β4 Integrin and other Schwann cell markers in axonal neuropathy

GLIA

Volumn 17, Issue 4, 1996, Pages 294-306

  Quattrini, Angelo ^a   Previtali, Stefano ^a   Feltri, Maria Laura ^a   Canal, Nicola ^a   Nemni, Raffaello ^a   Wrabetz, Lawrence ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Axonal regeneration; GFAP; Neurofilament; P0 glycoprotein; Wallerjan degeneration

Indexed keywords

EID: 0029768687     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1098-1136(199608)17:4<294::aid-glia4>3.0.co;2-#     Document Type: Article

References (62)

1. Aguayo, A.J., Epps, J., Charron, L., and Bray, G.M. (1976) Multipotentiality of Schwann cells in cross-anastomosed and grafted myelinated and unmyelinated nerves: Quantitative microscopy and radioautography. Brain Res., 104:1-20.
2. Archelos, J.J., Roggenbuck, K., Schneider-Schaulies, J., Linington, C., Toyka, K.V., and Hartung, H.P. (1993) Production and characterization of monoclonal antibodies to the extracellular domain of P0. J. Neurosci. Res., 35:46-53.
3. Carter, W.G., Kaur, P., Gil, S.G., Gahr, P.J., and Wayner, E.A. (1990) Distinct functions for integrins alpha3-beta1 in focal adhesions and alpha6-beta4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes: Relation to hemidesmosomes. J. Cell Biol., 111:3141-3154.
4. Chandross, K.J., Chanson, M., Spray, D.C., and Kessler, JA (1995) Transforming growth factor-beta 1 and forskolin modulate gap junctional communication and cellular phenotype of cultured Schwann cells. J. Neurosci., 15:262-273.
5. Dyck, P.J., Giannini, C., and Lais, A. (1992) Pathological alterations of nerves. In: Peripheral Neuropathy. P.J. Dyck, P.K. Thomas, J. Griffin, P.A. Low, and J.F. Poduslo, eds. W.B. Saunders, Philadelphia, pp. 514-595.
6. Einheber, S., Milner, T., Giancotti, F., and Salzer, J. (1993) Axonal regulation of Schwann cell integrin expression suggests a role for alpha6 beta4 in myelination. J. Cell Biol., 123:1223-1236.
7. Einheber, S., Hannocks, M.-J., Metz, C.N. Rifkin, D.B., and Salzar, J.L. (1995) Transforming growth factor-β1 regulates axon/Schwann cell interactions. J. Cell Biol., 129:443-458.
8. Engvall, E., Earwicker, D., Haaparanta, T., Ruoslahti, E., and Sanes, J.R. (1990) Distribution and isolation of four laminin variants; Tissue restricted distribution of heterotrimers assembled from five different subunits. Cell Regul, 1:731-740.
9. Feltri, M.L., Scherer, S.S., Nemni, R., Kamholz, J., Vogelbacker, H., Scott, M.O., Canal, N., Quaranta, V., and Wrabetz, L. (1994) β4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent. Development, 120:1287-1301.
10. Fernandez-Valle, C., Gwynn, L., Wood, P.M., Carbonetto, S., and Bunge, M.B. (1994) Anti-beta 1 integrin antibody inhibits Schwann cell myelination. J. NeurobioL, 25:1207-1226.
11. Griffin, J.W. and Hoffman, P.N. (1992) Degeneration and regeneration in the peripheral nervous system. In: Peripheral Neuropathy. P.J. Dyck, P.K. Thomas, J. Griffin, P.A. Low, and J.F. Poduslo, eds. W.B. Saunders, Philadelphia, pp. 361-376.
12. Guenard, V., Gwynn, L.A., and Wood, P.M. (1995) Transforming growth factor-beta blocks myelination but not ensheathment of axons by Schwann cells in vitro. J. Neurosci., 15:419-428.
13. Gupta, S.K., Poduslo, J.F., and Mezei, C. (1988) Temporal changes in P0 and MBP gene expression after crush-injury of the adult peripheral nerve. Brain Res., 464:133-141.
