-induced hypoglycemia. Am J Physiol 268:R50-R57, 1995
    • (1995) Am J Physiol , vol.268
    • Lamarche, L.1    Yamaguchi, N.2    Peronnet, F.3
  • 12
    • 0026027379 scopus 로고
    • Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia
    • Donovan CM, Halter JB, Bergman RN: Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes 40:155-158, 1991
    • (1991) Diabetes , vol.40 , pp. 155-158
    • Donovan, C.M.1    Halter, J.B.2    Bergman, R.N.3
  • 15
    • 33644668567 scopus 로고    scopus 로고
    • Celiac-superior mesenteric ganglionectomy, but not vagotomy, suppresses the sympathoadrenal response to insulin-induced hypoglycemia
    • Fujita S, Donovan CM: Celiac-superior mesenteric ganglionectomy, but not vagotomy, suppresses the sympathoadrenal response to insulin-induced hypoglycemia. Diabetes 54:3258-3264, 2005
    • (2005) Diabetes , vol.54 , pp. 3258-3264
    • Fujita, S.1    Donovan, C.M.2
  • 16
    • 0028566199 scopus 로고
    • Effect of hyperketonemia and hyperlacticacidemia on symptoms, cognitive dysfunction, and counterregulatory hormone responses during hypoglycemia in normal humans
    • Veneman T, Mitrakou A, Mokan M, Cryer P, Gerich J: Effect of hyperketonemia and hyperlacticacidemia on symptoms, cognitive dysfunction, and counterregulatory hormone responses during hypoglycemia in normal humans. Diabetes 43:1311-1317, 1994
    • (1994) Diabetes , vol.43 , pp. 1311-1317
    • Veneman, T.1    Mitrakou, A.2    Mokan, M.3    Cryer, P.4    Gerich, J.5
  • 17
    • 0028082320 scopus 로고
    • Protection by lactate of cerebral function during hypoglycaemia
    • Maran A, Cranston I, Lomas J, Macdonald I, Amiel SA: Protection by lactate of cerebral function during hypoglycaemia. Lancet 343:16-20, 1994
    • (1994) Lancet , vol.343 , pp. 16-20
    • Maran, A.1    Cranston, I.2    Lomas, J.3    Macdonald, I.4    Amiel, S.A.5
  • 18
    • 0025062565 scopus 로고
    • Hypothalamic neuronal activity responses to 3-hydroxybutyric acid, an endogenous organic acid
    • Minami T, Shimizu N, Duan S, Oomura Y: Hypothalamic neuronal activity responses to 3-hydroxybutyric acid, an endogenous organic acid. Brain Res 509:351-354, 1990
    • (1990) Brain Res , vol.509 , pp. 351-354
    • Minami, T.1    Shimizu, N.2    Duan, S.3    Oomura, Y.4
  • 19
    • 12144275681 scopus 로고    scopus 로고
    • Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus
    • Song Z, Routh VH: Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 54:15-22, 2005
    • (2005) Diabetes , vol.54 , pp. 15-22
    • Song, Z.1    Routh, V.H.2
  • 20
    • 0032829063 scopus 로고    scopus 로고
    • Hypothalamic glucose sensor: Similarities to and differences from pancreatic β-cell mechanisms
    • Yang XJ, Kow LM, Funabashi T, Mobbs CV: Hypothalamic glucose sensor: similarities to and differences from pancreatic β-cell mechanisms. Diabetes 48:1763-1772, 1999
    • (1999) Diabetes , vol.48 , pp. 1763-1772
    • Yang, X.J.1    Kow, L.M.2    Funabashi, T.3    Mobbs, C.V.4
  • 21
    • 0347360368 scopus 로고    scopus 로고
    • Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose
    • Yang XJ, Kow LM, Pfaff DW, Mobbs CV: Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose. Diabetes 53:67-73, 2004
    • (2004) Diabetes , vol.53 , pp. 67-73
    • Yang, X.J.1    Kow, L.M.2    Pfaff, D.W.3    Mobbs, C.V.4
  • 24
    • 0025162079 scopus 로고
    • Glucose-induced excitation of hypothalamic neurones is mediated by ATP-sensitive K+ channels
    • Ashford ML, Boden PR, Treherne JM: Glucose-induced excitation of hypothalamic neurones is mediated by ATP-sensitive K+ channels. Pflugers Arch 415:479-483, 1990
    • (1990) Pflugers Arch , vol.415 , pp. 479-483
    • Ashford, M.L.1    Boden, P.R.2    Treherne, J.M.3
  • 25
