Cell-specificity of transforming growth factor-β response is dictated by receptor bioavailability

Journal of Molecular Endocrinology

Volumn 36, Issue 3, 2006, Pages 591-600

  Suszko, Magdalena I ^a   Woodruff, Teresa K ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; FOLLITROPIN; GROWTH HORMONE; LIGAND; PROLACTIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LINE; CELL SPECIFICITY; CELL SURFACE; CONTROLLED STUDY; FEMALE; GENETIC TRANSCRIPTION; HORMONE SYNTHESIS; HYPOPHYSIS; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STIMULATION;

ACTIVIN RECEPTORS, TYPE I; ACTIVINS; ANIMALS; CELL LINE; FEMALE; FOLLICLE STIMULATING HORMONE, BETA SUBUNIT; GENE EXPRESSION REGULATION; GONADOTROPHS; HUMANS; MICE; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, SMALL INTERFERING; SMAD3 PROTEIN; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 33745209695     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.1.01936     Document Type: Article

References (25)

1. Alexander JM, Bikkal HA, Zervas NT, Laws ER Jr & Klibanski A 1996 Tumor-specific expression and alternate splicing of messenger ribonucleic acid encoding activin/transforming growth factor-beta receptors in human pituitary adenomas. Journal of Clinical Endocrinology and Metabolism 81 783-790.
2. Bernard DJ, Chapman SC & Woodruff TK 2001 An emerging role for co-receptors in inhibin signal transduction. Molecular and Cellular Endocrinology 180 55-62.
3. Bristol SK & Woodruff TK 2004 Follicle-restricted compartmentalization of transforming growth factor beta superfamily ligands in the feline ovary. Biology of Reproduction 70 846-859.
4. Carroll RS, Corrigan AZ, Gharib SD, Vale W & Chin WW 1989 Inhibin, activin, and follistatin: regulation of follicle-stimulating hormone messenger ribonucleic acid levels. Molecular Endocrinology 3 1969-1976.
5. Chapman SC & Woodruff TK 2001 Modulation of activin signal transduction by inhibin B and inhibin-binding protein (INhBP). Molecular Endocrinology 15 668-679.
6. Chen Y, Bhushan A & Vale W 1997 Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase [published erratum appears in PNAS 1998 95 1968]. PNAS 94 12938-12943.
7. Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S & Gauthier JM 1998 Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO Journal 17 3091-3100.
8. Gregory SJ, Lacza CT, Detz AA, Xu S, Petrillo LA & Kaiser UB 2005 Synergy between activin A and GnRH in transcriptional activation of the rat follicle-stimulating hormone beta (FSHβ) gene. Molecular Endocrinology 19 237-254.
9. Gurdon JB & Bourillot PY 2001 Morphogen gradient interpretation. Nature 413 797-803.
10. Jeruss JS, Santiago JY & Woodruf TK 2003 Localization of activin and inhibin subunits, receptors and SMADs in the mouse mammary gland. Molecular and Cellular Endocrinology 203 185-196.
11. Krummen LA & Baldwin DM 1988 Regulation of luteinizing hormone subunit biosynthesis in cultured male anterior pituitary cells: effects of gonadotropin-releasing hormone and testosterone. Endocrinology 123 1868-1878.
12. Lewis KA, Gray PC, Blount AL, MacConell LA, Wiater E, Bilezikjian LM & Vale W 2000 Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature 404 411-414.
13. Lu Z, Murray JT, Luo W, Li H, Wu X, Xu H, Backer JM & Chen YG 2002 Transforming growth factor beta activates Smad2 in the absence of receptor endocytosis. Journal of Biological Chemistry 277 29363-29368.
14. Nagarajan RP & Chen Y 2000 Structural basis for the functional difference between Smad2 and Smad3 in FAST-2 (forkhead activin signal transducer-2)-mediated transcription. Biochemical Journal 350 253-259.
15. Pangas SA & Woodruff TK 2002 Production and purification of recombinant human inhibin and activin. Journal of Endocrinology 172 199-210.
16. Razani B, Zhang XL, Bitzer M, von Gersdorff G, Bottinger EP & Lisanti MP 2001 Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor. Journal of Biological Chemistry 276 6727-6738.
17. Shi Y & Massague J 2003 Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113 685-700.
18. Suszko MI, Lo DJ, Suh H, Camper SA & Woodruff TK 2003 Regulation of the rat follicle-stimulating hormone beta-subunit promoter by activin. Molecular Endocrinology 17 318-332.
19. Suszko MI, Balkin DM, Chen Y & Woodruff TK 2005 Smad3 mediates activin-induced transcription of follicle-stimulating hormone β-subunit gene. Molecular Endocrinology 19 1849-1858.
20. Weiss J, Guendner MJ, Halvorson LM & Jameson JL 1995 Transcriptional activation of the follicle-stimulating hormone beta-subunit gene by activin. Endocrinology 136 1885-1891.
21. Wiater E & Vale W 2003 Inhibin is an antagonist of bone morphogenetic protein signaling. Journal of Biological Chemistry 278 7934-7941.
22. Wilfinger WW, Larsen WJ, Downs TR & Wilbur DL 1984 An in vitro model for studies of intercellular communication in cultured rat anterior pituitary cells. Tissue Cell 16 483-497.
23. Yamashita H, Okadome T, Franzen P, ten Dijke P, Heldin CH & Miyazono K 1995 A rat pituitary tumor cell line (GH3) expresses type I and type II receptors and other cell surface binding protein(s) for transforming growth factor-beta. Journal of Biological Chemistry 270 770-774.
24. Zakaria MM, Jeong KH, Lacza C & Kaiser UB 2002 Pituitary homeobox 1 activates the rat FSH beta (rFSHbeta) gene through both direct and indirect interactions with the rFSHbeta gene promoter. Molecular Endocrinology 16 1840-1852.
25. Zwijsen A, Verschueren K & Huylebroeck D 2003 New intracellular components of bone morphogenetic protein/Smad signaling cascades. FEBS Letters 546 133-139.