14. Hall, S.M. (1986) The effect of inhibiting Schwann cell mitosis on the reinnervation of acellular autografts in the peripheral nervous system of the mouse. Neuropathol. Appl. Neurobiol., 12:401-414.
15. Hanemann, C.O., Stall, G., D'Urso, D., Fricke, W., Martin, J.J., Van Broeckhoven, C., Mancardi, G.L., Bartke, I., and Muller, H.W. (1994) Peripheral myelin protein-22 expression in Charcot-Marie-Tooth disease type 1a sural nerve biopsies. J. Neurosci. Res., 37:654-659.
16. Heumann, R., Lindholm, D., Bandtlow, C., Meyer, M., Radeke, M.J., Misko, T.P., Shooter, E., and Thoenen, H. (1987) Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: Role of macrophages. Proc. Natl. Acad. Sci. USA, 84:8735-8739.
17. Hynes, R.O. (1992) Integrals: Versatility, modulation, and signalling in cell adhesion. Cell, 69:11-25.
18. Ide, C., Tohyama, K., Yokota, R., Nitatori, T., and Onodera, S. (1983) Schwann cell basal lamina and nerve regeneration. Brain Res., 288:61-75.
19. Jaakkola, S., Savunen, O., Halme, T., Uitto, J., and Peltonen, J. (1993) Basement membranes during development of human nerve -Schwann cells and perineurial cells display marked changes in their expression profiles for laminin subunits and betal and beta4 integrins. J. Neurocytol., 22:215-230.
20. Jessen, K.R., Mirsky, R., and Morgan, L. (1987) Axonal signals regulate the differentiation of non-myelin-fonning Schwann cells: An immunohistochemical study of galactocerebroside in transected and regenerating nerves. J. Neurosci., 7:3362-3369.
21. Jessen, K.R., Morgan, L., Stewart, H.J.S., and Mirsky, R. (1990) Three markers of adult non-myelin-forming Schwann cells, 217c (Ran-1), A5E3 and GFAP: Development and regulation by neuron-Schwann cell interactions. Development, 109:91-103.
22. Jones, J.C.R., Kurpakus, M.A., Cooper, H.M., and Quaranta, V. (1991) A function for the integrin α6β4 in the hemidesmosome. Cell Regul., 2:427-438.
23. Kida, E., Barcikowska, M., Joachimowicz-Jaskowiak, E., Michalska, T., Siekierzynska, A., Walasik, A., Roszkowski, K., and Figura-Chojak, E. (1994) Subacute sensory neuronopathy in small cell cancer of the lung. Immunocytochemical study of 2 cases. Clin. Neuropathol., 13:64-70.
24. Kuecherer-Ehret, A., Graeber, M.B., Edgar, D.,Thoenen, H., and Kreutzberg, G.W. (1990) Immunoelectron microscopic localization of laminin in normal and regenerating mouse sciatic nerve. J. Neurocytol., 19:101-109.
25. Lee, E.C., Lotz, M.M., Steele, G.D., and Mercurio, A.M. (1992) The integrin alpha6beta4 is a laminin receptor. J. Cell Biol., 117:671-678.
26. Lemke, G. (1992) Myelin and myelination. In: Molecular Neurobiology. Z.W. Hall, ed. Sinauer Associates, Sunderland, MA, pp. 281-309.
27. Lemke, G. (1993) The molecular genetics of myelination: An update. Glia, 7:263-271.
28. Lemke, G. and Chao, M. (1988) Axons regulate Schwann cell expression of the major myelin and NGF receptor genes. Development, 102:499-504.
29. Mancardi, G.L., Cadoni, A., Zicca, A., Schenone, A., Tabaton, M., De Martini, I., and Zaccheo, D. (1988) HLA-DR Schwann cell reactivity in peripheral neuropathies of different origins. Neurology, 38:848-851.
30. Mancardi, G.L., Cadoni, A., Tabaton, M., Schenone, A., Zicca, A., De Martini, I., Bianchini, D., Damiani, G., and Zaccheo, D. (1991) Schwann cell GFAP expression increases in axonal neuropathies. J. Neurol. Sci., 102:177-183.