    • 0024306457 scopus 로고
    • Endurance training enhances lactate clearance during hyperlactatemia
    • Donovan CM, Pagliassotti MJ: Endurance training enhances lactate clearance during hyperlactatemia. Am J Physiol 257:E782-E789, 1989
    • (1989) Am J Physiol , vol.257
    • Donovan, C.M.1    Pagliassotti, M.J.2
  • 28
    • 0023587133 scopus 로고
    • Optimized kinetic method for automated determination of beta-hydroxybutyrate
    • Koch DD, Feldbruegge DH: Optimized kinetic method for automated determination of beta-hydroxybutyrate. Clin Chem 33:1761-1766, 1987
    • (1987) Clin Chem , vol.33 , pp. 1761-1766
    • Koch, D.D.1    Feldbruegge, D.H.2
  • 30
    • 0017622228 scopus 로고
    • Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine
    • Peuler JD, Johnson GA: Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine. Life Sci 21:625-636, 1977
    • (1977) Life Sci , vol.21 , pp. 625-636
    • Peuler, J.D.1    Johnson, G.A.2
  • 31
    • 0019069404 scopus 로고
    • Reference sample microsphere method: Cardiac output and blood flows in conscious rat
    • Ishise S, Pegram BL, Yamamoto J, Kitamura Y, Frohlich ED: Reference sample microsphere method: cardiac output and blood flows in conscious rat. Am J Physiol 239:H443-H449, 1980
    • (1980) Am J Physiol , vol.239
    • Ishise, S.1    Pegram, B.L.2    Yamamoto, J.3    Kitamura, Y.4    Frohlich, E.D.5
  • 32
    • 0029927343 scopus 로고    scopus 로고
    • Metabolic coupling between glia and neurons
    • Tsacopoulos M, Magistretti PJ: Metabolic coupling between glia and neurons. J Neurosci 16:877-885, 1996
    • (1996) J Neurosci , vol.16 , pp. 877-885
    • Tsacopoulos, M.1    Magistretti, P.J.2
  • 33
    • 0345700729 scopus 로고    scopus 로고
    • Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation
    • Borg MA, Tamborlane WV, Shulman GI, Sherwin RS: Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation. Diabetes 52:663-666, 2003
    • (2003) Diabetes , vol.52 , pp. 663-666
    • Borg, M.A.1    Tamborlane, W.V.2    Shulman, G.I.3    Sherwin, R.S.4
  • 34
    • 27844491008 scopus 로고    scopus 로고
    • Lactate is a critical "sensed" variable in caudal hindbrain monitoring of CNS metabolic stasis
    • Patil GD, Briski KP: Lactate is a critical "sensed" variable in caudal hindbrain monitoring of CNS metabolic stasis. Am J Physiol Regul Integr Comp Physiol 289:R1777-R1786, 2005
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289
    • Patil, G.D.1    Briski, K.P.2
  • 35
    • 0035187234 scopus 로고    scopus 로고
    • Effects of lactate on glucose-sensing neurons in the solitary tract nucleus
    • Himmi T, Perrin J, Dallaporta M, Orsini JC: Effects of lactate on glucose-sensing neurons in the solitary tract nucleus. Physiol Behav 74:391-397, 2001
    • (2001) Physiol Behav , vol.74 , pp. 391-397
    • Himmi, T.1    Perrin, J.2    Dallaporta, M.3    Orsini, J.C.4
  • 37
    • 0037107408 scopus 로고    scopus 로고
    • Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: Evidence for ATP-independent control of ATP-sensitive K(+) channels
    • Ainscow EK, Mirshamsi S, Tang T, Ashford ML, Rutter GA: Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: evidence for ATP-independent control of ATP-sensitive K(+) channels. J Physiol 544:429-445, 2002
    • (2002) J Physiol , vol.544 , pp. 429-445
    • Ainscow, E.K.1    Mirshamsi, S.2    Tang, T.3    Ashford, M.L.4    Rutter, G.A.5
  • 38
    • 0030748260 scopus 로고    scopus 로고
    • Signal transduction mechanisms in nutrient-induced insulin secretion
    • Prentki M, Tornheim K, Corkey BE: Signal transduction mechanisms in nutrient-induced insulin secretion. Diabetologia 40 (Suppl. 2):S32-S41, 1997
    • (1997) Diabetologia , vol.40 , Issue.2 SUPPL.
