Self-disproportionation of enantiomers of (R)-ethyl 3-(3,5-dinitrobenzamido)-4,4,4-trifluorobutanoate on achiral silica gel stationary phase

Journal of Fluorine Chemistry

Volumn 127, Issue 4-5 SPEC. ISS., 2006, Pages 597-603

  Soloshonok, Vadim A ^a   Berbasov, Dmitrii O ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

Amino acids and derivatives; Achiral phase chromatography; Chirality; Fluorine and compounds; Self disproportionation of enantiomers; Separations

Indexed keywords

EID: 33745192709     PISSN: 00221139     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfluchem.2005.11.004     Document Type: Article

References (62)

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62. Taking into account a report by Katagiri et al. on strong enantiomer self-disproportionation of isopropyl 3,3,3-trifluoro-2-hydroxypropanoate during distillation, one may envision that amplification of this phenomenon by a trifluoromethyl group may be of much general nature and other achiral methods available for separation of organic compounds can be applied. In particular, our next goal will be studying the enantiomer self-disproportionation of various trifluoromethyl-containing compounds under sublimation conditions. For Katagiri's original publication, see:. Katagiri T., Yoda C., Furuhashi K., Ueki K., Kubota T. Chem. Lett. 2 (1996) 115-116