31. Manthorpe, M., Engvall, E., Ruoslahti, E., Longo, F.M., Davis, G.E., and Varon, S. (1983) Laminin promotes neuritic regeneration from cultured peripheral and central neurons. J. Cell Biol., 97:1882-1890.
32. Mechtersheimer, G., Barth, T., Quentmeier, A., and Moller, P. (1994) Differential expression of beta 1, beta 3, and beta 4 integrin subunits in nonneoplastic neural cells of the peripheral and autonomic nervous system and in tumors derived from these cells. Lab. Invest., 70:740-752.
33. Mews, M. and Meyer, M. (1993) Modulation of Schwann cell phenotype by TGF-beta 1: Inhibition of PO mRNA expression and downregulation of the low affinity NGF receptor. Glia, 8:208-217.
34. Mirsky, R. and Jessen, K.R. (1990) Schwann cell development and the regulation of myelination. Semin. Neurosci., 2:423-435.
35. Mirsky, R., Winter, J., Abney, E., Pruss, R.M., Gavrilovic, J., and Raff, M.C. (1980) Myelin-specific proteins and glycolipids in rat Schwann cells and oligodendrocytes in culture. J. Cell Biol., 84:483-494.
36. Mitchell, G.W., Williams, G.S., Bosch, E.P., and Hart, M.N. (1991) Class II antigen expression in peripheral neuropathies. J. Neurol. Sci., 102:170-176.
37. Morgan, L., Jessen, K.R., and Mirsky, R. (1994) Negative regulation of the P0 gene in Schwann cells: Suppression of P0 mRNA and protein induction in cultured Schwann cells by FGF2 and TGF beta 1, TGF beta 2 and TGF beta 3. Development, 120:1399-1409.
38. Natali, P.G., Nicotra, M.R., Bigotti, A., and Demartino, C. (1992) Localization of the alpha6 and beta4 integrin subunits in normal human non-lyraphoid tissues. J. Cell Sci., 103:1243.
39. Niessen, C.M., Cremona, O., Daams, H., Ferraresi, S., Sonnenberg, A., and Marchisio, P.C. (1994a) Expression of the integrin α6β4 in peripheral nerves: Localization in Schwann and perineurial cells and different variants of the β4 subunit. J. Cell Sci., 107:543-552.
40. Niessen, C.M., Hogervorst, F., Jaspars, L.H., De Melker, A.A., Deiwel, G.O., Hulsman, E.H.M., Kuikman, I., and Sonnenberg, A. (1994b) The alpha6-beta4 integrin is a receptor for both laminin and kalinin. Exp. Cell Res., 211:360-367.
41. Sanes, J.R., Engvall, E., Butkowski, R., and Hunter, D.D. (1990) Molecular heterogeneity of basal laminae: Isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. J. Cell Biol., 111:1685-1699.
42. Scarpini, E., Lisak, R.P., Beretta, S., Velicogna, M., Doronzo, R., Moggio, M., Jann, S., and Scarlato, G. (1990) Quantitative assessment of class II molecules in normal and pathological nerves. Immunocytochemical studies in vivo and in tissue culture. Brain, 113:659-675.
43. Scherer, S.S. and Asbury, A.K. (1993) Inherited axonal neuropathies. In: The Molecular and Genetic Basis of Neurological Disease. R.N. Rosenberg, S.B. Prusiner, S. DiMauro, R.L. Barchi, and L.M. Kunkle, eds. Butterworth-Heinemann, London, pp. 899-921.
44. Scherer, S.S., Xu, Y.-T., Roling, D., Wrabetz, L., Feltri, M.L., and Kamholz, J. (1994) Expression of growth-associated protein-43kD in Schwann cells is regulated by axon-Schwann cell interactions and cAMP. J. Neurosci. Res., 38:575-589.
45. Schneiderschaulies, J., Kirchhoff, F., Archelos, J., and Schachner, M. (1991) Down-regulation of myelin-associated glycoprotein on Schwann cells by interferon-gamma and tumor necrosis factor-alpha affects neurite outgrowth. Neuron, 7:995-1005.
