Transport characteristics of a novel peptide transporter 1 substrate, antihypotensive drug midodrine, and its amino acid derivatives

Journal of Pharmacology and Experimental Therapeutics

Volumn 318, Issue 1, 2006, Pages 455-460

  Tsuda, Masahiro ^a   Terada, Tomohiro ^a   Irie, Megumi ^a   Katsura, Toshiya ^a   Niida, Ayumu ^b   Tomita, Kenji ^b   Fujii, Nobutaka ^b   Inui, Ken Ichi ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2',5' DIMETHOXYPHENYL) 2 AMINOETHANOL; AMINO ACID; CATION; CYCLACILLIN; CYSTEINE; ETHANOLAMINE DERIVATIVE; GLUTAMIC ACID; GLYCINE; GLYCYLSARCOSINE; HYPERTENSIVE AGENT; ISOLEUCINE; LYSINE; MIDODRINE; PEPTIDE TRANSPORTER 1; PHENYLALANINE; PROLINE; TRITIUM; TYROSINE; UNCLASSIFIED DRUG; VALINE; WATER;

ALKALINITY; ANIMAL CELL; AREA UNDER THE CURVE; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG EFFECT; DRUG INHIBITION; DRUG STRUCTURE; DRUG TRANSPORT; DRUG UPTAKE; HUMAN; HUMAN CELL; INTESTINE; MAXIMUM ALLOWABLE CONCENTRATION; NONHUMAN; OOCYTE; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACIDS; ANIMALS; CACO-2 CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; HYPOTENSION, ORTHOSTATIC; MEMBRANE TRANSPORT PROTEINS; MIDODRINE; OOCYTES; PROTEIN TRANSPORT; RATS; XENOPUS LAEVIS;

EID: 33745254504     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.102830     Document Type: Article

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