    • Prentki, M.1    Tornheim, K.2    Corkey, B.E.3
  • 39
    • 0026733643 scopus 로고
    • Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion
    • Prentki M, Vischer S, Glennon MC, Regazzi R, Deeney JT, Corkey BE: Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion. J Biol Chem 267:5802-5810, 1992
    • (1992) J Biol Chem , vol.267 , pp. 5802-5810
    • Prentki, M.1    Vischer, S.2    Glennon, M.C.3    Regazzi, R.4    Deeney, J.T.5    Corkey, B.E.6
  • 40
    • 0030810982 scopus 로고    scopus 로고
    • Metabolic fate of glucose in purified islet cells: Glucose-regulated anaplerosis in beta cells
    • Schuit F, De Vos A, Farfari S, Moens K, Pipeleers D, Brun T, Prentki M: Metabolic fate of glucose in purified islet cells: glucose-regulated anaplerosis in beta cells. J Biol Chem 272:18572-18579, 1997
    • (1997) J Biol Chem , vol.272 , pp. 18572-18579
    • Schuit, F.1    De Vos, A.2    Farfari, S.3    Moens, K.4    Pipeleers, D.5    Brun, T.6    Prentki, M.7
  • 41
    • 0033810262 scopus 로고    scopus 로고
    • Glucose sensing by the hepatoportal sensor is GLUT2-dependent: In vivo analysis in GLUT2-null mice
    • Burcelin R, Dolci W, Thorens B: Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice. Diabetes 49:1643-1648, 2000
    • (2000) Diabetes , vol.49 , pp. 1643-1648
    • Burcelin, R.1    Dolci, W.2    Thorens, B.3
  • 42
    • 0028101926 scopus 로고
    • Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut
    • Jetton TL, Liang Y, Pettepher CC, Zimmerman EC, Cox FG, Horvath K, Matschinsky FM, Magnuson MA: Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut. J Biol Chem 269:3641-3654, 1994
    • (1994) J Biol Chem , vol.269 , pp. 3641-3654
    • Jetton, T.L.1    Liang, Y.2    Pettepher, C.C.3    Zimmerman, E.C.4    Cox, F.G.5    Horvath, K.6    Matschinsky, F.M.7    Magnuson, M.A.8
  • 43
    • 0015985999 scopus 로고
    • Effects of ketone body infusion on hypoglycemic reaction in postabsorptive dogs
    • Flatt JP, Blackburn GL, Randers G, Stanbury JB: Effects of ketone body infusion on hypoglycemic reaction in postabsorptive dogs. Metabolism 23:151-158, 1974
    • (1974) Metabolism , vol.23 , pp. 151-158
    • Flatt, J.P.1    Blackburn, G.L.2    Randers, G.3    Stanbury, J.B.4
  • 44
    • 0017361217 scopus 로고
    • Homeostasis during hypoglycemia: Central control of adrenal secretion and peripheral control of feeding
    • Stricker EM, Rowland N, Saller CF, Friedman MI: Homeostasis during hypoglycemia: central control of adrenal secretion and peripheral control of feeding. Science 196:79-81, 1977
    • (1977) Science , vol.196 , pp. 79-81
    • Stricker, E.M.1    Rowland, N.2    Saller, C.F.3    Friedman, M.I.4
  • 45
    • 0027418622 scopus 로고
    • Transport of lactate and other monocarboxylates across mammalian plasma membranes
    • Poole RC, Halestrap AP: Transport of lactate and other monocarboxylates across mammalian plasma membranes. Am J Physiol 264:C761-C782, 1993
    • (1993) Am J Physiol , vol.264
    • Poole, R.C.1    Halestrap, A.P.2
  • 46
    • 0015850411 scopus 로고
    • Infusion of 2-deoxy-D-glucose into the hepatic-portal system causes eating: Evidence for peripheral glucoreceptors
    • Novin D, VanderWeele DA, Rezek M: Infusion of 2-deoxy-D-glucose into the hepatic-portal system causes eating: evidence for peripheral glucoreceptors. Science 181:858-860, 1973
    • (1973) Science , vol.181 , pp. 858-860
    • Novin, D.1    VanderWeele, D.A.2    Rezek, M.3
  • 47
    • 0002959403 scopus 로고
    • Glucose sensitive afferent nerve fibers in the liver and regulation of blood glucose
    • Niijima A: Glucose sensitive afferent nerve fibers in the liver and regulation of blood glucose. Brain Res Bull 5:175-179, 1980
    • (1980) Brain Res Bull , vol.5 , pp. 175-179
    • Niijima, A.1
  • 48
    • 0014677275 scopus 로고
    • Afferent impulse discharges from glucoreceptors in the liver of the guinea pig
    • Niijima A: Afferent impulse discharges from glucoreceptors in the liver of the guinea pig. Ann N Y Acad Sci 157:690-700, 1969
    • (1969) Ann N Y Acad Sci , vol.157 , pp. 690-700
    • Niijima, A.1
  • 49
    • 0025309016 scopus 로고
    • Vagal sensory neurons are required for lipoprivic but not glucoprivic feeding in rats
    • Ritter S, Taylor JS: Vagal sensory neurons are required for lipoprivic but not glucoprivic feeding in rats. Am J Physiol 258:R1395-R1401, 1990
    • (1990) Am J Physiol , vol.258
    • Ritter, S.1    Taylor, J.S.2
  • 50
    • 0022351121 scopus 로고
    • Regulation of food intake by hepatic oxidative metabolism
    • Langhans W, Egli G, Scharrer E: Regulation of food intake by hepatic oxidative metabolism. Brain Res Bull 15:425-428, 1985
    • (1985) Brain Res Bull , vol.15 , pp. 425-428
    • Langhans, W.1    Egli, G.2    Scharrer, E.3


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