46. Sciacco, M., Scarpini, E., Baron, P.L., Doronzo, R., Moggio, M., Passerini, D., and Scarlato, G. (1992) Sural nerve immunoreactivity for nerve growth factor receptor in a case of localized hypertrophic neuropathy. Acta Neuropathol., 83:547-553.
47. Son, Y.J. and Thompson, W.J. (1995) Schwann cell processes guide regeneration of peripheral axons. Neuron, 14:126-132.
48. Sonnenberg, A. (1993) Integrins and their ligands. Curr. Top. Microbiol Immunol., 184:7-35.
49. Sonnenberg, A.C., Linders, J.T., Daams, J.H., and Kennel, S.J. (1990) The α6β1 (VLA-6) and α6β4 protein complexes: Tissue distribution and biochemical properties. J. Cell Sci., 96:207-217.
50. Sonnenberg, A., Calafat, J., Janssen. H., Daams, H., Van der Raaij-Helmer, L.M.H., Falcioni, R., Kennel, S.J., Aplin, J.D., Baker, J., Liozidou, M., and Garrod, D. (1991) Integrin α6β4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement adhesion. J. Cell Biol., 113:907-917.
51. Spinardi, L., Einheber, S., Cullen, T., Milner, T.A., and Giancotti, F.G. (1995) A recombinant tail-less integrin β4 subunit disrupts hemidesmosomes, but does not suppress α6β4-mediated cell adhesion to laminins. J. Cell Biol., 129:473-487.
52. Stepp, M.A., Spurr-Michaud, S., Tisdale, A., Elwell, J., and Gipson, I.K. (1990) α6β4 integrin heterodimer is a component of hemidesmosomes. Proc. Natl. Acad. Sci. USA, 87:8970-8974.
53. Tamura, R.N., Cooper, H.M., Collo, G., and Quaranta, V. (1991) Cell-type specific integrin variants with alternative α6 chain cytoplasmic domains. Proc. Natl. Acad. Sci. USA, 88:10183-10187.
54. Taniuchi, M., Clark, H.B., and Johnson, E.M., Jr. (1986) Induction of nerve growth factor receptor in Schwann cells after axotomy. Proc. Natl. Acad. Sci. USA, 83:4094-4098.
55. Thomson, C.E., Griffiths, I.R., McCulloch, M.C., Kyriakides, E., Barrie, J.A., and Montague, P. (1993) In vitro studies of axonally-regulated Schwann cell genes during Wallerian degeneration. J. Neurocytol., 22:590-602.
56. Tozeren, A., Kleinman, H.K., Wu, S., Mercurio, A.M., and Byers, S.W. (1994) Integrin alpha(6)beta(4) mediates dynamic interactions with laminin. J. Cell Sci., 107:3153-3163.
57. Trapp, B.D., Hauer, P., and Lemke, G. (1988) Axonal regulation of myelin protein mRNA levels in actively myelinating Schwann cells. J. Neurosci., 8:3515-3521.
58. Vidal, F., Aberdam, D., Miquel, C., Christiano, A.M., Pulkkinen, L., Uitto, J., Ortonne, J.-P., and Meneguzzi, G. (1995) Integrin β4 mutations associated with junctional epidermolysis bullosa with pyloric atresia. Nat. Genet., 10:229-234.
59. Wang, G.Y., Hirai, K., and Shimada, H. (1992) The role of laminin, a component of Schwann cell basal lamina, in rat sciatic nerve regeneration within antiserum-treated nerve grafts. Brain Res., 570:116-125.
60. Weinberg, H.J. and Spencer, P.S. (1976) Studies on the control of myelinogenesis. II. Evidence for neuronal regulation of myelin production. Brain Res., 113:363-378.
61. Williams, L.L., Kissel, J.T., Shannon, B.T., Wright, F.S., and Mendell, J.R. (1992) Expression of Schwann cell and peripheral T-cell activation epitopes in hereditary motor and sensory neuropathy. J. Neuroimmunol., 36:147-155.
62. Yoshikawa, H., Nishimura, T., Nakatsuji, Y., Fujimura, H., Himoro, M., Hayasaka, K., Sakoda, S., and Yanagihara, T. (1994) Elevated expression of messenger RNA for peripheral myelin protein 22 in biopsied peripheral nerves of patients with Charcot-Marie-Tooth disease type 1A. Ann. Neurol., 35:445-450.